JP2008133198A5 - - Google Patents
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- Publication number
- JP2008133198A5 JP2008133198A5 JP2006318379A JP2006318379A JP2008133198A5 JP 2008133198 A5 JP2008133198 A5 JP 2008133198A5 JP 2006318379 A JP2006318379 A JP 2006318379A JP 2006318379 A JP2006318379 A JP 2006318379A JP 2008133198 A5 JP2008133198 A5 JP 2008133198A5
- Authority
- JP
- Japan
- Prior art keywords
- general formula
- carnitine
- halo
- hydroxybutyronitrile
- nitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 6
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims 3
- -1 L-carnitine nitrile halide Chemical class 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000005270 trialkylamine group Chemical group 0.000 claims 2
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 claims 1
- 108010017796 epoxidase Proteins 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000003944 halohydrins Chemical class 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002560 nitrile group Chemical group 0.000 claims 1
- 150000002825 nitriles Chemical class 0.000 claims 1
- 238000005580 one pot reaction Methods 0.000 claims 1
- 0 C*CC(C[N+])O Chemical compound C*CC(C[N+])O 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006318379A JP2008133198A (ja) | 2006-11-27 | 2006-11-27 | Ｌ−カルニチンの製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006318379A JP2008133198A (ja) | 2006-11-27 | 2006-11-27 | Ｌ−カルニチンの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008133198A JP2008133198A (ja) | 2008-06-12 |
| JP2008133198A5 true JP2008133198A5 (https=) | 2010-10-21 |
Family
ID=39558301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006318379A Pending JP2008133198A (ja) | 2006-11-27 | 2006-11-27 | Ｌ−カルニチンの製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2008133198A (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102020575A (zh) * | 2010-12-09 | 2011-04-20 | 浙江工业大学 | 一种左旋肉碱的合成方法 |
| CN105481709A (zh) * | 2015-08-19 | 2016-04-13 | 广西壮族自治区化工研究院 | 一种左旋肉碱粗品的纯化除盐方法 |
| CN115477594A (zh) * | 2022-10-19 | 2022-12-16 | 山东阳谷华泰化工股份有限公司 | 一种l-卡内腈的连续化制备方法 |
| US20240217920A1 (en) * | 2022-12-28 | 2024-07-04 | Hubei Xujie Pharmaceutical Co., Ltd. | Process for producing l-carnitine |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
| JPS62212352A (ja) * | 1986-03-11 | 1987-09-18 | Kanegafuchi Chem Ind Co Ltd | カルニチン中間体の製造方法 |
| JPH0227995A (ja) * | 1988-07-15 | 1990-01-30 | Earth Chem Corp Ltd | ｌ‐カルニチンクロライドの製造法 |
| JP2840722B2 (ja) * | 1989-07-20 | 1998-12-24 | 日東化学工業株式会社 | ４‐ハロ‐３‐ヒドロキシブチロニトリルの製造法 |
| JP3073037B2 (ja) * | 1991-03-04 | 2000-08-07 | 三菱レイヨン株式会社 | ハロヒドリンエポキシダ−ゼ遺伝子を有する組換え体プラスミドおよび該プラスミドにより形質転換された微生物 |
| JP3168202B2 (ja) * | 1992-02-10 | 2001-05-21 | 三菱レイヨン株式会社 | （ｒ）−（−）−４−ハロ−３−ヒドロキシブチロニトリルの製造法 |
| JP3105986B2 (ja) * | 1992-02-10 | 2000-11-06 | 三菱レイヨン株式会社 | 光学活性ハロヒドリンの製造法 |
| JP4785120B2 (ja) * | 2005-08-18 | 2011-10-05 | 三菱レイヨン株式会社 | ハロヒドリンエポキシダーゼ活性を有するロドコッカス属細菌の形質転換体 |
| JP5001725B2 (ja) * | 2006-06-14 | 2012-08-15 | 三菱レイヨン株式会社 | ４−ハロ−３−ヒドロキシブチロニトリルの製造方法 |
| KR101097006B1 (ko) * | 2006-11-09 | 2011-12-20 | 미츠비시 레이온 가부시키가이샤 | 베타인의 제조 방법 |
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2006
- 2006-11-27 JP JP2006318379A patent/JP2008133198A/ja active Pending