JP2008184395A - Anti-perspiration and deodorization cosmetic, and method for producing the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic having an anti-perspiration effect and a deodorization cosmetic, prepared by blending sake lees extract including rice-fermented liquid (including the same originated from deep ocean water) and an extract of brown algae such as sea oak, etc., and having an ALP (alkaliphosphatase) inhibitory activity and/or nonenal production-preventing activity, aromatic property, astringent property, antibacterial property and anti-perspiration activity. <P>SOLUTION: This cosmetic is the deodorization cosmetic obtained by blending sake lees extract containing the rice fermented liquid having the ALP inhibitory activity and/or the brown algae extract, and also blending a plant extract having the astringent property, antibacterial property and anti-perspiration activity, or containing placenta extract and AsPMg (magnesium L-ascorbyl phosphate) in addition to the above components. The brown algae extract is prepared from seaweeds such as the sea oak, sea trumpet, wakame seaweed, etc., and the sake lees extract includes the same originated from the deep ocean water. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

The present invention inhibits alkaline phosphatase (hereinafter referred to as ALP) inhibition comprising a sake lees extract (including those derived from deep sea water), rice fermentation liquor, arame, kajime and seaweed (hereinafter referred to as brown algae extract). The present invention relates to cosmetics and deodorant cosmetics that have an activity and / or an anti-nonenal production inhibitory effect.

In recent years, the interest in beauty is extremely high regardless of age or gender, and more and more middle-aged and older people wish to remain refreshing and youthful even in an aging society. On the other hand, middle-aged and elderly people have a peculiar body odor, and the peculiar body odor with a blue odor that can be felt by both men and women from around 40 years old is called so-called aging odor and increases with aging It has been a problem for many people, and the emergence of effective countermeasures has been awaited.

From such a viewpoint, an attempt has been made to develop a revolutionary component that fundamentally reviews the so-called deodorant agent.
At present, there are only a few active ingredients that can claim antiperspirant, antibacterial and deodorant effects, and most of these ingredients only deal with the generated sweat and odor. There was nothing to suppress.

Non-Patent Document 1 discloses Nonenal, in which 9-hexadecenoic acid (hereinafter referred to as 9-HDA), a kind of fatty acid in sebum that increases with aging, is decomposed and produced by lipid peroxides and resident bacteria in the skin. (Aging odor) was found, and in order to cope with the change in body odor due to this aging, it is necessary to prevent the decomposition of 9-HDA in sebum, and the antioxidant suppresses the generation of nonenal. It is disclosed to be effective.

Chapter 4 “Usefulness of Body Care Cosmetics” in Non-Patent Document 2 describes in section 8 “Body odor prevention cosmetics” what body odor is, the mechanism of action of body odor prevention cosmetics and their usefulness, especially antiperspirant ingredients, Methods for evaluating bactericidal and deodorant components and antiperspirant effects are disclosed.

Non-Patent Document 3 discloses an apocrine sweat gland secretion suppression effect by an ALP inhibitory activity of plant extracts such as Altea extract, sage extract, Roman chamomile extract, or urgonum extract as an approach to the mechanism of odor generation.

Patent Document 1 describes a novel cold deodorant cosmetic that can suppress the amount of antiperspirant, disinfectant, and deodorant, is excellent in safety, and can provide a sufficient deodorant effect and an appropriate refreshing feeling over a long period of time. For the purpose of providing, it contains at least one of a cooling sensation component, a cooling sensation substance, an antiperspirant / bactericidal agent / deodorant, and isopropylmethylphenol as a bactericidal agent, and also as an antiperspirant agent A compound containing a chlorohydroxyaluminum component is disclosed.

In Patent Document 2, a deodorant agent and a sputum-glucuronidase inhibitor formed by blending a plant and fungi or an extract thereof selected from Ougon, Gobaishi, Gardenia, Chamomile, Hamamelis and the like without killing resident bacteria on the skin, Since generation of unpleasant body odor can be continuously suppressed, cosmetics having an excellent deodorizing effect and high safety have been disclosed.
As described above, some deodorant preparations containing one or more plant extracts are disclosed, but all these ingredients and liquor extract, brown algae such as rice fermented liquor and arame, No ALP-inhibiting active deodorant cosmetics that have achieved synergistic effects have been found so far.
Fragrance Journal. 27 (9) .42-46 (1999) Usefulness of cosmetics (Pharmaceutical Daily) The 31st Annual Meeting of the Japanese Cosmetic Science Society (Tokyo) JP 2002-80335 A JP 2002-255776 A

The problem to be solved by the present invention is that of an ALP-inhibiting activity deodorant cosmetic that fundamentally suppresses the generation of odor and sweat by using a liquor extract having ALP-inhibiting activity, and an extract comprising brown algae such as rice fermentation broth and arame. It is for the purpose of provision.
Another problem to be solved by the present invention is that brown algal extracts such as sake lees extract and arame have an antioxidant action, and therefore aim at ancillary actions such as stabilization of cosmetic ingredients by their addition.
That is, the placenta extract added as a skin nutrient in the present invention originally contains ALP, and this ALP may sufficiently produce nonenal from HDA, and ascorbic acid (hereinafter referred to as AsA). L-ascorbylmagnesium phosphate (hereinafter referred to as AsPMg) produced for the stabilization of As is also considered to produce AsA by ALP, and in terms of sealing this decomposition, brown algae such as sake lees extract and arame It is noted that the addition is useful.

According to the present invention, the above object is achieved by a deodorant cosmetic composition comprising an ALP inhibitory active composition comprising a sake lees extract and / or brown algae extract containing a rice fermentation broth.
In the present invention, since the ALP inhibitory active composition is used, it is possible to obtain a deodorant cosmetic that fundamentally suppresses the generation of odor and sweat and a deodorant cosmetic that makes use of the antioxidant action.

Further, according to the present invention, the deodorant cosmetic composition according to the present invention has a blending ratio of sake lees extract and brown algae extract containing rice fermented liquid of 1.0: 0. It is achieved by a deodorant cosmetic material characterized by being 0.5 to 1.0.
In the present invention, since the blending ratio of the sake lees extract and brown algae extract containing the rice fermentation liquor is specified, a deodorant cosmetic with better deodorization and the like can be obtained.

Moreover, the said objective is achieved by the deodorant cosmetics characterized by the said deodorant cosmetics containing a nonenal formation prevention component according to this invention.
In the present invention, an excellent deodorant cosmetic can be obtained by preventing the generation of Nonenal which is a causative substance of body odor.

The above object is achieved according to the present invention by a cosmetic characterized in that the cosmetic contains placenta extract and AsPMg.
In the present invention, in a cosmetic containing a placenta extract having ALP activity, it is possible to maintain the stability of other components such as AsPMg by the ALP inhibitory active component.

In addition, according to the present invention, the above-mentioned object is achieved by a deodorant cosmetic material in which the brown algal extract is composed of seaweeds of arame and / or scabbard and / or seaweed.
In the present invention, since the brown algae extract is specified as arame, kajime and wakame, it is possible to obtain a deodorant cosmetic material that fully utilizes the astringent action of arame, kajime and wakame.

Moreover, the said objective is achieved by the deodorant cosmetics characterized by the said sake lees extract containing the thing derived from deep sea water according to this invention.
In the present invention, since the sake lees extract is specified to be derived from deep sea water, a deodorant cosmetic utilizing the contained ALP inhibitory active ingredient and the contained mineral ingredient is obtained.

Moreover, the said objective is achieved by the deodorant cosmetics which said aromatic deodorant cosmetics contain aromatic plant extracts, such as essential oil which has aromaticity, according to this invention.
In the present invention, since it is based on cosmetics containing plant extracts, especially aromatic plant extracts such as aromatic essential oils, an excellent deodorant cosmetic can be obtained in combination with the above-mentioned components such as antiperspirant and astringent. .

The above object is achieved according to the present invention by a deodorant cosmetic characterized in that the deodorant cosmetic comprises a metal component (including a noble metal component) in the deodorant cosmetic component.
In this invention, since the metal component was mix | blended with the deodorant cosmetics, the deodorant cosmetics excellent in antibacterial action are obtained.

According to the present invention, the above object is achieved by a method for producing a deodorant cosmetic comprising an ALP inhibitory active composition comprising a sake lees extract and / or brown algae extract containing a rice fermentation broth.
In this production method, since the ALP inhibitory active composition is used, it is possible to obtain a deodorant cosmetic that suppresses the generation of odor and sweat from the beginning and a deodorant cosmetic that makes use of the antioxidant action.

The object of the present invention is that, according to the present invention, the deodorant cosmetic has a blending ratio of sake lees extract and brown algae extract containing rice fermented liquid of 1.0: 0. This is achieved by a method for producing a deodorant cosmetic, characterized in that it is from 05 to 1.0.
In this production method, since the blending ratio of the sake lees extract and brown algae extract containing the rice fermented liquid is specified, a deodorant cosmetic with better deodorization and the like can be obtained.

Moreover, the said objective is achieved by the manufacturing method of the deodorizing cosmetics characterized by the said deodorizing cosmetics containing a nonenal formation prevention component according to this invention.
In this production method, an excellent deodorant cosmetic can be obtained by preventing the generation of nonenal which is a causative substance of body odor.

According to the present invention, the above object is achieved by a cosmetic production method, wherein the cosmetic comprises placenta extract and AsPMg.
In this production method, it is possible to maintain the stability of other components such as AsPMg due to the ALP inhibitory active component in a cosmetic containing a placenta extract having ALP activity.

Moreover, the said objective is achieved by the manufacturing method of the deodorizing cosmetics which the said brown algae extract consists of seaweed of arame and / or a sword and / or seaweed according to this invention.
In the present production method, the brown algae extract is specified as arame, swordfish or seaweed, and therefore, a deodorant cosmetic that fully utilizes the astringent action of shimeji, swordfish or seaweed can be obtained.

Moreover, the said objective is achieved by the manufacturing method of the deodorant cosmetics characterized by the said sake lees extract containing the thing derived from deep sea water according to this invention. In this production method, since the sake lees extract is specified to be derived from deep sea water, a deodorant cosmetic that makes use of the contained ALP inhibitory active ingredient and the contained mineral ingredient is obtained.

Moreover, the said objective is achieved by the manufacturing method of the deodorizing cosmetics which the said deodorizing cosmetics contain aromatic plant extracts, such as essential oil which has aromaticity, according to this invention.
In this production method, the use of a plant extract, particularly an aromatic plant extract such as an aromatic essential oil, provides a deodorant cosmetic that is excellent in combination with the antiperspirant and astringent components described above. It is done.

According to the present invention, the above-described object is achieved by a method for producing a deodorant cosmetic, wherein the deodorant cosmetic is obtained by blending a metal component (including a noble metal component) with the deodorant cosmetic component. Is done.
In this production method, since the metal component is blended with the deodorant cosmetic, a deodorant cosmetic with an excellent antibacterial action can be obtained.

In the present invention, since the ALP inhibitory active composition is blended, a deodorant cosmetic that is effective for odor, skin sweat odor and antiperspirant can be obtained.
Further, in the present invention, in a cosmetic containing a placenta extract that is considered to contain ALP, it is possible to maintain the stability of other components such as AsPMg by the ALP inhibitory active ingredient.
In addition, since the concentration of various extract components is specified, a deodorant cosmetic with more excellent ALP inhibitory activity can be obtained.
In addition, since various plant extracts are blended, a deodorant cosmetic with excellent antiperspirant action, antibacterial action, astringent action, sebum secretion inhibiting action, anti-inflammatory action, antioxidant action, and odor masking can be obtained.
Furthermore, since the sake lees extract, rice fermented liquor, arame, etc., in which ALP inhibitory activity is observed in the present invention, are blended with known deodorant cosmetics that do not have these inhibitory activities, the deodorant with excellent sustained and stable ingredients Cosmetics can be obtained.
Furthermore, since it comprises a ferulic acid-containing sake lees extract and a phloroglucin-containing alame extract belonging to polyphenols, the oxidative degradation of 9-HDA is suppressed, and the effect of inhibiting the formation of nonenal is observed.

Hereinafter, preferred embodiments of the present invention will be described in detail.
The embodiments described below are preferable specific examples of the present invention, and thus various technically preferable limitations are given. However, the scope of the present invention is particularly limited in the following description. As long as there is no description of the effect, it is not restricted to these aspects.

Below, a body odor is demonstrated.
Body odor is the odor that the metabolites of lower fatty acids bring together when sweat components (proteins, amino acids, lipids, sterols, etc.) secreted to the skin surface are assimilated by the skin resident microorganisms It is recognized. The secretion of sweat, i.e. sweating, is an important phenomenon in terms of physiological function, but may adversely affect the skin. The occurrence of blisters and odors are typical, and it is necessary to prevent them not only from the viewpoint of skin hygiene but also from the cosmetic point of view. In particular, the unpleasant odor of the scent is due to the fact that sweat secreted from apocrine glands present in special sites such as the eccrine glands and the armpits present in almost all skin is decomposed by skin resident microorganisms. As odor components, lower fatty acids such as butyric acid, valeric acid, caproic acid and capric acid and trimethylamine are known.
On the other hand, it has been found that the aging odor is due to Nonenal, which is produced by decomposition and production of 9-HDA, which is one of fatty acids in sebum that increases with aging, by lipid peroxides and resident bacteria in the skin. In order to cope with the change in body odor due to aging, it is necessary to prevent the decomposition of 9-HDA in sebum, and it has been confirmed that antioxidants are effective in suppressing the production of nonenal (Fragrance Journal 27 (9) .42-46 (1999)).
In order to prevent these body odors and aging odors, an antiperspirant component that exhibits antiperspirant action by astringent action, a bactericidal component that reduces odor by reducing the activity of skin resident microorganisms, and a lower cause of odor A deodorizing component that exhibits an effect of eliminating and reducing odors by neutralizing and adsorbing fatty acids has been used for a long time.

In general, antiperspirant components include aluminum hydroxychloride, aluminum chloride, potassium aluminum sulfate (alum), aluminum sulfate, aluminum acetate, allantoin chlorohydroaluminum, aluminum / zirconium chlorohydrate / glycine complex, and zinc p-phenolsulfonate. is there. Regarding the antiperspirant mechanism of these metal compounds, the metal compound applied to the skin forms a metal hydroxide gel in the sweat pores, and the gel accumulates in the sweat pores and the sweat pores are blocked to some extent. It is said that the amount of sweating can be suppressed by this (usefulness of cosmetics; Yakuji Nippo).

In general, the sterilizing component includes triclosan, benzalkonium chloride, benzethonium chloride, chlorhexidine hydrochloride, chlorhexidine gluconate, isopropylmethylphenol, and the like. (Usefulness of cosmetics; Yakuji Nipposha).

Furthermore, in general, deodorant components include plant extracts containing flavonoids such as green tea dry distillation extract, zinc oxide composites, hydroxyapatite, etc., and the deodorant components contain short chain fatty acids that have actually been generated. It is said to be effective in eliminating / reducing odors due to the sum and adsorption action (usefulness of cosmetics; Yakuji Nippo).

The antiperspirant effect evaluation methods include weight measurement method, iodine / starch reaction method, replica method, etc., and the bactericidal effect evaluation methods include staphylococcal count measurement method, bactericidal odor reduction effect measurement method, etc. (Usefulness of cosmetics; Yakuji Nippo).

Below, each component used for this invention is demonstrated. Of these components, plant extracts and rice fermentation broth are all commercially available.
(1) The deep sea water used to obtain the sake lees used in the ALP-inhibiting active deodorant cosmetic composition of the present invention is a layer of surface seawater that has settled. It is seawater rich in minerals.
Specifically, it is also known that deep ocean water contains a larger amount of phosphate ions, silicate ions, nitrate ions, etc., which are generally called nutrient salts, compared to surface water. .
Deep sea water contains many mineral components, so it has a good effect on the human body. For this reason, it has been known to make use of its active ingredients in beauty and health foods and cosmetics. ing.
The sake lees components used in the present invention are sake lees derived from deep ocean water, and are produced during the production of sake such as sake and mirin.
The deep sea water and the deep-sea water-derived sake lees are described in detail in Japanese Patent Application No. 2003-147054 (Japanese Patent Laid-Open No. 2004-346045) related to the applicant's application.
(2) Rice fermented liquid is a liquid obtained by subjecting rice obtained from rice Oryza sativa Linne (Gramineae) to alcoholic fermentation, and contains vitamins B1, B2, amino acids and the like. It has the effect of improving the moisture retention ability of the skin, and has the effect of preventing and roughening the skin.
(3) The brown algae extract is described below.
There are about 20,000 kinds of seaweed in the world, and the seaweed extract extracted from the seaweed contains components such as mucous polysaccharides (polysaccharides), amino acids, minerals, and alginic acid, and has excellent moisturizing effect. And skin regeneration. Among them, a brown algal extract obtained from brown algae such as arame, kajime and wakame contains a polyphenol such as phloroglucin and has a strong antioxidant effect. Furthermore, brown algae extract promotes lipolysis and blood circulation, and promotes metabolism of water and waste products, so it is also incorporated into slimming cosmetics.
(4) Gold colloid is a solution in which gold is micronized into nanometers (10 nanometers = one billionth of a meter) and has antibacterial action.
(5) The sage extract is a plant extract extracted from salvia (sage), which exhibits antibacterial, astringent, and blood circulation promoting effects and prevents skin troubles due to stress and the like.
(6) Altea extract is a plant extract extracted from the roots of mallows and the like, has a high water retention ability, has a moisturizing effect, protects the skin and has an astringent action, and has an action of protecting the mucous membrane. (7) Ougon extract is a plant extract extracted from the roots of Scutella niger and has anti-inflammatory, anti-allergic and astringent effects, and is used for skin tightening, whitening and UV protection.
(8) Roman chamomile extract is a plant extract extracted from the flowers of Roman chamomile, has a strong anti-inflammatory action, and exhibits anti-inflammatory action on skin such as rough skin due to dryness and acne.
(9) Cha extract is a plant extract obtained from tea leaves, contains tannins, amino acids, vitamin C, etc., has an astringent, antioxidant, whitening effect, etc., and also has a function to suppress active oxygen, aging There is also prevention.
(10) Soybean extract is a bio-component made from soybeans, contains female hormones such as isoflavones, keeps moisture for a long time, protects the skin from drying, and also has the same action as female hormones, thus suppressing aging. It is also effective.
(11) Placenta extract has been further improved in the extraction of components from the elucidation and clinical research of water-soluble and fat-soluble components contained in the placenta, and from various vitamins, amino acids, peptides, minerals, cholesterol, enzymes, and sugars. The biologically active substance is analyzed, and the existence of unknown low molecular organic substances is presumed. The effect is wide-ranging, promotes blood circulation and has a metabolic effect, thereby improving the activity of moisturizing cells by improving stains and freckles, etc.Furthermore, peripheral nerve promotion action, cell activation action, active oxygen removal action, Inflammatory action, anti-fatigue action, growth promotion, activation of hematopoietic function, enhanced resistance to bacterial infection, increased milk secretion, autonomic nerve regulating action, skin rejuvenation action, etc.
(12) Asc, which is an active form of AsPMg, accounts for about one-third of the proteins in our body and is said to be involved in the production of collagen, which is the main component of connective tissues such as bone and skin. It is said that it is difficult to maintain a physical condition when it is easily consumed due to drinking, smoking, stress, etc., and it is difficult to maintain the physical condition.
(13) Pyridoxine hydrochloride (water-soluble vitamin B6) is involved in the synthesis and metabolism of amino acids and proteins, and is considered to contain sebum secretion-inhibiting components. It is abundant in spinach and liver, and its deficiency is said to cause stomatitis and glossitis.
(14) Moreover, the plant extract described below shows antibacterial, astringent action or aromaticity.
Hamamelis extract, horse chestnut seed extract (marronnier extract), grape leaf extract, Hypericum perforatum extract, Kizota extract, rosemary extract, birch extract, mallow extract, aloe vera leaf extract

The production process of brown algae extract is described below.
1) Add ethanol to chopped domestic arame and extract at room temperature with occasional stirring for 2 days.
2) Extract at room temperature for several days with occasional stirring.
3) Suction filtration to obtain brown algae extract.
4) Further, the filtrate is concentrated to dryness, the residue is extracted with purified water at 50 ° C. for 1 day, and the extract is concentrated to dryness to obtain an arame extract.

The manufacturing process of the sake lees extract for ALP inhibitory active deodorant cosmetics is shown below.
1) Add purified water to sake and shochu fumigomi and dried shochu using deep sea water.
2) Extract at room temperature for several days.
3) Concentrate by heating in a boiling water bath.
4) Add purified water and perform suction filtration to obtain a sake lees extract.

The rice fermentation liquor charged with deep ocean water used in the present invention is shown below.
It is the liquid manufactured with the manufacturing method defined in the rice fermented liquid of quasi-drug raw material specification 2006 description.

The dosage form of the antiperspirant according to the present invention will be described below.
As general dosage forms of antiperspirant / deodorant cosmetics, there are liquid, powder, stick, aerosol, roll-on, cream, etc. In recent years, many sticks and aerosols have been used.
The deodorant antiperspirant cosmetic and ALP activity inhibitor of the present invention are preparations such as deodorant agents and cosmetics, such as creams, emulsions, lotions, powders, sprays, sticks, aerosols, roll-on types, sheets or coatings, etc. It can be used as a patch.

(Example 1) A beauty cream with excellent stability of additive components was obtained as follows.
Ingredient name Compounding amount (%)
1 Polyoxyethylene sorbitan monolaurate (20E.O.) 1.50
2 Sorbitan sesquioleate 0.75
3 Glyceryl stearate 1.00
4 Behenyl alcohol 2.00
5 Squalane 5.00
6 Tocopherol 0.10
7 Macadamia nut oil 2.00
8 Appropriate amount of purified water
9 Concentrated glycerin 8.00
10 1,3-butylene glycol 6.00
11 Acrylic acid / methacrylic acid copolymer 0.20
12 Purified water 5.00
13 Potassium hydroxide appropriate amount
14 L-ascorbyl magnesium phosphate (AsPMg) 0.50
15 Placenta extract 1.00
16 Sake lees extract 1.00
17 Saitai extract 0.50
18 Water-soluble collagen 0.50
19 Preservative appropriate amount
Total 100.00
-Mix the above ingredients 1-7 and warm to 80 ° C. (A)
-Mix each component 8-10 and heat to 80 ° C. (B)
-Add Phase A to Phase B and uniformly emulsify.
-Stir and cool to 60 ° C and add ingredients 11 and 12 to make uniform.
-Cool to 40 ° C and add ingredients 13 and 14 to make uniform.
-Stop cooling at 35 ° C and add 15-19 to make it even.
・ Place and complete.

(Example 2) By the following, the mist excellent in the antiperspirant effect | action, the skin sweat odor suppression effect, and the habit odor suppression effect was obtained.
Ingredient name Compounding amount (%)
1 Ethanol appropriate amount
2 Appropriate amount of purified water
3 Chlorhydroxyaluminum 0.75
4 Isopropylmethylphenol 0.05
5 Water-soluble placenta extract 0.01
6 Dipropylene glycol 2.80
7 Phenoxyethanol 0.20
8 Pyridoxine hydrochloride 0.03
9 Gold colloid solution 0.03
10 Rose oil 0.01
11 Allantoin 0.01
12 Glycerol mono-2-ethylhexyl ether 0.15
13 Polyoxyethylene sorbitan monooleate (20E.O.) 0.50
14 Black tea extract 0.20
15 1,3-Butylene glycol 0.50
16 Birch extract 0.01
17 Sage extract 0.01
18 Altea extract 0.01
19 Mallow extract 0.01
20 Cha extract (1) 0.05
21 Soybean extract 0.01
22 Brown algae extract 0.10
23 Citric acid 0.01
24 Cyanocobalamin 6.00 (*)
25 Natural vitamin E 80.00 (*)
26 Rosemary Extract 8.00 (*)
27 Camelis extract 0.10 (*)
28 Marronie extract 0.10 (*)
29 Grape leaf extract 0.06 (*)
30 Kizuta Extract 0.05 (*)
31 Water-soluble Arnica extract 0.12 (*)
32 Hypericum extract 0.17 (*)
33 Ogon Extract 5.00 (*)
34 Preservative appropriate amount Note (*) mark is mg / g%

(Example 3) By the following, the cream excellent in the antiperspirant effect | action, the skin sweat odor suppression effect, and the habit odor suppression effect was obtained.
Ingredient name Compounding amount (%)
1 Purified water
2 Ethanol appropriate amount
3 Decamethylcyclopentasiloxane 18.00
4 Isononyl isononanoate 5.00
5 Behenyl alcohol 0.80
6 Sara honey bees 1.00
7 Poly (oxyethylene / oxypropylene)
Methylpolysiloxane copolymer 3.00
8 Methylpolysiloxane / cetylmethylpolysiloxane / poly (oxyethylene / oxypropylene) methylpolysiloxane copolymer 0.80
9 Cross-linked silicone powder (2) 0.50
10 Hydrous silica 1.20
11 1,2-pentanediol 2.50
12 Sodium chloride 0.90
13 1,3-Butylene glycol 6.00
14 Natural vitamin E 0.15
15 Polyoxyethylene hydrogenated castor oil 1.00
16 Colloidal gold 0.03
17 Pyridoxine hydrochloride 0.03
18 Glycerol mono-2-ethylhexyl ether 0.18
19 Water-soluble placenta extract 0.02
20 Black tea extract 0.20
21 Rose oil 0.02
22 Rice fermentation broth 0.10
23 Brown algae extract 0.10
24 Chlorhydroxyaluminum 0.75
25 Isopropylmethylphenol 0.05
26 Rosemary extract 0.01
27 Birch extract 0.01
28 Sage extract 0.01
29 Altea extract 0.01
30 mallow extract 0.01
31 Cha extract (1) 0.05
32 Soybean extract 0.01
33 Cyanocobalamin 0.60 (*)
34 Camelis extract 0.10 (*)
35 Marronnier extract 0.10 (*)
36 Grape leaf extract 0.06 (*)
37 Kizuta Extract 0.05 (*)
38 Water-soluble Arnica extract 0.12 (*)
39 Hypericum extract 0.17 (*)
40 ougon extract 5.00 (*)
41 Preservative Appropriate amount Note (*) is mg / g%

Below, the ALP inhibitory activity measurement result of the sake lees extract and brown algae extract used for the antiperspirant of this invention is shown below. This method is based on phenol liberated from the substrate disodium phenylphosphate by ALP, and was measured by the method listed in the Quasi-drug Raw Material Standard 2006. Test conditions or inhibitory activity are as shown in the table below. Moreover, since it was confirmed that the sake lees extract and the rice fermentation broth have equivalent ALP inhibitory activity, description of the rice fermentation broth is omitted.
[Table 1] Measurement of ALP inhibitory activity of sake lees extract and brown algae extract; experimental conditions
Reagent (mL) / tube name 1 2 3 4 5 6 7
Substrate buffer (pH 10.10) 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL
ALP (standard product) 0.1% 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL
Sake lees extract-1.0mL 0.1mL--1.0mL 0.1mL
Brown algae extract---1.0mL 0.1mL 1.0mL 0.1mL
Color reagent (pH6.22) 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL
[Table 2] Evaluation of ALP inhibitory activity
Test tube name 1 2 3 4 5 6 7
Inhibitory activity-++++++++++++
(Note)-: No activity, +: 20% inhibition, ++: 40% inhibition, ++++: inhibition of 50% or more

Below, the synergistic effect measurement result of the ALP inhibitory activity of the sake lees extract by the various plant extracts used for the antiperspirant of this invention is shown below.
[Table 3] Measurement of synergistic effect of ALP inhibitory activity of sake lees extract by various plant extracts; Experimental condition: Reagent (mL) /
Test tube name 1 2 3 4 5 6 7 8 9 10
Substrate buffer 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL
(pH10.10)
ALP (standard product) 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL
0.1%
Sake lees extract 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 0.1mL 0.1mL 0.1mL 0.1mL 0.1mL
Roman chamomile extract 0.1mL 0.1mL
Ogon Extract 0.1mL 0.1mL
Altea extract 0.1mL 0.1mL
Sage extract 0.1mL 0.1mL
Color reagent 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL
(pH 6.22)
[Table 4] Evaluation of synergistic effect of ALP inhibitory activity
Test tube name 1 2 3 4 5 6 7 8 9 10
Inhibitory activity-++ ++ ++ +-++ ++ ++
(Note) Synergistic effect with sake lees extract:-: Standard value, +: 10% increase, ++: 20% or more increase

Below, the synergistic effect measurement result of the ALP inhibitory activity of the brown algae extract by the various plant extracts used for the antiperspirant of this invention is shown below.
[Table 5] Measurement of synergistic effect of ALP inhibitory activity of brown algae extract by various plant extracts; Experimental conditions: Reagent (mL) /
Test tube name 1 2 3 4 5 6 7 8 9 10
Substrate buffer 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL 5.0 mL
(pH10.10)
ALP (standard product) 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL
0.1%
Brown algae extract 1.0mL 1.0mL 1.0mL 1.0mL 1.0mL 0.1mL 0.1mL 0.1mL 0.1mL 0.1mL
Roman chamomile extract 0.1mL 0.1mL
Ogon Extract 0.1mL 0.1mL
Altea extract 0.1mL 0.1mL
Sage extract 0.1mL 0.1mL
Color reagent 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL 5.0mL
(pH 6.22)
[Table 6] Evaluation of synergistic effect of ALP inhibitory activity
Test tube name 1 2 3 4 5 6 7 8 9 10
Inhibitory activity-++ ++ ++ +-++ ++ ++
(Note) Synergistic effect with brown algae extract:-: Reference value, +: 10% increase, ++: 20% or more increase [Measurement method]

[Use test 1]
・ Antiperspirant action-sweat volume measurement (30 subjects each male and female)
Subjects: 30 healthy males and females aged 18 to 65 who do not observe any abnormalities such as inflammation in the axilla (1) Initialization of the axillas Suspensions were completely discontinued and axillary cleaning agents and cleaning methods were designated. Thereafter, the normal amount of sweating (20 minutes) was measured in a room set and maintained at a temperature of 37 to 38 ° C. and a relative temperature of 35 to 40%. The subjects were blindly coated with Examples 1 and 2 and Comparative Examples 1 and 2 on the left and right heels for 4 days from the day after the normal sweating measurement. Before each application of the examples and comparative examples, the test subject was washed on both sides of the test subject. On the first day, only the examples and comparative examples were applied, and the second and third days. After the application of Examples and Comparative Examples, the amount of sweating is measured. On the fourth day, only the application of Examples and Comparative Examples is performed, and on the fifth day, only the amount of sweating is measured. For measuring the amount of perspiration, a water absorbing pad was used, and the antiperspirant effect was evaluated from its weight.
Sweating volume (number of subjects)
Significant decrease Decrease Decrease slightly No change <br/> Comparative example 1 (30 persons) 2 6 11 11
Example 1 (30 people) 12 7 8 3
Sweating volume (number of subjects)
Significant decrease Decrease Decrease slightly No change <br/> Comparative example 2 (30 people) 6 5 12 10
Example 2 (30 people) 10 9 8 3

[Use test 2]
・ Measurement of lower fatty acid content in sweat (GC / MS)
The water-absorbent pad obtained in the above usage test 1 was extracted with diethyl ether using a Soxhlet extraction tube to obtain an axillary extract. The obtained axilla extract was analyzed for lower fatty acids using gas chromatography (GC / MS), and the concentration in each sweat was measured. The measured value was used as an index for reducing the odor.
Lower fatty acid concentration in sweat (number of subjects)
Significantly lowered slightly reduced without loss change <br/> Comparative Example 1 (30 people) 3 8 12 7
Example 1 (30 people) 13 8 8 1
Lower fatty acid concentration in sweat (number of subjects)
Notably reduced Decrease slightly less No change <br/> Comparative example 2 (30 people) 2 8 11 10
Example 2 (30 people) 11 10 8 1

Although the present invention is configured as described above, it is also possible to blend one or more components of sage extract, altea extract, and urgonum extract with sake lees extract and brown algae extract containing rice fermented liquid. is there.
In this case, since the sake lees extract and brown algae extract containing the rice fermented liquid are blended with one or more components of sage extract, altea extract, and urgonum extract, the deodorant has excellent astringent action and antiperspirant action. Cosmetics can be obtained.

The present invention is configured as described above, and the deodorant cosmetic is a brown algae extract, sage extract, altea extract, hornon extract, tea extract, hamamelis extract, horse chestnut seed extract (marronnier extract), grape leaf extract, It is also possible to mix two or more of the following components: Hypericum perforatum extract, Kizuta extract, Rosemary extract, birch extract, mallow extract, and aloe vera leaf extract.
In this case, since the deodorant cosmetic ingredients are more specifically specified, the action of these ingredients is combined, and the deodorant has excellent synergistic effects such as anti-inflammatory, antibacterial, astringent, moisturizing and blood circulation promoting actions. Cosmetics are obtained.

Although this invention is comprised as mentioned above, the metal component used for the said deodorant cosmetics can also be a gold colloid.
In this case, since the metal component used in the deodorant cosmetic is specified as the gold colloid, a deodorant cosmetic with more excellent antibacterial action can be obtained.

The present invention is configured as described above, and the metal component is further made of Camelis extract, horse chestnut seed extract (marronnier extract), grape leaf extract, Hypericum perforatum extract, Kizota extract, rosemary extract, birch extract, mallow It is also possible to blend one or more components of the extract and aloe vera leaf extract.
In this case, in addition to the metal component used in the deodorant cosmetic, a plant extract having an antibacterial action is blended, so that a deodorant cosmetic with a better antibacterial action can be obtained.

Although the present invention is configured as described above, still further, according to the present invention, two kinds of sake lees extract, brown algae extract, sage extract, altea extract, ougon extract, roman chamomile extract and colloidal gold containing rice fermentation broth It is also possible to mix the above components.
In this case, since the deodorant cosmetic ingredients were specifically identified, the action of these ingredients combined, the deodorant makeup with excellent synergistic effects such as anti-inflammatory, antibacterial, astringent, moisturizing and blood circulation promoting effects. A fee is obtained.
In addition, when specifying each compounding quantity of these components concretely, an effect is still increased.

The present invention is configured as described above, but still contains a rice fermented liquor extract, brown algae extract, placenta extract, sage extract, altea extract, ougon extract, roman chamomile extract, colloidal gold, hamamelis extract, horse chestnut seed Two or more of the following components are included: extract (marronnier extract), grape leaf extract, Hypericum perforatum extract, Kizuta extract, rosemary extract, birch extract, mallow extract, aloe vera leaf extract, soybean extract, pyridoxine hydrochloride, tea extract, vitamin B12 It can also be blended.
In this case, since the deodorant cosmetic ingredients have been specified more specifically, the action of these ingredients is combined to eliminate the synergistic effects such as anti-inflammatory, antibacterial, astringent, moisturizing and blood circulation promoting actions. An odor cosmetic is obtained.
In addition, when specifying each compounding quantity of these components concretely, an effect is still increased.

Although this invention is comprised as mentioned above, it is also possible to set the compounding ratio of the liquor extract containing a rice fermented liquor, a brown alga extract, and the said plant extract to 1.0: 0.0004-0.4. .
In this case, since the blending ratio of sake lees extract, brown algae extract and plant extract containing rice fermented liquid of deodorant cosmetic ingredients was specifically specified, the action of these ingredients combined, the astringent action and the control. It is possible to obtain a deodorant cosmetic with a better sweating action.

Although the production method of the present invention is configured as described above, the production method in which the blending ratio of the sake lees extract, brown algae extract and the plant extract containing rice fermented liquid is 1.0: 0.0004 to 0.4. It is also possible.
In the case of this production method, since the blending ratio of sake lees extract, brown algae extract and plant extract containing rice fermented liquid of deodorant cosmetic ingredients was specifically specified, the action of these ingredients combined with the convergence A deodorant cosmetic with better action and antiperspirant action can be obtained.

Claims (16)

A deodorant cosmetic comprising an alkaline phosphatase (ALP) inhibitory active composition comprising a sake lees extract and / or brown algae extract containing a rice fermentation broth. 2. The deodorant cosmetic according to claim 1, wherein the deodorant cosmetic has a ratio of liquor extract and brown algae extract containing a rice fermentation broth of 1.0: 0.05 to 1.0. The deodorant cosmetic according to claim 1 or 2, wherein the deodorant cosmetic contains a nonenal formation-preventing component. The cosmetic comprises a placenta extract and L-ascorbyl magnesium phosphate (AsPMg). The deodorant cosmetic according to any one of claims 1 to 3, wherein the brown algae extract is composed of seaweed of arame and / or scabbard and / or seaweed. The deodorant cosmetic according to any one of claims 1 to 3, wherein the sake lees extract contains one derived from deep sea water. 6. The deodorant cosmetic composition according to claim 1, wherein the deodorant cosmetic is a plant extract having aromatic, astringent, antibacterial, and antiperspirant properties including an aromatic plant-derived extract such as an aromatic essential oil. Deodorant cosmetic according to any one of the above. The deodorant cosmetic according to any one of claims 1 to 3 or 5 to 7, wherein a metal component (including a noble metal component) is blended with the deodorant cosmetic component. A method for producing a deodorant cosmetic comprising an ALP inhibitory active composition comprising a sake lees extract and / or brown algae extract containing a rice fermentation broth. The said manufacturing method is a manufacturing method of the deodorizing cosmetics of Claim 9 whose compounding ratio of the sake lees extract containing rice fermentation liquor and a brown algae extract is 1.0: 0.05-1.0. The method for producing a deodorant cosmetic according to claim 9 or 10, wherein the production method includes a nonenal formation-preventing component. A method for producing a cosmetic comprising a placenta extract and AsPMg. The said manufacturing method is a manufacturing method of the deodorizing cosmetics of Claims 9-11 in which the said brown-algae extract consists of seaweed of an arame and / or a sword and / or a seaweed. The method for producing a deodorant cosmetic according to any one of claims 9 to 10, wherein the production method comprises the sake lees extract derived from deep sea water. The said manufacturing method is based on the plant extract which has aromatic, astringent, antibacterial, and antiperspirant containing aromatic plant origin extracts, such as an essential oil which has aromaticity, The 9-11 or 13-14 characterized by the above-mentioned. The manufacturing method of the deodorizing cosmetics in any one. The said manufacturing method mix | blends a metal component (a noble metal component is included) with the said deodorant cosmetics component, The manufacture of the deodorant cosmetics in any one of Claims 9-11 or 13-15 characterized by the above-mentioned. Method.