JP2005187474A - Improved scented cosmetic - Google Patents

Improved scented cosmetic Download PDF

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JP2005187474A
JP2005187474A JP2004382301A JP2004382301A JP2005187474A JP 2005187474 A JP2005187474 A JP 2005187474A JP 2004382301 A JP2004382301 A JP 2004382301A JP 2004382301 A JP2004382301 A JP 2004382301A JP 2005187474 A JP2005187474 A JP 2005187474A
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hair
amygdalin
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Takashi Kodera
隆 小寺
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a scented cosmetic which imparts preservation/amelioration of physiological function of the skin and hair by expressing an anti-oxidation action, skin conditioning action, accelerating action for wound healing, antibacterial/anti-mold action, cleaning action, deodorization/odor elimination, etc., in application to the skin and hair, and as a result preventing senile decay, degeneration, mutation of the skin and hair, and preventing/treating various troubles/lesions such as injury, melasma, rough skin, wrinkle, senile plaque, and gray hair, alopecia, and effective for keeping the skin, etc., in health. <P>SOLUTION: The invention relates to the scented cosmetic excellent in functionality comprises amygdalin or a plant extract oil or an extract containing amygdalin such as amygdule, persicae semen, loquat seed, Prunus mume seed, etc. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

本発明は、アミグダリン又は例えば杏仁、桃仁、枇杷の葉や種子などのアミグダリンを含有する植物の抽出液若しくは抽出物を配合してなる、機能性の香粧料・化粧料(以下“香粧料”と総称する)に係わる。かかる香粧料は、皮膚及び毛髪に適用した場合活性酸素消去作用、抗酸化作用、創傷治癒促進作用、抗菌・抗黴作用、防臭・消臭作用などにより皮膚及び毛髪の生理機能の維持・改善ももたらし、その結果特に皮膚及び毛髪の老化、退化や変異を防止すると共にしみ、肌荒れ、しわや老人斑及び白髪、脱毛など皮膚及び毛髪の種々の障害・病変を予防・治癒して健常に維持するのに有効である。  The present invention relates to functional cosmetics / cosmetics (hereinafter referred to as “cosmetics”, which are formulated with amygdalin or an extract or extract of a plant containing amygdalin such as apricot kernel, peach seed, persimmon leaves and seeds. "Collectively"). Such cosmetics, when applied to skin and hair, maintain and improve physiological functions of skin and hair by eliminating active oxygen, antioxidant, wound healing, antibacterial / anti-wrinkle, deodorant / deodorant, etc. As a result, especially skin and hair aging, degeneration and mutation are prevented, and various disorders and lesions of skin and hair such as spots, rough skin, wrinkles, senile plaques, gray hair, hair loss, etc. are prevented and cured to maintain a healthy state. It is effective to do.

皮膚は、人体で最大の器官であり、外部の損傷刺激、水分損失、有害因子侵入を防ぐバリアーとしてまた体温調節を行って体内の恒常性を維持し、同時に経皮呼吸と経皮排泄器官としてまた感覚器官として機能する。また頭髪は、皮脂腺及び血管・神経系とともに皮膚の付属器官を構成し、従って同様に保護・防御器官として機能するものであり、毛包内の毛乳頭部において角化細胞と色素細胞とにより形成されるが、毛周期により成長と脱毛を繰り返し、健常な状態では、50乃至70本/日程度脱毛しその後新たな毛髪の成長により一定の頭髪量が保持される。毛髪は、皮膚と同様に硬タンパク質であるケラチンから構成されているが、そのアミノ酸組成が異なり、架橋結合であるシスチン含量が16乃至18%と多いのが特徴である。  The skin is the largest organ in the human body, as a barrier to prevent external damage irritation, water loss, and harmful factor invasion, and to maintain homeostasis by regulating body temperature, and at the same time as percutaneous breathing and transcutaneous excretion organs It also functions as a sensory organ. The hair, together with the sebaceous glands and the blood vessels / nervous system, constitutes the appendage of the skin and thus functions as a protective and protective organ as well, and is formed by keratinocytes and pigment cells in the dermal papilla in the hair follicle. However, growth and hair removal are repeated according to the hair cycle, and in a healthy state, hair is removed at a rate of about 50 to 70 hairs / day, and then a constant amount of hair is maintained by the growth of new hair. Hair is composed of keratin, which is a hard protein like skin, but its amino acid composition is different and the content of cystine, which is a cross-linked bond, is as high as 16 to 18%.

ヒトの皮膚及び頭髪は、紫外線、精神的ストレスや火傷、打撲など物理的、化学的ストレスによる外的傷害に加えて、加齢が原因となるしみ、シワや白髪、過度の脱毛などの障害変化を受けるほか、免疫機能の異常によるアトピー性皮膚炎、イボ、腫瘍、悪性黒色腫、病的脱毛症などの病的症状を発症しまた植物や昆虫による刺傷を受け易く、結果的に皮膚や毛髪の本来の生理学的機能が損なわれ、最終的には身体の恒常性維持機能が損なわれる結果、種々の障害、病変、疾患が生じる。  In human skin and hair, in addition to external injuries caused by physical and chemical stresses such as ultraviolet rays, mental stress, burns, and bruises, aging-related stains, wrinkles, white hair, excessive hair loss, etc. In addition, it develops pathological symptoms such as atopic dermatitis, warts, tumors, malignant melanoma, pathological alopecia due to abnormal immune function and is susceptible to stings from plants and insects, resulting in skin and hair As a result, the body's original physiological function is impaired, and eventually, the body's homeostatic function is impaired, resulting in various disorders, lesions and diseases.

上記した如き障害、病変や疾患の他に、皮膚や毛髪から発散する臭気、所謂体臭が問題になる場合が少なくない。体臭は、人種、性、年齢などにより特有の匂いを伴なうもので、専ら皮膚及び毛髪に広く分布する汗腺、特に特定部位に分布するアポクリン腺及び皮脂腺から分泌される汗及び中性脂肪など皮脂が、皮膚及び毛髪に生育するアクネ菌、酵母など常在微生物によって分解されて生じた飽和又は不飽和の低級や高級脂肪酸群、またアルデヒドやラクトン類やアンドロステノイド類が原因となって生じるとされている。また頭皮、額などに多い皮脂腺は、中性脂肪、コレステロールなど脂質を含む皮脂を分泌するが、酵母、アクネ菌など常在微生物により短鎖脂肪酸、高級脂肪酸、アルデヒド、ラクトン類に分解され、臭気の原因となる。また人体に密着した下着や靴下は、特に高温、多湿となる春から秋にかけてはこれら常在微生物の格好の培養基に変じ、不快な汗臭、中でもアポクリン腺による腋臭並びにエクリン腺分泌物による角質の分解に起因する足臭が、深刻な問題となっている。  In addition to the above-mentioned obstacles, lesions and diseases, odors emanating from the skin and hair, so-called body odors, often become a problem. Body odor has a specific odor depending on race, sex, age, etc., and sweat glands widely distributed in skin and hair, especially sweat and neutral fat secreted from apocrine glands and sebaceous glands distributed in specific areas Sebum is caused by saturated or unsaturated lower and higher fatty acid groups, and aldehydes, lactones and androstenoids, which are produced by degradation by resident microorganisms such as acne and yeast that grow on the skin and hair. It is supposed to occur. Sebaceous glands, which are often found on the scalp and forehead, secrete sebum containing lipids such as neutral fat and cholesterol, but they are decomposed into short-chain fatty acids, higher fatty acids, aldehydes, and lactones by resident microorganisms such as yeast and acne bacteria, resulting in odors. Cause. In addition, underwear and socks that are in close contact with the human body have changed into a suitable culture medium for these resident microorganisms, especially in the high temperature and humidity from spring to autumn, and unpleasant sweat odor, especially odor due to apocrine glands and keratin due to eccrine gland secretions. Foot odor due to decomposition is a serious problem.

腋臭、汗臭や発汗などの体臭を予防し且つ防止するために使用される制汗・デオドラント製品は、塩化アルミニウム、酸化亜鉛などの発汗抑制成分及び四級アンモニウム塩、塩素化フェノールなどの公知の静菌・消毒剤とが配合されている。しかしながら、これら従来汎用の発汗抑制成分は、その正確な発刊抑制機構は未解明であり、発汗抑制効果は充分とはいえないし、人体に対する毒性の点も問題がある。また消臭成分として使用される消毒・静菌剤も、抗菌活性スペクトルは広く而も皮膚刺激性など人体に対する毒性が低く、無臭であるとされているものの、一方では特にタンパク質、脂質など有機物やミネラル成分の共存下では抗菌効果が大幅に減殺されたりまた微生物による耐性獲得が容易であり、その結果防臭・消臭効果は充分ではないばかりでなく、持続性もほとんど無く寧ろ適用後短時間で異臭を発生するという問題を孕む。また塩素系化合物の場合は、毒性はもとより環境汚染の原因になり問題が多い。従って、上記成分を配合して成る従来公知の市販制汗・防臭剤は、効果・効能、特に持続効果、使用感など多くの点で欠点があり、到底満足出来るものではない。  Antiperspirant and deodorant products used to prevent and prevent body odors such as hazy odor, sweat odor and perspiration are known antiperspirant components such as aluminum chloride and zinc oxide, and quaternary ammonium salts and chlorinated phenols. Contains bacteriostatic and disinfectant. However, these conventional general-purpose antiperspirant components have an unclear elucidation of the exact mechanism for publishing them, and the antiperspirant effect is not sufficient, and there is a problem in toxicity to the human body. In addition, disinfectants and bacteriostatic agents used as deodorant ingredients have a broad antibacterial activity spectrum and low toxicity to the human body, such as skin irritation, and are considered odorless. In the presence of mineral components, the antibacterial effect is greatly diminished and it is easy to acquire resistance by microorganisms. As a result, not only is the deodorizing and deodorizing effect not sufficient, but there is little persistence, rather than a short time after application We apologize for the problem of generating off-flavors. Chlorine compounds are not only toxic but also cause environmental pollution and have many problems. Therefore, the conventionally known commercially available antiperspirant / deodorant containing the above-mentioned components has drawbacks in many respects such as effects and efficacy, in particular, long-lasting effect and feeling of use, and is not satisfactory.

複雑で重要な皮膚及び毛髪の生理機能を健常に維持するために、皮膚創傷治療剤、汚れを除去する洗浄剤、口臭・体臭の消去・予防のためのデオドラント剤のほか保湿、油分補給などの整肌や皮膚保護などの香粧料、またコラーゲン合成促進、抗酸化、紫外線保護、また養毛や育毛を目的とした生理学的製剤などの基礎化粧品、また種々のスキンケア用及びヘアケア用製品・香粧料が販売されている。しかしながら、いずれも単一機能が付与されているだけで、上記したような皮膚及び毛髪に伴なう種々の障害・病変や悪臭を網羅的に改善する複合機能を有する製品は市販されたことは全くない。性能・効果やその持続性及び皮膚刺激性など安全性が改善された、多機能型のスキンケア及びヘアケア製品の開発に対する要望が高い。  In order to maintain healthy physiological functions of complex and important skin and hair, such as skin wound treatment agent, cleaning agent for removing dirt, deodorant agent for elimination and prevention of bad breath and body odor, moisturizing, oil replenishment, etc. Cosmetics such as skin conditioning and skin protection, basic cosmetics such as physiological preparations for collagen synthesis promotion, antioxidant, UV protection, hair restoration and hair growth, and various skin care and hair care products and incense Cosmetics are on sale. However, all of them have been provided with a single function, and a product having a composite function that comprehensively improves various disorders / lesions and odors associated with the skin and hair as described above has not been commercially available. Not at all. There is a strong demand for the development of multifunctional skin care and hair care products with improved safety such as performance / effect, durability and skin irritation.

発明が解決する課題Problems to be solved by the invention

本発明の課題は、皮膚及び毛髪を損傷・病変、老化、及び物理化学的ストレスから保護し、皮膚及び毛髪の生理機能を健常に維持し更には向上させる、改善された香粧料を提供することである。  An object of the present invention is to provide an improved cosmetic that protects skin and hair from damage / lesion, aging, and physicochemical stress, and maintains and further enhances the physiological function of skin and hair. That is.

課題を解決するための手段Means for solving the problem

本発明者は、上記課題を解決するため種々検討を行なった結果アミグダリン又はアミグダリン含有植物の抽出物が抗酸化作用、整肌作用、創傷治癒促進作用、抗菌・抗黴作用、清浄化作用、防臭・消臭作用などを有することを見出し、さらに検討を続けてこれを香粧料に配合することによって上記課題を解決出来ることを見出した。即ち、本発明は、アミグダリン又はアミグダリン含有植物の抽出物を配合してなる香粧料に係わる。  As a result of various studies to solve the above problems, the present inventor has found that amygdalin or an extract of an amygdalin-containing plant has an antioxidant action, skin conditioning action, wound healing promoting action, antibacterial / anti-wrinkle action, cleaning action, deodorization action -It discovered that it had a deodorizing effect etc., and also discovered that the said subject can be solved by continuing further examination and mix | blending this with cosmetics. That is, this invention relates to the cosmetics formed by mix | blending the extract of amygdalin or an amygdalin containing plant.

アミグダリンは、化学名が[6−O−β−D−グルコピラノシル−β−D−グルコピラノシル]オキシ]ベンゼンアセトニトリル([6−O−β−D−glucopyranosyl−β−D−glucopyranosyl]oxy)benzeneacetonitrile)又はD−マンデロニトリル−β−D−グルコシド−6−β−D−グルコシドであり、β−1,6結合した2モルのグルコースが、更にベンゾシアンヒドリンにβ−グルコシド結合した配糖体である。融点は、三水和物が220℃、無水物が200℃で、水に易溶、アルコールに難溶であり、飽和水溶液のpHはほぼ7までである。本出願人の知るかぎり、アミグダリンが、外用・局所投与した場合特定の薬理効果を発揮することは報告されてたことはない。  Amygdalin has the chemical name [6-O-β-D-glucopyranosyl-β-D-glucopyranosyl] oxy] benzeneacetonitrile ([6-O-β-D-glucopyranosyl-β-D-glucopyranosyl] oxy) benzeneacetonitile) or D-mandelonitrile-β-D-glucoside-6-β-D-glucoside, which is a glycoside in which 2 moles of β-1,6-linked glucose is further linked to benzocyanohydrin by β-glucoside. is there. The melting point is 220 ° C. for trihydrate and 200 ° C. for anhydride, it is easily soluble in water and hardly soluble in alcohol, and the pH of the saturated aqueous solution is up to about 7. As far as the applicant knows, it has never been reported that amygdalin exerts a specific pharmacological effect when applied externally or locally.

またアミグダリンを比較的多量に含有する杏、桃や枇杷の種子、梅の種子仁又は葉についても、杏仁や桃仁が、古くから鎮咳・去痰剤として使用されている以外に、格別の用途は知られておらずまた外用・局所投与した事例も知られていない。  As for apricots, peaches and persimmon seeds, and plum seeds or leaves containing a relatively large amount of amygdalin, aside from the fact that apricots and persimmons have long been used as antitussives and expectorants, there are no known special uses. There are no known cases of topical or topical administration.

アミグダリンは、上記した果実の種子以外にもせり、フキ、竹の子などの野菜類また玄米、ヒエ、アワ、ソバ、小豆、大豆などの穀類にも極微量ながら含有されることが判っている。アミグダリンは、例えばエムルシンなどのβ−グルコシダーゼの作用を受けて構成成分化合物である、一モルのマンデロニトリルとニモルのグルコースに変換され、マンデロニトリルは、ヒドロキシニトリルリアーゼ(脱離酵素)により有毒なベンズアルデヒドとシアン化水素に分解される。β−グルコシダーゼは、細菌類、菌類、原生動物に広く認められるが、一方ヒトを含む哺乳動物などについては、腸内において摂取したデンプンなど、α−グルコシド結合を分解する数種類のα−グルコシダーゼが見出されるのに対して、セルロースや配糖体のアグリコンとグリコンとの間に見られるβ−グルコシド結合を分解するβ−グルコシダーゼは、寄生する微生物由来以外は、肝臓や脾臓において僅かに存在するに過ぎないとされている。従って、β−グルコシダーゼを相対的に多く有する細菌、カビなどの微生物に対しては、アミグダリンを散布、噴霧などにより適用した場合に分泌・存在するβ−グルコシダーゼ量に応じて有毒物質が生成され、その結果限定的で且つ特異的な殺微生物作用を発揮するものと考えられる。  Amygdalin is known to be contained in trace amounts in vegetables such as Japanese cypress, bamboo shoots, and grains such as brown rice, mackerel, millet, buckwheat, buckwheat and soybeans in addition to the fruit seeds described above. Amygdalin is converted into a component compound, one mole of mandelonitrile and two moles of glucose under the action of β-glucosidase such as emulsine. Mandelonitrile is toxic by hydroxynitrile lyase (elimination enzyme) It is decomposed into benzaldehyde and hydrogen cyanide. β-Glucosidase is widely recognized in bacteria, fungi, and protozoa. On the other hand, in mammals including humans, several types of α-glucosidases that break down α-glucoside bonds, such as starch ingested in the intestine, have been found. In contrast, β-glucosidase that breaks down the β-glucoside bond found between cellulose and glycoside aglycones and glycones is only slightly present in the liver and spleen, except for parasitic microorganisms. It is said that there is no. Therefore, for microorganisms such as bacteria and molds that have a relatively large amount of β-glucosidase, toxic substances are produced according to the amount of β-glucosidase secreted and present when applied by spraying or spraying amygdalin, As a result, it is considered that a limited and specific microbicidal action is exhibited.

アミグダリンは、通常は上記した杏仁、桃仁など石果類の種子から水若しくは熱水又はエタノール水溶液などのアルコール性水溶液によって抽出され、精製単離することが出来るし、また試薬として市販されている。本発明においては、かかる石果類の種子を熱水又はアルコール性水溶液で抽出して得られる抽出液をそのまま用い得るのが好ましい。  Amygdalin is usually extracted from the above-mentioned stone seeds such as apricot and peach seeds with water, hot water or an alcoholic aqueous solution such as an ethanol aqueous solution, purified and isolated, and is commercially available as a reagent. In the present invention, it is preferable that an extract obtained by extracting the seeds of such stone fruits with hot water or an alcoholic aqueous solution can be used as it is.

発明の効果The invention's effect

アミグダリンは上記したように、天然に存在する配糖体の一種であり、植物色素であるアントシアニン、フラボン類、ヘスペリジン、ケルセチン配糖体、サポニン類などフラボノイド類も同様の配糖体であることから、ファイトケミカルとしての多様な生理作用、例えば抗酸化作用、抗菌・抗黴・抗ウイルス作用などを有していることは明らかであり、また生姜、ウコンなどに含まれるファイトケミカルスと相乗効果を発揮することが期待できる。従って、皮膚や髪に適量を外用した場合、整肌、養毛、抗菌・抗黴、清浄化、消臭・防臭などの好ましい生理学的効果が得られ、皮膚及び毛髪の生理機能の維持・改善をもたらし、その結果皮膚及び毛髪に対する障害・病変の改善・治癒促進が可能でありまた老化、退化及び変異を防止出来る。したがって、肌荒れ、シワ、シミの発生また白髪や病的脱毛に対する予防・治癒効果を発揮し、また腋臭、加齢臭などの体臭に対して消臭・防臭効果を呈することが出来る。  As described above, amygdalin is a kind of naturally occurring glycoside, and flavonoids such as anthocyanins, flavones, hesperidin, quercetin glycosides, and saponins, which are plant pigments, are similar glycosides. It is clear that it has various physiological functions as phytochemicals, such as antioxidant, antibacterial, antifungal and antiviral effects, and also exhibits synergistic effects with phytochemicals contained in ginger, turmeric, etc. Can be expected to do. Therefore, when an appropriate amount is applied externally to the skin and hair, favorable physiological effects such as skin conditioning, hair restoration, antibacterial / anti-wrinkle, cleaning, deodorization / deodorization, etc. are obtained, and the physiological function of the skin and hair is maintained / improved. As a result, it is possible to improve the skin / hair damage / lesion, promote healing, and prevent aging, degeneration and mutation. Accordingly, it can prevent and heal skin roughening, wrinkles and spots, white hair and pathological hair loss, and can exhibit a deodorizing and deodorizing effect against body odor such as scent and aging odor.

即ち、本発明は、アミグダリン又はアミグダリン含有植物からの抽出液若しくは抽出物を有効成分として含有して成る、整肌、養毛、清浄化、殺菌、消臭・防臭、外傷治癒促進、白髪・脱毛の防止及び治癒などの種々の生理学的活性において優れた機能性香粧料に係わる。なお、従来アミグダリン又はアミグダリン含有植物からの抽出液若しくは抽出物を配合した香粧料は知られていないし、かかる香粧料が、整肌、養毛、清浄化、抗菌・抗黴、消臭・防臭、白髪・脱毛などの予防・治癒活性など皮膚及び毛髪に対して好ましい生理学的活性を発揮することは全く知られていない。  That is, the present invention comprises amygdalin or an extract or extract from amygdalin-containing plant as an active ingredient, skin conditioning, hair nourishment, cleaning, disinfection, deodorization / deodorization, promotion of wound healing, gray hair / hair removal The present invention relates to functional cosmetics that are excellent in various physiological activities such as prevention and healing. Conventionally, there is no known cosmetic containing amygdalin or an extract or extract from an amygdalin-containing plant, and such cosmetics are suitable for skin conditioning, hair nourishing, cleaning, antibacterial / anti-wrinkle, deodorant / It has not been known at all that it exerts favorable physiological activities on skin and hair such as deodorization, prevention and healing activities such as white hair and hair loss.

本発明において使用される有効成分としては、アミグダリンそのもののほか、アミグダリンを含有する植物の抽出液若しくは抽出物であれば、特に有害成分を含まない限り如何なるものでもよい。後者としては、例えば、杏仁、桃仁、梅の種子仁、枇杷の種子や葉など、アミグダリンを含む植物の葉や種子の抽出液及び抽出物が挙げられる。  The active ingredient used in the present invention is not limited to amygdalin itself, but may be any as long as it does not contain harmful ingredients as long as it is a plant extract or extract containing amygdalin. Examples of the latter include leaves and seed extracts and extracts of plants containing amygdalin, such as apricot kernels, peach seeds, plum seed seeds, and persimmon seeds and leaves.

アミグダリンは、試薬として市販されており、かかる市販品をそのまま使用してもよく、必要に応じて水性エタノールなどに加温しつつ攪拌して溶解させて無色透明溶液として香粧料に配合使用することも出来る。その場合アミグダリン単体として最終香粧料全体に対する配合割合は、0.1乃至20.0重量%、好ましくは0.2乃至10.0重量%また最も好ましくは0.5乃至5.0重量%である。  Amygdalin is commercially available as a reagent, and such a commercially available product may be used as it is, and if necessary, it is dissolved by stirring with heating in aqueous ethanol or the like, and used in cosmetics as a colorless transparent solution. You can also In that case, the mixing ratio of amygdalin alone to the final cosmetic is 0.1 to 20.0% by weight, preferably 0.2 to 10.0% by weight, and most preferably 0.5 to 5.0% by weight. is there.

アミグダリン含有植物からの抽出は、例えばアミグダリン含有植物の葉、果実、種子、茎などを水又は水性アルコール、例えば20乃至80重量%濃度のエタノールやイソプロパノールの水性溶液で抽出して得られるものであり、具体的には、桃仁、杏仁、枇杷の葉又はその種子、梅の種子仁など、アミグダリンを含有する植物並びにその水や水性アルコール溶液による抽出液及び抽出物が例示される。これら抽出液は、例えば枇杷の葉の熱湯抽出液が、江戸時代以降“枇杷葉湯”として特に夏季に飲用されていたほか、長寿で知られるカシミールのフンザ地方では長年杏の種子仁を常食する習慣があることなどから、人体に無害安全であり、有害・毒性物質は一切含有されていないことが自明である。  Extraction from an amygdalin-containing plant is obtained, for example, by extracting leaves, fruits, seeds, stems, etc. of an amygdalin-containing plant with water or aqueous alcohol, for example, an aqueous solution of 20 to 80% by weight ethanol or isopropanol. Specifically, plants containing amygdalin, such as peach seed, apricot kernel, persimmon leaf or its seed, and plum seed seed, and extracts and extracts thereof with water or aqueous alcohol solutions are exemplified. These extracts are, for example, Kashiwanoha hot water extract, which has been drunk in summer especially as “Kashiwayu” since the Edo period. It is self-evident that it is safe and harmless to the human body because it has customs and does not contain any harmful or toxic substances.

アミグダリン含有植物の抽出溶媒としては、水又は親水性溶媒、たとえばエタノール、イソプロパノールなどの水含有アルコール液などが用いられるが、熱水や20乃至80重量%程度の水性エタノール溶液が好ましい。  As an extraction solvent for the amygdalin-containing plant, water or a hydrophilic solvent, for example, a water-containing alcohol solution such as ethanol or isopropanol is used, but hot water or an aqueous ethanol solution of about 20 to 80% by weight is preferable.

抽出は、市販の杏仁や桃仁、青梅から得られる種子、又は枇杷の種子など及び例えば3年生以上の枇杷の葉に、重量比で2乃至10倍量の水を加えて水が半量と成るまで加熱沸騰させるか、又は同量の25乃至35重量%のアルコール水溶液を加えて室温で又は適宜に間歇的に加温して30日ないし40日間静置することによって、薄茶色の透明溶液が得られ、その後必要に応じてろ過すればよい。  Extraction is done by adding 2 to 10 times the amount of water by weight to seeds obtained from commercially available apricot seeds, peach seeds, ome, or persimmon seeds, etc. A light brown transparent solution can be obtained by heating to boiling or adding the same amount of an aqueous solution of 25 to 35% by weight of alcohol and allowing to stand at room temperature or intermittently as appropriate for 30 to 40 days. And then filtered as necessary.

得られた抽出液は、ろ過した後そのまま又は必要に応じて濃縮若しくは蒸発乾固させて粉末状の抽出物とした後、常法により皮膚及び毛髪に適用される各種香粧料に特定量を配合すればよい。  The obtained extract is filtered or concentrated or evaporated to dryness as it is to obtain a powdery extract, and then a specific amount is added to various cosmetics applied to the skin and hair by a conventional method. What is necessary is just to mix | blend.

かかる抽出液又は抽出物は、最終仕上がり香粧料に対して上記した純粋・単体アミグダリンの配合量となる配合比率範囲で配合すればよい。  Such an extract or extract may be blended in the blending ratio range that is the blending amount of the above pure and simple substance amygdalin with respect to the final finished cosmetic.

アミグダリン又はアミグダリン含有植物の抽出液又は抽出物は、全ての剤型の皮膚及び毛髪に使用する香粧料に配合することによって、前記した好ましい効果・作用を発揮出来る他、パラベン類などの保存剤の使用を省略出来るか又はその射容量を低減することが出来る。なお香粧料の具体的な例としては、例えば石鹸、クレンジングクリーム、洗顔クリーム、ボデーシャンプー、シェービングクリームなどの洗浄料、各種化粧水、乳液、ミルキーローションなど各種スキンローション類、エモリエントクリームなど各種スキンクリーム類、マッサージクリーム、フォームパックなどの賦活料、エッセンス、サンプロテクトミルク、サンスクリーン剤などの美白・日焼け止め、防シワ・防シミ・抗老化化粧品などの基礎化粧品、制汗・デオドラント、オーデコロンなどフレグランス製品、バスオイルなど浴用剤、口紅などの仕上がり化粧品など、またヘアーシャンプー、ヘアーリンス、ヘアートニックなどの毛髪化粧品、更にはマウスウオッシュや歯磨きなどのオーラルケアー製品が挙げられる。  Amygdalin or an amygdalin-containing plant extract or extract can exhibit the above-mentioned preferred effects and actions by being added to cosmetics used for skin and hair of all dosage forms, and also contains preservatives such as parabens. Can be omitted or its firing capacity can be reduced. Specific examples of cosmetics include, for example, soaps, cleansing creams, facial cleansing creams, body shampoos, shaving creams, and other skin lotions, lotions, emulsions, milky lotions and other skin lotions, emollient creams and various skins. Activators such as creams, massage creams, foam packs, essences, sun protection milks, whitening and sunscreens such as sunscreens, basic cosmetics such as anti-wrinkle, anti-stain and anti-aging cosmetics, antiperspirants, deodorants, and colognes Examples include fragrance products, bath oils such as bath oil, finished cosmetics such as lipsticks, hair cosmetics such as hair shampoos, hair rinses, hair arts, and oral care products such as mouthwashes and toothpastes.

なお、アミグダリン又はアミグダリン含有植物の抽出物は、汗臭や皮脂臭などの体臭、頭皮や頭髪の臭気また口臭などの異臭を防止・抑制・除去するためには、香粧料とすることなく、水又はエタノール水溶液を用いた適当な濃度のアミグダリン含有溶液として好ましくはそのまま単独で例えば噴霧などにより外用することも出来る。かかるアミグダリン含有溶液は、人体だけでなくペット類や衣類、カーペットなどの防臭・消臭するためにも、またタバコ臭など室内、車内などの閉鎖空間内の異臭の予防・除去にも同様に噴霧などにより適用できる  In addition, amygdalin or an extract of amygdalin-containing plant is not used as a cosmetic in order to prevent / suppress / remove body odors such as sweat odor and sebum odor, odor of scalp and hair and bad breath, etc. An amygdalin-containing solution having an appropriate concentration using water or an aqueous ethanol solution is preferably used alone as it is, for example, by spraying. Such an amygdalin-containing solution is sprayed not only for the human body, but also for preventing and removing odors from pets, clothes, carpets, etc., as well as to prevent and remove off-flavors such as tobacco odors in closed spaces such as indoors and cars. Applicable by

以下に実施例を記載して本発明をさらに詳細に説明するが、実施例3以降において調製した香粧料は、保存剤を添加しなくても変質・腐敗しなかった。  Hereinafter, the present invention will be described in more detail with reference to Examples. However, the cosmetics prepared in Examples 3 and after were not altered or spoiled without adding a preservative.

抽出実施例1Extraction Example 1

鹿児島産枇杷の種子を乾燥させ、薄皮を剥いだもの30グラムに25%濃度のアルコール水溶液300ccを加えて、室温で3ヶ月間放置した後ろ過して、薄茶色の水性アルコール抽出液を得た。またその一部を減圧下に蒸発乾固させて薄茶色粉末を得た。  After drying seeds from Kagoshima, 30 gram of peeled skin was added with 300 cc of 25% alcohol aqueous solution, allowed to stand at room temperature for 3 months, and then filtered to obtain a light brown aqueous alcoholic extract. . A part thereof was evaporated to dryness under reduced pressure to obtain a light brown powder.

抽出実施例2Extraction Example 2

鹿児島産枇杷の種子を乾燥させ、薄皮を剥いだ後二つ割にしたもの30グラムに35%濃度のアルコール水溶液300ccを加えて、室温で2ヶ月間放置した後ろ過して、薄茶色の水性アルコール抽出液を得た。またその一部を減圧下に蒸発乾固させて薄茶色粉末を得た。  After drying Kagoshima cocoon seeds, peeling off the skin and splitting it in half, adding 300 cc of 35% alcohol aqueous solution to 30 grams, allowing to stand at room temperature for 2 months, filtering, and adding a light brown aqueous solution An alcohol extract was obtained. A part thereof was evaporated to dryness under reduced pressure to obtain a light brown powder.

抽出実施例3Extraction Example 3

市販の中国産杏仁及び30グラムに35%濃度のアルコール水溶液300ccを加えて、室温で2ヶ月間放置した後ろ過して、薄茶色の水性アルコール抽出液を得た。またその一部を減圧下に蒸発乾固させて薄茶色粉末を得た。  300 cc of a 35% aqueous alcohol solution was added to 30 grams of commercially available Chinese apricot kernels and left standing at room temperature for 2 months, followed by filtration to obtain a light brown aqueous alcoholic extract. A part thereof was evaporated to dryness under reduced pressure to obtain a light brown powder.

抽出実施例4Extraction Example 4

三年生以上の枇杷の葉を採取し、水洗した乾燥させ、次いでほぼ1センチメートル四方に鋏で切断した。このように処理した枇杷の葉30グラムに35%濃度のアルコール水溶液200ccを加えて、室温で2ヶ月間放置した後ろ過して薄茶色の水性アルコール抽出液を得た。またその一部を減圧下に蒸発乾固させて薄茶色粉末を得た。  Bamboo leaves over 3rd year were collected, washed with water, dried, and then cut with a cocoon approximately 1 cm square. To 30 grams of bamboo leaves treated in this manner, 200 cc of 35% alcohol aqueous solution was added, left at room temperature for 2 months, and then filtered to obtain a light brown aqueous alcoholic extract. A part thereof was evaporated to dryness under reduced pressure to obtain a light brown powder.

抽出実施例5Extraction Example 5

市販の桃仁30グラムに35%濃度のアルコール水溶液300ccを加えて、室温で2ヶ月間放置した後ろ過して、薄茶色の水性アルコール抽出液を得た(試料5とする)。またその一部を減圧下に蒸発乾固させて薄茶色粉末を得た。  To 30 grams of commercially available peach seed, 300 cc of 35% strength aqueous alcohol solution was added, allowed to stand at room temperature for 2 months, and then filtered to obtain a light brown aqueous alcoholic extract (referred to as sample 5). A part thereof was evaporated to dryness under reduced pressure to obtain a light brown powder.

抽出実施例6Extraction Example 6

市販アミグダリン(東京化成工業((株))製−日本、東京)を25%アルコール水溶液に加温下に溶解し、1.5%アミグダリン溶液を得た。  Commercially available amygdalin (manufactured by Tokyo Chemical Industry Co., Ltd., Tokyo, Japan) was dissolved in a 25% alcohol aqueous solution under heating to obtain a 1.5% amygdalin solution.

固形石鹸の調製Preparation of bar soap

固形石鹸の処方例((全量を100.0とする)
セタノール 10.00
ヂブチルヒドロキシトルエン 0.01
抽出実施例1の抽出物 1.0
着色料・香料 微量
天然油脂石鹸ベース 残量
上記処方に成分を充分混練りした後押出し成形機で押出し、次いで型打ちして固形石鹸を製造した。
この石鹸を1ヶ月間使用したところ、肌あれが改善されまた皮膚のツッパリ感が無く、肌に潤いが出たほか、擦過傷も早期に治癒して創傷治癒促進効果が認められた。なお、抽出実施例2乃至5の抽出物についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Example of soap formula (total amount is 100.0)
Cetanol 10.00
Dibutylhydroxytoluene 0.01
Extract of Extraction Example 1 1.0
Colorant / fragrance Trace amount Natural oil / fat soap base remaining amount The ingredients were sufficiently kneaded into the above formulation, extruded with an extrusion molding machine, and then stamped to produce a solid soap.
When this soap was used for 1 month, it had improved skin roughness, no skin sensation, moisturized the skin, and the wounds were healed early and an effect of promoting wound healing was observed. In addition, the same effect was recognized also about the extract of extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

スキンクリームの調製Preparation of skin cream

クリームの処方例(全量を100.0とする)
モノステアリン酸グリセリン 5.00
ステアリン酸 5.00
モノステアリン酸ポリエチレングリコール 2.00
流動パラフィン 10.00
トリオクタン酸グリセリル 10.00
抽出例1の抽出液 7.00
1,3−ブチレングリコール 5.00
メチルパラベン 0.10
エデト酸二ナトリウム 0.01
精製水 100.00になるまで残量
上記成分を常法でスキンクリームとし、2ヶ月間顔面に使用したところ、肌荒れが無くなり、保湿感のある肌となり、シミの沈着色素が薄れる効果が認められた。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Cream formulation example (total amount is 100.0)
Glycerol monostearate 5.00
Stearic acid 5.00
Polyethylene glycol monostearate 2.00
Liquid paraffin 10.00
Glyceryl trioctanoate 10.00
Extract liquid of Extraction Example 1 7.00
1,3-butylene glycol 5.00
Methylparaben 0.10
Edetate disodium 0.01
Purified water Remaining amount until 100.00 The above ingredients are used as a skin cream in the usual way, and when used on the face for 2 months, skin roughening is eliminated, moisturizing skin is obtained, and the effect of fading stain pigments is observed. It was. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

スキンクリームの調製Preparation of skin cream

上記実施例3の処方に絹セリシン抽出ゲル5.00重量%を加え且つメチルパラベンを除去してクリームを製造し、2ヶ月間使用したところ、肌荒れが無くなり、保湿感の高い肌となり、シミが薄れ又美白効果が認められた。  A cream was prepared by adding 5.00% by weight of silk sericin extraction gel to the formulation of Example 3 above and removing methylparaben, and when used for 2 months, there was no rough skin, the skin became highly moisturized, and the spots faded. A whitening effect was also observed.

スキンローションの調製Skin lotion preparation

ローションの処方例(全量を100.0とする)
エタノール 15.00
ポリオキシエチレン硬化ひまし油 8.00
1,3−ブチレングリコール 4.00
ヤシ油 1.00
クエン酸ナトリウム 0.30
抽出実施例1の抽出液 5.0
エデト酸ナトリウム 0.01
精製水 残量
上記成分を常法に従って混合してローションを作製し、2ヶ月間顔面に塗布したところ肌荒れが収まりまたシミや老人斑が殆ど消失した。また日焼けが消失し、皮膚の潤いや美白が認められた。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Lotion formulation example (total amount is 100.0)
Ethanol 15.00
Polyoxyethylene hydrogenated castor oil 8.00
1,3-butylene glycol 4.00
Coconut oil 1.00
Sodium citrate 0.30
Extraction liquid of extraction example 1 5.0
Sodium edetate 0.01
Purified water remaining amount The above ingredients were mixed according to a conventional method to prepare a lotion, and when applied to the face for 2 months, rough skin subsided and spots and senile plaques almost disappeared. Sunburn disappeared and skin moisture and whitening were observed. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

スキンローションの調製Skin lotion preparation

上記実施例4の処方において、さらに絹セリシンゲル5.0重量%又はウコンのジュースをそれぞれ5.0重量%ずつ追加配合して混合して日焼け止めローション及び薬用ローションを作製した。
日焼けとめローションを連用したところ日焼けが効果的に防止され、またウコン配合薬用ローションは、中程度の火傷を数日間で治癒させた。なおこれらのローションは、パラベンなどの防腐剤の配合を必要としなかった。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
In the formulation of Example 4 above, 5.0% by weight of silk sericin gel or 5.0% by weight of turmeric juice was added and mixed to prepare sunscreen lotions and medicated lotions.
When suntan and lotion were used continuously, sunburn was effectively prevented, and the turmeric combination lotion healed moderate burns in a few days. These lotions did not require preservatives such as parabens. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

乳液の調製Preparation of emulsion

乳液の処方例(全量を100.0とする)
モノステアリン酸ポリオキシエチレンソルビタン 3.00
ステアリン酸 1.00
モノステアリルグリセリン 1.00
トリオクタン酸グリセリン 4.00
アボガド油 4.00
抽出実施例1の抽出液 7.0
1,3−ブチレングリコール 5.00
キサンタンガム 0.50
香料 適量
グリセリン 0.5
精製水 残量
上記成分を加温して、撹拌乳化させて乳液を作製した。2ヶ月間顔面に使用したところ、肌荒れが無くなり、保湿感のある肌となり、シミの沈着色素が薄れる効果が認められた。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Example of emulsion formulation (total amount is 100.0)
Polyoxyethylene sorbitan monostearate3.00
Stearic acid 1.00
Monostearyl glycerol 1.00
Glycerin trioctanoate 4.00
Avocado oil 4.00
Extraction liquid of extraction example 1 7.0
1,3-butylene glycol 5.00
Xanthan gum 0.50
Perfume appropriate amount Glycerin 0.5
Purified water remaining amount The above ingredients were heated and emulsified with stirring to prepare an emulsion. When used on the face for 2 months, rough skin was eliminated, moisturizing skin was obtained, and the effect of fading the stain pigment was observed. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

軟膏の調製Ointment preparation

軟膏の処方例(全量を100.0とする)
モノステアリン酸ポリエチレングリコール 3.00
ステアリン酸 5.00
モノステアリルグリセリン 5.00
トリオクタン酸グリセリン 10.00
流動パラフィン 10.00
抽出実施例1の抽出物 2.0
秋ウコン破砕物 2.0
1,3−ブチレングリコール 5.00
プロピレングリコール 1.00
香料 適量
精製水 残量
上記成分を加温して、撹拌乳化させて、創傷及び火傷の治癒促進作用を有する皮膚保護軟膏を作製した。なお、抽出実施例2乃至5の抽出物についても同一の効果の軟膏が得られ、また試薬アミグダリンを1重量%配合した場合にも類似した効果の軟膏が得られた。
Example of ointment formulation (total amount is 100.0)
Polyethylene glycol monostearate 3.00
Stearic acid 5.00
Monostearyl glycerin 5.00
Glycerin trioctanoate 10.00
Liquid paraffin 10.00
Extract of Extraction Example 1 2.0
Fall Turmeric Crushed 2.0
1,3-butylene glycol 5.00
Propylene glycol 1.00
Fragrance Appropriate amount Purified water remaining amount The above ingredients were heated and emulsified with stirring to prepare a skin protective ointment having a healing promotion effect on wounds and burns. In addition, the ointment having the same effect was obtained for the extracts of Extraction Examples 2 to 5, and an ointment having a similar effect was obtained when 1% by weight of the reagent amygdalin was blended.

アフタシェーブローションの調製Aftershave lotion preparation

アフターシェーブローションの処方例(全量を100.0とする)
グリセリン 2.00
1%セリシンゲル 5.00
クエン酸ナトリウム 0.30
抽出実施例1の抽出液 15.0
精製水 残量
上記成分を室温で混合してアフターシェーブローションとして、髭剃り後に使用したところ、3日後には肌荒れが無くなり、保湿感のある肌となった。なお、抽出実施例2乃至5の抽出液ついても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Example of aftershave lotion (the total amount is 100.0)
Glycerin 2.00
1% sericin gel 5.00
Sodium citrate 0.30
Extraction liquid of extraction example 1 15.0
Purified water remaining amount The above ingredients were mixed at room temperature and used as an after shave lotion after shaving. After 3 days, the skin became rough and moisturized. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

デオドラントローションの調製Deodorant lotion preparation

デオドラントローションの処方例(全量を100.0とする)
グリセリン 2.00
クエン酸ナトリウム 0.30
抽出例1の抽出液 25.0
香料 適量
精製水 残量
上記成分を常温度で混合して均一溶液とし、入浴後に適量を使用したところ、盛夏時でも汗臭や腋臭など悪臭をほぼ20時間防止でき、その後追加使用して引き続き効果的に防臭することが出来た。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを水性アルコール液として1重量%配合した場合にも類似の効果が認められた。
Example of deodorant lotion (total amount is 100.0)
Glycerin 2.00
Sodium citrate 0.30
Extract liquid of Extraction Example 1 25.0
Perfume Appropriate amount Purified water remaining The above ingredients are mixed at normal temperature to make a uniform solution, and after using the appropriate amount after bathing, it can prevent bad odors such as sweat odor and foul odor for almost 20 hours even in midsummer, and it will continue to be effective after additional use. I was able to deodorize. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended as an aqueous alcohol liquid.

ヘアートニックの調製Preparation of hair art

ヘアートニックの処方例(全量を100.0とする)
エタノール 30.0
1%セリシンゲル 5.0
抽出実施例1の抽出液 15.0
精製水 残量
上記成分を室温で混合してヘアートニックとして、一日当り入浴後及び翌朝の二回2ヶ月間使用したところ、毛根がしっかりとし、髪の艶が改善され、頭髪臭が消えた。また白髪が減少した。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを水性アルコール液として1重量%配合した場合にも類似の効果が認められた。
Hairtonic prescription example (total amount is 100.0)
Ethanol 30.0
1% sericin gel 5.0
Extraction liquid of extraction example 1 15.0
Purified water remaining amount When the above ingredients were mixed at room temperature and used as a hair artic after taking a bath every day and twice in the next morning for 2 months, the hair root was firm, the gloss of the hair was improved, and the hair odor disappeared. In addition, gray hair decreased. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended as an aqueous alcohol liquid.

マウスウォッシュの調製Preparation of mouthwash

マウスウオッシュの処方例(全量を100.0とする)
アズレン 1.0
抽出実施例2の抽出液 4.0
エタノール 10.0
香料 適量
精製水 残量
上記成分を室温で混合してマウスウオッシュシとなし、食間のうがいに使用したところ、口臭が消え、清涼感が得られた。なお、抽出実施例2乃至5の抽出液についても同一の効果が認められ、また試薬アミグダリンを水性アルコール液として1重量%配合した場合にも類似の効果が認められた。
Example of mouse wash formulation (total amount is 100.0)
Azulene 1.0
Extraction liquid of extraction example 2 4.0
Ethanol 10.0
Fragrance Appropriate amount Purified water Remaining The above ingredients were mixed at room temperature to make a mouthwash, and when used for gargle between meals, bad breath disappeared and a refreshing feeling was obtained. In addition, the same effect was recognized also about the extraction liquid of Extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended as an aqueous alcohol liquid.

練り歯磨の調製Preparation of toothpaste

練り歯磨きの処方例(全量を100.0とする)
第二リン酸カルシウム 30.0
炭酸カルシウム 25.0
ラウリン酸ナトリウム 1.0
CMCナトリウム 2.0
ソルビット 15.0
グリセリン 15.0
サッカリン 0.5
香味料 1.0
抽出実施例2の抽出物 1.5
精製水 残量
上記成分を室温で混練りして湿潤歯磨きとなし、朝食前の歯磨きに使用したところ、口臭が消え、口内清涼感が持続して得られた。また口内炎の治癒が促進された。なお、抽出実施例2乃至5の抽出物についても同一の効果が認められ、また試薬アミグダリンを1重量%配合した場合にも類似の効果が認められた。
Toothpaste prescription example (total amount is 100.0)
Dicalcium phosphate 30.0
Calcium carbonate 25.0
Sodium laurate 1.0
CMC sodium 2.0
Sorbit 15.0
Glycerin 15.0
Saccharin 0.5
Flavoring 1.0
Extract of Extraction Example 2 1.5
Purified water remaining amount When the above ingredients were kneaded at room temperature to make a wet toothpaste and used for toothpaste before breakfast, bad breath disappeared and a refreshing feeling in the mouth was obtained. In addition, healing of stomatitis was promoted. In addition, the same effect was recognized also about the extract of extraction Example 2 thru | or 5, and the similar effect was recognized when 1 weight% of reagent amygdalin was mix | blended.

ボディシャンプーBody shampoo

下記配合処方により、ボディーシャンプーを作製し、比較基準とした。
ボディーシャンプーの配合処方例
混合脂肪酸 20.0
ジプロピレングリコール 3.0
塩化ナトリウム 0.5
キレート化剤 0.5
安息香酸ナトリウム 0.5
水酸化カリウム/水 5.8/18.0
ラウリン酸 0.5
ベタイン系洗浄剤 8.0
ジエタノールアマイド系洗浄剤 8.0
グリシン 0.2
抽出実施例1の抽出物 1.0
グリチルリチン酸ジカリウム 適量
水 全量を100とする残量
上記成分を常法に従い混合・混練りしてボディーシャンプーとなし、食間入浴時に使用したところ、消臭性能及び洗浄性能が改善され、泡性能、すすぎ・肌感触も優れていた。
また抽出実施例1の抽出物を用いてシェービングフォームやシェービングクリームに加工したところ、深剃りが可能で、しかもアフターシェービングローションの塗布を必要とせず、髭剃り部の過剰の角質化促進を防止できた。なお、抽出実施例2乃至5の抽出物についても同一の効果の洗浄剤が得られ、また試薬アミグダリンを1重量%配合した場合にも類似の効果の洗浄剤が得られた。
A body shampoo was prepared according to the following formulation and used as a reference for comparison.
Body shampoo formulation example Mixed fatty acids 20.0
Dipropylene glycol 3.0
Sodium chloride 0.5
Chelating agent 0.5
Sodium benzoate 0.5
Potassium hydroxide / water 5.8 / 18.0
Lauric acid 0.5
Betaine detergent 8.0
Diethanolamide detergent 8.0
Glycine 0.2
Extract of Extraction Example 1 1.0
Dipotassium glycyrrhizinate Appropriate amount Water Remaining amount of 100% The above ingredients are mixed and kneaded according to conventional methods to form a body shampoo. When used during bathing between meals, the deodorizing performance and cleaning performance are improved, foam performance, rinsing・ Excellent skin feel.
Moreover, when the shaving foam or shaving cream was processed using the extract of Extraction Example 1, deep shaving is possible, and it is not necessary to apply after shaving lotion, and excessive keratinization of the shaved portion can be prevented. It was. In addition, the detergent of the same effect was obtained also about the extract of extraction Example 2 thru | or 5, and when the reagent amygdalin was mix | blended 1 weight%, the detergent of the similar effect was obtained.

アミグダリン又は例えば杏仁、桃仁、枇杷種子、梅種子仁、枇杷葉などのアミグダリンを含有する植物の抽出液若しくは抽出物を配合してなる、機能性香粧料は、皮膚及び毛髪に適用した場合、抗酸化作用、整肌作用、創傷治癒促進作用、抗菌・抗黴作用、清浄化作用、防臭・消臭作用などを発揮して、皮膚及び毛髪の生理機能の維持・改善ももたらし、その結果特に皮膚及び毛髪の老化、退化や変異を防止すると共に外傷、しみ、しわ、肌荒れや老人斑及び白髪、脱毛など皮膚及び毛髪の種々の障害・病変を修復・治癒して健常に維持するのに有効である。  When applied to the skin and hair, a functional cosmetic comprising an amygdalin or an extract or extract of a plant containing amygdalin such as apricot kernel, peach seed, persimmon seed, plum seed seed, persimmon leaves, etc. Antioxidant effect, skin conditioning effect, wound healing promotion effect, antibacterial / anti-wrinkle effect, cleansing effect, deodorant / deodorant effect, etc., leading to maintenance and improvement of skin and hair physiology, especially as a result Prevents skin and hair from aging, degeneration and mutation, and is effective in repairing and healing various disorders and lesions of skin and hair such as trauma, spots, wrinkles, rough skin, senile plaques, gray hair, and hair loss. It is.

Claims (3)

アミグダリン又はアミグダリン含有植物の抽出物を配合されてなる香粧料。  A cosmetic comprising amygdalin or an amygdalin-containing plant extract. アミグダリン含有植物の抽出物が、杏仁、桃仁、枇杷種子、梅種子仁又は枇杷葉の水又は水性アルコール溶液による抽出物である、請求項1において記載された香粧料。The cosmetic according to claim 1, wherein the extract of the amygdalin-containing plant is an extract of apricot kernel, peach seed, persimmon seed, plum seed kernel or persimmon leaf water or aqueous alcohol solution. アミグダリン又はアミグダリン含有植物の抽出物が、アミグダリン単体として0.1乃至20.0重量%配合される、請求項1又は2において記載された香粧料。The cosmetic according to claim 1 or 2, wherein amygdalin or an extract of an amygdalin-containing plant is blended in an amount of 0.1 to 20.0% by weight as a single substance of amygdalin.
JP2004382301A 2003-12-06 2004-12-04 Improved scented cosmetic Pending JP2005187474A (en)

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WO2006008917A1 (en) * 2004-07-15 2006-01-26 Lion Corporation Deodorant agent, deodorant preparation and method of deodorant treatment for fiber
JP2007084511A (en) * 2005-09-26 2007-04-05 Meiko Shoji Kk Plant essence-impregnated material for cough suppression
JP2007290983A (en) * 2006-04-21 2007-11-08 Lion Corp Deodorizing composition and deodorant preparation
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CN109260282A (en) * 2018-03-19 2019-01-25 株式会社世普劳统 Cosmeceutical, plant extracts and its preparation method and application
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JP2006052198A (en) * 2004-07-15 2006-02-23 Lion Corp Deodorant, deodorant preparation and method of deodorizing treatment of fiber
JP2007084511A (en) * 2005-09-26 2007-04-05 Meiko Shoji Kk Plant essence-impregnated material for cough suppression
JP2007290983A (en) * 2006-04-21 2007-11-08 Lion Corp Deodorizing composition and deodorant preparation
JP2007308433A (en) * 2006-05-19 2007-11-29 S F C:Kk Antimicrobial agent
JP2008063255A (en) * 2006-09-05 2008-03-21 Kochi Univ Inhibitor of allergic disease
JP2008189609A (en) * 2007-02-06 2008-08-21 Shiseido Co Ltd Vegfc production enhancer
JP2011105693A (en) * 2009-11-20 2011-06-02 Kyoei Kagaku Kogyo Kk Cosmetic
JP2013143938A (en) * 2011-12-16 2013-07-25 Suntory Holdings Ltd Beverage containing peach nuclear extract
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CN105343729A (en) * 2015-11-30 2016-02-24 王浩 Health-care skin-beautifying bath decoction
KR20190133176A (en) 2017-03-07 2019-12-02 릴리스 카가쿠고교 가부시키가이샤 Deodorant, Antibacterial Agent
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KR102015176B1 (en) 2017-09-27 2019-08-27 대구한의대학교산학협력단 Japanese apricot essential oil and cosmetic composition for skin whitening containing the same
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JP2020132548A (en) * 2019-02-15 2020-08-31 株式会社バスクリン Method for producing amygdalin-containing plant extract
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