JP2008094739A - Skin texture ameliorant and external preparation, cosmetic, bath medicine and detergent containing the skin texture ameliorant - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To obtain a skin texture ameliorant that is safe to the skin, has an excellent sense of use and restores the skin texture of human skin having no skin texture and a beautiful skin cosmetic, a bath medicine and a detergent composition containing the skin texture ameliorant. <P>SOLUTION: The skin texture ameliorant comprises an extract of a mixture of Angelica acutiloba Kitagawa, Paeonia lactiflora Pallas, Cnidium officinale Makino, Rehmannia glutinosa Liboschitz var. purpurea Makino, Coptis japonica Makino, Phellodendron amurense Ruprecht, Scutellaria baicalensis Georgi and Gardenia jasminoides Ellis. The texture ameliorating external preparation, the cosmetic, the bath medicine and the detergent composition contain each the extract. A medicine obtained by decocting the crude medicines in a fixed ratio is called Unseiin in traditional Chinese medicine and is said to have an effect on irregular menstruation, dysmenorrhea, stale blood, menopausal disorders and neurosis when a person having bad skin texture and feeling dizzy internally takes its decocted solution. The extract of the mixture of these crude medicines has a synergistic texture amelioration effect in comparison with an extract of single crude medicine and takes an amelioration effect on chapped skin by external use. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a skin texture improving agent, which improves rough skin, restores texture to human skin that has no texture, and provides a skin texture improving agent and the texture improving agent. The present invention relates to a cosmetic, a bath preparation and a detergent composition containing

  The desire for beautiful skin is a common desire for women, and various skin care cosmetics have been proposed. As a skin external preparation excellent in skin beautifying effect and moisturizing effect, for example, a skin external preparation containing an aqueous layer part obtained by filtering pressed fruit juice of Rahan fruit with a nano filter is skin texture, rough skin, skin peeling, wrinkles, etc. (Patent document 1), the morning use characterized by combining cosmetics containing only antioxidants, or antioxidants and components that do not interfere with the effects of the antioxidants, with the turnover cycle of cells Skin care cosmetics (Patent Document 2) and the like have been proposed. However, the proposal of the material from the viewpoint of improving the texture of the skin itself is insufficient.

  On the other hand, regarding the use of Kampo materials for topical skin use, moisturizing plant extracts composed of extracts of Toki, Diou, Peonies, Senkyu, Auren, Ogon, Sanshishi and Aoba have a gentle and excellent moisturizing effect on the skin. Although it has been proposed (Patent Document 3), the skin beautifying effect has not been sufficiently studied.

JP 2005-89427 A JP 2005-170805 A JP 2004-10503 A

  Conventional skin beautifying materials have been mainly unsatisfactory in terms of the prevention of rough skin and the restoration of skin texture as well as safety and usability.

  The present invention solves such a problem, and is a skin texture improving agent that restores texture to human skin that is safe to the skin, excellent in feeling of use, and has no skin texture, and the extract. Provided are skin-beautifying cosmetics, bath preparations and detergent compositions.

  In order to solve the above-mentioned problems, the present inventors searched for various plant extracts and mixtures thereof, and as a result, the extract having the same composition as the Chinese herbal unseiin formula was synergistically excellent. The inventors have found that the present invention is effective and completed the present invention. That is, the present invention is a skin texture-improving agent comprising an extract of a mixture of Toki, Peonies, Senkyu, Giou, Auren, Oubak, Ogon and Sanshishi. Specifically, 0.4 to 10 parts by mass of Toki (parts by mass, hereinafter The same), peonies 0.3-7.5 parts, senkyu 0.3-7.5 parts, diau 0.4-10 parts, aurene 0.2-3.8 parts, apricot 0.2-3.8 parts , A skin texture-improving agent comprising an extract of a mixture of 0.3 to 7.5 parts of ogon and 0.2 to 5 parts of sushi, and more specifically 1.6 to 8 parts of toki, 1.2 to peony 6 parts, Senkyuu 1.2-6 parts, Giou 1.6-8 parts, Ouren 0.6-3 parts, Owaku 0.6-3 parts, Ogon 1.2-6 parts and Sanshishi 0.8-4 parts Is a skin texture improving agent comprising an extract of Or, 2.8-6 parts of Toki, 2.1-4.5 parts of Peonies, 2.1-4.5 parts of Senkyu, 2.8-6 parts of Geow, 1.1-2.3 parts of Ouren, A skin texture improving agent comprising an extract of a mixture of 1.1 to 2.3 parts, 2.1 to 4.5 parts of Ogon and 1.4 to 3 parts of Sanshishi, and water or alcohols or their The skin texture improving agent characterized by being an extract of a mixture, and the amount of the extraction solvent is 10 to 100 times that of the extract. And an external preparation composition containing the skin texture improving agent, and a cosmetic composition characterized by containing the skin texture improving agent, and A bath agent composition characterized by containing the skin texture improving agent, And a detergent composition characterized by containing a texture improving agent of the skin.

  The plants used in the present invention are shown below, and any of them can use leaves, stems, roots, flowers, seeds or whole plants. In addition, herbal medicines originating from the following plants may be used.

(1) Touki: Angelica acutiloba Kitagawa or A. acutiloba Kitagawa var. Sugiyamae Hikino root, usually boiled (Apiaceae)
(2) Peonies: Paeonia lactiflora Pallas roots (buttons)
(3) Senkyu: Cnidium officinale Makino rhizome, usually boiled (Apiaceae)
(4) Giant: Rehmannia glutinosa Liboschitz var. Purpurea Makino or R. glutinosa Liboschitz as it is (dry yellow) or steamed (ripe yellow) (Lepidoptera)
(5) Ouren: Coptis japonica Makino, C. chinensis Franchet, C. Deltoides CYCheng et Hsiao or C. teeta Wallich
(6) Buckwheat: Bark excluding pericarp of Phellodendron amurense Ruprecht or Phellodendron chinense Schneider (Rutaceae)
(7) Ogon: Root without pericytes of Scutellaria baicalensis Georgi (Lamiaceae)
(8) Sanshishi: Fruits of Gardenia jasminoides Ellis (Rubiaceae), but the type of each herbal medicine is not limited to this, and varieties, homologous species, and other related species can also be used.

  Hot drink is a combination of 8 kinds of Toki, Peonies, Senkyu, Giou, Auren, Oubak, Ogon, Sanshishi, and decocted. It is said to be effective for irregular menstruation, dysmenorrhea, bloody thrombosis, menopause, and neurosis.

  It is said that warm drink is effective for internal treatment against eczema, dermatitis, and blood outbreak, although the affected area is dry and reddish, has a burning sensation, and itchy and powdery spills. Physical and pharmaceutical sciences (published by Shuji Itokawa, Taichi Omoto, Masahiro Nagai, Riki Furuya, published by Asakura Shoten, April 10, 1987) and practice of Kampo medicine (Takashi Otsuka, Michiaki Yaha, Fujitaro Shimizu, published by Nanzan-do) February 15, 1958 version)].

  The active ingredient is extracted from these plants using a suitable solvent. Examples of the solvent include water, alcohols (for example, lower alcohols such as methanol, absolute ethanol, and ethanol, or polyhydric alcohols such as 1,3-butylene glycol, propylene glycol, and dipropylene glycol). Any mixture can be used. Moreover, after extraction, the extract is diluted or concentrated and dried as necessary.

  The production method is not particularly limited, and may be in the range of the boiling point of the solvent at normal temperature or normal pressure, and a microwave extraction method or a supercritical extraction method may be used. After extraction, filtration or ion exchange resin may be used for adsorption, decolorization, and purification to form a solution, paste, gel, or powder. In many cases, it can be used as it is, but if necessary, further purification treatment such as deodorization and decolorization may be added as long as the effect is not affected. An activated carbon column or the like may be used, and usual means generally applied depending on the extracted substance may be arbitrarily selected.

  As for the crude drug used in the present invention, an extract having a high effect is obtained from a combination of eight kinds extracted, and an extract having a higher effect is preferably obtained from a combination of eight kinds extracted at a specific ratio. Therefore, it is more effective than individual extraction from each, extraction by arbitrarily combining up to 7 kinds of plants, and mixing and using each extract or extract. In addition, since the texture improvement effect improves more by extracting and combining eight types of plants, and the result which the improvement effect with respect to rough skin becomes further favorable, what extracted and combined eight types of plants, Preferably Is considered to be sufficiently meaningful to use 8 types extracted at a specific ratio.

  The compounding amount of each herbal medicine used in the present invention is a collection of experienced Chinese medicine prescriptions (published by Nippon Shokudo Co., Ltd., 9th edition, 1993), and a guide to general Chinese medicine prescriptions (edited by the National Pharmacopoeia Special Committee, Ministry of Health Supervised by the Ministry of Public Affairs, published by Yakuho Times Publishing Co., Ltd., April 30, 1992, 4th edition, 12 printing), but the preferred blending amount is 0.4-10 parts of Toki (mass part, the same shall apply hereinafter), Peonies 0.3-7.5 parts, Senkyu 0.3-7.5 parts, Diou 0.4-10 parts, Auren 0.2-3.8 parts, Oubak 0.2-3.8 parts, Ougon 0 .3 to 7.5 parts and sanshishi 0.2 to 5 parts, particularly preferably 1.6 to 8 parts of Toki, 1.2 to 6 parts of peony, 1.2 to 6 parts of Senkyu, 1.6 to 8 parts, 0.6 to 3 parts of auren, 0.6 to 3 parts of buckwheat, 1.2 to 6 parts of ougon, and 0. To 4 parts, most preferably from 2.8 to 6 parts of Toki, 2.1 to 4.5 parts of peony, 2.1 to 4.5 parts of Senkyu, 2.8 to 6 parts of Diou, 1.1 to 2.3 parts, 1.1 to 2.3 parts of buckwheat, 2.1 to 4.5 parts of ugone, and 1.4 to 3 parts of Sangishi.

  The external preparation composition, cosmetic composition, bath preparation composition and detergent composition according to the present invention are usually used in, for example, the cosmetics described below in addition to the essential skin texture improving agent of the present invention. It can be produced by using a base, an additive and the like.

(1) Various fats and oils: avocado oil, almond oil, fennel oil, sesame oil, olive oil, orange oil, orange rafa oil, sesame oil, cocoa butter, chamomile oil, carrot oil, cucumber oil, beef tallow fatty acid, cucumber oil, safflower Oil, shea fat, liquid shea fat, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil, palm oil, palm kernel oil, owl, Coconut oil, beef tallow, lard, or hydrogenated products of these oils (hardened oil, etc.).

(2) Waxes: beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax, squalene, squalane, pristane and the like.

(3) Mineral oil: liquid paraffin, petrolatum, paraffin, ozokelide, ceresin, microcrystalline wax and the like.

(4) Fatty acids: natural fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tall oil, lanolin fatty acid, isononanoic acid, caproic acid, 2 -Synthetic fatty acids such as ethylbutanoic acid, isopentanoic acid, 2-methylpentanoic acid, 2-ethylhexanoic acid and isopentanoic acid.

(5) Alcohols: natural alcohols such as ethanol, isopyropanol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, phytosterol, and synthetic alcohols such as 2-hexyldecanol, isostearyl alcohol, and 2-octyldodecanol.

(6) Polyhydric alcohols: ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, 1,3-butylene glycol, 1,2-pentanediol, glycerin, diglycerin, pentaerythritol, sorbitol, mannitol and the like.

(7) Esters: isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate , Diethyl phthalate, dibutyl phthalate, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate, and the like.

(8) Metal soaps: aluminum stearate, magnesium stearate, zinc stearate, calcium stearate, zinc palmitate, magnesium myristate, zinc laurate, zinc undecylenate and the like.

(9) Gum, saccharides or water-soluble polymer compounds: gum arabic, benzoin gum, dammar gum, guaiac oil, Irish moss, karaya gum, tragacanth gum, carob gum, quinseed, agar, casein, lactose, fructose, sucrose or esters thereof , Trehalose or derivatives thereof, dextrin, gelatin, pectin, starch, carrageenan, carboxymethylchitin or chitosan, hydroxyalkyl (C2 to C4) chitin or chitosan to which alkylene (C2 to C4) oxide such as ethylene oxide is added, small molecule Chitin or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid or salt thereof, hyaluronic acid or salt thereof, chondroitin sulfate or salt thereof, heparin, ethylcellulose, methyl Cellulose, carboxymethyl cellulose, carboxyethyl cellulose, carboxyethyl cellulose sodium, hydroxyethyl cellulose, hydroxypropyl cellulose, nitrocellulose, crystalline cellulose, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylate, polyethylene oxide, polypropylene oxide, etc. Polyalkylene oxide or a crosslinked polymer thereof, carboxyvinyl polymer, polyethyleneimine and the like.

(10) Surfactant: Anionic surfactant (alkyl carboxylate, alkyl sulfonate, alkyl sulfate ester salt, alkyl phosphate ester salt), cationic surfactant (alkyl amine salt, alkyl quaternary ammonium salt), Amphoteric surfactant [carboxylic acid type amphoteric surfactant (amino type, betaine type), sulfate ester type amphoteric surfactant, sulfonic acid type amphoteric surfactant, phosphate ester type amphoteric surfactant], nonionic surfactant Agents (ether type nonionic surfactants, ether ester type nonionic surfactants, ester type nonionic surfactants, block polymer type nonionic surfactants, nitrogen-containing type nonionic surfactants), other surfactants Agents (natural surfactants, derivatives of protein hydrolysates, polymer surfactants, surfactants containing titanium and silicon, Tsu carbon-based surface active agent), such as.

(11) Various vitamins Vitamin A group: retinol, retinal (vitamin A1), dehydroretinal (vitamin A2), carotene, lycopene (provitamin A), vitamin B group: thiamine hydrochloride, thiamine sulfate (vitamin B1), Riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), folic acid, nicotinic acids, pantothenic acids, biotins, choline, inositols, vitamin C group: vitamin C acid or derivatives thereof, vitamin D group: Ergocalciferol (vitamin D2), cholecalciferol (vitamin D3), dihydrotaxosterol, vitamin E group: vitamin E or derivatives thereof, ubiquinones, vitamin K group: phytonadione (vitamin K1), menaquinone (vitamin K2 , Menadione (vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, .gamma.-oryzanol, orotic acid, vitamin P such (rutin, eriocitrin, hesperidin), and vitamin U.

(12) Various amino acids: valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxy Amino acid derivatives such as lysine, arginine, ornithine, histidine, and their sulfates, phosphates, nitrates, citrates, or pyrrolidone carboxylic acids.

(13) Various additives derived from plant or animal materials: These are processed in a conventional manner according to the product type and form to be added (for example, pulverization, milling, washing, hydrolysis, fermentation, Purify, squeeze, extract, fractionate, filter, dry, pulverize, granulate, dissolve, sterilize, adjust pH, deodorize, decolorize, etc.) And serve.

  The solvent used for extraction may be selected in consideration of the intended purpose and type of the product to be provided, or the processing performed later. Usually, water, a water-soluble organic solvent (for example, ethanol, propylene glycol) , 1,3-butylene glycol, and the like) are preferably used. However, when it is not preferable to contain an organic solvent depending on the application, it is sufficient to use only water or ethanol that can be easily removed after extraction, and it may be used alone or in any mixture with water. The thing extracted and extracted may be sufficient.

  In addition, when using additives derived from plant or animal raw materials for systemic or topical external preparations, cosmetics, including protection of skin and hair, antioxidant, improvement of touch / feel, imparting flexibility, Relaxation of stimulation, stress reduction by fragrance, cell activation (prevention of cell aging), suppression of inflammation, improvement of skin / hair quality, prevention of rough skin and its improvement, hair growth, hair growth, prevention of hair loss, imparting luster, cleaning effect In addition to cosmetic effects such as fatigue relief, blood flow promotion, and warm bath effects, effects such as flavoring, deodorizing, thickening, preserving, and buffering can also be expected.

  In addition to this, various cosmetic and pharmaceutical effects of each of the known raw materials are expected, and by combining these, the intended effect can be promoted or multifunctional. It is also possible to make the product expected to be effective.

Specific plants used as raw materials include, for example, almond, eye, blue quail, aoki, Aokiri or Kenashiaogiri, Aotsuki-rafuji, acacia, red pepper, red currant, red grape, redwood (logwood), red-crowned, red, red or yellow Aki larch, Akinire, Aguahe (Omanten palm), Akebi, Asa, Maruba asagao or Asagao, Hydrangea, Ashitaba, Azuki, Acerola, Asenyaku, Achilla (Anchorana), Anise, Abemaki, Ama, Amacha, Amachaa, Amacha (Amaranthus, Hypochondriacus), Amigasayuri or Baba (Amaranthus, Hypochondriacus) Mo, Arcana (Arkanna), Argarovo (Cabbage), Altea, Arnica, Alpinia or Katsumadai (Suzukuku), Aloe, Aloe Vera, Angelica, Apricot or Honzu, Ansokkou, Igakouzorina, Ikarisou or Yatsuma Taikoshi (Isoyokakuta) , Yew, Strawberry, Fig, Ichihatsu, Ichibi, Ichiyakusou, Ginkgo biloba, Itohimegi, Locust Bean, Inazuna (Tailexi), Inubibi (Honagainubiyu), Rice, Inondo, Ibukikosou, Nettle, Iranian Iran, Iwa tobacco, Iwa tobacco, Iwa tobacco, Iwa cigarette , Wheat (Chibusanoki), Spiraea, Warbler, Japanese duckweed, Duckweed, Usbasaicin or Keirinsaishin or Oshusaishin Usbenia mushroom, Usbenitachaoi, Nepenthes, Udo or Shishido, Unyadegato (Unkalia, Cats Claw), Uba tea, Ume, Vulgara, Uwaurushi (Kusakokemo), Unsumikan, Estragon, Ezocogi, Echinashibisugakue Or Cassia Tora, El Campre, Elderberry, Elemi, Elingi or Pre-Lotus Elinge, Enju, Ogi or Kibanaougi, Okarasuuri (Karokon), Oguruma, Ootsuki Rafuji, Obaco, Toucanami, Obanaokera or Okera, Obera , Steller's chabushi, sea hawthorn or hawthorn, seisei (narukoyuri, kagulmabanarukoyuri), yukisanoyuki or sasano Yuki, Barley, Oshigusa, Oka, Okazeri, Oguruma, Okra, Panax Ginseng or Tochibaninjin, Hypericum or Ginseng or Hypericum Hypericum, Odrichospodium, Onomomi, Onigorori, Nigorio , Halibut, ominae, yuuko, dutch mustard (watercress), dutch jellies, dutch honey bees, olives, oregano, orange, silkworm, cacao, oysters, scallops, oysters or cantris, cassia, casino oysters, oaks, cascarilla, cascarilla Sagrada, gypsophila, cynomolgus, kaniwa, valerian, birch or fern birch, pumpkin, kapok, Japanese cabbage , Cattail, chamomile or roman chamomile, camilla deer, camouflage (camo duck), calax salmon man, crow cucumber or cinnamon cucumber, crow birch, oats, guarana, carahoo, karaya, karin, garcinia, kawamidori, kawadashi, kawara kawade Carrot, Kawaramugi, Kansui, Kanzo, Kantara Asa, Candelilla, Ganto, Canna, Raspberry (Ezo Strawberry, Dutch Strawberry, Shrimp Strawberry, Maple Strawberry, Maple Strawberry, European Raspberry), Kiwi, Kikarasuri, Kyoji, Chrysanthemum, Chrysanthemum Bark, pheasant, kizuta, kidachi aloe, kidachiha mint, kina, linden (shinkona, red linden), quinoa Quinoa), kihada, gymnema sylvestre, cabbage, cabbage, cucumber, gyory, kiraja saponaria, kiraya, giraffe, kumquat, betel, guinea pig, guava, guayule, quellus infectria, cucumber, kuco Gooseberry, Ginseng, Gardenia, Kunugi, Kupuas, Kumazasa, Kumamatsura, Clara, Cranberry, Chestnut, Curkurigo Latifolia, Grapefruit, Chrysanthemum, Scarlet Mochi, Kurobana Hioki Koshi, Gunby Tuna (Sekimei, Sekimeishi), Keii Kenashi Sartorii rose, Gentiana, Gennoshouko, Kemponashi (Kigushi), Kokisekoku, Kishimizukan (Koji, Tachibana) , Tiger beetle, buckle mandarin, sagamikoji, ponkan, santara, koshinbara, kouseihakka, kozo, kocha, kohone, kohon, kouliang, koryokukyo, cilantro, kouren, koganebana, kobemo, coconut palm, coconut palm, coffee , Kobushi or magnolia, burdock, kobotanru, sesame, sesame seedling, trash, honeysuckle or binankazura or pine bush, wheat, rice or rice bran, rice oil, cola acuminata, cola vera, coloha, colombo, kondurango, kombu, konnyaku, comfrey , Sisal (Sisal Asa), Saxima button eel or Syna button eel or Cinnamon, Sakura (Oshima cherry, Yamazakura, Oyamazakura, Edhigashi, (Cherry tree, cherry tree, cherry tree, cherry tree, cherry tree, butterfly cherry, butterfly, cherry tree, cherry tree, cherry tree, cherry tree, pomegranate, sweet cherry, sweet cherry, sweet potato, sweet cherry, saffron, pomegranate) , Salvia (Sage), Sagaki Kyo, Sawagurumi, Sangre de Grado (Croton), Salamander, Sancyn carrot, Sanshuyu, Salamander, Sandscon, Shea (Kalite), Cyanoki, Shiitake, Zion, Diquitaris, Sikunshi, Perilla or Aojiso Or Chile-swordfish or Catamenziso, Rosewood, Shinanoki, Shinohonoki, Sinarenyo, Shimeji (Hinshimeji, Shakashimeji, Hatake-shimeji, Hatake-shimeji, Oshiroi-shimeji (Bunashimeji, Honjimeshi, Shirotamogitake), Shimotsuke, Potato, Shajin, Jasmine (Matsurika), Janohige, Shukukonkamiso, Shukushamitsu, Juzudama, Shuro, Zouzanjisai, Shobu, Shozuk, Shirakashi, Shirosuisiroi ), Shirobanatsuta, Shirominanten, Cinchona sylbra, Ginkgo biloba, Cinnamon, Watermelon, Honeysuckle, Sorrel, Swimberry, Stevia, Strawberry, Psycho, Horsetail, Prunus, Sumomo Hawthorn, dandelion, horse chestnut (marronnier), pear, sunflower, elderberry (elder) , Alaska spruce (Juniper), Achillea millefolium (milfoil), Rose rose, Papilion butterfly, Mistletoe serrata, Sorax or squirrel, Horseradish, Sekisho, Sekkoku, Cedron, Shirohasega Senshinren, Sendan, Senburi, Senna, Sennin, Soka, Buckwheat, Somer potato, Daio, Daikon, Soybean, Daidai, Takasaburo, Takatodai, Takarabi, Dark Sweet Cherry, Hollyhock, Tachikakuso (thyme), Tachidokoro (Hikai), Tachidoya , Onion, tanshiba, taranki, tarwi, tanjin, dandelion or white dandelion or mouko dandelion, danmar, cherry, chigaya Chixetsu carrot, chicory, champiedra, ginseng, ginseng, ginseng, choreimaitake, chorogi, camellia, mushroom (mushroom), camellia, camellia, clover, cinnamon, vine , Camellia, deco, euglena, duberry, proboscis, tencha, daidai yak, capsicum, capsicum, capsicum, capsicum (marigold), tounabena, corn or corn, capsicum, sprig, ginseng, crested swordfish Toshishi or Mamedaoshi or Nekazura, Eucommia, Tonerico, Tomato, Tragacanth, Triacanthus, Tormentilla, Doronoki, Loroaoy, Neisseria berry, Chinese yam or yam, Nagii kada (butcher bloom), Naginata kouju, Nazuna, Rapeseed, Solid bean or Vertical bean, Natsume, Jujube, Naniwaibara, Navena, Nameko, Narco lily, Nambai, Nambai Kay or Nikkei or Ceylon Nikkei or Yab Nikkei or Keishi, leek, elderberry, garlic, nurde, leek, leeks or neb or snake or nemlinoki or sagebana, black thistle, horned rose, yarrow, peach, palm, pineapple, palm, pineapple, , Fulin Bussouge, Roselle), Hailindo, Hakamaurabosi, Huxen, Hakulberry, Jacobe, Hazel, Hasilidokoroko, Basil, Lotus, Pas Seri (Netherlands jellies), Hadakamugi, Batata, Hachiku or Madatake, Patchouli, Hakka, Barley (Yokuinin), Hanasuge, Banana, Hanakaha, Hanabishi (Sitoshiri, Shitsutsuri), Vanilla Bins, Jachagusa, Pahalobobo, Hub, Paprika, Hamagomi , Hamasuge, Habibishi, Hamanasu (Maikai flower), Hamaboufu, Hammeris, Rose, Agaric (Agaric, White-faced Agaric, Ukimorinokasa), Haran, Pariurus (Prunus japonicus), Parietalia, Balsamina (Turureshi, Nigaharin), Haruni Handikai, breadfruit, halibut, lizard carrot, puer tea, pecan nuts, ganbanana, bean, pistachio, beet, human camellia, kinglet, fern, Tree, Hiba, Castor, Sunflower, Pepper, Himeuzu, Himamatsu, Himematsutake (Kawariharatake, Hiromatsutake), Pimenta, Sandalwood, Sandalwood, Panther, Yellow-tailed oil, Yellow-backed beak, Biwa, Binrow, Pepper-tip Grape, Beech, Fuyumushinatsutake, Brazilian licorice, Brazilian carrot, Black currant, Blackberry, Plum, Fruceraria, Blueberry (Prunus japonica), Prunes, Blond psyllium, Bundow, Hazelnut, Loofah, Safflower, Henken, Belladonna, Berry, Permianberg, Astragalus or Stingweed, Boysenberry, Butterweed or Duckweed or Nendoroid or Hahagigi Kokia, Binsenga, Butterberry, Bow Cormorant, spinach, physalis, physalis, bokeh, squirrel, spruce, spruce, barnyard, buttonfish, button pie, hops, jojoba, bordeaux, whirlberry, hononiku, honseokoku, mizultennansho, maitake, mao, mika, maca , Makri, Magwa, Magnolia Splengeri, Mashua (Tamanozenhalen, Kyukonkinrenka), Matatabi, Matsukasa, pine, Matsuhodo, Matico (Cordon sillo), Mayoram (Hanahakka), Malvano jardin, Mulberry, quince, Mangosteen, Mangosya ( Andesukamitsuru), Manshugurumi, Mandarin, Mannentake, Pheasant, Mishimashiko, Mizuohobako or Mizuasagao, Mizokushi, Misohagi, Michiyanagi or Are: Willow, Mitsuwashi, Honey Bee, Green Hazel, Mimosa, Miogua, Miracle Fruit, Myrrh, Milobaran, Wheat Waragiku, Mukugegi, Mukunoki, Mukuroji, Munya, Murasaki, Murasakikibu or Omurasakikibu, Murasakiki Maki, Botanus Melissa, Melilot, Melon, Moukomugi, Mosouchiku, Mogi (Pepper), Mokko, Momijidaio, Peach, Moyashi, Morello Cherry, Morohaya, Yakawa Murasakiimo, Yakuchi, Cornflower, Cornflower Shark Himeyabushi or Ooyabayashabushi, Yachiyanagi, Yatsude, Mistletoe, Willow (Kawayanagi, Tachiyanagi, Weeping Willow, Red Willow, Pussy Willow, Dog Lianagi, Kinuyanagi, Koryanagi, Unryu willow, Miyama willow, palm, Yamayanagi, Obayanagi, Tairikinu Yanagi, Fox willow, Dronoki), Yanagitade, Yabugarashi, Yabukoji, Yamukano, Yamano, Yamano, Yamano, Yakino Yuzu, Lily, Wormweed, Artemisia, Ligan, Lime, Rye, Lacanca, Raspberry, Latania (Clamelia), Lackey or Shallot, Lavender, Longan, Agave (Aonorus agave, Fukurin Agave), Ryukcha, Apple, Gentian, Rubus Ganoderma, lettuce (red pepper), red currant, lemon, lemongrass, forsythia or Chinese forsythia, ren So, Rouyashi, Lokon (Yoshi), loganberry, rosemary (Rosmarinus officinalis), rose hip (Novara), wasabi, and the like Burnet.

  In addition, other seawaters such as sea salt, dried seawater, dead sea or Atlantic or Pacific seawater (sodium chloride, magnesium chloride, potassium chloride, etc.), sea mud or mud (fango), such as Sea mud or mud in various regions such as Italy, France, Germany, Eifel and Franceburg (Contained components: silicon dioxide, titanium dioxide, aluminum oxide, iron oxide, manganese oxide, sodium oxide, potassium oxide, magnesium oxide, calcium oxide) Strontium oxide, sodium, potassium, magnesium, calcium, chromium, iron, copper, nickel, zinc, lead, manganese, arsenic, water), saintoku stone and so on.

  As seaweeds, seaweed [Green algae: Chlorella vulgaris, Chlorella pyrenoidosa, Chlorella ellipsoidia, Aonori (Usubaonori, Susiaoonori, Hiraonori), seaweed [Brown algae: Kombu, Macub Hosome Kombu, Mitsuishi Kombu), Wakame, Hirome, Aowakame, Giant Kelp (Macrocystis pirifera, Macrocystis integrofolia, Hijiki, Hibamata), seaweed [Red algae: Hijirimen, Maxa (Tengusa)], Nettle, cypress, prickly pear, caterpillar, yatabegusa, yui-kiri, striped primrose, crested beetle, spruce rhinoceros, crested rhinoceros, giraffe rhinoceros, ginseng giraffe, horned mackerel Mata, carrageen (Yahazutsunomata), Ezotsunomata, Togetsunomata, Hirakotoji, Kotojitsunomata, Suginori, Shikin'nori, Kainori, Ibotsunomata, Yareusubanori, Kagiusubanori, Sujiusubanori, Haiusubanori, Akamomijinori] and the like as a representative.

  In addition, animal-derived materials include poultry extract, bovine, porcine or human placenta extract, porcine or bovine stomach, duodenum or intestinal extract or its degradation product, porcine or bovine spleen extract Or a degradation product thereof, an extract of porcine or bovine brain tissue, a water-soluble collagen, a collagen derivative such as acylated collagen, a collagen hydrolyzate, elastin, an elastin hydrolyzate, a water-soluble elastin derivative, keratin and a degradation product thereof, or Derivatives thereof, silk proteins and degradation products thereof or derivatives thereof, porcine or bovine blood cell protein degradation products (globin peptides), porcine or bovine hemoglobin degradation products (hemin, hematin, heme, protoheme, heme iron, etc.), milk, Casein and its degradation products or their derivatives, skim milk powder and their degradation products or their derivatives, lactoferrin or their degradation products, chicken Component, fish meat decomposition products such as.

(14) Microbial culture metabolite yeast metabolite, yeast extract, natto metabolite, natto extract, rice fermented extract, rice bran fermented extract, euglena extract, lactic acid fermented milk or skim milk or trehalose or derivatives thereof Such.

(15) α-hydroxy acids, glycolic acid, citric acid, malic acid, tartaric acid, lactic acid and the like.

(16) Inorganic pigments silicic anhydride, magnesium silicate, talc, kaolin, bentonite, mica, titanium mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, calcium carbonate, magnesium carbonate, yellow iron oxide, Bengala, black iron oxide, gunjo, chromium oxide, chromium hydroxide, carbon black, calamine, etc.

(17) UV absorber / blocker benzophenone derivatives (2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid sodium salt, dihydroxy Dimethoxybenzophenone, dihydroxydimethoxybenzophenone-sodium sulfonate, 2,4-dihydroxybenzophenone, tetrahydroxybenzophenone, etc.), p-aminobenzoic acid derivatives (paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, paradimethylaminobenzoic acid) Amyl, octyl paradimethylaminobenzoate, etc.), methoxycinnamate derivatives (ethyl paramethoxycinnamate, isopropyl paramethoxycinnamate, paramethoxycinnamate) Octyl acid, 2-ethoxyethyl paramethoxycinnamate, sodium paramethoxycinnamate, potassium paramethoxycinnamate, diparamethoxycinnamate mono-2-ethylhexanoate glyceryl, etc.), salicylic acid derivatives (octyl salicylate, salicylphenyl, homomenthyl salicylate, dipropylene salicylate) Glycol, ethylene glycol salicylate, myristyl salicylate, methyl salicylate, etc.), anthranilic acid derivatives (such as methyl anthranilate), urocanic acid derivatives (such as urocanic acid, ethyl urocanate), coumarin derivatives, amino acid compounds, benzotriazole derivatives, tetrazole derivatives , Imidazoline derivatives, pyrimidine derivatives, dioxane derivatives, camphor derivatives, furan derivatives, pyrone derivatives, nucleic acid derivatives Allantoin derivatives, nicotinic acid derivatives, vitamin B6 derivatives, umbelliferone, esculin, benzyl cinnamate, cinoxalate, oxybenzone, dioxybenzone, octabenzone, soribenzone, benzoresorcinol, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, neoheliopan, Escalol, zinc oxide, talc, kaolin, etc.

(18) Whitening agent: p-aminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound, benzotriazole derivative, tetrazole derivative, imidazoline derivative, pyrimidine derivative, dioxane derivative, camphor derivative, furan derivative, Pyrone derivative, nucleic acid derivative, allantoin derivative, nicotinic acid derivative, vitamin C or its derivative (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), vitamin E or its derivative, kojic acid or its derivative, naphthol or its derivative Naphthol glycosides or derivatives thereof, oxybenzone, benzophenone, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, placenta extract, ellagic acid, lucinol and the like.

(19) Tyrosinase activity inhibitor: vitamin C or a derivative thereof (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), hydroquinone or a derivative thereof (hydroquinone benzyl ether, etc.), kojic acid or a derivative thereof, naphthol or a derivative thereof, Naphthol glycoside or derivative thereof, vitamin E or derivative thereof, N-acetyltyrosine or derivative thereof, glutathione, hydrogen peroxide, zinc peroxide, placenta extract, ellagic acid, arbutin, lucinol, silk extract, plant extract (camomile , Mulberry, touki, firewood, clara, mugwort, honeysuckle, yellowfin, dolphin, matsuhod, barley, nettle, hops, hawthorn, eucalyptus, yarrow, artea, keihi, mankei, hamamelis, yamagwa Life-extending grass, bellflower, toshishi, sequel, shot dried, mahuang, senkyu, dokatsu, psycho, boufu, hamboufu, gongo, peony, peonies, genus shochu, kurkon, licorice, pentaploid, aloe, shouma, safflower, green tea, tea, Asen).

(20) Melanin pigment reduction / decomposition substance: phenylmercury hexachlorophene, mercuric oxide, mercuric chloride, hydrogen peroxide, zinc peroxide, hydroquinone or its derivative (hydroquinone benzyl ether), vitamin C or its derivative ( Vitamin C phosphate magnesium salt, vitamin C glucoside) and the like.

(21) Turnover promoting action / cell activator: hydroquinone, lactic acid bacteria extract, placenta extract, ganoderma extract, vitamin A, vitamin E, allantoin, spleen extract, thymus extract, yeast extract, fermented milk extract, plant extract (aloe , Ogon, Horsetail, Gentian, Burdock, Sikon, Carrot, Clam, Hop, Yokuinin, Odorikosou, Semburi, Toki, Ginseng, Achacha, Hypericum, Cucumber, Pleurotus, Rosemary, Parsley).

(22) Astringent: succinic acid, allantoin, zinc chloride, zinc sulfate, zinc oxide, calamine, zinc p-phenolsulfonate, potassium aluminum sulfate, resorcin, ferric chloride, tannic acid (including catechin compounds) and the like.

(23) Active oxygen scavenger: SOD, catalase, glutathione peroxidase and the like.

(24) Antioxidant: Vitamin C or a salt thereof, stearic acid ester, vitamin E or a derivative thereof, nordihydrogua ceretenoic acid, butylhydroxytoluene (BHT), butylhydroxyanisole (BHA), hydroxytyrosol, parahydroxy Anisole, propyl gallate, sesamol, sesamorin, gossypol, etc.

(25) Lipid peroxide production inhibitor: β-carotene, plant extract (sesame culture cell, hamcha, hypericum, clam, clove, melissa, birch, birch, sage, rosemary, nanjimi, agetsu, ginkgo, green tea), etc. .

(26) Anti-inflammatory agents: ictamol, indomethacin, kaolin, salicylic acid, sodium salicylate, methyl salicylate, acetylsalicylic acid, diphenhydramine hydrochloride, d-camphor, dl-camphor, hydrocortisone, guaiazulene, camazulene, chlorpheniramine maleate, glycyrrhizic acid or Its salt, glycyrrhetinic acid or its salt, licorice extract, sicon extract, age extract, allantoin, etc.

(27) Antibacterial / bactericidal / disinfectant: Acrinol, sulfur, calcium gluconate, chlorhexidine gluconate, sulfamine, mercurochrome, lactoferrin or hydrolyzate thereof, alkyldiaminoethylglycine chloride solution, triclosan, sodium hypochlorite, chloramine T , Salicy powder, iodine compound, iodoform, sorbic acid or salts thereof, salicylic acid, dehydroacetic acid, parahydroxybenzoic acid esters, undecylenic acid, thiamine lauryl sulfate, thiamine lauryl nitrate, phenol, cresol, p-chlorophenol, p -Chloro-m-xylenol, p-chloro-m-cresol, thymol, phenethyl alcohol, o-phenylphenol, Irgasan CH3565, halocarban, hexachlorophene, chlorohex Gin, ethanol, methanol, isopropyl alcohol, benzyl alcohol, ethylene glycol, propylene glycol, phenoxyethanol, chlorobutanol, isopropylmethylphenol, nonionic surfactant (polyoxyethylene lauryl ether, polyoxyethylene nonylphenyl ether, polyoxyethylene octyl Phenyl ether, etc.), amphoteric surfactants, anionic surfactants (sodium lauryl sulfate, potassium lauroyl sarcosine, etc.), cationic surfactants (cetyltrimethylammonium bromide, benzalkonium chloride, benzethonium chloride, methylrosaniline chloride), formaldehyde, Hexamine, brilliant green, malachite green, crystal violet, jamal, photosensitizer 01 No., photosensitizer No. 201, photosensitizer No. 401, N- long chain acyl basic amino acid derivative and its acid shark salts, zinc oxide, hinokitiol, etc. sophora root.

(28) Moisturizer: glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, hyaluronic acid or its salt, polyethylene glycol, chondroitin sulfate or its salt, water-soluble chitin or chitosan derivative, pyrrolidone carboxylic acid or its salt , Sodium lactate, mini sasanishiki extract, natto bacteria metabolite, natto extract and so on.

(29) Elastase activity inhibitors: diisopropyl fluorophosphate, plant extracts (hypericum, clara, mulberry leaves, keihi, genokosho, comfrey, sage, elderberry, bodaiju, buttonpi), seaweed extract and the like.

(30) Hair preparation: selenium disulfide, alkylisoquinolinium bromide solution, zinc pyrithione, biphenamine, thianthol, castari tincture, pepper tincture, red pepper tincture, quinine hydrochloride, strong aqueous ammonia, potassium bromate, sodium bromate, Such as thioglycolic acid.

(31) Antiandrogen: follicular hormone (estrone, estradiol, ethinyl estradiol, etc.), isoflavone, oxendron, etc.

(32) Peripheral vascular blood flow promoter: Vitamin E or derivatives thereof, assembly extract, garlic extract, carrot extract, aloe extract, gentian extract, cephalanthin, carpronium chloride, minoxidil and the like.

(33) Local stimulants: chili pepper tincture, capsaicin, capsaicin glycoside, nonyl acid vanillamide, cantalis tincture, ginger tincture, peppermint oil, l-menthol, camphor, benzyl nicotinate and the like.

(34) Metabolic active agents: Photosensitive element 301, hinokitiol, pantothenic acid or derivatives thereof, allantoin, placenta extract, biotin, pentadecanoic acid glyceride and the like.

(35) Antiseborrheic agents: pyridoxine or derivatives thereof, sulfur, vitamin B6 and the like.

(36) Keratolytic agents: resorcin, salicylic acid, lactic acid and the like.

(37) Bath sensation agent: sodium bicarbonate, sodium carbonate, sodium sesquicarbonate, sodium sulfate, dry sodium sulfate, anhydrous sodium sulfate, anhydrous silicic acid, calcium silicate, and the like.

(38) Fragrance: Natural animal fragrance such as musk, civet, castorium, ambergris, anise essential oil, angelica essential oil, ylang ylang essential oil, iris essential oil, fennel essential oil, orange essential oil, cananga essential oil, caraway essential oil, cardamom essential oil, guayakwood essential oil , Cumin essential oil, black letter essential oil, cinnamon essential oil, cinnamon essential oil, geranium essential oil, copaiba balsam essential oil, coriandel essential oil, perilla essential oil, cedarwood essential oil, citronella essential oil, jasmine essential oil, gingergrass essential oil, cedar essential oil, spearmint essential oil, western peppermint essential oil , Otsuka perfume essential oil, tuberose essential oil, clove essential oil, orange flower essential oil, winter green essential oil, trout balsam essential oil, buttery essential oil, rose essential oil, palmarosa essential oil, persimmon essential oil, hiba essential oil, sandalwood essential oil, petitgren essential oil, bay essential oil, vetiva essential oil, Berga Plant essential oils such as coconut essential oil, peru balsam essential oil, boad rose essential oil, melamine essential oil, mandarin essential oil, eucalyptus essential oil, lime essential oil, lavender essential oil, linaloe essential oil, lemongrass essential oil, lemon essential oil, rosemary essential oil, Japanese mint mint essential oil Such. Synthetic perfume ingredients include aliphatic hydrocarbons, terpene hydrocarbons, aromatic hydrocarbons and other hydrocarbons, aliphatic alcohols, terpene alcohols, aromatic alcohols and other alcohols, aliphatic ethers, aromatic ethers and other ethers Oxides, aliphatic oxides, terpene oxides, aliphatic aldehydes, terpene aldehydes, hydrogenated aromatic aldehydes, aldehydes such as thioaldehydes, aromatic aldehydes, aliphatic ketones, terpene ketones, hydrogenated aromatics Ketones such as aromatic ketones, aliphatic cyclic ketones, non-benzene aromatic ketones, aromatic ketones, acetals, ketals, phenols, phenol ethers, fatty acids, terpene carboxylic acids, hydrogenated aromatic carboxylic acids, Acids such as aromatic carboxylic acids, acid amides, aliphatic lactones Lactones such as cyclic lactones, terpene lactones, hydrogenated aromatic lactones, aromatic lactones, aliphatic esters, furan carboxylic acid esters, aliphatic cyclic carboxylic acid esters, esters such as aromatic carboxylic acid esters, Nitrogen-containing compounds such as nitromusks, nitriles, amines, pyridines, quinolines, pyrrole and indole. More specific examples of synthetic fragrances include, for example, 1996 published by Chemical Industry Daily, Motoichi Into (Synthetic fragrance chemistry and product knowledge), 1969, by Stefan Arcamder (Perfume and Flavor Chemicals <Perfume and) Flavors described in Flavor Chemicals>) and the like can be suitably used. The main fragrances are shown below. Aldehyde C6-C12, anisaldehyde, acetal R, acetophenone, acetyl cedrene, adoxal, allyl amyl glycolate, allyl cyclohexane propionate, alpha damascon, beta damascon, delta damascon, ambrette lid, ambroxan, amyl Cinnamic aldehyde, amyl cinnamic aldehyde dimethyl acetal, amyl valericate, amyl salicylate, isoamyl acetate, isoamyl salicylate, uranium thiol, acetyl urgenol, bacdanol, benzyl acetate, benzyl alcohol, benzyl salicylate, bergamyl acetate, bornyl acetate , Butyl butyrate, para tertiary butyl cyclohexanol, para tertiary butyl Chlohexyl acetate, ortho-tertiary butylcyclohexanol, benzaldehyde, benzyl formate, potassium olefin, cashemalan, carvone, cedro amber, cedryl acetate, cedrol, cerythrid, cinnamic alcohol, cinnamaldehyde, cis jasmon, citral, citral Dimethyl acetal, citrusal, citronellol, citronellyl acetate, citronellyl formate, citronellyl nitrile, cyclaset, cyclamenaldehyde, cyclaprop, caron, coumarin, cinnamyl acetate, delta C6-C13 lactone, dimethylbenzyl carbinol, dihydrojasmon , Dihydrolinalol, dihydromyrcenol, dimethol, dimyrcetol, di Enyl oxide, ethyl vanillin, eugenol, fluitate, fenthyl alcohol, phenylethylphenyl cetate, galakisolid, gamma C6-C13 lactone, geraniol, geranyl acetate, geranyl formate, geranyl nitrile, hedion, helional, heliotropin, cis-3- Hexenol, cis-3-hexenyl acetate, cis-3-hexenyl salicylate, hexyl cinnamamic aldehyde, hexyl salicylate, hyacinth dimethyl acetal, hydrotropic alcohol, hydroxy citronellal, indole, innon, isobornyl acetate, isocyclo Citral, iso-E super, isoyuugenol, isononyl acetate, isobutyl quinoline, jasmar, di Examples include jasmolactone, jasmofilan, coabon, ligustral, lyial, lime oxide, limonene, linalool, linalool oxide, and linalyl acetate.

(39) Dye: Colorant Red cabbage dye, red rice dye, red dye, anato dye, scum dye, turmeric dye, enju dye, krill dye, amber dye, caramel, gold, silver, gardenia dye, corn dye, onion dye , Tamarind pigment, spirulina pigment, buckwheat whole plant pigment, cherry pigment, laver pigment, hibiscus pigment, grape juice pigment, marigold pigment, purple potato pigment, purple yam pigment, lac pigment, rutin etc.

  Others, hormones, sequestering agents, pH adjusters, chelating agents, antiseptic / antibacterial agents, cooling agents, stabilizers, emulsifiers, animal / plant proteins or their degradation products, animal / plant polysaccharides or the like Degradation products, animal / plant glycoproteins or their degradation products, anti-inflammatory agents / antiallergic agents, wound treatment agents, foams / foaming agents, thickeners, oral preparations, deodorants / deodorants, enzymes, etc. In combination with these, various additive or synergistic effects can be expected.

  The cosmetic composition, bath preparation composition, and detergent composition of the present invention are liquid, emulsion, base, gel, powder (powder), granule, pellet, stick, solid, etc., respectively. It may be provided as any form.

  Cosmetic compositions include lotion, milky lotion, cream, oil, ointment, pack, lip, lipstick, foundation, eyeliner, blusher, mascara, eye shadow, nail polish / pedicure, nail coating, nail coating removal Agent, shaving agent, shampoo, rinse, hair treatment, hair tonic, hair spray, hair cream, hair lotion, hair conditioner, hair restorer, permanent liquid, hair dye, hand soap / body soap, toothpaste, mouthwash , Facial cleansers and soaps.

  The bath agent composition is used by bathing in bath water at the time of bathing, and may be in any form such as liquid, powder, granule, solid or gel. In the case of powder, granule or solid, it is also possible to produce the antioxidant plant extract of the present invention by spraying it in a liquid state and drying it without drying.

  Examples of the detergent composition include daily kitchen detergent, bathroom, basin or toilet detergent, glass cleaner, glasses / contact lens cleaner, car cleaner, and building material cleaner.

  In addition, it can be impregnated in sanitary goods, wet type tissue paper, non-woven fabric, paper towel, cotton and the like.

  In the cosmetic composition and the detergent composition of the present invention, the skin texture improver contains about 0.001 to 5% by mass, preferably about 0.01 to 1% by mass as a dry extract. And good effects can be obtained. Moreover, in a bath agent composition, it can be used at 0.001-99 mass%, Preferably when it contains 0.1-30 mass%, usability is good and a favorable result is obtained. The amount used in one batch may be set so that the concentration in the hot water when actually used is 0.00001 to 0.01% by mass, preferably about 0.0005 to 0.005% by mass.

  The production examples, test examples, and formulation examples will be described below, but the present invention is not limited thereto.

[Example 1]
Add 500 mL of water to each mixture of unseiin, ie 4 g of Toki, 3 g of Peonies, 3 g of Senkaku, 4 g of Ziou, 1.5 g of Auren, 1.5 g of Ogaku, 3 g of Ogon, and 2 g of sushi. Extracted. Subsequently, this was filtered to obtain an extract, and further concentrated and dried to obtain 7 g of a brown powdery extract of the present invention.

[Example 2]
Add 500 liters of water to each mixture of herbal medicines, ie 4 kg of Toki, 3 kg of peony, 3 kg of peony, 4 kg of peony, 1.5 kg of owl, 1.5 kg of oyster, 3 kg of ugone, 2 kg of sushi Extracted. Subsequently, this was filtered to obtain an extract, and further concentrated and dried to obtain 5.5 kg of a brown powdery extract of the present invention.

[Example 3]
Each ingredient of Unseiin, namely 4g of Toki, 3g of Peonies, 3g of Senkyu, 4g of Diou, 1.5g of Ouren, 1.5g of Ogaku, 3g of Ogon, 2g of Sanshishi, 500 mL of 40% ethanol aqueous solution was added, Extraction at reflux for 1 hour. Next, this was filtered to obtain 450 mL of an extract.

[Comparative Example 1]
To 4 g of Toki, 90 mL of a 40% ethanol aqueous solution was added, followed by reflux extraction for 1 hour. Next, this was filtered to obtain 80 mL of an extract.

[Comparative Example 2]
70 mL of 40% ethanol aqueous solution was added to 3 g of peony, followed by reflux extraction for 1 hour. Next, this was filtered to obtain 63 mL of an extract.

[Comparative Example 3]
To 3 g of Senkyu, 70 mL of 40% ethanol aqueous solution was added, followed by reflux extraction for 1 hour. Next, this was filtered to obtain 63 mL of an extract.

[Comparative Example 4]
To 4 g of Diou, 90 mL of a 40% aqueous ethanol solution was added and refluxed for 1 hour. Next, this was filtered to obtain 80 mL of an extract.

[Comparative Example 5]
35 mL of 40% ethanol aqueous solution was added to 1.5 g of aurene, followed by reflux extraction for 1 hour. Subsequently, this was filtered and 32 mL of extract liquid was obtained.

[Comparative Example 6]
To 1.5 g of buckwheat, 35 mL of 40% ethanol aqueous solution was added, followed by reflux extraction for 1 hour. Subsequently, this was filtered and 33 mL of extract liquid was obtained.

[Comparative Example 7]
70 mL of 40% ethanol aqueous solution was added to 3 g of orgone, followed by reflux extraction for 1 hour. Next, this was filtered to obtain 63 mL of an extract.

[Comparative Example 8]
40 mL of 40% ethanol aqueous solution was added to 2 g of Sanshishi, followed by reflux extraction for 1 hour. Subsequently, this was filtered and 35 mL of extract liquid was obtained.

[Comparative Example 9]
80 mL of Toki extract of Comparative Example 1, 63 mL of Peony extract of Comparative Example 2, 63 mL of Sensu extract of Comparative Example 3, 80 mL of Diou extract of Comparative Example 4, 33 mL of Ouren extract of Comparative Example 5, Ouba of Comparative Example 6 33 mL of the extract, 63 mL of the Ogon extract of Comparative Example 7 and 35 mL of the Sanshishi extract of Comparative Example 8 were mixed to obtain 450 mL of the extract mixture of Comparative Example 9.

[Test Example 1] Safety test and evaluation of skin irritation In order to evaluate the skin irritation of the skin texture improving agent of the present invention, a patch test was conducted by monitors of 45 healthy persons (men and women aged 24 to 58). .
(Sample) Skin texture improving agent obtained in Examples 1 and 2 swollen with purified water (Method) Skin sensitization test tape “Fin Chamber” (manufactured by Taisho Pharmaceutical Co., Ltd.) was used for each sample. The occlusal side of the upper arm and the inner side of the forehead were subjected to occlusion for 24 hours for determination. That is, the sample was removed at the time when 24 hours had passed after the application, and after 1 hour, the skin condition was observed and judged, and the average value was shown in Table 1.
(Criteria) Judgment was performed according to the following criteria.
(+) Positive: Those with erythema. (±) false positive: Minor erythema or suspected erythema. (-) Negative: No reaction was observed.

  From Table 1, the skin texture improving agent according to the present invention showed no skin irritation.

[Test Example 2] Test of texture improvement effect A skin lotion was prepared using the texture improvement agent of Example 3 (Example 4), and the texture improvement effect by continuous use for 4 weeks was evaluated. As comparative controls, a lotion was prepared using the extract mixture of Comparative Example 9 (Comparative Example 10), and the texture improving agent of the present invention and the solvent used in Comparative Example 1 were replaced ( The result of measuring Comparative Example 11) under the same conditions was used.

Example 4 Lotion Formula 1
According to Formulation Example 1, a cosmetic base in which purified water is mixed with moisturizer such as 1,3-butylene glycol, glycerin, 1% sodium hyaluronate solution and preservative, ethyl alcohol in which a fragrance is dissolved at room temperature. In addition, 1.0% of the texture improving agent of the present invention was blended to prepare the lotion of the present invention.

Formulation Example 1 (Skin improver-containing lotion)
1,3-butylene glycol 3.0
Glycerin 1.0
Sorbit solution (70% solution) 0.5
1% sodium hyaluronate solution 5.0
Diethoxyethyl succinate 1.0
Preservative 0.1
Fragrance 0.1
Texture improving agent of Example 3 1.0
Purified water 88.3
Total 100.0

[Comparative Example 10] Lotion Formula 2
According to Formulation Example 2, a cosmetic base in which purified water is mixed with moisturizer such as 1,3-butylene glycol, glycerin, 1% sodium hyaluronate solution and preservative, ethyl alcohol in which a fragrance is dissolved at room temperature. In addition, 1.0% of the extract mixture of Comparative Example 9 was blended and subjected to a comparative test with the lotion of the present invention.

Formulation Example 2 (Individual Extract Extract Lotion)
1,3-butylene glycol 3.0
Glycerin 1.0
Sorbit solution (70% solution) 0.5
1% sodium hyaluronate solution 5.0
Diethoxyethyl succinate 1.0
Preservative 0.1
Fragrance 0.1
Extract liquid mixture of Comparative Example 9 1.0
Purified water 88.3
Total 100.0

[Comparative Example 11] Lotion Formula 3
According to Formulation Example 3, a cosmetic base in which purified water is mixed with moisturizer such as 1,3-butylene glycol, glycerin, 1% sodium hyaluronate solution, and preservative, ethyl alcohol in which a fragrance is dissolved at room temperature. In addition, 1.0% of 40% ethanol, which is a solvent for the extract, was blended and subjected to a comparative test with the lotion of the present invention.

Formulation Example 3 (Lotion)
1,3-butylene glycol 3.0
Glycerin 1.0
Sorbit solution (70% solution) 0.5
1% sodium hyaluronate solution 5.0
Diethoxyethyl succinate 1.0
Preservative 0.1
Fragrance 0.1
40% ethanol 1.0
Purified water 88.3
Total 100.0

  Using the texture improving agent of the present invention, the skin lotion of Example 4 was prepared, and the texture improving effect by continuous use for 4 weeks was evaluated. As a comparative control, the result of measuring the lotion of Comparative Example 10 and the lotion of Comparative Example 11 under the same conditions was used.

Method of measuring skin texture improvement effect For 16 women aged 35 to 45 years who feel dryness and itching throughout the year. Improvement of skin texture with skin lotion containing 1% skin texture improver of the present invention. The effect was investigated. The test subject was simply applied to the forearm flexion side twice a day for 4 consecutive weeks, and the texture of the test site was observed with a microscope before the start of the test and after 4 consecutive weeks of use. As a result, the number of rhomboid skins per unit area was counted and substituted into the following equation to obtain a texture score (%) from the values before the start of the test and after four consecutive weeks of use.
Kime score (%) = number of rhomboid dermis at the test site after 4 weeks of continuous use / number of rhomboid dermis at the test site before the start of the test is shown in FIG.

  From the results shown in the figure, the texture improving agent according to the present invention has an excellent texture improving effect on the mixture obtained by extracting each herbal medicine alone by mixing the herbal medicines after mixing each other. I found out.

Production of various external preparation compositions Various external preparation compositions according to the present invention were produced. Although the formulation example is shown below, this invention is not limited to these. All formulation examples are shown in parts by mass. All the skin texture improving agents of the present invention were those produced in Example 2.

[Example 5]
According to Formulation Example 4, a cosmetic base in which purified water is mixed with moisturizers such as 1,3-butylene glycol and glycerin, skin nutrients such as oleyl alcohol, preservatives, and ethyl alcohol in which a fragrance is dissolved at room temperature. To the preparation, 0.3% of the skin texture improving agent of the present invention was blended to prepare the skin lotion of the present invention.

Formulation Example 4 (Lotion)
1,3-butylene glycol 6.0
Glycerin 4.0
Oleyl alcohol 0.1
Polyoxyethylene monolaurate (20)
Sorbitan 0.5
Polyoxyethylene (15) lauryl ether 0.5
Ethyl alcohol 10.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 78.4
Total 100.0

[Example 6]
In accordance with Formulation Example 5, prepared was prepared by blending purified water with a moisturizer such as 1,3-butylene glycol and glycerin as an aqueous phase, and 0.3% of the skin texture improving agent of the present invention was blended therein. . As the oil phase part, a solid oil component such as beeswax, cetyl alcohol and petrolatum, a liquid oil component such as squalane, an oily component such as an antiseptic and a surfactant, and the mixture heated to about 80 ° C. were prepared. A thickener such as quince seed was added to the aqueous phase heated to about 80 ° C., and the oil phase was gradually added and emulsified while stirring with a homomixer to obtain the emulsion of the present invention.

Formulation Example 5 (Emulsion)
Cetyl alcohol 1.0
Beeslow 0.5
Octyldodecanol 2.0
Vaseline 2.0
Squalane 6.0
Ethyl alcohol 5.0
Glycerin 4.0
1,3-butylene glycol 4.0
Polyethylene glycol monooleate (10) 1.0
Lipophilic glyceryl monostearate 1.0
Quince Seed (Quince Seed) 1.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 72.0
Total 100.0

[Example 7]
In accordance with Formulation Example 6, as the water phase part, a purified water containing a moisturizing agent such as 1,3-butylene glycol and polyethylene glycol 1500 is prepared, and the skin texture improving agent of the present invention is added to 0.3%. % Blended. As the oil phase part, a solid oil component such as stearic acid, stearyl alcohol and hydrogenated lanolin, a liquid oil component such as squalane and octyldodecanol, and oily components such as preservatives and surfactants were prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and emulsified to obtain the cream of the present invention.

Formulation Example 6 (Cream)
Stearic acid 2.0
Stearyl alcohol 6.0
Hydrogenated lanolin 4.0
Squalane 9.0
Octyldodecanol 10.0
1,3-butylene glycol 6.0
Polyethylene glycol 1500 4.0
Polyoxyethylene (25) cetyl ether 3.0
Glycerol monostearate 2.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 53.5
Total 100.0

[Example 8]
In accordance with Formulation Example 7, a moisturizing agent such as 1,3-butylene glycol and glycerin was added to purified water, and 0.3% of the skin texture improving agent of the present invention was added thereto. This is heated to 70 to 80 ° C., a thickener such as carboxymethyl cellulose, a film agent such as polyvinyl alcohol is added and dissolved by stirring, and a solution obtained by dissolving a preservative, a surfactant, etc. in ethyl alcohol is added. Solubilized to obtain a pack of the present invention.

Formulation Example 7 (pack)
Polyvinyl alcohol 15.0
Carboxymethylcellulose 5.0
1,3-butylene glycol 4.0
Glycerin 1.0
Ethyl alcohol 12.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Polyoxyethylene oleyl ether 0.5
Purified water 62.0
Total 100.0

[Example 9]
In accordance with Formulation Example 8, the water phase part was formulated with a moisturizing agent such as 1,3-butylene glycol in purified water and 0.5% of the skin texture improving agent of the present invention. The oil phase part is prepared by mixing preservatives and surfactants with solid oils such as beeswax, paraffin wax, microcrystalline wax, higher fatty acids, semi-solids such as petrolatum and lanolin, and liquid oils such as liquid paraffin. Dissolved by heating. Next, the water phase part was heated and dissolved at 80 ° C., and the oil phase part heated to the same degree was gradually added and emulsified with stirring to obtain the ointment of the present invention. The skin texture-improving agent in the present invention is optionally blended in an external composition base. When the external composition is composed of an aqueous phase and an oil phase, it is usually blended in the aqueous phase part. It is preferred that

Formulation Example 8 (Ointment)
Beeswax 1.0
Paraffin wax 2.5
Microcrystalline wax 0.5
Stearic acid 2.0
Cetyl alcohol 1.0
Behenyl alcohol 3.0
Polyoxyethylene monostearate (20)
Sorbitan 1.0
Tetraoleic acid polyoxyethylene (60)
Sorbitan 1.0
Self-emulsifying glyceryl monostearate 1.5
Liquid paraffin 5.0
Lanolin 1.0
Vaseline 4.0
1,3-butylene glycol 5.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 70.8
Total 100.0

[Example 10]
In accordance with Formulation Example 9, as a water phase portion, purified water containing a humectant such as glycerin or urea was prepared, and 0.5% of the skin texture improving agent of the present invention was added thereto. As the oil phase part, a mixture of solid oils such as cetanol and petrolatum, liquid oils such as liquid paraffin, tocopherol acetate and vitamin D, preservatives, surfactants and other oily components was prepared. When the water phase part was gradually heated and reached about 80 ° C., the oil phase part heated to substantially the same temperature was added little by little and emulsified to obtain the hand cream of the present invention.

Formulation example 9 (hand cream)
Cetanol 4.0
Vaseline 2.0
Liquid paraffin 10.0
Tocopherol acetate 0.1
Vitamin D 0.1
Urea 2.0
Glycerin 20.0
Polyoxyethylene (60)
Glycerol isostearate 2.5
Glycerol monostearate 1.5
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 57.1
Total 100.0

[Example 11]
According to the formulation example 10, what prepared known water moisturizers, such as 1, 3- butylene glycol and polyethyleneglycol 1500, was prepared in the purified water as an aqueous phase part, and the skin texture improving agent of this invention is set to 0.0. 5% was blended. As the oil phase part, a solid oil component such as stearic acid, stearyl alcohol and glyceryl monostearate, a liquid oil component such as squalane and octyldodecanol, and oily components such as preservatives and surfactants were prepared. When the water phase is gradually heated to about 80 ° C., the oil phase heated to almost the same temperature is added little by little and emulsified to obtain a cream. To this was gradually added purified water in which potassium hydroxide was dissolved, and the mixture was saponified to obtain the face-washing cream of the present invention.

Formulation Example 10 (Fashion Cream)
Stearic acid 2.0
Stearyl alcohol 6.0
Hydrogenated lanolin 4.0
Squalane 9.0
Octyldodecanol 10.0
1,3-butylene glycol 6.0
Polyethylene glycol 1500 4.0
Polyoxyethylene (25) cetyl ether 3.0
Glycerol monostearate 2.0
Potassium hydroxide 0.5
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 52.8
Total 100.0

[Example 12]
According to Formulation Example 11, a mixture of humectants such as propylene glycol and O- [2-hydroxy-3-trimethylammoniopropyl] hydroxyethylcellulose in purified water was prepared as an aqueous phase part. 0.5% skin texture improver was added. As the oil phase part, a blend of oily components such as polyoxyethylene (2) sodium lauryl ether sulfate, sodium lauryl sulfate, coconut oil fatty acid amidopropyl betaine, highly polymerized methylpolysiloxane, ethylene glycol distearate was prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and stirred to obtain the hair shampoo of the present invention.

Formulation Example 11 (hair shampoo)
Polyoxyethylene (2) sodium lauryl ether sulfate 9.0
Sodium lauryl sulfate 4.0
Palm oil fatty acid amidopropyl betaine 3.0
Highly polymerized methylpolysiloxane 2.0
Methyl polysiloxane 1.0
Palm oil fatty acid monoethanolamide 1.0
Propylene glycol 2.0
O- [2-hydroxy-3-trimethylammoniopropyl] hydroxyethylcellulose chloride 0.5
Ethylene glycol distearate 2.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 74.8
Total 100.0

[Example 13]
According to the formulation example 12, what mixed known moisturizers, such as glycerol, with purified water as an aqueous phase part was prepared, and 0.5% of the skin texture improving agent of this invention was mix | blended with this. Contains oil components such as solid oils such as stearyltrimethylammonium chloride, stearyl alcohol and cetyl alcohol, liquid oils such as highly polymerized methylpolysiloxane, methylpolysiloxane and liquid paraffin, preservatives and surfactants as the oil phase part I prepared what I did. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion heated to almost the same temperature was added little by little and emulsified to obtain the hair rinse of the present invention.

Formulation example 12 (hair rinse)
Stearyltrimethylammonium chloride 2.0
Stearyl alcohol 1.0
Cetyl alcohol 2.0
Highly polymerized methylpolysiloxane 2.0
Methyl polysiloxane 1.0
Liquid paraffin 1.0
Glycerin 6.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 84.3
Total 100.0

[Example 14]
According to the formulation example 13, what mixed known moisturizers, such as propylene glycol and glycerol, with purified water as an aqueous phase part was prepared, and 0.5% of the skin texture improving agent of this invention was mix | blended with this. As the oil phase part, a blend of oily components such as polyoxyethylene (2) sodium lauryl ether sulfate, triethanolamine lauryl sulfate, coconut oil fatty acid amidopropyl betaine, and ethylene glycol distearate was prepared. When the water phase part was gradually heated and reached about 80 ° C., the oil phase part heated to substantially the same temperature was added little by little and stirred to obtain the body soap of the present invention.

Formulation Example 13 (Body soap)
Polyoxyethylene (2) sodium lauryl ether sulfate 15.0
Lauryl sulfate triethanolamine 5.0
Palm oil fatty acid amidopropyl betaine 5.0
Ethylene glycol distearate 2.0
Glycerol monopalmitate 1.0
Adsorption refined lanolin 2.0
Glycerin 2.0
Propylene glycol 3.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.5
Purified water 64.3
Total 100.0

[Example 15]
According to the formulation example 14, what mixed titanium oxide, antiseptic | preservative, and the fragrance | flavor was prepared for the base for soap, and 1.0% of the skin texture improving agent of this invention was mix | blended with this. This was die-cut and finished to obtain the solid soap of the present invention.

Formulation Example 14 (Soap)
Soap base 97.3
Titanium oxide 0.2
Preservative 0.5
Fragrance 1.0
Skin texture improving agent of the present invention 1.0
Total 100.0

[Example 16]
According to Formulation Example 15, a bath preparation base prepared by adding perfume and the like to sodium sulfate and sodium hydrogen carbonate is prepared, and 2.0% of the skin texture improving agent of the present invention is blended, and the bath preparation of the present invention. a.

Formulation Example 15 (Bath Agent a)
Sodium sulfate 48.0
Sodium bicarbonate 48.0
Fragrance 2.0
Skin texture improving agent of the present invention 2.0
Total 100.0

[Example 17]
According to Formulation Example 16, an oily component such as liquid paraffin, jojoba oil, or preservative was blended with a surfactant and dissolved at about 60 ° C. Fragrance, purified water and the like were added thereto, and 2.0% of the skin texture improving agent of the present invention was blended to obtain a bath preparation b of the present invention.

Formulation Example 16 (Bath Agent b)
Polyoxyethylene (5) oleyl ether 10.0
Liquid paraffin 80.0
Jojoba oil 5.0
Preservative 0.2
Fragrance 1.8
Skin texture improving agent of the present invention 2.0
Purified water 1.0
Total 100.0

[Example 18]
In accordance with Formulation Example 17, refining to a cosmetic base prepared by mixing hair nutrients such as assembly extract, tocopherol acetate, pantothenyl ethyl ether and ethyl alcohol in which preservatives, fragrances and the like are mixed at room temperature with ethyl alcohol. 0.3% of water and the skin texture improving agent of the present invention were blended to obtain the hair restorer of the present invention.

Formulation Example 17 (Hair restorer)
Ethyl alcohol 60.0
Assembly extract 5.0
Tocopherol acetate 0.2
Pantothenyl ethyl ether 0.2
Propylene glycol 5.0
Preservative 0.1
Fragrance 0.2
Skin texture improving agent of the present invention 0.3
Purified water 29.0
Total 100.0

[Example 19]
In accordance with Formulation Example 18, a mixture of known humectants such as glycerin and thickeners such as sodium carboxymethylcellulose, carrageenan, etc. in purified water as an aqueous phase is prepared, and dicalcium phosphate dihydrate, anhydrous silicic acid. Then, sodium lauryl sulfate was mixed and 0.3% of the skin texture improving agent of the present invention was blended. Sodium saccharin, a fragrance, and a preservative were added to a part of the purified water, and this was mixed and deaerated into the aqueous phase part to obtain a toothpaste of the present invention.

Formulation Example 18 (Toothpaste)
Dicalcium phosphate dihydrate 45.0
Silica anhydride 2.0
Glycerin 15.0
Sodium carboxymethylcellulose 1.0
Carrageenan 0.3
Sodium lauryl sulfate 1.5
Saccharin sodium 0.1
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 34.6
Total 100.0

[Example 20]
According to Formulation Example 19, glycerin and polyoxyethylene hydrogenated castor oil were added and dissolved in purified water. To this, 1-menthol and a fragrance dissolved in ethyl alcohol were added and mixed and dissolved. Further, sodium saccharin and chlorhexidine gluconate were added and dissolved with 0.3% of the skin texture improving agent of the present invention to prepare the mouthwash of the present invention.

Formulation Example 19 (Mouthwash)
Ethyl alcohol 40.0
Glycerin 10.0
Polyoxyethylene hydrogenated castor oil 1.0
1-menthol 0.5
Saccharin sodium 0.05
Chlorhexidine gluconate 0.02
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 48.03
Total 100.0

[Example 21]
According to the formulation example 20, what mixed polypropylene glycol, ethyl alcohol, and antiseptic | preservative in purified water was prepared as an aqueous phase part, and 0.3% of the skin texture improving agent of this invention was mix | blended with this. As an oil phase part, what mix | blended polyoxyethylene (2) sodium dodecyl sulfate, lauryl glucoside, and the fragrance | flavor oil component was prepared. When the water phase portion was gradually heated and reached about 80 ° C., the oil phase portion was added little by little and stirred to obtain the dishwashing detergent of the present invention.

Formulation Example 20 (Dishwashing detergent)
Polyoxyethylene (2)
Sodium dodecyl sulfate 15.0
Lauryl glucoside 12.5
Ethyl alcohol 5.0
Polypropylene glycol 3.0
Preservative 0.1
Fragrance 0.1
Skin texture improving agent of the present invention 0.3
Purified water 64.0
Total 100.0

  The skin texture-improving agent of the present invention is safe and comfortable to use on the skin and has a synergistic texture-improving effect, improves rough skin, restores texture to human skin that has no texture, Provides clean skin.

It is a figure which shows the improvement degree of the skin texture when the lotion using the texture improving agent of this invention and the skin lotion of a comparative example are used.

Claims (10)

  A skin texture-improving agent comprising an extract of a mixture of toki, peonies, senkyu, diou, auren, autaku, ougon and sanshishi.   0.4-10 parts of touki (mass part, the same shall apply hereinafter), 0.3-7.5 parts of peony, 0.3-7.5 parts of senkyu, 0.4-10 parts of diox, 0.2-3. A skin texture improving agent comprising an extract of a mixture of 8 parts, 0.2 to 3.8 parts of buckwheat, 0.3 to 7.5 parts of hornon, and 0.2 to 5 parts of sanshishi.   1.6 to 8 parts of Toki, 1.2 to 6 parts of peony 1.2 to 6 parts of Senkyu, 1.6 to 8 parts of Ziwu, 0.6 to 3 parts of Auren, 0.6 to 3 parts of Obakaku, Ougon 1 A skin texture improving agent comprising an extract of a mixture of 2 to 6 parts and Sanshishi 0.8 to 4 parts.   2.8-6 parts of Toki, 2.1-4.5 parts of peonies, 2.1-4.5 parts of Senkyu, 2.8-6 parts of Diou, 1.1-2.3 parts of Ouren, 1.1 A skin texture-improving agent comprising an extract of a mixture of -2.3 parts, 2.1-4.5 parts ugone and 1.4-3 parts sanshishi.   The skin texture improving agent according to any one of claims 1 to 4, which is an extract of water, alcohols or a mixture thereof.   6. The skin texture improving agent according to any one of claims 1 to 5, wherein the amount of the extraction solvent is 10 to 100 times the amount to be extracted.   A texture improving external preparation composition comprising the skin texture improving agent according to any one of claims 1 to 6.   A cosmetic composition comprising the skin texture improving agent according to any one of claims 1 to 6.   A bath composition comprising the skin texture improving agent according to any one of claims 1 to 6.   A detergent composition comprising the skin texture improving agent according to any one of claims 1 to 6.

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