JP7197228B2 - multipurpose serum - Google Patents

Description

The present invention relates to a multi-purpose beauty essence, more specifically, it is effective for care of extrinsic rough skin and skin dryness, and provides skin with moisture, tension, flexibility, etc. to promote skin health from the inside, To provide a multi-purpose beauty essence that can prevent aging if young, rejuvenate skin if aged, maintain young and healthy skin, and can be used safely for a long period of time without side effects even when used continuously.

In recent years, the mechanism of damage to cells due to external stimuli (e.g., ultraviolet rays, chemical substances, air pollutants, pollen, etc.) and methods of coping with them have been elucidated in detail. There are ways to do that.
It has also been discovered how to moisturize the skin and promote the youthfulness and health of the skin. In addition, research on the mechanism of cellular senescence is also progressing.

In addition, many functional materials such as whitening agents, antioxidants, anti-inflammatory agents, UV inhibitors, cell activators, blood circulation promoters, peroxide skin quality improvement agents, and tranquilizers are incorporated into cosmetics and external skin preparations. Based on the mechanism of action of these functional ingredients, efforts have been made to promote skin health from the inside.

Among these functional materials, collagen and collagen production promoters have been attracting particular attention in recent years.
Collagen is generally considered to be a component of skin, but is actually a generic term for proteins having a primary structure in which glycine is repeated every three amino acid residues. Collagen constitutes various organs of the human body, accounts for 25-30% of the proteins present in humans, and primarily serves to give mechanical strength to connective tissue.

By the way, the skin has a three-layer structure of the epidermis, dermis, and underlying tissue, and collagen is the main component of the dermis and constitutes about 70% of the dermis. Here, the dermis is not directly visible like the epidermis, but inside the epidermis, it gives tension and elasticity to the skin to form a beautiful skin. Dermal collagen mainly has a triple helical structure and is produced from precursors in the skin. Collagen production promoters that promote collagen production are known (see, for example, Patent Document 1).

On the other hand, collagen is degraded for various reasons. It is said that the amount of collagen in the skin decreases to half of that in the 20s in the 60s, and the remaining collagen loses its flexibility. That is, the main cause is that old collagen hardens without being decomposed and new collagen produced by metabolism decreases, and this is said to be the aging phenomenon of the skin due to aging.

In addition, when the skin is exposed to ultraviolet rays, superoxide is generated, melanogen is oxidized to produce melanin, and a large number of peroxidases are produced. This peroxidase contains an enzyme that decomposes collagen, and in the skin exposed to ultraviolet rays, collagen is decomposed by the enzyme and reduced, and furthermore, due to the influence of ultraviolet rays, normal collagen is lost. It also reduces production capacity.

Peroxidative degrading enzymes produced by skin exposure to ultraviolet rays are decomposed by peroxide radical scavengers such as vitamin C and polyphenols. However, continuous exposure to ultraviolet rays causes a phenomenon called photoaging, in which all collagen in the skin is gradually oxidatively damaged, causing wrinkles and sagging. Moreover, photoaging is more severe than natural aging due to aging, and it is said that most of the causes of skin aging are UV rays. Therefore, it is said that it is effective to continuously distribute vitamin C and a peroxide radical scavenger, which have reducing properties, to the skin in order to prevent skin aging.

For the purpose of increasing the amount of collagen in the skin, for example, Patent Document 1 discloses a collagen production promoter and a collagen production gene expression promoter containing rice-derived peptides as an active ingredient. However, the effect was moderate, and it took a long time until the effect of promoting collagen production actually appeared.

Patent Document 2 describes an external preparation for skin obtained from an extract of the petals of cherry blossoms belonging to the genus Prunus of the family Rosaceae.

JP 2012-67042 A JP 2017-165727 A Japanese Patent No. 6875767

Based on the mechanism of promoting or maintaining the health of the skin, the present invention contains basic active ingredients that protect the skin from external stimuli including ultraviolet rays, air pollutants, chemical substances, etc. and a moisturizing agent that maintains healthy skin even with aging, and provides a multi-purpose beauty essence that deals with skin damage and its repair, moisturizes the skin, and promotes youthfulness and health of the skin. for the purpose.

The present invention also contains a collagen production promoting agent derived from rice extract and a whitening/antioxidant agent derived from cherry blossom extract. It has a synergistic effect of antioxidant action and aims to promote skin health and whitening from the inside of the skin.

A further object of the present invention is to provide a multi-purpose beauty essence that is organically certified using organic ingredients that are 100% naturally derived, have no side effects even when used continuously, and can be used safely over a long period of time.
Another object of the present invention is to contain natural water with small vanadium-containing clusters that springs up in mountains, has excellent skin permeability, dissolves many active substances, and is absorbed by the body along with them.

The multi-purpose beauty essence of the present invention for solving such problems is a basic active ingredient containing one or both of a vitamin C derivative and a licorice-derived dipotassium glycyrrhizinate, a maltose/sucrose condensate, and DL-pyrrolidonecarvone. A moisturizing agent containing one or both of sodium acid salts, a functional material containing a cherry extract-derived whitening/antioxidant and a rice extract-derived collagen production promoter, a plant-derived extract, and an organic Containing certified organic firming materials and vanadium-containing natural water from mountain springs, it protects the skin from extrinsic rough skin, maintains moist and healthy skin, gives skin firmness and wrinkles. It is characterized by being an external preparation that exhibits preventive and whitening/antioxidant effects.

In addition, the multi-purpose beauty essence of the present invention contains one or more selected from perilla extract, noni juice, Japanese apricot juice extract, Japanese ginger extract, peony extract, chimp extract, hikiokoshi extract, saxifrage extract, mugwort extract, tea extract, yokuinin extract, and fennel extract. It is characterized by being a plant-derived extract.

Also, in the multi-purpose beauty essence of the present invention, the organic firming material is one or more selected from aloe powder, wild rose extract, hawthorn extract, yarrow extract, sage extract, thyme extract, lavender extract, and rosemary extract. is preferred.

The multi-purpose beauty essence of the present invention contains basic active ingredients including one or both of vitamin C derivatives and dipotassium glycyrrhizinate derived from licorice, is effective against chronic dermatitis, and is effective against ultraviolet rays, air pollutants, and chemical substances. , Pollen, etc. are effective in the treatment of exogenous rough skin.

In addition, the multi-purpose beauty essence of the present invention contains a moisturizing agent containing one or both of maltose/sucrose condensate and sodium DL-pyrrolidonecarboxylate, which have anti-aging effects while moisturizing the skin. However, even if you are aging, you can maintain moist and healthy skin regardless of the age of the user.

Furthermore, the multi-purpose beauty essence of the present invention contains functional ingredients consisting of cherry blossom extract and rice extract, and by synergizing whitening and antioxidant effects due to collagen production promoting action, collagen degrading enzyme inhibiting action, and peroxide radical scavenging action, It increases collagen content from the inside of the skin, inhibits melanin synthesis, and prevents skin aging, thus maintaining skin tension and forming and maintaining soft, wrinkle-free and white skin.

Furthermore, the multi-purpose beauty essence of the present invention contains a plant-derived extract and an organic firming material, and provides a multi-purpose beauty essence using organic raw materials that can be used safely for a long period of time without side effects even when used continuously.

Furthermore, the present invention is characterized in that natural water springing up in mountains is used as a solvent. As the natural water used in the present invention, for example, Mt. Fuji spring water can be used. Mt.Fuji spring water is natural water that springs out from a specific place at an altitude of about 1000m on Mt.Fuji.It contains vanadium, which makes water clusters smaller, so it has excellent skin permeability and contains many active substances. It dissolves and accompanies to the body to absorb.

FIG. 2 shows the treatment side and placebo side of a subject in an evaluation study. FIG. 10 is a diagram showing the results of visual wrinkle analysis in an evaluation test. 2 is a graph showing the results of photographic analysis of wrinkles in an evaluation test.

The present invention will be described in detail below with reference to examples.
This description is for the purpose of explaining the present invention, and is not intended to limit the technical scope of the present invention. The present invention can be modified in various ways without departing from the technical scope of the present invention.

The multi-purpose beauty essence of the present invention comprises a basic active ingredient containing one or both of a vitamin C derivative and licorice-derived dipotassium glycyrrhizinate, and any one of maltose/sucrose condensate and sodium DL-pyrrolidonecarboxylate. Or a moisturizing agent containing both, a functional material containing both a cherry extract-derived peroxide radical scavenger having whitening and antioxidant effects and a rice extract-derived collagen production promoter, and a plant-derived extract , organic farming materials, and vanadium-containing natural mountain spring waters.

(Vitamin C derivative)
Here, vitamin C protects the skin from skin troubles such as skin inflammation, UV damage, and aging, suppresses melanin synthesis in the skin exposed to UV rays, decomposes the produced melanin, and reduces pigmentation. It has the effect of preventing and keeping the skin white. It also has an antioxidant effect, is an essential component for collagen production, and has a collagen production-promoting effect. As such, vitamin C maintains the skin's tension from the inside and has excellent effects such as whitening, smooth and elastic skin.
However, vitamin C is not absorbed by direct application to the skin, is supplied by the body in small amounts, and is unstable, easily degraded, and rapidly excreted from the skin.

In contrast, the vitamin C derivative used as the basic active ingredient of the present invention stays in the skin when administered, and is decomposed into vitamin C in the skin to maintain high vitamin C concentration and activity, thereby exhibiting excellent effects of vitamin C. are used, and examples thereof include magnesium ascorbyl phosphate, sodium ascorbyl phosphate, 3-O-ethylascorbic acid, ascorbyl glucoside, and the like.
The content of the vitamin C derivative in the multipurpose beauty essence of the present invention is preferably 5.0% by mass or less, more preferably 0.5 to 4.5% by mass.

(Dipotassium glycyrrhizinate)
In addition, dipotassium glycyrrhizinate, which is used as one of the basic active ingredients, is a major component of licorice (licorice), has anti-inflammatory and anti-allergic effects, is effective against chronic dermatitis, and treats rough skin. to maintain healthy skin. In addition, although its effect is milder than that of adrenocortical hormone and its effect is less immediate, it has fewer side effects even if it is used continuously.
The content of dipotassium glycyrrhizinate is preferably 0.5% by mass or less, more preferably 0.1 to 0.4% by mass. If dipotassium glycyrrhizinate is less than 0.1% by mass, sufficient anti-inflammatory action may not be exhibited.

The multi-purpose beauty essence of the present invention contains either one or both of the vitamin C derivative and dipotassium glycyrrhizinate described above, thereby exhibiting antioxidant action, protection from photoaging, and inhibition of ultraviolet damage. In addition, it can be used as a beauty essence that has an effect of preventing skin inflammation and pigmentation and an anti-inflammatory effect, and that these effects are long-lasting and have few side effects.

(moisturizer)
The moisturizing agent used in the present invention contains one or both of maltose/sucrose condensate and sodium DL-pyrrolidonecarboxylate.
A maltose/sucrose condensate is a tetrasaccharide obtained by enzymatically binding maltose and sucrose, and has an excellent moisturizing effect. In addition, sodium DL-pyrrolidonecarboxylate is a lactam bond of DL-glutamic acid in the molecule, and has the effect of increasing the water content of the skin.
These two types of moisturizing agents can be blended in the beauty essence of the present invention, and by blending the two types of moisturizing agents, it is possible to exhibit a well-balanced moisturizing effect on the entire skin.

The content of each of the above moisturizing agents is preferably 0.5% by mass or less (but not 0% by mass at the same time), and more preferably 0.1 to 0.4% by mass. Each of the moisturizing agents may not exhibit a sufficient moisturizing action when less than 0.1% by mass.

The multi-purpose beauty essence of the present invention further contains both a cherry blossom extract-derived whitening/antioxidant agent and a rice extract-derived collagen production promoter. The whitening/antioxidant agent and collagen production promoter used in the present invention assist the actions of the basic active ingredients and moisturizing ingredients on the skin. It assists the action of active ingredients and moisturizing agents.

(Sakura extract)
[Production Example 1]
200 g of flower buds of Satozakura of the family Rosaceae just before flowering were collected, washed with water immediately after collection, then dried in a nitrogen stream at 65 to 70°C for 1.0 hour, and dried in a nitrogen atmosphere at 50% 1,3 butylene glycol. The extract was extracted at ~70°C for 50 hours and filtered to obtain 1.5 kg of a pale green, transparent cherry blossom extract related to the whitening/antioxidant of the present invention (evaporation residue: 1.53% by mass).
A cherry leaf extract or a cherry petal extract can be obtained by a similar operation using either one of cherry blossom leaves or cherry petals instead of cherry blossom buds.

The content of the cherry flower bud extract described in Production Example 1 in the multipurpose beauty essence of the present invention is preferably 0.5% by mass or less, and preferably 0.1 to 0.4% by mass. more preferred. If the content of the cherry extract is less than 0.1% by mass, it may not exhibit sufficient action.

Patent Document 1 describes a method of drying and pulverizing Satozakura flowers, adding purified water to the pulverized product, extracting at 80° C. for 2 hours, and filtering to obtain 1385 g of a brown and transparent cherry extract solution. there is However, when plants are injured, autolytic enzymes such as polyphenol oxidase, which were previously inactive and confined in their cells, are released and activated. It is thought that such compounds are peroxidatively decomposed (see Patent Document 3).
The cherry extract solution described in Patent Document 1 does not consider this point, and the cherry extract solution described in Patent Document 1 does not decompose polyphenols, which are the active ingredients of the peroxide radical scavenging action. It is considered that it is not included.

However, even if polyphenol oxidase is activated, it cannot oxidize polyphenols in the absence of oxygen, and has the property of being decomposed and inactivated at 60-70°C. On the other hand, polyphenols are stable even at about 60-70° C. in the absence of polyphenol oxidase.
Therefore, in the present invention, the flower buds of cherry blossoms are heated to about 60 to 70 ° C. in an oxygen-free atmosphere to decompose polyphenol oxidase, and then polyphenols, which are active ingredients, are extracted. It contains a large amount of genus.
A cherry leaf extract or a cherry petal extract can be obtained by a similar operation using either one of cherry blossom leaves or cherry petals instead of cherry blossom buds.

The content of the cherry flower bud extract is preferably 0.5% by mass or less, more preferably 0.1 to 0.4% by mass. If the content of the cherry blossom extract is less than 0.1% by mass, it may not exhibit sufficient action.

(rice extract)
[Production Example 2]
Polished rice powder was suspended in distilled water, an amylolytic enzyme was added, the mixture was stirred and then cooled, and the precipitate was recovered by centrifugation. After adding water to this and stirring, it washed with water by collect|recovering precipitation using centrifugation. After that, drying was performed to obtain a rice-derived protein. Rice protein purity was 78%. 900 ml of tap water was added to 100 g of this rice protein (protein content: about 70%), and an appropriate amount of proteolytic enzyme was added for reaction. Thereafter, the enzyme was deactivated and centrifuged to obtain a rice extract related to the collagen production promoter of the present invention as a supernatant liquid (evaporation residue: 1.36% by mass).

(Natural water)
Natural water used in the present invention is used as a solvent. As this natural water, natural water containing vanadium springing up in mountains is selected. For this natural water, for example, Mt. Fuji spring water can be used. Mt.Fuji spring water is natural water that springs out from a specific place at an altitude of about 1000m on Mt.Fuji. Mt.Fuji spring water contains vanadium and the clusters of water are small, so it has excellent skin permeability, and has the effect of dissolving many active substances and absorbing them into the body.

(organic farming material)
Organic farming materials are materials used for manufacturing (organic farming) that minimizes the burden on the environment and living organisms in all processes from cultivation in the soil (organic cultivation) to finished products that reach consumers. They are agricultural products and herbs that are produced in a recycling-oriented manner without the use of pesticides and chemical fertilizers through the cooperation of producers and consumers. The present invention uses organic certification from ECOCERT, the largest organic certification organization centered on Europe.

As the organic firming material, one or more selected from aloe juice powder, wild rose extract, hawthorn extract, yarrow extract, sage extract, thyme extract, lavender extract, or rosemary extract can be used.

The aloe vera juice powder in the organic firming material is the dried powder of aloe vera leaf juice, which has a therapeutic effect on skin damage and an effect of suppressing the production of melanin. Novara extract is an extract prepared by extracting from the fruits of Novara, a plant belonging to the family Rosaceae. It contains flavonoids, tannins, vitamins, organic acids, and sugars as ingredients. Nobara extract has a moisturizing effect and an astringent effect, so it can protect the skin from dryness and maintain the skin with fine texture and firmness.

Hawthorn extract is a deciduous tree extract of the Rosaceae family native to Europe and North Africa, the leaves and flowers of which are used in folk or traditional medicine to treat heart failure. Achillea millefolium extract is an extract extracted from the flowers and leaves of the genus Seraph of the Asteraceae family, has a tonic effect, an appetite stimulating effect, a perspiration effect, and an antipyretic effect, and is drunk as a herbal tea, which is good for promoting the health of the human body. is.

Sage extract is an extract obtained by extracting from the leaves of the labiatae plant salvia. It contains a large amount of flavonoids and tannins as essential oil components, and has various functions such as promoting blood circulation and anti-inflammatory effects. It works to protect the skin. A thyme extract is an extract of the leaves of Thymus vulgaris and is blended in cosmetics for purposes such as astringent action and antibacterial action.

Lavender extract has a strong relaxing effect and an antibacterial effect, and also has the effect of activating skin cells, and is effective in improving eczema, sunburn, and age spots. Rosemary extract is a leaf extract that has antioxidant and anti-aging properties.
The content of each of the above organic farming materials is preferably 0.1% or less and the total content is 0.5% by mass or less.

The multi-purpose serum of the present invention can contain one or more natural plant-derived extracts. As the natural plant-derived extract, for example, one selected from perilla extract, noni fruit juice, Japanese apricot fruit juice extract, gennoshokou extract, peony extract, chimp extract, hikiokoshi extract, saxifrage extract, mugwort extract, tea extract, yokuinin extract, fennel extract, etc. Although the above can be selected, the plant-derived extracts that can be used in the present invention are not limited to these.

As a multi-purpose serum, perilla extract is an extract obtained by extracting from perilla leaves of the Labiatae plant perilla, and perillaldehyde, which is the main component with medicinal effects, causes contact dermatitis when applied to the skin. Therefore, perillaldehyde is removed for cosmetics. When incorporated into cosmetics, it is known to have an antiallergic action by inhibiting hyaluronidase activity, an action to improve the skin barrier by promoting the synthesis of ceramide, and an action to suppress pigmentation by inhibiting tyrosinase.

Noni juice is the fruit juice of the seeds of the genus Rhododendron of the family Rubiaceae, which is a tropical plant. Plum juice extract is an extract obtained by grating and squeezing plums, boiling down the juice over time, and boiling down 1 kg of plums to 20 to 25 g. It improves the flow, recovers from fatigue, regulates the condition of the intestines, suppresses the glycation of the skin, and suppresses dullness and loss of elasticity of the skin.

The medicinal plant extract is extracted with water from the medicinal plant belonging to the genus Geranium of the family Geranium family and boiled down, and has an intestinal regulating action. The peony extract is a solution obtained by extracting the root of peony peony, a plant belonging to the Peonaceae family, with water and ethanol.

Chimp extract is an extract extracted from the pericarp of Tachibana of the Rutaceae family, and has the effect of suppressing the production of melanin, and is used as a whitening agent. The extract is an extract obtained by extracting from the leaves and stems of the plant of the Labiatae family, and has an anti-allergic action by suppressing histamine release and inhibiting hyaluronidase activity.

The saxifrage extract is a plant-derived extract obtained from the whole plant of the saxifrage family Saxifrage, and has an effect of suppressing histamine release and pigmentation by suppressing melanin production. Mugwort extract is a plant-derived extract obtained by extracting the whole plant of Mugwort, a plant of the Asteraceae family, and has anti-glycation stress action, skin aging prevention action and pigmentation suppression action.

Tea extract is a plant-derived extract obtained by extracting from the leaves of the camellia plant tea tree, and has an antioxidant effect by suppressing hydrogen peroxide, nitric oxide production, and lipid peroxide, and a pigmentation suppressing effect. have Yokuinin extract is a plant-derived extract obtained by extracting Coix seed from the gramineous plant, and has a moisturizing effect, an anti-allergic effect, and a cell activating effect.

Fennel extract is an extract from the seeds of fennel, a plant of the Umbelliferae family, and has the action of scavenging active oxygen and the action of preventing skin aging caused by ultraviolet rays and the like.
The content of the above natural plant-derived extracts is preferably 0.1% by mass or less, and 0.5% by mass or less in total.

(Beauty essence)
Using the cherry-derived extract described in Production Example 1 of the present invention, the rice-derived extract described in Production Example 2, and cosmetic ingredients, a multi-purpose beauty essence (lotion) having a composition within the range shown in Table 1 is produced. did.
As cosmetic raw materials, one or more of 1,3-butylene glycol, diglycerin, 1,2-pentanediol, erythritol, and glycerin, which are well known to those skilled in the art, were used.
In addition, rice extract, cherry extract, organic farming materials, and plant-derived extracts are not 0%, and vitamin C derivatives and dipotassium glycyrrhizinate, and maltose/sucrose condensate and sodium DL-pyrrolidone carboxylate are used at the same time. Not 0%.

[Evaluation test]
A clinical test of the anti-wrinkle effect of the multi-purpose beauty essence of the invention was conducted using the beauty essences showing the anti-wrinkle effect shown in Table 1. As a placebo for comparison, a sample containing neither the rice extract-derived collagen production promoter nor the cherry extract-derived whitening/antioxidant agent was used.

(overview)
21 female subjects with an average age of 47.38 ± 5.25 years old with mild to moderate fine wrinkles were divided into a treatment group and a non-treatment group (placebo application), and the treatment group was treated with the present invention according to the present invention. Apply a multi-purpose serum sample, apply a placebo that does not contain a rice extract-derived collagen production promoter and a cherry extract-derived whitening/antioxidant to the untreated group, and check the wrinkles at the corners of the eyes for 4 weeks. Visual judgment, photographic judgment, and three-dimensional image analysis were performed, and a questionnaire was given to the subjects after 4 weeks of continuous treatment.

(Test method)
The subject's face is divided into left and right halves, and after washing the face, 0.5 g of the multi-purpose beauty essence sample of the present invention or placebo is applied to each corner of the eye on one side, and lightly pressed with the hand to allow it to permeate. was repeated to apply the sample or placebo. The condition of the corners of the eyes on the other half, where nothing was applied, was used as a baseline, and the conditions of wrinkles on both corners of the eyes were measured.

(result)
1. Visual wrinkle analysis Table 2 is a table showing the results of visual wrinkle analysis by a skin condition judgment expert, and FIG. 2 shows the results of the visual wrinkle analysis by a skin condition judgment expert in the evaluation test. is a graph showing
As shown in Figure 2 and Table 2, the visual wrinkle reduction rate after 4 weeks of treatment with the multi-purpose serum of the present invention was 3.17% compared to baseline, with a visual reduction of 3.17% on the placebo side. The rate was 0.87%. The visual wrinkle score was significantly (P value <0.05) decreased by using the multi-purpose serum of the present invention compared to the placebo side.

2. Photographic Analysis of Wrinkles Table 3 is a table showing the results of the photographic wrinkle analysis, and FIG. 3 is a graph showing the results of the photographic wrinkle analysis in the evaluation test.
As shown in Table 3, the photographic wrinkle reduction after 4 weeks of treatment with the multi-purpose serum of the present invention was 2.69% compared to baseline, and the photographic reduction on the placebo side was 0.69%. 87%. Photographic wrinkle scores were significantly (P-value < 0.05) decreased by using the multi-purpose serum of the present invention compared to the placebo side.

3. Analysis of wrinkle parameters Table 4 shows a comparison of the results of wrinkle parameter analysis.

As shown in Table 4, the reduction in "mean depth of wrinkles" after 4 weeks of treatment with the multi-purpose serum of the present invention was 5.37%, and the reduction in "mean maximum wrinkle depth" was 6.49%, the reduction in the "wrinkle total volume" was 5.61%, and the reduction in the "Ra" parameter, which indicates the arithmetic mean roughness of the skin in the height direction, was 5.53%. . Compared to the non-treated side, the serum-treated side according to the present invention has significantly higher "average wrinkle depth", "maximum average wrinkle depth", "total wrinkle volume", and "Ra" parameters. (P value <0.05).

4. Questionnaire Table 5 is a table showing the analysis results of the questionnaire regarding the skin condition of the subjects after the end of the 4-week test period. According to the questionnaire, 76 to 81% of the respondents gave positive answers regarding improvement in skin moisture, texture, and overall skin condition. According to a questionnaire about the feeling of use, about 67 to 71% of the respondents gave positive answers regarding "spread", "adherence", and "satisfaction".

5. Safety evaluation No skin disorders were observed in 21 subjects during the test period.
<Conclusion>
The multi-purpose serum of the present invention is believed to have anti-wrinkle effects on human skin.

Although preferred embodiments of the present invention have been described above, the present invention is not limited to the above embodiments, and includes all modifications within the technical scope to which the present invention belongs.

Claims (1)

a basic active ingredient containing one or both of a vitamin C derivative and licorice-derived dipotassium glycyrrhizinate;
A moisturizing agent containing one or both of maltose/sucrose condensate and sodium DL-pyrrolidonecarboxylate;
a functional material containing a whitening/antioxidant agent derived from cherry blossom extract and a collagen production promoter derived from rice extract;
plant extracts and
Certified organic farming ingredients,
including vanadium-containing natural water that springs up in the mountains,
The vitamin C derivative is one or more selected from magnesium ascorbyl phosphate, sodium ascorbyl phosphate, 3-O-ethylascorbic acid, and ascorbyl glucoside,
The cherry blossom extract is an extract containing at least one of flower buds immediately before flowering, cherry leaves, or cherry petals, polyphenols with suppressed polyphenol oxidase activity and suppressed air oxidation,
The plant-derived extract is one or more selected from perilla extract, noni fruit juice, Japanese apricot fruit juice extract, Japanese ginger extract, peony extract, chimp extract, hikiokoshi extract, saxifrage extract, mugwort extract, tea extract, yokuinin extract, and fennel extract. ,
The organic firming material is one or more selected from aloe powder, wild rose extract, hawthorn extract, yarrow extract, sage extract, thyme extract, lavender extract, and rosemary extract,
The multi-purpose beauty essence is an external preparation which protects the skin from extrinsic rough skin, maintains moist and healthy skin, imparts firmness to the skin, and exhibits wrinkle-preventing and whitening effects.

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