|
US8048917B2
(en)
|
2005-04-06 |
2011-11-01 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
|
US7186855B2
(en)
|
2001-06-11 |
2007-03-06 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
|
US7025745B2
(en)
*
|
2002-10-07 |
2006-04-11 |
Advanced Cardiovascular Systems, Inc. |
Method of making a catheter balloon using a tapered mandrel
|
|
US7662987B2
(en)
*
|
2003-07-15 |
2010-02-16 |
Xenoport, Inc. |
Methods for synthesis of acyloxyalkyl compounds
|
|
BRPI0413756A
(pt)
|
2003-08-20 |
2006-10-31 |
Xenoport Inc |
composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica
|
|
KR20060119971A
(ko)
*
|
2003-09-11 |
2006-11-24 |
제노포트 인코포레이티드 |
Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
|
|
SG147437A1
(en)
*
|
2003-10-14 |
2008-11-28 |
Xenoport Inc |
Crystalline form of gamma-aminobutyric acid analog
|
|
CN102702065A
(zh)
|
2003-12-30 |
2012-10-03 |
什诺波特有限公司 |
酰氧基烃基氨基甲酸酯前药及其中间体的合成
|
|
JP2008517930A
(ja)
*
|
2004-10-21 |
2008-05-29 |
トランス テック ファーマ，インコーポレイテッド |
ＧａｌＲ１のアゴニストとしてのビススルホンアミド化合物、組成物、及び使用法
|
|
US7494985B2
(en)
|
2004-11-03 |
2009-02-24 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
|
|
MX2007005306A
(es)
|
2004-11-04 |
2007-06-11 |
Xenoport Inc |
Formas de dosis oral de liberacion sostenida de la prodroga gabapentina.
|
|
US7351740B2
(en)
|
2005-06-20 |
2008-04-01 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
|
|
WO2007085933A2
(en)
*
|
2006-01-25 |
2007-08-02 |
Glenmark Pharmaceuticals Limited |
Process for the preparation of n-[1-(s)-ethoxycarbonyl-1-butyl]-(s)-alanine-dmt complex and its use in the preparation of perindopril
|
|
WO2008013860A2
(en)
*
|
2006-07-28 |
2008-01-31 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of alpha-amino acids, methods of synthesis and use
|
|
US7585996B2
(en)
|
2006-09-15 |
2009-09-08 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
|
TWI369982B
(en)
*
|
2007-01-11 |
2012-08-11 |
Xenoport Inc |
Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment
|
|
US20090118365A1
(en)
*
|
2007-11-06 |
2009-05-07 |
Xenoport, Inc |
Use of Prodrugs of GABA B Agonists for Treating Neuropathic and Musculoskeletal Pain
|
|
ES2601852T3
(es)
*
|
2008-01-25 |
2017-02-16 |
Xenoport, Inc. |
Forma cristalina de sales de calcio de ácidos (3S)-aminometil-5-metil-hexanoicos y métodos de uso
|
|
EP2250148B1
(en)
|
2008-01-25 |
2016-08-17 |
XenoPort, Inc. |
Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
|
|
US7868043B2
(en)
|
2008-01-25 |
2011-01-11 |
Xenoport, Inc. |
Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
|
|
US20100137442A2
(en)
*
|
2008-02-01 |
2010-06-03 |
Xenoport, Inc. |
Sustained Release Particulate Oral Dosage Forms of (R)-Baclofen and Methods of Treatment
|
|
WO2009096985A1
(en)
*
|
2008-02-01 |
2009-08-06 |
Xenoport, Inc. |
Sustained release particulate oral dosage forms of (r)-baclofen prodrugs and methods of treatment
|
|
SG157299A1
(en)
|
2008-05-09 |
2009-12-29 |
Agency Science Tech & Res |
Diagnosis and treatment of kawasaki disease
|
|
US20090318728A1
(en)
*
|
2008-06-24 |
2009-12-24 |
Teva Pharmaceutical Industries Ltd. |
Processes for preparing prodrugs of gabapentin and intermediates thereof
|
|
WO2010003046A2
(en)
*
|
2008-07-02 |
2010-01-07 |
Teva Pharmaceutical Industries Ltd. |
Gabapentin enacarbil salts and processes for their preparation
|
|
US7989641B2
(en)
|
2008-08-07 |
2011-08-02 |
Xenoport, Inc. |
Methods of synthesizing N-hydroxysuccinimidyl carbonates
|
|
US8299291B2
(en)
*
|
2008-08-07 |
2012-10-30 |
Xenoport, Inc. |
Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
|
|
US8283487B2
(en)
*
|
2008-11-26 |
2012-10-09 |
Teva Pharmaceutical Industries Ltd. |
Processes for the preparation and purification of gabapentin enacarbil
|
|
US20100160666A1
(en)
*
|
2008-12-23 |
2010-06-24 |
Teva Pharmaceutical Industries Ltd. |
Preparation of gabapentin enacarbil intermediate
|
|
KR20110117216A
(ko)
*
|
2009-03-03 |
2011-10-26 |
제노포트 인코포레이티드 |
Ｒ-바클로펜 전구약물의 서방형 경구 투약 형태
|
|
JP5580345B2
(ja)
|
2009-03-06 |
2014-08-27 |
ゼノポート，インコーポレイティド |
高充填量のガバペンチンプロドラッグを有する経口剤形
|
|
EP2419401A2
(en)
*
|
2009-04-17 |
2012-02-22 |
XenoPort, Inc. |
GAMMA-AMINO-BUTYRIC ACID DERIVATIVES AS GABAb RECEPTOR LIGANDS
|
|
WO2011012723A1
(en)
|
2009-07-31 |
2011-02-03 |
Ascendis Pharma As |
Injectable sustained release compositions comprising a pramipexole prodrug
|
|
WO2011012721A1
(en)
|
2009-07-31 |
2011-02-03 |
Ascendis Pharma As |
Carrier linked pramipexole prodrugs
|
|
WO2011028234A1
(en)
*
|
2009-09-04 |
2011-03-10 |
Xenoport, Inc. |
Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
|
|
US20110130454A1
(en)
*
|
2009-11-24 |
2011-06-02 |
Xenoport, Inc. |
Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof
|
|
US20110124705A1
(en)
*
|
2009-11-24 |
2011-05-26 |
Xenoport, Inc. |
Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof
|
|
WO2011091164A1
(en)
|
2010-01-22 |
2011-07-28 |
Xenoport, Inc. |
Oral dosage forms having a high loading of a tranexamic acid prodrug
|
|
WO2011109403A1
(en)
|
2010-03-01 |
2011-09-09 |
Xenoport, Inc. |
Use of (3r)-4-{[(1s)-2-methyl-1- (2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl) butanoic acid for treating urinary incontinence
|
|
EP2937334B1
(en)
*
|
2010-03-10 |
2017-04-19 |
Promentis Pharmaceuticals, Inc. |
Propionic acids, propionic acid esters, and related compounds
|
|
EP2548871B1
(en)
|
2010-03-18 |
2017-07-19 |
Daiichi Sankyo Company, Limited |
Cycloalkyl-substituted imidazole derivative
|
|
UA113165C2
(xx)
|
2011-03-01 |
2016-12-26 |
|
Застосування комбінації баклофену і акампросату для лікування неврологічних захворювань та композиція, яка містить баклофен і акампросат
|
|
EP2705842A1
(en)
|
2012-09-05 |
2014-03-12 |
Pharnext |
Therapeutic approaches for treating parkinson's disease
|
|
KR101937782B1
(ko)
|
2011-03-01 |
2019-01-11 |
파넥스트 |
바클로펜 및 아캄프로세이트에 기초한 신경 장애의 치료
|
|
US9248111B2
(en)
|
2011-03-01 |
2016-02-02 |
Pharnext |
Therapeutic approaches for treating parkinson's disease
|
|
US8580850B2
(en)
|
2011-08-11 |
2013-11-12 |
Xenoport, Inc. |
Anhydrous and hemihydrate crystalline forms of an (R)-baclofen prodrug, methods of synthesis and methods of use
|
|
WO2013026777A1
(en)
*
|
2011-08-24 |
2013-02-28 |
Solvay Sa |
Fluoroalkyl s-(fluoro)alkyl thiocarbonates, a method for the preparation of fluoroalkyl s-(fluoro)alkyl thiocarbonates, and their use
|
|
NZ704280A
(en)
|
2012-07-18 |
2017-06-30 |
Pharnext |
Baclofen and acamprosate based therapy of macular degeneration disorders
|
|
EP2705843A1
(en)
|
2012-09-05 |
2014-03-12 |
Pharnext |
Therapeutic approaches for treating epilepsy and related disorders through reduction of epileptogenesis
|
|
EP2705841A1
(en)
|
2012-09-05 |
2014-03-12 |
Pharnext |
Combinations of nootropic agents for treating cognitive dysfunctions
|
|
EP2961730A2
(en)
|
2013-02-26 |
2016-01-06 |
XenoPort, Inc. |
Method of making 1-(acyloxy)-alkyl carbamate compounds
|
|
RS58991B1
(sr)
|
2013-11-05 |
2019-08-30 |
Astrazeneca Ab |
Prolekovi nmda antagonista
|
|
BR112016017993A2
(pt)
|
2014-02-03 |
2017-08-08 |
Quadriga Biosciences Inc |
Gama-aminoácidos beta-substituídos e análogos como agentes quimioterapêuticos
|
|
WO2015117147A1
(en)
|
2014-02-03 |
2015-08-06 |
Quadriga Biosciences, Inc. |
Beta-substituted beta-amino acids and analogs as chemotherapeutic agents
|
|
MX2016010409A
(es)
|
2014-02-11 |
2016-11-30 |
Pharnext |
Combinacion de baclofeno, acamprosato y trigliceridos de cadena media para el tratamiento de trastornos neurologicos.
|
|
WO2016061437A1
(en)
*
|
2014-10-17 |
2016-04-21 |
The Board Of Trustees Of The University Of Illinois |
Scalable synthesis of reduced toxicity derivative of amphotericin b
|
|
US10308612B2
(en)
|
2015-06-26 |
2019-06-04 |
Daiichi Sankyo Company, Limited |
Method for producing 1-(acyloxy)alkyl carbamate derivative
|
|
KR20180035894A
(ko)
|
2015-08-03 |
2018-04-06 |
콰드리가 바이오사이언시스 인코포레이티드 |
화학치료제로서의 베타-치환된 베타-아미노산 및 유사체 및 이들의 용도
|
|
EP3339291A1
(en)
|
2016-12-22 |
2018-06-27 |
Vita Api |
Proteasome inhibiting ss-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders
|
|
CN111050761A
(zh)
|
2017-04-24 |
2020-04-21 |
法奈克斯公司 |
阿尔茨海默病的基于idalopirdine的组合治疗
|
|
CN108976147B
(zh)
*
|
2017-05-31 |
2021-02-12 |
首都医科大学 |
氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用
|
|
EP3746062A1
(en)
|
2018-01-29 |
2020-12-09 |
Pharnext |
Baclofen and acamprosate based therapy of alzheimer's disease in patients having lost responsiveness to acetylcholinesterase inhibitor therapy
|
|
AU2022287974A1
(en)
*
|
2021-06-09 |
2024-01-04 |
Atai Therapeutics, Inc. |
Novel prodrugs and conjugates of dimethyltryptamine
|