KR102003717B1 - Composition for the improvement in the smell of thearmpit - Google Patents

Composition for the improvement in the smell of thearmpit Download PDF

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KR102003717B1
KR102003717B1 KR1020170065478A KR20170065478A KR102003717B1 KR 102003717 B1 KR102003717 B1 KR 102003717B1 KR 1020170065478 A KR1020170065478 A KR 1020170065478A KR 20170065478 A KR20170065478 A KR 20170065478A KR 102003717 B1 KR102003717 B1 KR 102003717B1
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이성낙
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주식회사 아주의대벤쳐메딕스
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

본 발명은 트리클로산(Triclosan)에 대한 부작용을 없애기 위하여 감초산디칼륨, 벤잘코늄클로라이드, dl-캄파, 어성초추출물, 녹차추출물, 알로에추출물 등을 함유하여 땀 악취증 증상을 개선할 수 있도록 하는 땀 악취증 증상 개선효과를 가지는 조성물에 관한 것으로, 본 발명은 에탄올 80중량부에 대하여 정제수 14.2중량부, 살리실산 0.2중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.05중량부, 감초산디칼륨 0.05중량부, 징크피씨에이 0.05중량부, 벤잘코늄클로라이드 0.05중량부, dl-캄파 0.05중량부, 라벤더오일 0.05중량부, 어성초추출물 0.05중량부, 녹차추출물 0.05중량부, 알로에추출물 0.05중량부, 키위추출물 0.05중량부를 함유한다.The present invention relates to a sweat odor enhancer which can improve sweat odor symptoms by containing dicotassium valerate, benzalkonium chloride, dl-campa, horseradish extract, green tea extract, aloe extract and the like in order to eliminate side effects on triclosan The present invention relates to a composition having symptom improvement effect, which comprises 14.2 parts by weight of purified water, 0.2 parts by weight of salicylic acid, 0.1 parts by weight of fragrance, 5 parts by weight of butylene glycol, 0.05 parts by weight of allantoin, 0.05 part by weight of zinc carbonate, 0.05 part by weight of zinc carbonate, 0.05 part by weight of benzalkonium chloride, 0.05 part by weight of dl-campa, 0.05 part by weight of lavender oil, 0.05 part by weight of hyssop, 0.05 part by weight of green tea extract, 0.05 part by weight of aloe extract, And 0.05 part by weight of the extract.

Description

땀 악취증 증상 개선효과를 가지는 조성물{Composition for the improvement in the smell of thearmpit}TECHNICAL FIELD The present invention relates to a composition for improving symptoms of sweat odor,

본 발명은 트리클로산(Triclosan)에 대한 부작용을 없애기 위하여 감초산디칼륨, 벤잘코늄클로라이드, dl-캄파, 어성초추출물, 녹차추출물, 알로에추출물 등을 함유하여 땀 악취증 증상을 개선할 수 있도록 하는 땀 악취증 증상 개선효과를 가지는 조성물에 관한 것이다.
The present invention relates to a sweat odor enhancer which can improve sweat odor symptoms by containing dicotassium valerate, benzalkonium chloride, dl-campa, horseradish extract, green tea extract, aloe extract and the like in order to eliminate side effects on triclosan And a composition having symptom improvement effect.

사람의 피부에는 약 200만개 이상의 땀샘이 분포되어 있으며, 여기에서 나오는 땀의 대부분은 에크린(Ecrine)이란 땀샘에서 분비되는데, 무색, 무취의 투명한 액체로 약간의 염분을 함유하고 있다.More than 2 million sweat glands are distributed in the human skin. Most of the sweat coming from this is secreted from the sweat glands of Ecrine, a colorless, odorless transparent liquid containing a little salt.

반면 겨드랑이, 젖가슴, 치골부위, 항문부위에 분포되어 있는 아포크린(Apocrine)이란 땀샘에서는 땀과 함께 땀샘벽에 붙어 있는 세포의 일부가 분리되어 몸 밖으로 배출(斷頭分泌:decapitation secretion)되는데, 이 배출된 단백질 성분의 세포부분이 겨드랑이에 있는 박테리아에 의하여 분해되어 생물학적 과정, 즉 부패의 결과로 불쾌한 냄새가 발생하는 것이다.On the other hand, the apocrine glands, which are distributed in the armpits, breasts, pubic area, and anal region, are separated from the sweat glands by the sweat glands and released from the body (decapitation secretion) The cellular part of the protein component is degraded by the bacteria in the armpit, resulting in an unpleasant smell as a result of the biological process, corruption.

일반적으로 자주 몸을 씻거나 또는 향료가 함유된 스프레이, 일명 데더란트를 사용하는 소극적인 방법이 있으나, 지금까지는 그 효과 면에서 크게 만족스럽지 못하였다.Generally, there is a passive method of washing the body frequently or using a spatula-containing spray, aka dodder, but so far it has not been satisfactory in terms of its effectiveness.

근래에는 레이저(Laser)를 이용하는 외과적 수술로 겨드랑이 부위에 몰려 있는 아포크린 땀샘을 제거하기도 한다. 그러나 외과적 시술은 경제적 부담이 적지 않을 뿐만 아니라, 시술 후 생길 수 있는 사회활동의 제약 등, 시간적으로도 부담이 될 수 있다. 특히 아포크린 땀샘은 겨드랑이에만 분포되어 있는 게 아니라, 젖가슴, 치골부의 등에도 분포되어 있어 외과적 시술로는 그 치료에 한계가 있다.Recently, surgical operation using laser has been used to remove the apocrine sweat glands from the armpit area. However, surgical procedures are not only economically burdensome, but also can be time-consuming, such as restrictions on social activities that may occur after the procedure. Especially, the apocrine sweat glands are distributed not only in the armpits but also in the breasts and pubes.

땀 악취증은 겨드랑이에서 발산되는 자극적이고 불쾌한 냄새를 말하며 이는 주로 겨드랑이에 산재하는 아포크린선의 분비물에 의한 것으로 분비 기능이 활발해지는 사춘기 이후에 시작된다. 냄새로 인해 특히 젊은 여성들은 사회 활동에 제약을 받게 된다. 악취증은 세균수를 감소시키고 아포크린 땀샘의 분비를 줄이면 냄새가 덜 나게 할 수 있다.Sweat stench is a stimulant and unpleasant smell that emanates from the armpits. It is caused by the secretion of apocrine glands, which spread mainly in the armpit, and it starts after puberty, when the secretory function becomes active. Because of the smell, especially young women, they are constrained by social activities. Odorosis can reduce the number of bacteria and the secretion of apocrine sweat glands to lessen the odor.

대부분 항균 비누로 씻고 항생제를 바르고, 향수를 사용하거나, 땀이 덜나게 하는 화장품 등을 사용하게 된다. 우리나라에서는 땀 악취증 정도가 심하지 않아도 냄새에 민감하게 반응하는 경향이 많으므로 대개 수술적인 치료보다는 비수술적인 방법으로 치료하는 경우가 많다.Mostly, they wash with antibacterial soap, apply antibiotics, use perfume, or use cosmetics that reduce perspiration. In Korea, there is a tendency to respond sensitively to odor even if sweat odor is not severe. Therefore, it is often treated by non - surgical method rather than surgical treatment.

그러나, 종래에 사용되어온 이러한 제제들은 큰 땀 악취 증상의 개선에 큰 효과를 보지 못하였다.
However, these prior art agents have not shown a great effect in improving the odor symptoms of large sweat.

상기한 문제점을 해결하기 위해, 본 출원인은 2003년 07월 16일자 제10-2003-0048890호(발명의 명칭 : 땀 악취증 증상 개선효과를 가지는 조성물)를 출원한 바 있으며, 청구범위는 " 에탄올 20.0∼80.0중량부, 다가알콜 5.0∼10.0중량부, 감초산 또는 그 디알칼리 금속염 0.01∼0.2중량부, 살리실산 0.1∼0.5중량부, 트리클로산 0.1∼0.5중량부, 향료에센스 0.01∼0.1중량부, 알란토인 0.1∼0.3중량부, dl-캄파 0.01∼0.1중량부, 어성초추출물 0.01∼1.0중량부, 녹차추출물 0.01∼1.0중량부, 알로에 추출물 0.01∼1.0중량부 및 물 5.0∼30.0중량부를 함유하는 땀 악취증 증상 개선효과를 가지는 조성물. " 이다.
In order to solve the above problems, the present applicant filed a patent application No. 10-2003-0048890 dated July 16, 2003 (a composition having a sweat odor symptom improvement effect) Wherein the fatty acid is at least one selected from the group consisting of 20.0 to 80.0 parts by weight of polyhydric alcohol, 5.0 to 10.0 parts by weight of polyhydric alcohol, 0.01 to 0.2 parts by weight of licorice acid or its dialkali metal salt, 0.1 to 0.5 parts by weight of salicylic acid, 0.1 to 0.5 parts by weight of triclosan, 0.01 to 1.0 part by weight of dl-campa, 0.01 to 1.0 part by weight of an extract of green tea, 0.01 to 1.0 part by weight of green tea extract, 0.01 to 1.0 part by weight of aloe extract and 5.0 to 30.0 parts by weight of water Composition having symptom improvement effect ".

그러나, 상기 땀 악취증 증상 개선효과를 가지는 조성물은 트리클로산에 대한 부작용이 발생할 수 있는 문제점이 있었다.
However, the composition having the sweat odor symptom improving effect has a problem that side effects on triclosan may occur.

따라서, 본 발명은 상기한 종래 기술에 따른 제반 문제점을 해결하기 위하여 개량발명된 것으로서, 본 발명의 목적은 트리클로산에 대한 부작용을 없애도록 한 땀 악취증 증상 개선효과를 가지는 조성물을 제공하는데 있다.
SUMMARY OF THE INVENTION Accordingly, the present invention has been made to solve the above problems occurring in the prior art, and it is an object of the present invention to provide a composition for eliminating side effects to triclosan, which has a sweat odor symptom improvement effect.

그러나 본 발명의 목적은 상기에 언급된 목적으로 제한되지 않으며, 언급되지 않은 다른 목적들은 아래의 기재로부터 당업자에게 명확하게 이해될 수 있을 것이다.
However, the object of the present invention is not limited to the above-mentioned objects, and other objects not mentioned can be clearly understood by those skilled in the art from the following description.

상기한 목적을 달성하기 위한 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물은,
에탄올 80중량부에 대하여 정제수 14.2중량부, 살리실산 0.2중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.05중량부, 감초산디칼륨 0.05중량부, 징크피씨에이 0.05중량부, 벤잘코늄클로라이드 0.05중량부, dl-캄파 0.05중량부, 라벤더오일 0.05중량부, 어성초추출물 0.05중량부, 녹차추출물 0.05중량부, 알로에추출물 0.05중량부, 키위추출물 0.05중량부를 함유한다.In order to accomplish the above object, the present invention provides a composition having sweat odor symptom improvement effect,
14.2 parts by weight of purified water, 0.2 parts by weight of salicylic acid, 0.1 parts by weight of fragrance, 5 parts by weight of butylene glycol, 0.05 parts by weight of allantoin, 0.05 parts by weight of potassium dicarboxylate, 0.05 parts by weight of zinc oxide, 0.05 part by weight of dl-camphor, 0.05 part by weight of lavender oil, 0.05 part by weight of horseradish extract, 0.05 part by weight of green tea extract, 0.05 part by weight of aloe extract and 0.05 part by weight of kiwi extract.

삭제delete

이상에서 상술한 바와 같이 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물은 감초산디칼륨, 벤잘코늄클로라이드, dl-캄파, 어성초추출물, 녹차추출물, 알로에추출물 등을 함유함으로써, 트리클로산에 대한 부작용을 없애는 효과가 있다.As described above, the composition having sweat odor symptom improvement effect according to the present invention contains side effects of triclosan by containing dicaprylate, benzalkonium chloride, dl-campa, Horseshoe extract, green tea extract and aloe extract. It has the effect of eliminating.

이로 인해, 본 발명은 땀 악취증 증상을 개선하는 효과가 있다.
Therefore, the present invention has an effect of improving symptoms of sweat odor.

이하, 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물의 바람직한 실시 예를 설명한다.Hereinafter, preferred embodiments of the composition having sweat odor symptom improvement effect according to the present invention will be described.

하기에서 본 발명을 설명함에 있어서, 관련된 공지 기능 또는 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명을 생략할 것이다.
In the following description of the present invention, detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물은 에탄올, 정제수, 살리실산, 향료, 부틸렌글라이콜, 알란토인, 감초산디칼륨, 징크피씨에이, 벤잘코늄클로라이드, dl-캄파, 라벤더오일, 어성초추출물, 녹차추출물, 알로에추출물 및 키위추출물을 함유한다.
The composition having sweat odor symptom improvement effect according to the present invention may be at least one selected from the group consisting of ethanol, purified water, salicylic acid, fragrance, butyleneglycol, allantoin, dipalmitoylcholate, zinc picia, benzalkonium chloride, dl-campa, lavender oil, , Green tea extract, aloe extract and kiwi extract.

상기 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물을 좀 더 자세하게 설명하면,The composition having the sweat odor symptom improvement effect according to the present invention will be described in more detail.

상기 에탄올은 에틸알코올이라고도 하며 술의 주성분이라고 하여 주정으로도 불린다. 분자식 C2H6O이다. 사슬모양 탄화수소는 지방족 탄화수소라고도 하며 탄소의 수에 따라 붙여지는 이름도 달라진다.The ethanol is also referred to as ethyl alcohol and is called the alcohol as the main component of alcohol. The molecular formula is C 2 H 6 O. Chain-like hydrocarbons are also called aliphatic hydrocarbons, and their names depend on the number of carbons.

그리고, 상기 에탄올은 지방족 탄화수소 화합물 중 탄소 원자가 두 개인 에테인(C2H6)에 수소 원자가 하이드록시기(-OH)로 치환된 화합물로 지방족 탄화수소 유도체이다. 무색이고 독특한 향기가 나는 액체로 녹는점은 -114℃, 끓는점은 78℃이며 마취성이 있다.The ethanol is an aliphatic hydrocarbon derivative in which a hydrogen atom is replaced with a hydroxyl group (-OH) in ethane (C 2 H 6 ) having two carbon atoms in the aliphatic hydrocarbon compound. It is colorless and has a unique aroma-melting point of -114 ° C, boiling point of 78 ° C and anesthetic.

그리고, 상기 에탄올은 합성음료, 용제, 연료, 부동제, 유기합성의 중간제로 사용되고, 높은 농도에서 소독제로 사용된다.The ethanol is used as a synthetic drink, a solvent, a fuel, an antifreeze, an intermediate for organic synthesis, and used as a disinfectant at a high concentration.

따라서, 에탄올 80중량부를 얻는다.
Thus, 80 parts by weight of ethanol is obtained.

그리고, 정제수를 에탄올 80중량부에 대하여 10.0∼15.0중량부를 얻는다.
Then, 10.0 to 15.0 parts by weight of purified water is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 살리실산은 산성이면서 페놀이기도 하므로 염화철(Ⅲ) 수용액을 가하면 보라색을 띤다.Since salicylic acid is acidic and phenol, it is purple when it is added with an aqueous solution of iron (III) chloride.

에스터의 형태로 대부분의 정유(精油) 속에 함유되어 있는데, 특히 석남과(石南科) 가울테리아속(Gaultheria屬) 잎의 향유는 살리실산메틸이 주성분이기 때문에 건조한 나트륨페녹시드와 이산화탄소를 가열·가압하여 반응시키면 생긴다.It is contained in most essential oils in the form of esters. In particular, since the fragrance of leaves of Gaultheria leaves is mainly composed of methyl salicylate, the dried sodium phenoxide and carbon dioxide are heated and pressurized .

그리고, 상기 살리실산은 해열·진통의 작용을 지니고 있으므로 나트륨염이나 칼슘염으로 내복하며, 또 각종 약물에 결합시켜 용해성·안정성·약리성 등을 개량하는 데 쓰인다.The above-mentioned salicylic acid has a function of antipyretic and analgesic, so it is used as sodium salt or calcium salt, and it is used to improve solubility, stability and pharmacological properties by binding to various drugs.

그리고, 상기 살리실산은 각질의 병적인 증식(사마귀·티눈)을 제거하기 위한 고약으로 사용되고, 메틸에스터는 외용 도포약으로 진통·소염 등에, 페닐에스터는 장·요도 등의 방부제로 사용된다.The above-mentioned salicylic acid is used as a plaster to remove pathological growth (warts, corns) of keratin. The methyl ester is used as an external application medicament, and it is used as analgesic and anti-inflammation, and phenyl ester is used as a preservative such as enteric and urethral.

따라서, 상기 살리실산을 에탄올 80중량부에 대하여 0.1∼0.5중량부를 얻는다.
Accordingly, 0.1 to 0.5 parts by weight of salicylic acid is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 향료는 향내를 내는 물질이다.The fragrance is a fragrant substance.

따라서, 오렌지, 레몬, 아니솔, 유게놀, l-카르본, 쿠마린, 제라니올, 시트랄, 시트로넬, 바닐린, 노나락톤, 보르네올, 말톨, 멘톨, 리모넨, 카모마일, 클라리세이지, 베르가몬, 만다린, 로즈마리, 월계수 중에서 선택하여 향료를 에탄올 80중량부에 대하여 0.1∼0.5중량부를 얻는다.
Thus, it is possible to use the compositions of the present invention in the form of tablets or capsules, such as oranges, lemons, anisols, yugenol, l-carbohydrates, coumarins, geranols, citrals, citrons, vanillins, nonalactone, borneol, maltol, menthol, limonene, chamomile, Bergamone, mandarin, rosemary and laurel water, and 0.1 to 0.5 parts by weight of perfume is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 부틸렌글라이콜은 부틸렌글리콜로 불리기도 한다. 화장품의 용제로 주로 사용되며, 화장품 구성 성분을 용해시키는 역할을 한다. 수분을 끌어 당기는 기능이 있어 보습제로 사용된다. 주로 보습제, 피부컨디셔닝제, 용제, 점도감소제, 향료로 사용되고 있다.The butylene glycol is also referred to as butylene glycol. It is mainly used as a solvent for cosmetics and serves to dissolve cosmetic components. It is used as a moisturizer because it has the ability to attract moisture. They are mainly used as moisturizers, skin conditioners, solvents, viscosity reducers, and perfumes.

따라서, 상기 부틸렌글라이콜을 에탄올 80중량부에 대하여 5∼10중량부를 얻는다.
Therefore, 5 to 10 parts by weight of butylene glycol is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 알란토인은 주로 여러해살이 풀인 캄프리(comfrey), 상수리나무, 밀의 싹 등에서 추출한 천연물질이다. 고분자유기물을 분해하여 저분자 물질로 만드는 과정인 이화작용에 의해 생성된 요산 산화물을 정제해 얻는다.And, the allantoin is a natural substance extracted mainly from perennial grasses such as comfrey, oak, and wheat. The uric acid oxide produced by the curing process, which is a process of decomposing the polymer organic material into a low-molecular substance, is purified.

상기 알란토인은 산세포와 죽은 세표 사이의 세포간질에 함수를 증가시켜 각질을 제거하고, 피부에 수분을 주어 피부를 부드럽게 하며 세포의 분아 번식을 증진시켜 피부의 상처에 치유를 돕는다. 또, 자극과 항원에 민감한 피부를 보호하는 효과가 있다. 가렴증이나 아토피 치료에 스테로이드 요법이 아닌 치료제로 사용된다.The allantoin increases the function of the cell epilepsy between the acid cells and the dead skin cells to remove the keratin, moistens the skin by giving moisture to the skin, and promotes the reproductive growth of the cells to help heal the wounds of the skin. In addition, it has the effect of protecting skin that is sensitive to stimulation and antigen. It is used as a remedy, not a steroid therapy, for the treatment of gallstones or atopy.

그리고, 상기 알란토인은 생화학적 재처리를 통하여 신진대사를 촉진시키는 약이나 화장품의 성분으로 사용된다. 또한, 현재까지 알레르기나 부작용 사례가 없어 화장품의 성분으로 많이 활용되고 있다. 피부보호 작용에 효과적이어서 다른 화학성분보다 훨씬 안전한 것으로 알려졌다.And, the allantoin is used as a component of drugs or cosmetics that promote metabolism through biochemical reprocessing. In addition, there are no cases of allergies or side effects to date, and they are widely used as cosmetic ingredients. It is known to be safer than other chemical ingredients because it is effective in protecting skin.

주로 치약, 양치질 약, 등의 구강 위생제품과 샴푸, 여드름 약, 햇볕에 탄 피부 진정크림, 화장 크림 등의 화장품과 의약품에 사용된다.It is mainly used for oral hygiene products such as toothpaste, toothbrush, and shampoo, acne medicine, suntan cream, cosmetic cream and cosmetic cream.

따라서, 캄프리로부터 알란토인을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 parts by weight of allantoin is obtained from Campfire with respect to 80 parts by weight of ethanol.

그리고, 감초로부터 감초산디칼륨("감초산 또는 그 디알킬리 금속염" 이라고도 함)을 얻는바, 상기 감초는 약용식물이다. 뿌리는 적갈색으로 땅속 깊이 들어가고 줄기는 모가 지며 1m 정도 곧게 자란다. 또한, 흰털이 밀생하여 회백색으로 보이며 선점(腺點)이 흩어져 있다. 잎은 어긋나고 홀수깃꼴겹잎이다. 작은잎은 7∼17개씩이고 달걀 모양이며 끝이 뾰족하다. 작은잎의 길이는 2∼5cm, 나비 l∼3cm로 양면에 흰털과 선점이 있으며 톱니는 없다.Then, from licorice, potassium valerate of licorice (also referred to as "licorice acid or its dialkyl metal salt") is obtained, and the licorice is a medicinal plant. Roots are reddish brown and deeply penetrate into the ground. In addition, the white hairs appear to be grayish white with densely grown, and glandular dots are scattered. Leaves are alternate and odd numbered double leaf. Small leaves are 7 ~ 17 eggs, egg shaped and pointed end. The length of small leaf is 2 ~ 5cm, butterfly is l ~ 3cm and there are white feathers on both sides and there is no sawtooth.

상기 감초의 꽃은 7∼8월에 피는데 길이 1.4∼2.5cm로 보라색이며, 총상꽃차례로 잎겨드랑이에 달린다. 꼬투리는 선처럼 가늘고 긴 모양으로 활처럼 굽으며 신장형의 종자가 6∼8개씩 들어 있다. 뿌리는 단맛이나서 감미료, 한약재로 사용한다.The licorice flower blooms in July-August, and its length is 1.4-2.5cm, purple, and it hangs on the leaf axil in the sporangium. The pod is thin and long like a line and it is bent like a bow. It contains 6 ~ 8 seeds of the elongated type. The roots become sweet and used as sweeteners and herbal medicines.

따라서, 상기 감초로부터 감초산디칼륨을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, from 0.01 to 0.1 part by weight of dicumyl peroxide of licorice is obtained based on 80 parts by weight of ethanol.

그리고, 상기 징크피씨에이는 천연보습인자의 일종인 피롤리돈카르본산(2-pyrrolidone-5-carboxylic acid, PCA)의 아연염으로, 아연과 PCA의 장점을 함께 제공할 수 있는 성분이다.Zinc is a zinc salt of 2-pyrrolidone-5-carboxylic acid (PCA), which is a kind of natural moisturizing factor, and can provide zinc and PCA.

따라서, 상기 징크피씨에이를 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 part by weight of the zinc oxide is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 벤잘코늄클로라이드는 알킬벤질디메칠암모늄클로라이드의 혼합물 성분이다.And, the benzalkonium chloride is a mixture component of alkylbenzyldimethylammonium chloride.

상기 벤잘코늄클로라이드는 항균작용을 한다.The benzalkonium chloride has antibacterial activity.

따라서, 상기 벤잘코늄클로라이드를 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Accordingly, 0.01 to 0.1 part by weight of benzalkonium chloride is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 dl-캄파는 피부 감각 쪽에 작용해서 시원한 감을 준다.The dl-campa acts on the skin-sensation side and gives a cool feeling.

따라서, 상기 dl-캄파를 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 part by weight of dl-campa is obtained with respect to 80 parts by weight of ethanol.

그리고, 라벤더는 6∼9월에 연한 보라색이나 흰색으로 피고, 잎이 달리지 않은 긴 꽃대 끝에 수상꽃차례를 이루며 드문드문 달린다. 꽃·잎·줄기를 덮고 있는 털들 사이에 향기가 나오는 기름샘이 있다.And, lavender is bloomed in purple or white in June-September, and it runs sparse with inflorescence at the tip of a long peduncle without leaves. Among the fur covering the flowers, leaves, and stems, there is a fountain of oil.

향수와 화장품의 원료로 사용하고 요리의 향료로 사용할 뿐만 아니라 두통이나 신경안정을 치료하는 데도 쓴다.Used as a source of fragrance and cosmetics, not only as a flavor of cooking, but also to treat headaches and nervousness.

따라서, 상기 라벤더로부터 라벤더오일을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 part by weight of lavender oil is obtained from the above lavender to 80 parts by weight of ethanol.

그리고, 어성초는 삼백초과에 속하는 다년초로 학명은 Houttuynia Cordata이며, 이 초본의 추출물이 어성초추출물이다. 이 추출물은 해독작용, 정장작용, 청혈작용, 항균작용이 있는 것으로 알려져 있다.Houttuynia cordata is a perennial plant belonging to Saururus chinensis, and its extract is Houttuynia Cordata. This extract has been known to have detoxification, suicide, amnesia, and antimicrobial action.

따라서, 상기 어성초로부터 어성초추출물을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 part by weight of the extract of Rhododendron japonica from the Rhizosphere is obtained with respect to 80 parts by weight of ethanol.

그리고, 상기 녹차추출물은 녹차의 추출물이며, 이 추출물은 폴리페놀류, 카테킨 등이 다량 함유되어 있고, 항산화작용, 콜레스테롤 저하작용, 중성지방 상승억제, 항종양, 피부미용, 비만억제, 중금속 제거, 혈압강하효과가 있는 것으로 보고되고 있다.The green tea extract is an extract of green tea. The extract contains a large amount of polyphenols, catechins, etc., and has antioxidant activity, cholesterol lowering effect, suppression of triglyceride elevation, antitumor, skin beauty, obesity suppression, It has been reported that there is a descending effect.

따라서, 상기 녹차로부터 녹차추출물을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, the green tea extract is obtained from the green tea in an amount of 0.01 to 0.1 part by weight based on 80 parts by weight of ethanol.

그리고, 상기 알로에추출물은 알로에의 추출물로서 항염증작용, 항궤양작용, 항균작용, 건위작용, 혈액순환촉진작용, 피부보습작용, 면역조절기능이 있는 것으로 알려져 있다.The aloe extract is known to have an anti-inflammatory action, an anti-ulcer action, an antibacterial action, a cardiovascular action, a blood circulation-promoting action, a skin moisturizing action and an immunity-controlling function as an extract of aloe.

따라서, 상기 알로에로부터 알로에추출물을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Therefore, 0.01 to 0.1 part by weight of the aloe extract is obtained from the aloe with respect to 80 parts by weight of ethanol.

그리고, 키위는 다래과 덩굴성 낙엽과수이며, 양다래, 참다래라 부르기도 한다.And, kiwi is a dwarf, a dwarf deciduous leaf and a number, and it is also called a dwarf, a quince.

상기 키위는 엽산, 비타민 C, 비타민 E을 많이 함유하고 있다.The kiwi contains a lot of folic acid, vitamin C and vitamin E.

따라서, 상기 키위로부터 키위추출물을 에탄올 80중량부에 대하여 0.01∼0.1중량부를 얻는다.
Accordingly, the kiwifruit extract is obtained from the kiwi in an amount of 0.01 to 0.1 part by weight based on 80 parts by weight of ethanol.

본 조성에 함유된 성분의 함량에 따른 악취증 개선효과를 확인하기 위하여 3가지 각기 다른 조성물을 제조하여 10명의 임상 대상자에게 사용하게 한 후, 12시간 경과 후 악취증의 개선여부를 확인하는 테스트를 진행하였다. 사용한 3가지 조성 실시예는 하기 내용과 같다.
In order to confirm the effect of improving the odor intensity according to the content of the composition, three different compositions were prepared and used in 10 clinical subjects. After 12 hours, the test was performed to confirm whether the odor was improved . The three composition examples used are as follows.

본 발명에 따른 땀 The sweat according to the present invention 악취증Stench 증상 개선효과를 가지는 조성물의 제조방법의  A method for producing a composition having symptom improvement effect 제1실시예를In the first embodiment, 간단히 설명하면 다음과 같다. A brief description follows.

먼저, 에탄올을 80중량부를 얻은 후, 정제수를 에탄올 80중량부에 대하여 14.7중량부를 얻는다.
First, 80 parts by weight of ethanol is obtained, and then 14.7 parts by weight of purified water is obtained with respect to 80 parts by weight of ethanol.

그리고, 살리실산을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, 0.1 part by weight of salicylic acid is obtained with respect to 80 parts by weight of ethanol.

그리고, 향료를 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, 0.1 part by weight of the perfume is added to 80 parts by weight of ethanol.

그리고, 부틸렌글라이콜을 에탄올 80중량부에 대하여 5중량부를 얻는다.
Then, 5 parts by weight of butylene glycol was added to 80 parts by weight of ethanol.

그리고, 캄프리를 얻은 후, 상기 캄프리로부터 알란토인을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
After obtaining camphor, 0.01 part by weight of allantoin is obtained from the camphor with respect to 80 parts by weight of ethanol.

그리고, 감초를 얻은 후, 상기 감초로부터 감초산디칼륨을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
After obtaining licorice, 0.01 part by weight of divalent potassium laurate is added to 80 parts by weight of ethanol from the licorice.

그리고, 천연보습인자의 일종인 피롤리돈카르본산(2-pyrrolidone-5-carboxylic acid, PCA)로부터 징크피씨에이를 에탄올 80중량부에 대하여 0.01중량부를 얻은 후, 항균작용을 하는 벤잘코늄클로라이드를 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
Then, 0.01 part by weight of 80 parts by weight of ethanol was obtained from 2-pyrrolidone-5-carboxylic acid (PCA), which is a kind of natural moisturizing factor, and then benzalkonium chloride And 0.01 part by weight based on 80 parts by weight of ethanol.

그리고, 피부 감각 쪽에 작용해서 시원한 감을 주는 dl-캄파를 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
Then, 0.01 part by weight of dl-campa is added to 80 parts by weight of ethanol to give a cool sensation to the skin.

그리고, 라벤더를 얻은 후, 상기 라벤더로부터 라벤더오일을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
Then, after obtaining lavender, 0.01 part by weight of lavender oil is obtained from the lavender to 80 parts by weight of ethanol.

그리고, 어성초를 얻은 후, 상기 어성초로부터 어성초추출물을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
Then, after obtaining an adult herb, 0.01 part by weight of herring root extract is obtained from the adult herb with respect to 80 parts by weight of ethanol.

그리고, 폴리페놀류, 카테킨 등이 다량 함유되어 있고, 항산화작용, 콜레스테롤 저하작용, 중성지방 상승억제, 항종양, 피부미용, 비만억제, 중금속 제거, 혈압강하효과가 있는 녹차를 얻은 후, 상기 녹차로부터 녹차추출물을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
After obtaining a green tea containing a large amount of polyphenols, catechins, etc. and having an antioxidative effect, a cholesterol lowering effect, a neutral fat elevation inhibition, antitumor, skin beauty, obesity suppression, heavy metal removal and blood pressure lowering effect, Green tea extract was obtained in an amount of 0.01 part by weight based on 80 parts by weight of ethanol.

그리고, 알로에를 얻은 후, 상기 알로에로부터 알로에추출물을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
After aloe is obtained, 0.01 part by weight of the aloe extract is obtained from the aloe with respect to 80 parts by weight of ethanol.

그리고, 다래과 덩굴성 낙엽과수인 키위를 얻은 후, 상기 키위로부터 키위추출물을 에탄올 80중량부에 대하여 0.01중량부를 얻는다.
Then, after obtaining vermiculite, vine leaf, and watery kiwi, 0.01 part by weight of the kiwifruit extract is obtained from the kiwifruit with respect to 80 parts by weight of ethanol.

그리고, 상기에서 얻어진 에탄올 80중량부, 정제수 14.7중량부, 살리실산 0.1중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.01중량부, 감초산디칼륨 0.01중량부, 징크피씨에이 0.01중량부, 벤잘코늄클로라이드 0.01중량부, dl-캄파 0.01중량부, 라벤더오일 0.01중량부, 어성초추출물 0.01중량부, 녹차추출물 0.01중량부, 알로에추출물 0.01중량부 및 키위추출물 0.01중량부를 혼합한다.
Then, 80 parts by weight of the obtained ethanol, 14.7 parts by weight of purified water, 0.1 part by weight of salicylic acid, 0.1 part by weight of fragrance, 5 parts by weight of butylene glycol, 0.01 part by weight of allantoin, 0.01 part by weight of potassium dodecylsuccinate, 0.01 part by weight of benzalkonium chloride, 0.01 part by weight of dl-campa, 0.01 part by weight of lavender oil, 0.01 part by weight of ssuechae extract, 0.01 part by weight of green tea extract, 0.01 part by weight of aloe extract and 0.01 part by weight of kiwi extract.

본 발명에 따른 땀 The sweat according to the present invention 악취증Stench 증상 개선효과를 가지는 조성물의 제조방법의  A method for producing a composition having symptom improvement effect 제2실시예를In the second embodiment, 간단히 설명하면 다음과 같다. A brief description follows.

먼저, 에탄올을 80중량부를 얻은 후, 정제수를 에탄올 80중량부에 대하여 14.2중량부를 얻는다.
First, 80 parts by weight of ethanol is obtained, and 14.2 parts by weight of purified water is obtained with respect to 80 parts by weight of ethanol.

그리고, 살리실산을 에탄올 80중량부에 대하여 0.2중량부를 얻는다.
Then, 0.2 part by weight of salicylic acid is obtained with respect to 80 parts by weight of ethanol.

그리고, 향료를 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, 0.1 part by weight of the perfume is added to 80 parts by weight of ethanol.

그리고, 부틸렌글라이콜을 에탄올 80중량부에 대하여 5중량부를 얻는다.
Then, 5 parts by weight of butylene glycol was added to 80 parts by weight of ethanol.

그리고, 캄프리를 얻은 후, 상기 캄프리로부터 알란토인을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
After obtaining camphor, 0.05 parts by weight of allantoin is obtained from the camphor with respect to 80 parts by weight of ethanol.

그리고, 감초를 얻은 후, 상기 감초로부터 감초산디칼륨을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
Then, licorice was obtained, and 0.05 part by weight of divalent potassium valerate was added to 80 parts by weight of the licorice.

그리고, 천연보습인자의 일종인 피롤리돈카르본산(2-pyrrolidone-5-carboxylic acid, PCA)로부터 징크피씨에이를 에탄올 80중량부에 대하여 0.05중량부를 얻은 후, 항균작용을 하는 벤잘코늄클로라이드를 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
After obtaining 0.05 part by weight of zinc peroxide from 2-pyrrolidone-5-carboxylic acid (PCA), which is a natural moisturizing factor, in 80 parts by weight of ethanol, benzalkonium chloride 0.05 parts by weight based on 80 parts by weight of ethanol is obtained.

그리고, 피부 감각 쪽에 작용해서 시원한 감을 주는 dl-캄파를 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
Then, dl-campa, which gives a cool feeling by acting on the skin-feeling side, is obtained in an amount of 0.05 part by weight based on 80 parts by weight of ethanol.

그리고, 라벤더를 얻은 후, 상기 라벤더로부터 라벤더오일을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
Then, after obtaining lavender, 0.05 part by weight of lavender oil is obtained from the lavender to 80 parts by weight of ethanol.

그리고, 어성초를 얻은 후, 상기 어성초로부터 어성초추출물을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
Then, after obtaining an adult herb, 0.05 part by weight of an adult herb extract is obtained from the adult herb with respect to 80 parts by weight of ethanol.

그리고, 폴리페놀류, 카테킨 등이 다량 함유되어 있고, 항산화작용, 콜레스테롤 저하작용, 중성지방 상승억제, 항종양, 피부미용, 비만억제, 중금속 제거, 혈압강하효과가 있는 녹차를 얻은 후, 상기 녹차로부터 녹차추출물을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
After obtaining a green tea containing a large amount of polyphenols, catechins, etc. and having an antioxidative effect, a cholesterol lowering effect, a neutral fat elevation inhibition, antitumor, skin beauty, obesity suppression, heavy metal removal and blood pressure lowering effect, Green tea extract was obtained in an amount of 0.05 part by weight based on 80 parts by weight of ethanol.

그리고, 알로에를 얻은 후, 상기 알로에로부터 알로에추출물을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
After aloe is obtained, aloe extract is obtained from the aloe in an amount of 0.05 part by weight based on 80 parts by weight of ethanol.

그리고, 다래과 덩굴성 낙엽과수인 키위를 얻은 후, 상기 키위로부터 키위추출물을 에탄올 80중량부에 대하여 0.05중량부를 얻는다.
Then, after obtaining the seedlings and the vine leaves and the kiwi fruit, 0.05 parts by weight of the kiwifruit extract is obtained from the kiwi with respect to 80 parts by weight of ethanol.

그리고, 상기에서 얻어진 에탄올 80중량부, 정제수 14.2중량부, 살리실산 0.2중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.05중량부, 감초산디칼륨 0.05중량부, 징크피씨에이 0.05중량부, 벤잘코늄클로라이드 0.05중량부, dl-캄파 0.05중량부, 라벤더오일 0.05중량부, 어성초추출물 0.05중량부, 녹차추출물 0.05중량부, 알로에추출물 0.05중량부 및 키위추출물 0.05중량부를 혼합한다.
Then, 80 parts by weight of ethanol, 14.2 parts by weight of purified water, 0.2 parts by weight of salicylic acid, 0.1 part by weight of fragrance, 5 parts by weight of allantoin, 0.05 part by weight of allantoin, 0.05 part by weight of potassium decanoate, 0.05 part by weight of benzalkonium chloride, 0.05 part by weight of dl-campa, 0.05 part by weight of lavender oil, 0.05 part by weight of horseradish extract, 0.05 part by weight of green tea extract, 0.05 part by weight of aloe extract and 0.05 part by weight of kiwi extract.

본 발명에 따른 땀 The sweat according to the present invention 악취증Stench 증상 개선효과를 가지는 조성물의 제조방법의  A method for producing a composition having symptom improvement effect 제3실시예를In the third embodiment, 간단히 설명하면 다음과 같다. A brief description follows.

먼저, 에탄올을 80중량부를 얻은 후, 정제수를 에탄올 80중량부에 대하여 13.6중량부를 얻는다.
First, 80 parts by weight of ethanol is obtained, and 13.6 parts by weight of purified water is obtained per 80 parts by weight of ethanol.

그리고, 살리실산을 에탄올 80중량부에 대하여 0.3중량부를 얻는다.
Then, 0.3 part by weight of salicylic acid was obtained with respect to 80 parts by weight of ethanol.

그리고, 향료를 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, 0.1 part by weight of the perfume is added to 80 parts by weight of ethanol.

그리고, 부틸렌글라이콜을 에탄올 80중량부에 대하여 5중량부를 얻는다.
Then, 5 parts by weight of butylene glycol was added to 80 parts by weight of ethanol.

그리고, 캄프리를 얻은 후, 상기 캄프리로부터 알란토인을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
After the camphor is obtained, 0.1 part by weight of allantoin is obtained from the camphor with respect to 80 parts by weight of ethanol.

그리고, 감초를 얻은 후, 상기 감초로부터 감초산디칼륨을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
After obtaining licorice, 0.1 part by weight of divalent potassium laurate is added to 80 parts by weight of ethanol from the licorice.

그리고, 천연보습인자의 일종인 피롤리돈카르본산(2-pyrrolidone-5-carboxylic acid, PCA)로부터 징크피씨에이를 에탄올 80중량부에 대하여 0.1중량부를 얻은 후, 항균작용을 하는 벤잘코늄클로라이드를 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
After obtaining 0.1 part by weight of zinc peroxide from 2-pyrrolidone-5-carboxylic acid (PCA), which is a kind of natural moisturizing factor, based on 80 parts by weight of ethanol, benzalkonium chloride 0.1 part by weight is obtained with respect to 80 parts by weight of ethanol.

그리고, 피부 감각 쪽에 작용해서 시원한 감을 주는 dl-캄파를 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, dl-campa, which gives a cool feeling by acting on the skin-feeling side, is obtained in an amount of 0.1 part by weight based on 80 parts by weight of ethanol.

그리고, 라벤더를 얻은 후, 상기 라벤더로부터 라벤더오일을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, after lavender is obtained, 0.1 part by weight of lavender oil is obtained from the above lavender to 80 parts by weight of ethanol.

그리고, 어성초를 얻은 후, 상기 어성초로부터 어성초추출물을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, after obtaining an adult herb, 0.1 part by weight of an adult herb extract is obtained from the adult herb with respect to 80 parts by weight of ethanol.

그리고, 폴리페놀류, 카테킨 등이 다량 함유되어 있고, 항산화작용, 콜레스테롤 저하작용, 중성지방 상승억제, 항종양, 피부미용, 비만억제, 중금속 제거, 혈압강하효과가 있는 녹차를 얻은 후, 상기 녹차로부터 녹차추출물을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
After obtaining a green tea containing a large amount of polyphenols, catechins, etc. and having an antioxidative effect, a cholesterol lowering effect, a neutral fat elevation inhibition, antitumor, skin beauty, obesity suppression, heavy metal removal and blood pressure lowering effect, Green tea extract was obtained in an amount of 0.1 part by weight based on 80 parts by weight of ethanol.

그리고, 알로에를 얻은 후, 상기 알로에로부터 알로에추출물을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
After the aloe is obtained, 0.1 part by weight of the aloe extract is obtained from the aloe with respect to 80 parts by weight of ethanol.

그리고, 다래과 덩굴성 낙엽과수인 키위를 얻은 후, 상기 키위로부터 키위추출물을 에탄올 80중량부에 대하여 0.1중량부를 얻는다.
Then, after obtaining vermiculite and vine leaf litter and water-containing kiwi, 0.1 part by weight of the kiwifruit extract is obtained from the kiwifruit with respect to 80 parts by weight of ethanol.

그리고, 상기에서 얻어진 에탄올 80중량부, 정제수 13.6중량부, 살리실산 0.3중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.1중량부, 감초산디칼륨 0.1중량부, 징크피씨에이 0.1중량부, 벤잘코늄클로라이드 0.1중량부, dl-캄파 0.1중량부, 라벤더오일 0.1중량부, 어성초추출물 0.1중량부, 녹차추출물 0.1중량부, 알로에추출물 0.1중량부 및 키위추출물 0.1중량부를 혼합한다.
Then, 80 parts by weight of ethanol, 13.6 parts by weight of purified water, 0.3 parts by weight of salicylic acid, 0.1 part by weight of fragrance, 5 parts by weight of butylene glycol, 0.1 part by weight of allantoin, 0.1 part by weight of potassium decanoate, 0.1 part by weight of benzalkonium chloride, 0.1 part by weight of dl-camphor, 0.1 part by weight of lavender oil, 0.1 part by weight of horseradish extract, 0.1 part by weight of green tea extract, 0.1 part by weight of aloe extract and 0.1 part by weight of kiwi extract.

상기 제1실시예의 조성물, 제2실시예의 조성물, 제3실시예의 조성물을 악취증이 있는 10명의 임상 대상자의 겨드랑이 부위에 도포하고 12시간 경과 후 개선여부 진단결과,The composition of the first example, the composition of the second example, and the composition of the third example were applied to the armpit area of 10 clinical subjects who had odor, and after 12 hours,

제1실시예의 조성물The composition of the first embodiment 제2실시예의 조성물The composition of the second embodiment 제3실시예의 조성물The composition of the third embodiment 우수한 악취증 개선효과를 보임Good odor improvement effect 3명3 people 7명7 people 4명4 people 약간의 악취증 개선효과를 보임Show some odor improvement 6명6 people 3명3 people 5명5 people 개선효과 없음
No improvement
1명
1 person
0명
0 people
1명
1 person

따라서, 상기 표 1에 도시된 바와 같이, 트리클로산(Triclosan)에 대한 부작용 없이 3가지 조성물 모두 악취증 개선에 효과가 있음을 보이며, 특히 제2실시예의 조성물이 땀 악취증 증상을 빠르게 개선하는 효과가 있는 것으로 나타나고 있다.
Thus, as shown in Table 1 above, all three compositions without side effects on triclosan show an effect on improvement of odor, and in particular, the composition of the second embodiment has the effect of rapidly improving symptoms of sweat odor .

하기 표 2는 일반적인 항생제를 이용하여 겨드랑이 부위의 테스트결과를 보여주는 사진이고, 하기 표 3은 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물을 이용하여 겨드랑이 부위의 테스트결과를 보여주는 사진이다.Table 2 below shows test results of armpit area using general antibiotics, and Table 3 shows test results of axillary area using a composition having sweat odor symptom improvement effect according to the present invention.

표 2 내지 표 3를 참조하면, 추가로 악취증 원인이 되는 겨드랑이 부위의 상재균 3종에 대한 조성물의 항균력을 객관적으로 검증하기 위하여 하기와 같은 테스트를 실시하였다.Tables 2 to 3 were subjected to the following tests to objectively verify the antimicrobial activity of the composition against three kinds of supernatant bacteria in the armpit area, which is a cause of malodor.

실시기관 : 아주대 의대 세포생물학교실Performed by: Department of Cell Biology, Ajou University School of Medicine

실시목적 : 겨드랑이에 항상 존재하는 상재균 Acinetobacter calcoaceticus (KCTC 2334), Corynebacterium minutissimum (ATCC 23346), Brevibacterium sp. (KCTC 1679) 세가지는 겨드랑이 부위에서 분비되는 땀에 포함 된 단백질을 분해하며 불쾌한 냄새를 유발한다. 따라서 세가지 균에 대한 항균력을 측정하여 냄새 유발원인 균을 제거할 수 있는지 여부를 확인OBJECTIVE: To investigate the effects of Acinetobacter calcoaceticus (KCTC 2334), Corynebacterium minutissimum (ATCC 23346), Brevibacterium sp. (KCTC 1679), which break down proteins contained in the sweat secreted from the armpits and cause unpleasant odors. Therefore, by measuring the antibacterial activity against the three bacteria, it is confirmed whether or not the causative agent causing the odor can be removed

P : POSITIVE CONTROL Clindamycin Phosphate 1% 외용제 (제품명 : 듀오크린액)P: POSITIVE CONTROL Clindamycin Phosphate 1% external agent (product name: duoclein solution)

N : NEGATIVE CONTROL 정제수N: NEGATIVE CONTROL Purified water

S : 본 발명에 따른 땀 악취증 증상 개선효과를 가지는 조성물S: a composition having the sweat odor symptom improvement effect according to the present invention

A : AMPICILINE / B : BACITRACIN (일반 항생제)A: AMPICILINE / B: BACITRACIN (general antibiotic)

Acinetobacter calcoaceticus
(KCTC 2334) Acinetobacter calcoaceticus
(KCTC 2334) Corynebacterium minutissimum
(ATCC 23346)Corynebacterium minutissimum
(ATCC 23346)

Figure 112017050557239-pat00001

Figure 112017050557239-pat00001

Figure 112017050557239-pat00002
Figure 112017050557239-pat00002

Brevibacterium sp.
(KCTC 1679)Brevibacterium sp.
(KCTC 1679)

Figure 112017050557239-pat00003
Figure 112017050557239-pat00003

테스트 결과 의약품에 사용되는 항생원료와 유사한 정도의 항균력을 보이고, 냄새의 원인이 되는 겨드랑이 상재균에 대한 항균력이 뛰어나 냄새 방지효과가 뛰어날 것으로 판단된다.
As a result, the antimicrobial activity is similar to that of the antibiotic raw materials used in medicines, and the antimicrobial activity against the underarm antimicrobial bacteria, which causes the odor, is excellent.

상기 발명의 상세한 설명은 단지 본 발명의 예시적인 것으로서, 이는 단지 본 발명을 설명하기 위한 목적에서 사용된 것이지 의미 한정이나 특허청구범위에 기재된 본 발명의 범위를 제한하기 위하여 사용된 것은 아니다. 그러므로 본 기술 분야의 통상의 지식을 가진 자라면 이로부터 다양한 변형 및 균등한 타 실시예가 가능하다는 점을 이해할 것이다. 따라서 본 발명의 진정한 기술적 보호 범위는 첨부된 특허청구범위의 기술적 사상에 의해 정해져야 할 것이다.
The foregoing description of the invention is merely exemplary of the invention and is used for the purpose of illustration only and is not intended to limit the scope of the invention as defined in the claims or the claims. Therefore, those skilled in the art will appreciate that various modifications and equivalent embodiments are possible without departing from the scope of the present invention. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims.

Claims (4)

에탄올 80중량부에 대하여 정제수 14.2중량부, 살리실산 0.2중량부, 향료 0.1중량부, 부틸렌글라이콜 5중량부, 알란토인 0.05중량부, 감초산디칼륨 0.05중량부, 징크피씨에이 0.05중량부, 벤잘코늄클로라이드 0.05중량부, dl-캄파 0.05중량부, 라벤더오일 0.05중량부, 어성초추출물 0.05중량부, 녹차추출물 0.05중량부, 알로에추출물 0.05중량부, 키위추출물 0.05중량부를 함유한 것을 특징으로 하는 땀 악취증 증상 개선효과를 가지는 조성물.











14.2 parts by weight of purified water, 0.2 parts by weight of salicylic acid, 0.1 parts by weight of fragrance, 5 parts by weight of butylene glycol, 0.05 parts by weight of allantoin, 0.05 parts by weight of potassium dicarboxylate, 0.05 parts by weight of zinc oxide, 0.05 part by weight of dibenzoyl chloride, 0.05 part by weight of dl-campa, 0.05 part by weight of lavender oil, 0.05 part by weight of hyssop wasan extract, 0.05 part by weight of green tea extract, 0.05 part by weight of aloe extract and 0.05 part by weight of kiwi extract A composition having symptom improvement effect.











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Publication number Priority date Publication date Assignee Title
KR100566661B1 (en) * 2003-07-16 2006-03-31 주식회사 아주의대벤쳐메딕스 Composition for the improvement in the smell of the armpit
JP2008508189A (en) * 2004-06-03 2008-03-21 ブラウン、ジェイ．スティーブン Disinfecting composition and method for producing the same

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KR20030069391A (en) * 2002-02-20 2003-08-27 주식회사 엘지생활건강 Cosmetic compositions with anti-bacterial agents against body malodor

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100566661B1 (en) * 2003-07-16 2006-03-31 주식회사 아주의대벤쳐메딕스 Composition for the improvement in the smell of the armpit
JP2008508189A (en) * 2004-06-03 2008-03-21 ブラウン、ジェイ．スティーブン Disinfecting composition and method for producing the same

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