JP4179971B2 - Moisturizing plant extract and external preparation, cosmetic, bath preparation and detergent containing the extract - Google Patents

Description

  The present invention relates to a moisturizing plant extract and a cosmetic, a bath preparation and a detergent composition containing the extract, which moisturizes the skin and hair and provides a healthy and healthy skin or hair. The present invention provides a composition useful for maintenance and regeneration. That is, dryness, rough skin, cracks, redheads, dandruff, kayumi, inflammatory diseases, prevention, reduction or improvement of skin, and dryness, dryness, split ends, cut hair, gloss, etc. The present invention relates to an effective moisturizing plant extract and a cosmetic, a bath preparation and a detergent composition containing the extract.

  Human skin and hair are moderately moisturized when healthy and usually do not require special care, but various environmental factors (e.g. temperature change, humidity change, light, water and water) Etc.), contact with detergents, etc., or aging often causes changes and troubles. That is, the skin and hair with a reduced moisturizing function are dried and hard, and the gloss and elasticity are lost, resulting in a crisp state. In recent years, such dry skin has been pointed out to be associated with atopic dermatitis, which is rapidly increasing, and may cause various skin troubles. In addition, troubles such as loss of luster, split ends and cut hairs occur even in the hair. Further progress is considered to cause serious conditions such as spots, wrinkles and hair loss.

  Conventionally, in order to prevent the skin and hair from drying, external extracts such as cosmetics can be used alone or each extract of the constituent herbal extracts of citrus, peony, peonies, tonin, bukkyou, buttonpi, licorice and ginger. It has been used as a mixed blend of products. For example, cosmetics containing a hydroquinone glycoside and a herbal extract having a whitening effect are known. Examples of the herbal extract include mulberry (sohakuhakuhi), aloe, peonies, oxon, hamamelis, salamander, honeysuckle, bituminous, Keihi, Saishin, Nepenthes, Hamago, Sanshuyu, Auren, Morning Glory, Clara, Hosobaokera, Yomobi, Perilla, Shikon, Bodaiju, Chamomile, Toki, Maronier, Senkyu, Tonin, Sage, Salvia, Ages, Shoshoku, Yakushuku , Kokuboku, Rosemary, Genokosho, Kina, Birch, Clove, Enmeiso, Melissa, Nantenjitsu, Basil, Ginkgo, Eletrocock, etc. have been proposed (Patent Document 1). In addition, an external preparation for skin containing an orange extract and / or licorice extract and a lactic acid bacteria fermentation solution has also been proposed (Patent Document 2). And four kinds of single extracts of Auren, Abou, Ogon and Sanshishi are used in combination, and one or more herbal extracts of Toki, Senkyu, Peonies, Giant, Forsythia, Keigai, Yakuinin, Psycho, and Licorice are combined. A cosmetic is also proposed (Patent Document 3).

  Similarly, glycerin, propylene glycol, 1,3-butylene glycol, other polyhydric alcohols, fats and oils components, amino acids, proteins, polysaccharides, mucopolysaccharides, and the like can also be used to prevent skin and hair from drying. It has been used as an external preparation.

  The purpose seen in these is to create a film by applying to the skin and hair, to prevent the transpiration of moisture, and to devise to make it closer to the stratum corneum component called NMF (Natural Moisturizing Factor) Met.

JP-A-5-139950 JP-A-5-238925 Japanese Patent Laid-Open No. 9-30931

  However, conventional moisturizing components have not yet been satisfied in terms of touch, durability of moisturizing effect, safety, and physicochemical stability. In particular, the moisturizing effect of the conventional components is temporary, and it is difficult to say that the composition is externally sufficient in terms of maintaining and regenerating healthy skin or hair, such as prevention or improvement of rough skin and split ends.

  The present invention solves such a problem and contains a moisturizing plant extract that continues to have a moisturizing effect for a long time and the extract, and for skin, dryness, rough skin, cracks, red snapper, dandruff, Kayumi, for preventing, reducing or ameliorating inflammatory diseases, and for hair, cosmetics or bath preparations effective for drying, dryness, split ends, cut hair, gloss, etc., or rough skin, cracks, redheads, etc. The present invention provides an improved detergent composition that is less likely to cause skin troubles.

  In order to solve the above-mentioned problems, the present inventors searched various plant extracts and mixtures thereof, and as a result, the extract having the same composition as the Kampo formula called Kojito has a synergistically excellent moisturizing effect. And the present invention was completed. That is, the present invention is a moisturizing plant extract comprising an extract of a mixture of Keishi, Peonies, Tonin, Bukkyou, Boppi, Licorice and Pepper, and more specifically, 0.3 to 8 parts by weight (hereinafter the same) ), 0.3-8 parts of peonies, 0.3-8 parts of peony, 0.3-8 parts of boucheon, 0.3-8 parts of button pie, 0.1-6 parts of licorice and 0.1-6 parts of pepper A moisturizing plant extract comprising an extract of a mixture of the following: more specifically, 2-5 parts (parts by weight) of citrus, 2-5 parts of peony, 2-5 parts of tonin, 2-5 parts of peony, A moisturizing plant extract comprising an extract of a mixture of 2 to 5 parts of button pi, 0.3 to 4 parts of licorice and 0.3 to 4 parts of pepper, more specifically extraction with water or alcohols or mixtures thereof Thing The cosmetic composition, bath agent composition or detergent composition characterized by containing the moisturizing plant extract.

  The moisturizing plant extract of the present invention continues to have a moisturizing effect for a long time, and the cosmetic and bath preparation containing the extract prevent dryness, rough skin, cracks, red snapper, dandruff, kayumi and the like on the skin. It is effective for reduction or improvement, and for hair, such as dryness, dryness, split ends, cut hair, and gloss. In addition, even in household detergents that have been concerned about skin troubles such as rough skin, cracks, and redheads, the moisturizing plant extract of the present invention eases such troubles so that it does not easily occur, and is a detergent that touches the skin. A composition can be provided.

The plants used in the present invention are shown below, and any of them can use leaves, stems, roots, flowers, seeds or whole plants. In addition, herbal medicines originating from the following plants may be used.
(1) Keishin Cinnamomum cassia Blume
(2) Peony Paeonia lactiflora Pallas (button family)
(3) Prunus persica Batsch var. Davidiana Maximowicz (Rosaceae)
(4) Poria cocos Wolf
(5) Buttonpi Paeonia suffruticosa Andrews (Paeonia moutan Sims)
(6) Daylily Grycyrrhiza glabra Linne (Fabaceae)
(7) Zingiber officinale Rosco (Ginger family)
However, the type of each herbal medicine is not limited to this, and variants, congeners, and other related species can also be used.

  Kojito is a combination of seven species: Keishi, Peonies, Tonin, Bukuryo, Buttonpi, Kanzo, and Pepper. They are relatively healthy and sometimes complain of lower abdominal pain, stiff shoulders, head weight, dizziness, and cold feet. For example, it is said that taking decoction is effective for people with irregular menstruation, menstrual abnormalities, menstrual pain, climacteric disorder, bloody thrombosis, stiff shoulders, dizziness, head weight, bruise (bruise), moistness, and spots. [Natural product pharmacology (Shuji Itokawa, Taichi Omoto, Masahiro Nagai, Riki Furuya, published by Asakura Shoten, April 10, 1987)].

  Kojito is relatively strong and is used for those with lower abdominal pain, stiff shoulders, headache, dizziness, hot flashes, etc. In addition to irregular menstruation, menstrual pain, menopause, etc., it is said that it is effective to take the decoction for people with motility, rheumatism, and neuralgia [Natural Drug Encyclopedia (published by Takuo Okuda, Yodogawa Shoten, Showa March 3, 1981)].

  The active ingredient is extracted from these plants using a suitable solvent. Examples of the solvent include water, alcohols (for example, lower alcohols such as methanol, absolute ethanol, and ethanol, or polyhydric alcohols such as 1,3-butylene glycol, propylene glycol, and dipropylene glycol). Any mixture can be used. Moreover, after extraction, the extract can be diluted or concentrated and dried as necessary.

  The production method is not particularly limited, and may be in the range of the boiling point of the solvent at normal temperature or normal pressure, and a microwave extraction method or a supercritical extraction method may be used. After extraction, filtration or ion exchange resin may be used for adsorption, decolorization, and purification to form a solution, paste, gel, or powder. In many cases, it can be used as it is, but if necessary, further purification treatment such as deodorization and decolorization may be added as long as the effect is not affected. An activated carbon column or the like may be used, and usual means generally applied depending on the extracted substance may be arbitrarily selected.

  The herbal medicine used in the present invention provides an effective extract from a combination of seven kinds extracted. Therefore, it is more effective than those extracted individually from each other, arbitrarily extracted by combining up to 6 kinds of plants, and mixed with each extract or extract. It should be noted that by extracting and combining seven kinds of plants, the result is that the persistence of the moisturizing effect is further improved, and the improvement effect on rough skin, dandruff, kayumi and inflammatory diseases is further improved. It seems to be sufficiently meaningful to use a product extracted by combining seed plants.

  The compounding amount of each herbal medicine used in the present invention is as follows. The amount described in the Supervision of the Bureau of Affairs, published by Yakuho Jihosha, April 30, 1992, 4th edition, 12 printing) is preferable, and generally 0.3 to 8 parts (parts by weight) (hereinafter the same), Peonies 0.3-8 parts, Tonin 0.3-8 parts, Bukuryu 0.3-8 parts, Buttonpi 0.3-8 parts, Licorice 0.1-6 parts and Pepper 0.1-6 parts. However, particularly preferred amounts are 2 to 5 parts of citrus, 2 to 5 parts of peony, 2 to 5 parts of peony, 2 to 5 parts of broomfish, 2 to 5 parts of button pi, 0.3 parts of licorice ~ 4 parts and 0.5-3 parts of Tokyo.

  In addition to the essential moisturizing plant extract of the present invention, the cosmetic composition, bath preparation composition and detergent composition according to the present invention are, for example, bases usually used in cosmetics as described below, It can be produced by using additives and the like together.

  (1) Various fats and oils: avocado oil, almond oil, fennel oil, sesame oil, olive oil, orange oil, orange rafa oil, sesame oil, cocoa butter, chamomile oil, carrot oil, cucumber oil, beef tallow fatty acid, cucumber oil, safflower Oil, shea fat, liquid shea fat, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil, palm oil, palm kernel oil, owl, Coconut oil, beef tallow, lard, or hydrogenated products of these oils (hardened oil, etc.).

  (2) Waxes: beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax, squalene, squalane, pristane and the like.

  (3) Mineral oil: liquid paraffin, petrolatum, paraffin, ozokelide, ceresin, microcrystalline wax and the like.

  (4) Fatty acids: natural fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tall oil, lanolin fatty acid, isononanoic acid, caproic acid, 2 -Synthetic fatty acids such as ethylbutanoic acid, isopentanoic acid, 2-methylpentanoic acid, 2-ethylhexanoic acid and isopentanoic acid.

  (5) Alcohols: natural alcohols such as ethanol, isopyropanol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, phytosterol, and synthetic alcohols such as 2-hexyldecanol, isostearyl alcohol, 2-octyldodecanol.

  (6) Polyhydric alcohols: ethylene oxide, ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene oxide, propylene glycol, di Propylene glycol, polypropylene glycol, 1,3-butylene glycol, 1,2-pentanediol, glycerin, diglycerin, pentaerythritol, sorbitol, mannitol and the like.

  (7) Esters: isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate , Diethyl phthalate, dibutyl phthalate, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate, and the like.

  (8) Metal soaps: aluminum stearate, magnesium stearate, zinc stearate, calcium stearate, zinc palmitate, magnesium myristate, zinc laurate, zinc undecylenate and the like.

  (9) Gum, sugars or water-soluble polymer compounds: gum arabic, benzoin rubber, dammar gum, guaiac oil, Irish moss, karaya gum, tragacanth gum, carob gum, quinseed, agar, casein, lactose, fructose, sucrose or esters thereof , Trehalose or derivatives thereof, dextrin, gelatin, pectin, starch, carrageenan, carboxymethyl chitin or chitosan, hydroxyalkyl (C2-C4) chitin or chitosan to which alkylene (C2-C4) oxide such as ethylene oxide is added, low molecule Chitin or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid or salt thereof, hyaluronic acid or salt thereof, chondroitin sulfate or salt thereof, heparin, ethylcellulose, methylcellulose , Carboxymethyl cellulose, carboxyethyl cellulose, sodium carboxyethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, nitrocellulose, crystalline cellulose, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylate, polyethylene oxide, polypropylene oxide, etc. Polyalkylene oxide or a crosslinked polymer thereof, carboxyvinyl polymer, polyethyleneimine and the like.

  (10) Surfactant: Anionic surfactant (alkyl carboxylate, alkyl sulfonate, alkyl sulfate ester salt, alkyl phosphate ester salt), cationic surfactant (alkyl amine salt, alkyl quaternary ammonium salt), Amphoteric surfactant [carboxylic acid type amphoteric surfactant (amino type, betaine type), sulfate ester type amphoteric surfactant, sulfonic acid type amphoteric surfactant, phosphate ester type amphoteric surfactant], nonionic surfactant Agents (ether type nonionic surfactants, ether ester type nonionic surfactants, ester type nonionic surfactants, block polymer type nonionic surfactants, nitrogen-containing type nonionic surfactants), other surfactants Agents (natural surfactants, derivatives of protein hydrolysates, polymer surfactants, surfactants containing titanium and silicon, Carbon-based surface active agent), such as.

  (11) Various vitamins Vitamin A group: retinol, retinal (vitamin A1), dehydroretinal (vitamin A2), carotene, lycopene (provitamin A), vitamin B group: thiamine hydrochloride, thiamine sulfate (vitamin B1), Riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), folic acid, nicotinic acids, pantothenic acids, biotins, choline, inositols, vitamin C group: vitamin C acid or derivatives thereof, vitamin D group: Ergocalciferol (vitamin D2), cholecalciferol (vitamin D3), dihydrotaxosterol, vitamin E group: vitamin E or derivatives thereof, ubiquinones, vitamin K group: phytonadione (vitamin K1), menaquinone (vitamin K2), Menadione (vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, γ-oryzanol, orotic acid, vitamin Ps (rutin, eliocitrin, hesperidin), vitamin U and the like.

  (12) Various amino acids: valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxy Amino acid derivatives such as lysine, arginine, ornithine, histidine, and their sulfates, phosphates, nitrates, citrates, or pyrrolidone carboxylic acids.

  (13) Various additives derived from plant or animal materials: These are processed in a conventional manner according to the type and form of the product to be added (for example, pulverization, milling, washing, hydrolysis, fermentation, Purify, squeeze, extract, fractionate, filter, dry, pulverize, granulate, dissolve, sterilize, adjust pH, deodorize, decolorize, etc.) And serve.

  The solvent used for extraction may be selected in consideration of the intended purpose and type of the product to be provided, or the processing performed later. Usually, water, a water-soluble organic solvent (for example, ethanol, propylene glycol) It is desirable to use one or a mixture of two or more selected from 1,3-butylene glycol and the like. However, when it is not preferable to contain an organic solvent depending on the application, it is sufficient to use only water or ethanol that can be easily removed after extraction, and it may be used alone or in any mixture with water. The thing extracted and extracted may be sufficient.

  In addition, when using additives derived from plant or animal-based ingredients for systemic or topical external preparations and cosmetics, not only the protection of skin and hair, but also moisturizing, improvement of touch / feel, imparting flexibility, stimulation Relaxation, stress relief by fragrance, cell activation (cell aging prevention), suppression of inflammation, improvement of skin and hair quality, prevention of rough skin and its improvement, hair growth, hair growth, hair loss prevention, imparting gloss, cleansing effect, In addition to cosmetic effects such as fatigue relief, blood flow promotion, and bathing effects, effects such as flavoring, deodorizing, thickening, preserving, and buffering can also be expected.

  In addition to this, expect various cosmetic and medicinal effects of each of the raw materials known so far, and combine them to enhance the target effect or to be multifunctional. It is also possible to make the product expected to be effective.

Specific plants (herbal medicines) used as raw materials include, for example, almond, eye, blue quail, aoki, aokiri or kenashiaokiri, aotsuki rafuji, acacia, red pepper, red currant, red grapes, redwood (logwood), red mulberry, red pine, red sage , Agi, Akikaramatsu, Akinire, Aguahe (Amanite palm), Akebei, Asa, Maruba Asagao or Asagao, Hydrangea, Ashitaba, Azuki, Acerola, Asenyaku, Achira (Shokuyo Kanna), Anise, Abemakaki, Ama, Achacha, Ama Amana, Amaranthus (Amaranthus, Hagatetou, Himagatetou, Senninkoku, Sugimorigateto, Hosoaogeito, Aogateto, Haribiyu, Amaranthus Hippochondriax), Amigasayuri or Baimo, Arcana (Arkanna), Argarovo (Cabbage), Altea, Arnica, Alpinia or Katsudai (Suzukuku), Aloe, Aloe Vera, Angelica, Apricot or Honzu, Ansokkou, Igakouzorina, Ikarisou or Yachima Taikarisou (Inyoukaku), Igusa , Strawberry, Fig, Ichihatsu, Ichibi, Ichiyakusou, Ginkgo, Itohimegi, Locust Bean, Inazuna (Talexiki), Inubiyu (Honagainubiyu), Rice, Inondo, Ibukikakuso, Nettle, Iran Iran, Iwa Cigarette, Iwahiba Iowa, Iwahiba Iowa (Chibosaki), Spiraea, Prunus squirrel, Japanese fennel, Duckweed, Usubasaicin or Keirinsaishin or Oshusaishin, Usbeneia oyster, Usbei Hollyhock, mottled prickly grass, udo or shishiudo, unyadegato (unkalia, cat's claw), ura tea, plum, urajirogashi, waurusushi (kusokokemo), shrimp mandarin, estragon, sorghum, echinashi (squirrel bark, squirrel, squirr , Elcampre, elderberry, elemi, eringi or prerotus erinji, enju, ogi or kibanaogi, auren, giant crow (caloron), oguruma, otsu ryafuji, psyllium, tossed whale, lobster, okera, lobster Yashabushi, bark hawthorn or hawthorn, horsetail (narco lily, scallops), snowy snow or snowy snow, barley, bark , Oka, Okazeri, Oguruma, Okra, Panax Ginseng or Tochibaninjin, Hypericum perforatum or Prunus pertussis or Hypericum perforatum, Odrianthus, Onamomi, Onigumi, Onidoro or Tokoro or Nagadokoro Oyuko, Dutch mustard (watercress), Dutch jellies, Dutch honey bees, olives, oregano, oranges, silkworms, cacao, oysters, oysters, oysters or cantorians, cassias, casinos, gadgets, oaks, cascarillas, casserole, gypsophila, crabs , Caniwa, valerian, birch or fern birch, pumpkin, kapok, kahoku salamander, cattail, chamomile or roman cami Les, camillade, cam cam (camo duck), carax salmon man, crow cucumber or cinna calla cucumber, crow biscak, oats, guarana, carahoo, karaya, karin, garcinia, kawamidori, kawara psycho, kawajisha, kawaratake, kawarana deshi quasi Daylily, Kantarasa, Kandelilla, Kanto, Kanna, Raspberry (Ezo Strawberry, Dutch Strawberry, Shrimp Strawberry, Nawashiro Strawberry, Momiji Strawberry, European Strawberry), Kiwi, Kikarasuuri, Kyoji, Chrysanthemum (Chrysanthemum, Datura, Swordfish, Swords Kidachi Aloe, Kidachi Hakka, Kina, Kinanoki (Shinkona, Akinaki), Kinua (Kinoa), Yellowfin, Gymnema Silvesta, Cat Tub, cabbage, cucumber, gyory, Kiraja saponaria, Kiraya, Kiran Sou, kumquat, betel, goldfish, guava, guayule, quercus infectria, kukui nut, wolfberry, peony, cinnamon, gooseberry, cinnamon , Kupuas, Kumazasa, Kumanzura, Clara, Cranberry, Chestnut, Curkrigo Lachifolia, Grapefruit, Black-bellied Red, Black-bellied, Black-faced Tobacco or Tobacco, Gunby Tuna (Sekimei, Sekimeishi), Kei-gai, Kate-genu, Bara-ken, Pepper Kigushi), Koki-Sekoku, Kishimizukan (Koji, Tachibana, Obi-nimikan, Fuklemikan, Sagamikoji, Ponka , Santara, Koshinbara, Kouseihakka, Kozo, Kocha, Kohone, Kohon, Kouriyan, Koryokukyo, Cilantro, Kourien, Koganebana, Cowberry, Coconut, Goshuyu, Goshostrawberry, Pepper, Copaiba Balsum, Coffee, Koboshi Bokubo Coconut mulberry, sesame seeds, sesame seeds, trash, saekane or binankazura or pine bushes, wheat, rice or rice bran, rice oil, cola acminata, cola bella, coloha, colombo, condurango, kombu, konnyaku, comfrey, sisal (sisal asa), saxima Button eel or cinnamon button bud or cinnamon ginseng, cherry (Ooshima cherry, Yamazakura, Oyama cherry, Edhigashi, Bean cherry, Miyaza cherry, Yoshino cherry, Takane cherry Cherry, Crested Cherry, Kohigan, Sugar Cherry, Kanzakura, Cherry, Pomegranate, Sasa, Sasanka, Sagiomodaka, Sweet Potato, Sugarcane, Sugar Beet, Sunflower Jujube, Saffron, Pomegranate, Savannah, Salmon Berry, Salvia Sangre de grad (croton), salamander, sanchinin carrot, sanshuyu, salamander, shea kon, shea (carite), cyanoki, shiitake mushroom, shion, jikitarisu, shikunshi, perilla or ajizo or chimmento or catamendizo, chitan, linden , Shiraringo, shimeji (hinshimeji, shakashimeji, hatake shimeji, oshiroi shimeji, beech shimeji, honjimeshi, shirotamogitake), shimotsuke, potato, Peonies, Shajin, Jasmine (Matsurika), Janohige, Shukukonka Missou, Shukushamitsu, Juzudama, Shiro, Zouzan Hydrangea, Shobu, Shozuk, Shirakashi, Shirogoricho, Shiroto Azuki, Shirobanairis (Nioiris), Shirobananthus Rubra, Ginkgo biloba, Cinnamon, Watermelon, Honeysuckle, Sorrel, Swimberry, Stevia, Strawberry, Psycho, Horsetail, Prunus, Plum, Prunus sylvestris, Larix larch, Prunus vulgaris, Prunus edulis, Hawthorn dandelion, Prunus edulis (Maroni) Pear, papaver, elder, juniper, yarrow (milfoil), cereal Rose, pearl butterfly, mistletoe, yellow mint or wild mint , Buckwheat, rice potato, radish, radish, soybean, daidai, takasaburo, takatodai, hawkfish, dark sweet cherries, hollyhock, hollyhock (thyme), tachidokoro (hikai), tachiyanagi, tamarind, onion, tamashiba, tanoki, tarouin Dandelion or white dandelion or mouko dandelion, danmaru, cherry, chigaya, chikutsuninjinjin, chicory, chankapiedra (Kidachikokankanso), Dendrobium, ginseng, ginseng, choreimaitake, chorogi, camellia, tsukuritake (mushrooms), camellia, camellia, tsumutsusa, tsuyuzuki, tsurumakudami, tuna, tsuruminjin, tsuwabuki, daiko, teuchiguru , Red pepper, red pepper, red pepper, red snapper (marigold), red corn, corn or corn, red potato, redhead or ginseng, groundnut, redberry, tocon, red pepper, red pepper, red pepper, tomato, red pepper Tragacanth, Triacanthus, Tormentilla, Doronoki, Trolley, Nigerian berry, Chinese yam or Yamanoimo, Nagai Kada ( Witcher bloom), naginata kouju, nazuna, rapeseed, jujube or vertical spider, jujube, jujube, naniwaibara, nabena, namoko, narukoyuri, peanut, nanten, namban karakushi, nigaki, nigimugi, kei or nikkei or keiyuni Elderberry, Garlic, Nurde, Green onion, Nemno or Nebu or Nebi or Nemkinoki or Zigokubana, Noahra, Nobara, Yarrow, Nodake, Novara, Peach, Palm, Pineapple, Hibiscus , Hackleberry, Jacobe, Hazel, Hasilikoro, Basil, Lotus, Parsley (Dutch Jelly), Hadakagi, Batata, Hachiku or Madake, Patchouli, Ha Duck, pearl barley (Yokuinin), Hanasuge, Banana, Hanabakka, Hanabishi (Shinshiri, Shishitsuri), Vanillabins, Duckweed, Pahalobobo, Hub, Paprika, Hagago or Mitsubaba Hamago, Hamasuge, Hamabishi, Hamaus, Hamabou, Hamabou Rose, Agaric (Agaric, White-faced Agaric, Ukimorinokasa), Haran, Pariurus (Amanita spp.), Parietalia, Balsamina (Villus serrata) Astragalus, Himawari, Pistachio, Beet, Hitotsuba, Hitotsuba Enishida, Hinata Taikozuchi, Hinoki, Hiba, Castor, Sunflower, Bell Pepper, Himezu, Himegama, Himematsutake, Kawariharatake, Hiromatsutake), Pimenta, Beakshi, Beakkyu, Ayu, Yellow-bellied Oyster, Hirohakinagusa, Biwa, Betel Nut, Fuyu-kazura, Fuuki, Futandanpopo, Fujibakama, Fuji-bean, Grape, Beech, Fuyu-Mina-Tsukutake, Brazilian Licorice Blackberry, Plum, Fruceraria, Blueberry (Prunus medusae), Prunes, Blond psyllium, Bundow, Hazelnut, Loofah, Safflower, Heneken, Belladonna, Berry, Pervianburg, Bentilla or or Duckweed, Boysenberry, Buffalo or Duckweed or Nendo Hahagigi Kokia, spinach, spinach, bowfish, spinach, physalis, physalis, bokeh, hosovana okera, hosowanakirinso, hosobarengi , Bodaige, Button, Buttonpi, Hop, Jojoba, Bordeaux, White berry, Hononiku, Honsekoku, Mizurutennanshaw, Maitake, Maou, Maca, Macadamia nuts, Macri, Magwa, Magnolia Splengeri, Mashua (Tamanowen Hallen, Kyukon Nasturtium), matatabi, matsukasa, pine, matsuhodo, matiko (cordon sillo), maryoram (hanaka mint), malvano jardin, mulberry, quince, mangosteen, manzanya (andesca mitsle), mansugulumi, mandarin, mannentake, pheasant, mishimako Mizuasagao, mizukakushi, misohagi, michiyanagi or niwayanagi, mitsugashiwa, honeybee, green mint, mimosa, mioga, miracle fruit, myrrh, mirobalan, mu Givaragiku, Mukuge, Mukunoki, Mukuroji, Munya, Murasaki, Murasakikibu or Omurasakikibu, Murasaki Maize, Murasaki Kinafuji, Mejiki, Mebogi, Melaroika, Melissa, Melilot, Melon, Moukomugi, Moso Mochi, Moe Moe Daiou, Peach, Palm, Morello Cherry, Morohaya, Yakawamurasaki, Yakuchi, Cornflower, Yacon, Yakkon, Yashabushi or Himeyashabushi or Obayayashabushi, Yachiyanagi, Yatsude, Misagi, Yagi , Pussy willow, dogwood willow, gold willow, koryanagi, unryu willow, miyagi willow, palm, willow, wow willow, tyrikkinu (Nagi, Fox Willow, Dorono), Yanagitade, Yabugarashi, Yabukouji, Yabu Tobacco, Porcupine, Porcupine, Eucalyptus, Porcupine, Eucalyptus, Yukinoshita, Yucca or Flavifolia, Yuzu, Lily, Yorigan, Larva, Lime, Lime, Lime (Clameliad), rakki or shallot, lavender, longan, agave (Aonu agave, fuchlin agave), ryokucha, apple, gentian, lubas or swabisimus, litchi, lettuce (chisha), red currant, lemon, lemongrass, forsythia or china Forsythia, forsythia, wax palm, locon (reed), logan berry, rosemary (mannenrou), rose hip (novara), wasabi, dressing It is.

  In addition, other seawaters such as sea salt, dried seawater, dead sea or Atlantic or Pacific seawater (sodium chloride, magnesium chloride, potassium chloride, etc.), sea mud or mud (fango), such as Sea mud or mud in various regions such as Italy, France, Germany, Eifel and Franceburg (Contained components: silicon dioxide, titanium dioxide, aluminum oxide, iron oxide, manganese oxide, sodium oxide, potassium oxide, magnesium oxide, calcium oxide) Strontium oxide, sodium, potassium, magnesium, calcium, chromium, iron, copper, nickel, zinc, lead, manganese, arsenic, water), saintoku stone and so on.

  As seaweeds, seaweed [green algae: Chlorella vulgaris, Chlorella pyrenoidosa, Chlorella ellipsoidia, Aonori (Usubaonori, Susiaoonori, Hianaonori), seaweed [Brown algae: Kombu Hosome Kombu, Mitsuishi Kombu), Wakame, Hirome, Aowakame, Giant Kelp (Macrocystis pirifera, Macrocystis integrofolia, Hiijiki, Hibamata), seaweed [Red algae: Hijirimen, Maxa (Tengusa), Nettle, cypress, prickly pear, caterpillar, yatabegusa, yui-kiri, striped primrose, crested beetle, spruce rhinoceros, crested rhinoceros, giraffe rhinoceros, ginseng giraffe, horned mackerel, plover Data, carrageen (Yahazutsunomata), Ezotsunomata, Togetsunomata, Hirakotoji, Kotojitsunomata, Suginori, Shikin'nori, Kainori, Ibotsunomata, Yareusubanori, Kagiusubanori, Sujiusubanori, Haiusubanori, Akamomijinori] and the like as a representative.

  In addition, other algae, for example, green algae (Chlamydomonas: Chlamydomonas, Akayukimo, Dunaliella: Dunaliella, Chlorococcus: Chlorococcus, Anemone: Quanomomo, Volbox: Ougenmawari, Volbox, Parmela, Yotsumeo, Aomido: Chrysanthemum, Aoumidro, Tirguimidro, Hibidoro: Hibidoro, Aosa: Anaaaosa, Amiaosa, Nagaaosa, Kawanori: Kawanori, Friccella, Shiogusa Magama genus: Magamata, Iwagata: Fusaikawa, Surichogi, Heraiwata, Kurokita, Hanemo, Genus: Mill, Chromel, Sakibuchimil, Nagamil, Hihi Mil, Casanori genus: Casanori, Jusmo genus: Futjusmo, Tamajusmo, Mizojuzumo, Mika ヅ kimo, Korekaete, Tsutsumimo genus: Kyukougusa, Homogusa genus: Human esca Sumiremo: Sumiremo, Hoshimamidro, Fushinashimidoro etc.).

  Cyanobacteria (Suizenjinori: Suizinori, Aoko, Nenjumo: Kawatake, Ishijelly, Hassai, Yuremo, Rasenmo (Spirulina): Spirulina, Trichodesmium (Iaciasio), etc.

  Brown alga Sanadagusa: Sanadagusa, Fukurimamiji, Commongusa: Commongusa, Yahazugusa: Ezoyahaz, Yahazugusa, Uraboshiyahaz, Jigamusa: Jigmygusa, Umichiwagusa, Umamisakugakua, Hakusou : Navarimo, Chasomen genus: Motsuki Chasomen, Matsumo genus: Matsumo, Nagamatsumo genus: Nagamatsumo, Okinawa mozuku: Okinawa mozuku, fake Tomozuku: Niseft Mozuku, Futomozuku: Futomozuku, Ishimozuku: Ishimozuku, Kuromo: Kuromo, Nisemozuku: Nisemozuku, Mozuku: Mozuku, Ishige: Ishige, Iroro, Ichimosa: Ichimegasa Umibosu, Urushigusu: Urushigusa, Keurushigusa, Tobaccogusa, Composita: Composita, Haberodomo: Haberodoki, Havanori: Habanori, Habanori: Habanori, Commonbukuro, Ezobukuro, Ezobukuro Chishima fukuronori genus: Chishima fukuronori, Kagomenori genus: Kagomenori, Muraridori genus: Murachidori, shark genus: shark zusa, genus genus: lobster, genus genus: yokojimamanori, Ganoderma genus: cynomolgus, fennel spider: fennel spider, vine genus: turmo, turtle genus: sea turtle, scorpion genus: sujime, misji kumbu genus: misji kumbu, atsuba misji kumbu, kumbu genus: tsutsugara kumbu, oyster kumbu, onikombu, gakonbubu Barracuda, Trollocombu: Trollocombu, Antokume: Antokume, Kajime: Kajime, Tsuruarame, Kurome, Kikuishikombu: Kikuishicombu, Nejikcombu: Nejicombu, Kuroshiome: Kuroshiome, Nekoshikonbu, Aramei Genus: Ainuwakame, Chigaiso, Oniwakame Ezoi Shige: Ezoi Shige, Yabane Moku: Yabane Moku, Rappa Moku: Rappa Moku, Joromoku: Ugano Moku, Jo Lomoku, Hiemoku, Honda Walla: Tamanashimoku, Isomoku, Nagashimamoku, Akamoku, Shidamoku, Honda Walla, Nejimoku, Narasamo, Mametawala, Tatsukuri, Yatsumata Moku, Umitora no Moku, Fushishimoku, Mohmokumoku, Hahamokumoku ), Genus Ukimo: Ouki, genus Burukimo: burukimo, genus genus: mosquito mono).

  Red algae Genus: Sea urchins, Tsukumonori, Anemone crickets, Astragalus, Amaranthus, Amaranthus, Agaricata Genus: Tamaitadaki, Kaikekenori Genus: Kaginori, Kaikekenori, Tengusa: Himetengususa, Hytengususa, Oobusa, Nambugu , Kohira, Yohira, Kinukusa, Hibirodo: Hibirodo, Himebiro, Isomumedo: Isommedo, Aedes: Rhizome, Ryumons: Ryumon, Ranunculaceae, Nisekare Naminohana: Hosobanaminohana, Naminohana, Sangomodoki: Ragaramomodoki, Shiogusagoromo: Shiogusagoromo, Iwanokawa: Etsukiiwanawa, Kinokawa: Kinokawa, Kanonote, Sangori Scarlet, cherry blossom, Nikumukade, Tambanori, Tsurutsuru, Isonohana: Nurakusa, Cronouraxa, Oumkadeno , Hirakintoki spp. Mafunori, Karekigusa: Karekigusa, Tosakamodoki: Hosobanotosakamodoki, Hirohatosakamodoki, Yatsudegatatosakamodoki, Kurotosakamodoki, Nezashinotosakamodoki, Kinuhasada, Ezotosaka , Anopheles genus: Honoo, genus genus: genus genus, Usuginu, genus Anemone: genus genus, genus Venus: genus Venice, genus Suskakebeni: Skakebeni, Okamuragusa: Yamadagusa, Mirin-genus: Mirin, Hosobamyrin, Tosakanori: Kikutosaka, Ezonameshi: Ezonameshi, Isomokka: Isomokka, Yukari: Yukari, Hosoyukari, Ibaranori: Phellinus genus, Isodantsu: Isodantsu, Atsubanori: Atsubanori, Ogonori: Ogonori, Tsurushiramo, Shiramo, Oonogori, Mizokonori, Birch, Amanita spp. , Genus genus: cypress, genus: cypress, cygnus, spinach, spinach genus: spinach, cedar genus: staghorn, hosoibono Li, Novonori, Black-tailed genus: Black-crowned dragon, Red-billed genus: Red-billed pea, Red-billed genus: Red-billed crocodile, Red-tailed moth : Hanaeda, Hirataka goat genus: Hirataka goat, Dulse genus: Darus, Masagobari, Anadalus, Uebagsa genus: Uebagusa, Benifukuronori: Benifukuronori, Fushitsunagi genus: Fusunagi, Himefusunagi, Hirohasunahi, Tsukiwiso : Igis, Keigis, Harigis, Hanegis, Amixa, Egonori genus: Egonori, Fuyugisu, Saeda genus: Saeda, Chilemomoji: Chirimomiji, Kono Noriaceae: Habutaenori, Conohanori, Suzuronori, Usbeni: Usbeni, Hasujiginu: Hasujiginu, Nagakonohanori: Nagakononohanori, Sugiginu: Sugiginu, Abasbasginu, Heiusbanova , Ayanishiki: Ayanishiki, Aaginu: Ayaginu, Dadia: Enasidadia, Shimadadia: Isohagi, Shimadadia, Dajimodoki: Daimodomoki, Engussa , Plywood, moss willow, sasabayagi nori, sozo: Kurosozo, kubsozo, nesozo, sozonohana, sedge genus: sedge, sage Cozanemo: Kozanemo, Isomurasaki, Hosokozanemo, Himegoke: Himegoke, Kurohimegoke, Hyodosigus: Chrysanthemum, Hyodosigusa, Usubahiodosi, Isomegusa: Isomegusa, Sugina Fuso Sakisawiri, Kawamoku, Kawamozuku, Aokawa Mozuku, Himekawa Mozuku, Ideyugogome: Ideyugogome, Okichimozuku, Okichimozuku, Engussa, Chinomo, Chinozurimo, Chisujinori, etc.)

  Axal algae (Shajikumo spp., Shiratamamo spp., Hoshitsurimo spp .: Hoshitsurimo, Rikunotamus spp., Flask spp .: Hime flaskmo, Chaboflaskmo, Tripera spp., Etc.), Yellow algae (Hikarimo spp .: Hikarimo, etc.), etc.

  In addition, animal-derived materials include poultry extract, bovine, porcine or human placenta extract, porcine or bovine stomach, duodenum or intestinal extract or its degradation product, porcine or bovine spleen extract Or a degradation product thereof, an extract of porcine or bovine brain tissue, a water-soluble collagen, a collagen derivative such as acylated collagen, a collagen hydrolyzate, elastin, an elastin hydrolyzate, a water-soluble elastin derivative, keratin and a degradation product thereof, or Derivatives thereof, silk proteins and degradation products thereof or derivatives thereof, porcine or bovine blood cell protein degradation products (globin peptides), porcine or bovine hemoglobin degradation products (hemin, hematin, heme, protoheme, heme iron, etc.), milk, Casein and its degradation products or their derivatives, skim milk powder and their degradation products or their derivatives, lactoferrin or their degradation products, chicken Component, fish meat decomposition products such as.

  (14) Microbial culture metabolite yeast metabolite, yeast extract, natto metabolite, natto extract, rice fermented extract, rice bran fermented extract, Euglena extract, lactic acid fermented milk or trehalose or its derivatives Such.

  (15) α-hydroxy acids glycolic acid, citric acid, malic acid, tartaric acid, lactic acid and the like.

  (16) Inorganic pigments silicic anhydride, magnesium silicate, talc, kaolin, bentonite, mica, titanium mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, calcium carbonate, magnesium carbonate, yellow iron oxide, Bengala, black iron oxide, gunjo, chromium oxide, chromium hydroxide, carbon black, calamine, etc.

  (17) UV absorber / blocker benzophenone derivatives (2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid sodium salt, dihydroxy Dimethoxybenzophenone, dihydroxydimethoxybenzophenone-sodium sulfonate, 2,4-dihydroxybenzophenone, tetrahydroxybenzophenone, etc.), p-aminobenzoic acid derivatives (paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, paradimethylaminobenzoic acid) Amyl, octyl paradimethylaminobenzoate, etc.), methoxycinnamate derivatives (ethyl paramethoxycinnamate, isopropyl paramethoxycinnamate, paramethoxycinnamate) Cutyl, 2-methoxyethyl paramethoxycinnamate, sodium paramethoxycinnamate, potassium paramethoxycinnamate, diparamethoxycinnamate mono-2-ethylhexanoate glyceryl, etc.), salicylic acid derivatives (octyl salicylate, salicylphenyl, homomenthyl salicylate, dipropylene glycol salicylate) , Ethylene glycol salicylate, myristyl salicylate, methyl salicylate, etc.), anthranilic acid derivatives (such as methyl anthranilate), urocanic acid derivatives (such as urocanic acid, ethyl urocanate), coumarin derivatives, amino acid compounds, benzotriazole derivatives, tetrazole derivatives, Imidazoline derivatives, pyrimidine derivatives, dioxane derivatives, camphor derivatives, furan derivatives, pyrone derivatives, nucleic acid derivatives, Totoin derivatives, nicotinic acid derivatives, vitamin B6 derivatives, umbelliferone, esculin, benzyl cinnamate, cinoxalate, oxybenzone, dioxybenzone, octabenzone, soribenzone, benzoresorcinol, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, neoheliopan, Escalol, zinc oxide, talc, kaolin, etc.

  (18) Whitening agent: p-aminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound, benzotriazole derivative, tetrazole derivative, imidazoline derivative, pyrimidine derivative, dioxane derivative, camphor derivative, furan derivative, Pyrone derivative, nucleic acid derivative, allantoin derivative, nicotinic acid derivative, vitamin C or its derivative (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), vitamin E or its derivative, kojic acid or its derivative, naphthol or its derivative Naphthol glycosides or derivatives thereof, oxybenzone, benzophenone, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, placenta extract, ellagic acid, lucinol and the like.

  (19) Tyrosinase activity inhibitor: Vitamin C or a derivative thereof (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), hydroquinone or a derivative thereof (hydroquinone benzyl ether, etc.), kojic acid or a derivative thereof, naphthol or a derivative thereof, Naphthol glycoside or derivative thereof, vitamin E or derivative thereof, N-acetyltyrosine or derivative thereof, glutathione, hydrogen peroxide, zinc peroxide, placenta extract, ellagic acid, arbutin, lucinol, silk extract, plant extract (camomile , Mulberry, touki, firewood, clara, mugwort, honeysuckle, yellowfin, dolphin, pine-hod, pearl barley, nettle, hop, hawthorn, eucalyptus, yarrow, altea, keihi, mankei, hamamelis, yamagwa, Lifegrass, bellflower, toshishi, sequel, shotfish, mahuang, senkyu, dokatsu, psycho, bowfish, kingfisher, peony, peony, peony, genus shochu, kudzu, licorice, quintuplet, aloe, shouma, safflower, green tea, tea, Asen).

  (20) Melanin pigment reduction / decomposition substance: phenylmercury hexachlorophene, mercuric oxide, mercuric chloride, hydrogen peroxide, zinc peroxide, hydroquinone or its derivative (hydroquinone benzyl ether), vitamin C or its derivative ( Vitamin C phosphate magnesium salt, vitamin C glucoside), naphthol or a derivative thereof, naphthol glycoside or a derivative thereof, and the like.

  (21) Turnover promoting action / cell activator: hydroquinone, lactic acid bacteria extract, placenta extract, ganoderma extract, vitamin A, vitamin E, allantoin, spleen extract, thymus extract, yeast extract, fermented milk extract, plant extract (aloe , Ogon, Horsetail, Gentian, Burdock, Sikon, Carrot, Clam, Hop, Yokuinin, Odorikosou, Semburi, Toki, Ginseng, Achacha, Hypericum, Cucumber, Pleurotus, Rosemary, Parsley).

  (22) Astringent: succinic acid, allantoin, zinc chloride, zinc sulfate, zinc oxide, calamine, zinc p-phenolsulfonate, potassium aluminum sulfate, resorcin, ferric chloride, tannic acid (including catechin compound) and the like.

  (23) Active oxygen scavenger: SOD, catalase, glutathione peroxidase and the like.

  (24) Antioxidants: Vitamin C or a salt thereof, stearic acid ester, vitamin E or a derivative thereof, nordihydrogua ceretenoic acid, butylhydroxytoluene (BHT), butylhydroxyanisole (BHA), hydroxytyrosol, parahydroxy Anisole, propyl gallate, sesamol, sesamorin, gossypol, etc.

  (25) Lipid peroxide production inhibitor: β-carotene, plant extract (sesame culture cells, hamcha, hypericum, clams, clove, melissa, birch, birch, sage, rosemary, nanjimi, agetsu, ginkgo, green tea) .

  (26) Anti-inflammatory agents: ictamol, indomethacin, kaolin, salicylic acid, sodium salicylate, methyl salicylate, acetylsalicylic acid, diphenhydramine hydrochloride, d-camphor, dl-camphor, hydrocortisone, guaiazulene, camazulene, chlorpheniramine maleate, glycyrrhizic acid or Its salt, glycyrrhetinic acid or its salt, licorice extract, sicon extract, age extract, allantoin, etc.

  (27) Antibacterial / bactericidal / disinfectant: Acrinol, sulfur, calcium gluconate, chlorhexidine gluconate, sulfamine, mercurochrome, lactoferrin or hydrolyzate thereof, alkyldiaminoethylglycine chloride solution, triclosan, sodium hypochlorite, chloramine T , Salicy powder, iodine compound, iodoform, sorbic acid or its salt, salicylic acid, dehydroacetic acid, parahydroxybenzoic acid esters, undecylenic acid, thiamine lauryl sulfate, thiamine lauryl nitrate, phenol, cresol, p-chlorophenol, p -Chloro-m-xylenol, p-chloro-m-cresol, thymol, phenethyl alcohol, o-phenylphenol, Irgasan CH3565, halocarban, hexachlorophene, chlorohexyl , Ethanol, methanol, isopropyl alcohol, benzyl alcohol, ethylene glycol, propylene glycol, phenoxyethanol, chlorobutanol, isopropylmethylphenol, nonionic surfactant (polyoxyethylene lauryl ether, polyoxyethylene nonylphenyl ether, polyoxyethylene octyl Phenyl ether, etc.), amphoteric surfactants, anionic surfactants (sodium lauryl sulfate, potassium lauroyl sarcosine, etc.), cationic surfactants (cetyltrimethylammonium bromide, benzalkonium chloride, benzethonium chloride, methylrosaniline chloride), formaldehyde, Hexamine, brilliant green, malachite green, crystal violet, jamal, photosensitizer 10 No. 1, Photosensitive Element 201, Photosensitive Element 401, N-long chain acyl basic amino acid derivatives and acid addition salts thereof, zinc oxide, hinokitiol, kudin and the like.

  (28) Moisturizer: glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, hyaluronic acid or its salt, polyethylene glycol, chondroitin sulfate or its salt, water-soluble chitin or chitosan derivative, pyrrolidone carboxylic acid or its salt , Sodium lactate, mini sasanishiki extract, natto bacteria metabolite, natto extract and so on.

  (29) Elastase activity inhibitors: diisopropyl fluorophosphate, plant extracts (Ogon, Hypericum, Clara, Mulberry leaves, Keihi, Gennosho, Comfrey, Sage, Elderberry, Bodaige, Buttonpi), seaweed extract and the like.

  (30) Hair preparation: selenium disulfide, alkylisoquinolinium bromide solution, zinc pyrithione, biphenamine, thianthol, castari tincture, pepper tincture, red pepper tincture, quinine hydrochloride, strong aqueous ammonia, potassium bromate, sodium bromate, Such as thioglycolic acid.

  (31) Antiandrogens: follicular hormones (estrone, estradiol, ethinyl estradiol, etc.), isoflavones, oxendrone, etc.

  (32) Peripheral vascular blood flow promoter: Vitamin E or its derivatives, assembly extract, garlic extract, carrot extract, aloe extract, gentian extract, toki extract, cephalanthin, carpronium chloride, minoxidil and the like.

  (33) Local stimulants: chili pepper tincture, capsaicin, capsaicin glycoside, nonyl acid vanillamide, cantalis tincture, ginger tincture, peppermint oil, l-menthol, camphor, benzyl nicotinate and the like.

  (34) Metabolic active agents: Photosensitive element 301, hinokitiol, pantothenic acid or derivatives thereof, allantoin, placenta extract, biotin, pentadecanoic acid glyceride and the like.

  (35) Antiseborrheic agents: pyridoxine or derivatives thereof, sulfur, vitamin B6 and the like.

  (36) Keratolytic agents: resorcin, salicylic acid, lactic acid and the like.

  (37) Oxidizing agent: hydrogen peroxide, sodium persulfate, ammonium persulfate, sodium perborate, urea peroxide, sodium percarbonate, sodium tripolyphosphate, sodium bromate, potassium bromate, sodium pyrophosphate Sodium orthophosphate, sodium silicate hydrogen peroxide adduct, sodium sulfate sodium chloride hydrogen peroxide adduct, β-tyrosinase enzyme solution, mushroom extract, etc.

  (38) Hair remover: inorganic reducing agent such as strontium sulfate, sodium sulfide, barium sulfide, calcium sulfide, thioglycolic acid or its salts (calcium thioglycolate, sodium thioglycolate, lithium thioglycolate, thioglycolic acid Magnesium, strontium thioglycolate) and the like.

  (39) Hair swelling agent: ethanolamine, urea, guanidine and the like.

  (40) Bath sensation agent: sodium bicarbonate, sodium carbonate, sodium sesquicarbonate, sodium sulfate, dry sodium sulfate, anhydrous sodium sulfate, anhydrous silicic acid, calcium silicate, etc.

  (41) Dye agent: 5-aminoorthocresol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol, 1-amino-4-methylaminoanthraquinone, 3,3′-iminodiphenol, hydrochloric acid 2,4-diaminophenoxyethanol, 2,4-diaminophenol hydrochloride, toluene-2,5-diamine hydrochloride, nitroparaphenylenediamine hydrochloride, paraphenylenediamine hydrochloride, N-phenylparaphenylenediamine hydrochloride, metaphenylenediamine hydrochloride, orthoamino Phenol, N-phenylparaphenylenediamine acetate, 1,4-diaminoanthraquinone, 2,6-diaminopyridine, 1,5-dihydroxynaphthalene, toluene-2,5-diamine, toluene-3,4-diamine, nitroparaphenylene Diamine, paraaminophenol, Lanitroorthophenylenediamine, paraphenylenediamine, paramethylaminophenol, picramic acid, sodium picramate, N, N′-bis (4-aminophenyl) -2,5-diamino-1,4-quinonediimine, 5- ( 2-hydroxyethylamino) -2-methylphenol, N-phenylparaphenylenediamine, metaaminophenol, metaphenylenediamine, 5-aminoorcresol sulfate, 2-amino-5-nitrophenol sulfate, orthoaminophenol sulfate, sulfuric acid Orthochloroparaphenylenediamine, 4,4'-diaminodiphenylamine sulfate, 2,4-diaminophenol sulfate, toluene-2,5-diamine sulfate, nitroparaphenylenediamine sulfate, paraaminophenol sulfate, paranitroorthophenylene sulfate Diamine, Sulfated paranitrometaphenylenediamine, Sulfated paraphenylenediamine, Sulfated paramethylaminophenol, Sulfated metaaminophenol, Sulfated metaphenylenediamine, Catechol, Diphenylamine, α-Naphthol, Hydroquinone, Pyrogallol, Phloroglucin, Gallic acid, Resorcin, Tannin Acid, sodium 2-hydroxy-5-nitro-2 ′, 4′-diaminoazobenzene-5′-sulfonate, hematein and the like.

  (42) Fragrance: Natural animal fragrances such as musk, civet, castorium, ambergris, anise essential oil, angelica essential oil, ylang ylang essential oil, iris essential oil, fennel essential oil, orange essential oil, cananga essential oil, caraway essential oil, cardamom essential oil, guayakwood essential oil , Cumin essential oil, black letter essential oil, cinnamon essential oil, cinnamon essential oil, geranium essential oil, copaiba balsam essential oil, coriandel essential oil, perilla essential oil, cedarwood essential oil, citronella essential oil, jasmine essential oil, gingergrass essential oil, cedar essential oil, spearmint essential oil, western peppermint essential oil , Otsuka perfume essential oil, tuberose essential oil, clove essential oil, orange flower essential oil, winter green essential oil, trout balsam essential oil, buttery essential oil, rose essential oil, palmarosa essential oil, persimmon essential oil, hiba essential oil, sandalwood essential oil, petitgren essential oil, bay essential oil, vetiva essential oil, Bergamo Tomato essential oil, Peruvian balsam essential oil, Boad rose essential oil, melamine essential oil, mandarin essential oil, eucalyptus essential oil, lime essential oil, lavender essential oil, linaloe essential oil, lemongrass essential oil, lemon essential oil, rosemary essential oil, Japanese mint mint essential oil, etc. . Synthetic perfume ingredients include aliphatic hydrocarbons, terpene hydrocarbons, aromatic hydrocarbons and other hydrocarbons, aliphatic alcohols, terpene alcohols, aromatic alcohols and other alcohols, aliphatic ethers, aromatic ethers and other ethers Oxides, aliphatic oxides, terpene oxides, aliphatic aldehydes, terpene aldehydes, hydrogenated aromatic aldehydes, aldehydes such as thioaldehydes, aromatic aldehydes, aliphatic ketones, terpene ketones, hydrogenated aromatics Ketones such as aromatic ketones, aliphatic cyclic ketones, non-benzene aromatic ketones, aromatic ketones, acetals, ketals, phenols, phenol ethers, fatty acids, terpene carboxylic acids, hydrogenated aromatic carboxylic acids, Acids such as aromatic carboxylic acids, acid amides, aliphatic lactones Lactones such as cyclic lactones, terpene lactones, hydrogenated aromatic lactones, aromatic lactones, aliphatic esters, furan carboxylic acid esters, aliphatic cyclic carboxylic acid esters, esters such as aromatic carboxylic acid esters, Nitrogen-containing compounds such as nitromusks, nitriles, amines, pyridines, quinolines, pyrrole and indole. More specific examples of synthetic fragrances include, for example, 1996 published by Chemical Industry Daily, Motoichi Into (Synthetic fragrance chemistry and product knowledge), 1969, by Stefan Arcamder (Perfume and Flavor Chemicals <Perfume and) Flavors described in Flavor Chemicals>) and the like can be suitably used. The main fragrances are shown below. Aldehyde C6-C12, anisaldehyde, acetal R, acetophenone, acetyl cedrene, adoxal, allyl amyl glycolate, allyl cyclohexane propionate, alpha damascon, beta damascon, delta damascon, ambrette lid, ambroxan, amyl Cinnamic aldehyde, amyl cinnamic aldehyde dimethyl acetal, amyl valericate, amyl salicylate, isoamyl acetate, isoamyl salicylate, uranium thiol, acetyl urgenol, bacdanol, benzyl acetate, benzyl alcohol, benzyl salicylate, bergamyl acetate, bornyl acetate , Butyl butyrate, para tertiary butyl cyclohexanol, para tertiary butyl Chlohexyl acetate, ortho-tertiary butylcyclohexanol, benzaldehyde, benzyl formate, potassium olefin, cashomeran, carvone, cedro amber, cedryl acetate, cedrol, ceristolide, cinnamic alcohol, cinnamaldehyde, cis jasmon, citral, citral Dimethyl acetal, citrusal, citronellol, citronellyl acetate, citronellyl formate, citronellyl nitrile, cyclaset, cyclamenaldehyde, cyclaprop, caron, coumarin, cinnamyl acetate, delta C6-C13 lactone, dimethylbenzyl carbinol, dihydrojasmon , Dihydrolinalol, dihydromyrcenol, dimethol, dimyrcetol, di Enyl oxide, ethyl vanillin, eugenol, fluitate, fenthyl alcohol, phenylethylphenyl cetate, galakisolid, gamma C6-C13 lactone, geraniol, geranyl acetate, geranyl formate, geranyl nitrile, hedion, helional, heliotropin, cis-3- Hexenol, cis-3-hexenyl acetate, cis-3-hexyne neil salicylate, hexyl cinnamic aldehyde, hexyl salicylate, hyacinth dimethyl acetal, hydrotropic alcohol, hydroxy citronellal, indole, innon, isobornyl acetate, Isocyclocitral, iso-E super, isoyugenol, isononyl acetate, isobutyl quinoline, jasmar , Jasmolactone, jasmofilan, coabon, ligustral, lyial, lime oxide, limonene, linalool, linalool oxide, linalyl acetate and the like.

  (43) Dye: Colorant Red Cabbage Dye, Red Rice Dye, Akane Dye, Anato Dye, Ikumi Dye, Turmeric Dye, Enju Dye, Krill Dye, Amber Dye, Caramel, Gold, Silver, Gardenia Dye, Corn Dye, Onion Dye , Tamarind pigment, spirulina pigment, buckwheat whole plant pigment, cherry pigment, laver pigment, hibiscus pigment, grape juice pigment, marigold pigment, purple potato pigment, purple yam pigment, lac pigment, rutin etc.

  Others, hormones, sequestering agents, pH adjusting agents, chelating agents, antiseptic and antibacterial agents, cooling agents, stabilizers, emulsifiers, animal / plant proteins or their degradation products, animal / plant polysaccharides or the like Degradation products, animal / plant glycoproteins or their degradation products, anti-inflammatory agents / antiallergic agents, wound treatment agents, foams / foaming agents, thickeners, oral preparations, deodorants / deodorants, enzymes, etc. In combination with these, various additive or synergistic effects can be expected.

  The cosmetic composition, bath preparation composition, and detergent composition of the present invention are liquid, emulsion, paste, gel, powder (powder), granule, pellet, stick, solid, etc., respectively. It may be provided as any form.

  Cosmetic compositions include lotion, milky lotion, cream, oil, ointment, pack, lip, lipstick, foundation, eyeliner, blusher, mascara, eye shadow, nail polish / pedicure, nail coating, nail coating removal Agent, shaving agent, shampoo, rinse, hair treatment, hair tonic, hair spray, hair cream, hair lotion, hair conditioner, hair restorer, permanent liquid, hair dye, hand soap / body soap, toothpaste, mouthwash , Facial cleansers and soaps.

  The bath agent composition is generally used by pouring in hot water at the time of bathing, but in some cases, it may be effective to use it in hot water. The form of the bath agent composition may be any of liquid, powder, granule, solid and the like. In the case of a powder, granule or solid, the moisturizing plant extract of the present invention can be produced by spraying and drying in a liquid state without drying.

  Examples of the detergent composition include daily kitchen detergent, bathroom, basin or toilet detergent, glass cleaner, glasses / contact lens cleaner, car cleaner, and building material cleaner.

  In addition, it can be impregnated in sanitary goods, wet type tissue paper, non-woven fabric, paper towel, cotton and the like.

  In the cosmetic composition and detergent composition of the present invention, the moisturizing plant extract contains about 0.001 to 5% by weight, preferably about 0.01 to 1% by weight, as a dry extract. And good effects can be obtained. Moreover, in a bath agent composition, it can be used at 0.001-99 mass%, Preferably when it contains 0.1-30 mass%, usability is good and a favorable result is obtained. The amount used in one batch may be set so that the concentration in the bath water when actually used is 0.0001 to 0.01% by weight, preferably about 0.0005 to 0.005% by weight.

  The production examples, test examples, and formulation examples will be described below, but the present invention is not limited thereto.

[Example 1] (Production Example 1)
500 ml of water was added to each mixture of Kojito, that is, 4 g of peony, 4 g of peony, 4 g of peony, 4 g of peony, 4 g of button pie, 1.5 g of licorice and 1 g of pepper and refluxed for 1 hour. Next, this was filtered to obtain an extract, and further dried to obtain 6.0 g of a brown powder.

[Example 2] (Production Example 2)
500 L of ethanol was added to each constituent crude drug of Kojito, namely 4 kg of peony, 4 kg of peony, 4 kg of peony, 4 kg of peony, 4 kg of button pi, 1.5 kg of licorice and 1 kg of syrup, and extracted by immersion overnight. Next, this was filtered to obtain an extract, and further dried to obtain 6.0 kg of a light brown powder.

Evaluation result of skin irritation Safety test Evaluation of skin irritation In order to evaluate the skin irritation of the external preparation, cosmetics, bath preparation, and moisturizing plant extract for detergent composition of the present invention, healthy subjects (24- A 58-year-old male and female) patch test with 43 monitors.
(Sample) A product obtained by swelling the moisturizing plant extract obtained in Production Examples 1 and 2 with purified water.
(Method) For each sample, the skin sensitization test tape “Fin Chamber” (manufactured by Taisho Pharmaceutical Co., Ltd.) was used to make a determination by applying occlusion for 24 hours on the subject's flexor side and the inner side of the forehead. That is, the sample was removed at the time when 24 hours had passed after the application, and after 1 hour, the skin condition was observed and judged, and the average value was shown in Table 1.
(Criteria) Judgment was performed according to the following criteria.
(+) Positive: Those with erythema.
(±) false positive: Minor erythema or suspected erythema.
(-) Negative: No reaction is observed.
It was.

  From Table 1, the skin irritation was not recognized by the moisturizing plant extract for cosmetics, bath preparations and detergent compositions according to the present invention.

Example of moisture absorption test
In order to evaluate the moisturizing properties of the external preparations, cosmetics, bathing agents, and detergent compositions for the present invention, the moisture retention ability was measured at a relative humidity of 32%. That is, 1 g of various extracts was precisely taken in a weighing bottle and dried for 12 hours with a desiccator. After measuring the weight of the weighing bottle again, it was left in each desiccator with a relative humidity of 32% kept in advance at 30 ° C., and the weight was measured over time to obtain the amount of moisture absorption (%) up to 8 hours later. It was shown in 1.

  From FIG. 1, it was found that the moisturizing plant extract according to the present invention exceeded the hygroscopic ability of each constituent crude drug with the same solid content concentration, and the skin moisturizing property was improved. Therefore, it was recognized that the moisturizing plant extract of the present invention is effective in improving rough skin. Moreover, it was shown that a synergistic effect is acquired by the combination of different plant extracts.

  Production of various external preparation compositions Various external preparation compositions according to the present invention were produced. Although the formulation example is shown below, this invention is not limited to these. All formulation examples are given in parts by weight. All the moisturizing plant extracts of the present invention were produced in Production Example 1.

[Example 3]
According to Formulation Example 1, a cosmetic base in which purified water is mixed with moisturizers such as 1,3-butylene glycol and glycerin, skin nutrients such as oleyl alcohol, and preservatives and ethyl alcohol in which a fragrance is dissolved at room temperature. In the preparation, 0.3% of the moisturizing plant extract of the present invention was blended to prepare the lotion of the present invention.

Formulation Example 1 (Lotion)
1,3-butylene glycol 6.0
Glycerin 4.0
Oleyl alcohol 0.1
Polyoxyethylene monolaurate (20)
Sorbitan 0.5
Polyoxyethylene (15) lauryl ether 0.5
Ethyl alcohol 10.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 78.4
Total 100.0

[Example 4]
In accordance with Formulation Example 2, prepared was prepared by blending purified water with a moisturizing agent such as 1,3-butylene glycol and glycerin as the aqueous phase, and 0.3% of the moisturizing plant extract of the present invention was blended therein. . As the oil phase part, a solid oil component such as beeswax, cetyl alcohol and petrolatum, a liquid oil component such as squalane, an oily component such as an antiseptic and a surfactant, and the mixture heated to about 80 ° C. were prepared. A thickener such as quince seed was added to the aqueous phase heated to about 80 ° C., and the oil phase was gradually added and emulsified while stirring with a homomixer to obtain the emulsion of the present invention.

Formulation example 2 (milky lotion)
Cetyl alcohol 1.0
Beeslow 0.5
Octyldodecanol 2.0
Vaseline 2.0
Squalane 6.0
Ethyl alcohol 5.0
Glycerin 4.0
1,3-butylene glycol 4.0
Polyethylene glycol monooleate (10) 1.0
Lipophilic glyceryl monostearate 1.0
Quince Seed (Quince Seed) 1.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 72.0
Total 100.0

[Example 5]
In accordance with Formulation Example 3, as the water phase part, purified water containing a moisturizing agent such as 1,3-butylene glycol and polyethylene glycol 1500 is prepared, and the moisturizing plant extract of the present invention is added to 0.3%. % Blended. As the oil phase part, a solid oil component such as stearic acid, stearyl alcohol and hydrogenated lanolin, a liquid oil component such as squalane and octyldodecanol, and oily components such as preservatives and surfactants were prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and emulsified to obtain the cream of the present invention.

Formulation Example 3 (Cream)
Stearic acid 2.0
Stearyl alcohol 6.0
Hydrogenated lanolin 4.0
Squalane 9.0
Octyldodecanol 10.0
1,3-butylene glycol 6.0
Polyethylene glycol 1500 4.0
Polyoxyethylene (25) cetyl ether 3.0
Glycerol monostearate 2.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 53.5
Total 100.0

[Example 6]
In accordance with Formulation Example 4, moisturizing agents such as 1,3 butylene glycol and glycerin were added to purified water, and 0.3% of the moisturizing plant extract of the present invention was added thereto. This is heated to 70 to 80 ° C., a thickener such as carboxymethyl cellulose, a film agent such as polyvinyl alcohol is added and dissolved by stirring, and a solution obtained by dissolving a preservative, a surfactant, etc. in ethyl alcohol is added. Solubilized to obtain a pack of the present invention.

Formulation example 4 (pack)
Polyvinyl alcohol 15.0
Carboxymethylcellulose 5.0
1,3-butylene glycol 4.0
Glycerin 1.0
Ethyl alcohol 12.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Polyoxyethylene oleyl ether 0.5
Purified water 62.0
Total 100.0

[Example 7]
According to the formulation example 5, the water phase part mix | blended moisturizing agents, such as 1, 3- butylene glycol, with the purified water, and mix | blended 0.5% of the moisturizing plant extract of this invention. The oil phase part is prepared by mixing preservatives and surfactants with solid oils such as beeswax, paraffin wax, microcrystalline wax, higher fatty acids, semi-solids such as petrolatum and lanolin, and liquid oils such as liquid paraffin. Dissolved by heating. Next, the water phase part was heated and dissolved at 80 ° C., and the oil phase part heated to the same degree was gradually added and emulsified with stirring to obtain the ointment of the present invention. The external antipruritic agent in the present invention is arbitrarily blended into the external composition base, but when the external composition is composed of an aqueous phase and an oil phase, it is usually blended in the aqueous phase part. It is preferable.

Formulation Example 5 (ointment)
Beeswax 1.0
Paraffin wax 2.5
Microcrystalline wax 0.5
Stearic acid 2.0
Cetyl alcohol 1.0
Behenyl alcohol 3.0
Polyoxyethylene monostearate (20)
Sorbitan 1.0
Tetraoleic acid polyoxyethylene (60)
Sorbitan 1.0
Self-emulsifying glyceryl monostearate 1.5
Liquid paraffin 5.0
Lanolin 1.0
Vaseline 4.0
1,3-butylene glycol 5.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 70.8
Total 100.0

[Example 8]
In accordance with Formulation Example 6, purified water containing a humectant such as glycerin or urea was prepared as an aqueous phase part, and 0.5% of the moisturizing plant extract of the present invention was added thereto. As the oil phase part, a mixture of solid oils such as cetanol and petrolatum, liquid oils such as liquid paraffin, tocopherol acetate and vitamin D, preservatives, surfactants and other oily components was prepared. When the water phase part was gradually heated and reached about 80 ° C., the oil phase part heated to substantially the same temperature was added little by little and emulsified to obtain the hand cream of the present invention.

Formulation Example 6 (hand cream)
Cetanol 4.0
Vaseline 2.0
Liquid paraffin 10.0
Tocopherol acetate 0.1
Vitamin D 0.1
Urea 2.0
Glycerin 20.0
Polyoxyethylene (60)
Glycerol isostearate 2.5
Glycerol monostearate 1.5
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 57.1
Total 100.0

[Example 9]
In accordance with Formulation Example 7, a mixture of known humectants such as 1,3-butylene glycol and polyethylene glycol 1500 in purified water as an aqueous phase is prepared. 5% was blended. As the oil phase part, a solid oil component such as stearic acid, stearyl alcohol and glyceryl monostearate, a liquid oil component such as squalane and octyldodecanol, and oily components such as preservatives and surfactants were prepared. When the water phase is gradually heated to about 80 ° C., the oil phase heated to almost the same temperature is added little by little and emulsified to obtain a cream. To this was gradually added purified water in which potassium hydroxide was dissolved, and the mixture was saponified to obtain the face-washing cream of the present invention.

Formulation Example 7 (face wash cream)
Stearic acid 2.0
Stearyl alcohol 6.0
Hydrogenated lanolin 4.0
Squalane 9.0
Octyldodecanol 10.0
1,3-butylene glycol 6.0
Polyethylene glycol 1500 4.0
Polyoxyethylene (25) cetyl ether 3.0
Glycerol monostearate 2.0
Potassium hydroxide 0.5
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 52.8
Total 100.0

[Example 10]
In accordance with Formulation Example 8, a mixture of purified water and a moisturizing agent such as propylene glycol and O- [2-hydroxy-3-trimethylammoniopropyl] hydroxyethylcellulose as purified water is prepared as an aqueous phase part. 0.5% of moisturizing plant extract was blended. As the oil phase part, a blend of oily components such as polyoxyethylene (2) sodium lauryl ether sulfate, sodium lauryl sulfate, coconut oil fatty acid amidopropyl betaine, highly polymerized methylpolysiloxane, ethylene glycol distearate was prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and stirred to obtain the hair shampoo of the present invention.

Formulation Example 8 (hair shampoo)
Polyoxyethylene (2) sodium lauryl ether sulfate 9.0
Sodium lauryl sulfate 4.0
Palm oil fatty acid amidopropyl betaine 3.0
Highly polymerized methylpolysiloxane 2.0
Methyl polysiloxane 1.0
Palm oil fatty acid monoethanolamide 1.0
Propylene glycol 2.0
O- [2-hydroxy-3-trimethylammoniopropyl] hydroxyethylcellulose chloride 0.5
Ethylene glycol distearate 2.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 74.8
Total 100.0

[Example 11]
According to the formulation example 9, what mixed known moisturizers, such as glycerol, with purified water as an aqueous phase part was prepared, and 0.5% of the moisturizing plant extract of this invention was mix | blended with this. As oil phase part, solid oil such as stearyltrimethylammonium chloride, stearyl alcohol and cetyl alcohol, liquid oil such as highly polymerized methylpolysiloxane, methylpolysiloxane and liquid paraffin, and oily ingredients such as preservatives are prepared. did. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and emulsified to obtain the hair rinse of the present invention.

Formulation Example 9 (hair rinse)
Stearyltrimethylammonium chloride 2.0
Stearyl alcohol 1.0
Cetyl alcohol 2.0
Highly polymerized methylpolysiloxane 2.0
Methyl polysiloxane 1.0
Liquid paraffin 1.0
Glycerin 6.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 84.3
Total 100.0

[Example 12]
According to the formulation example 10, what mixed known moisturizers, such as propylene glycol and glycerin, with the purified water as an aqueous phase part was prepared, and 0.5% of the moisturizing plant extract of this invention was mix | blended with this. As the oil phase part, a blend of oily components such as polyoxyethylene (2) sodium lauryl ether sulfate, triethanolamine lauryl sulfate, coconut oil fatty acid amidopropyl betaine, and ethylene glycol distearate was prepared. When the water phase part was gradually heated and reached about 80 ° C., the oil phase part heated to substantially the same temperature was added little by little and stirred to obtain the body soap of the present invention.

Formulation Example 10 (Body soap)
Polyoxyethylene (2) sodium lauryl ether sulfate 15.0
Lauryl sulfate triethanolamine 5.0
Palm oil fatty acid amidopropyl betaine 5.0
Ethylene glycol distearate 2.0
Glycerol monopalmitate 1.0
Adsorption refined lanolin 2.0
Glycerin 2.0
Propylene glycol 3.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.5
Purified water 64.3
Total 100.0

[Example 13]
According to the formulation example 11, what mixed titanium oxide, antiseptic | preservative, and the fragrance | flavor to the base for soap was prepared, and 1.0% of the moisturizing plant extract of this invention was mix | blended with this. This was die-cut and finished to obtain the solid soap of the present invention.

Formulation Example 11 (Soap)
Soap base 94.5
Titanium oxide 3.0
Preservative 0.5
Fragrance 1.0
Moisturizing plant extract of the present invention 1.0
Total 100.0

[Example 14]
According to Formulation Example 12, a base agent for a bath prepared by adding a fragrance and the like to sodium sulfate and sodium hydrogen carbonate is prepared, and 2.0% of the moisturizing plant extract of the present invention is blended. a.

Formulation Example 12 (Bath Agent a)
Sodium sulfate 48.0
Sodium bicarbonate 48.0
Fragrance 2.0
Moisturizing plant extract of the present invention 2.0
Total 100.0

[Example 15]
According to Formulation Example 13, an oily component such as liquid paraffin, jojoba oil, or preservative was blended with a surfactant and dissolved at about 60 ° C. A fragrance | flavor, purified water, etc. were added to this, 2.0% of the moisturizing plant extract of this invention was mix | blended, and it was set as the bath preparation b of this invention.

Formulation Example 13 (Bath Agent b)
Polyoxyethylene (5) oleyl ether 10.0
Liquid paraffin 80.0
Jojoba oil 5.0
Preservative 0.2
Fragrance 1.8
Moisturizing plant extract of the present invention 2.0
Purified water 1.0
Total 100.0

[Example 16]
According to Formulation Example 14, a cosmetic base prepared by mixing hair nutrients such as assembly extract, tocopherol acetate, pantothenyl ethyl ether, etc. with ethyl alcohol in which preservatives, fragrances and the like are dissolved at room temperature is purified. 0.3% of water and the moisturizing plant extract of the present invention were blended to obtain a hair restorer of the present invention.

Formulation Example 14 (Hair restorer)
Ethyl alcohol 60.0
Assembly extract 5.0
Tocopherol acetate 0.2
Pantothenyl ethyl ether 0.2
Propylene glycol 5.0
Preservative 0.1
Fragrance 0.2
Moisturizing plant extract of the present invention 0.3
Purified water 29.0
Total 100.0

[Example 17]
According to the formulation example 15, what mixed ascorbic acid, antiseptic | preservative, etc. in the purified water as an aqueous phase part was prepared, and 0.3% of the moisturizing plant extract of this invention was mix | blended with this. As the oil phase portion, a solid oil component such as polyoxyethylene (10) oleyl ether, a liquid oil component such as oleic acid and isopropyl alcohol, and an oily component such as a preservative were prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and emulsified to obtain the cream of the present invention.

Formulation Example 15 (Hair dye 1st agent)
Oxidative dye 4.0
Polyoxyethylene (10) oleyl ether 15.0
Oleic acid 20.0
Isopropyl alcohol 10.0
Ammonia water (28%) 10.0
Ascorbic acid 0.5
Preservative 0.1
Fragrance 0.3
Moisturizing plant extract of the present invention 0.3
Purified water 39.8
Total 100.0

[Example 18]
According to Formulation Example 16, 0.3% of the moisturizing plant extract of the present invention is blended with a base obtained by mixing hydrogen peroxide water and a fragrance with purified water at room temperature, and the second hair dye of the present invention. It was.

Formulation Example 16 (Hair dye 2nd agent)
Hydrogen peroxide solution (30%) 20.0
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 79.6
Total 100.0

[Example 19]
In accordance with Formulation Example 17, prepared is a mixture of purified water with a known humectant such as glycerin and a thickener such as sodium carboxymethylcellulose, carrageenan, etc. as the water phase part, and dicalcium phosphate dihydrate, anhydrous silicic acid. Then, sodium lauryl sulfate was mixed and 0.3% of the moisturizing plant extract of the present invention was blended. Sodium saccharin, a fragrance, and a preservative were added to a part of the purified water, and this was mixed and deaerated into the aqueous phase part to obtain a toothpaste of the present invention.

Formulation Example 17 (Toothpaste)
Dicalcium phosphate dihydrate 45.0
Silica anhydride 2.0
Glycerin 15.0
Sodium carboxymethylcellulose 1.0
Carrageenan 0.3
Sodium lauryl sulfate 1.5
Saccharin sodium 0.1
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 34.6
Total 100.0

[Example 20]
According to Formulation Example 18, glycerin and polyoxyethylene hydrogenated castor oil were added and dissolved in purified water. To this, 1-menthol and a fragrance dissolved in ethyl alcohol were added and mixed and dissolved. Further, sodium saccharin and chlorhexidine gluconate were added and dissolved, and 0.3% of the moisturizing plant extract of the present invention was blended to make the mouthwash of the present invention.

Formulation Example 18 (Mouthwash)
Ethyl alcohol 40.0
Glycerin 10.0
Polyoxyethylene hydrogenated castor oil 1.0
1-menthol 0.5
Saccharin sodium 0.05
Chlorhexidine gluconate 0.02
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 48.03
Total 100.0

[Example 21]
According to the formulation example 19, what mixed polypropylene glycol, ethyl alcohol, and antiseptic | preservative in purified water as an aqueous phase part was prepared, and 0.3% of the moisturizing plant extract of this invention was mix | blended with this. As an oil phase part, what mix | blended polyoxyethylene (2) sodium dodecyl sulfate, lauryl glucoside, and the fragrance | flavor oil component was prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion was added little by little and stirred to obtain the dishwashing detergent of the present invention.

Formulation Example 19 (Dishwashing detergent)
Polyoxyethylene (2)
Sodium dodecyl sulfate 15.0
Lauryl glucoside 12.5
Ethyl alcohol 5.0
Polypropylene glycol 3.0
Preservative 0.1
Fragrance 0.1
Moisturizing plant extract of the present invention 0.3
Purified water 64.0
Total 100.0

Use test of various preparations for external use (1) Implementation procedure The lotion, cream, hair shampoo, hair rinse, bath preparation B, hair restorer, dishwashing detergent produced in each example are used as test products (A), and men and women panelists ( A use test was conducted by all 15 people). As a comparative product (B), a preparation excluding the moisturizing plant extract or extract of the present invention is prepared during the formulation of each external preparation composition. For one month, the comparison product (B) was used under the following conditions, and an answer by a questionnaire was requested.

(2) Usage conditions The lotion of Example 3: Immediately after washing in the morning and immediately after bathing at night, 3 ml each (once / day) was applied to the face.
Cream of Example 5: Apply 1 g (once / day) to face before going to bed.
Hair shampoo of Example 10: 10 ml, (once / day) used during shampooing.
Hair rinse of Example 11: Immediately after shampooing, use 10 ml (once / day).
Bath agent b of Example 15: 30 g of bath water was poured into about 200 L of bath water (once / day).
Hair restorer of Example 16: After washing the hair, 3 ml, (once / day) was applied to the scalp.
Tableware detergent of Example 21: As needed.

(3) Questionnaire results: Tables 2 and 3 show the results of questionnaire responses.

  The moisturizing plant extract of the present invention continues to have a moisturizing effect for a long time, and the cosmetic and bath preparation containing the extract prevent dryness, rough skin, cracks, red snapper, dandruff, kayumi and the like on the skin. It is effective for reduction or improvement, and for hair, such as dryness, dryness, split ends, cut hair, and gloss. In addition, even in household detergents that have been concerned about skin troubles such as rough skin, cracks, and redheads, the moisturizing plant extract of the present invention eases such troubles so that it does not easily occur, and is a detergent that touches the skin. A composition can be provided.

It is a graph which shows the moisture retention of the moisturizing plant extract of this invention, and its constituent raw material crude drug extract.

Claims (9)

A botanical skin or hair moisturizer comprising an extract of a mixture of poppy, peony, tonin, bukkake, button pi, licorice and ginger . 0.3 to 8 parts by weight (parts by weight) (hereinafter the same), 0.3 to 8 parts of peony, 0.3 to 8 parts of peony, 0.3 to 8 parts of horse chestnut, 0.3 to 8 parts of button pie, 0 of licorice A botanical skin or hair moisturizer comprising an extract of a mixture of 0.1 to 6 parts and 0.1 to 6 parts of pepper. 2-5 parts by weight (parts by weight) (the same shall apply hereinafter), 2-5 parts of peony, 2-5 parts of peony, 2-5 parts of horse chestnut, 2-5 parts of button pi, 0.3-4 parts of licorice and 0.0. A botanical skin or hair moisturizer comprising 3-4 parts of an extract of the mixture. The plant skin or hair moisturizer according to any one of claims 1 to 3, which is an extract of water, alcohols, or a mixture thereof. The vegetable skin or hair moisturizer according to any one of claims 1 to 4, wherein the amount of the extraction solvent is 10 to 100 times the amount of the extract. An external preparation composition comprising the vegetable skin or hair moisturizer according to any one of claims 1 to 5. A cosmetic composition comprising the botanical skin or hair moisturizer according to any one of claims 1 to 5. A bath preparation composition comprising the botanical skin or hair moisturizer according to any one of claims 1 to 5. A detergent composition comprising the vegetable skin or hair moisturizer according to any one of claims 1 to 5.

Images