JP2008133198A - L−カルニチンの製造方法 - Google Patents

L−カルニチンの製造方法 Download PDF

Info

Publication number
JP2008133198A
JP2008133198A JP2006318379A JP2006318379A JP2008133198A JP 2008133198 A JP2008133198 A JP 2008133198A JP 2006318379 A JP2006318379 A JP 2006318379A JP 2006318379 A JP2006318379 A JP 2006318379A JP 2008133198 A JP2008133198 A JP 2008133198A
Authority
JP
Japan
Prior art keywords
carnitine
reaction
halo
hydroxybutyronitrile
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006318379A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008133198A5 (https=
Inventor
Kosuke Oishi
康介 大石
Eiji Sato
栄治 佐藤
Hiroyuki Mori
浩幸 森
Yasuhiro Ninomiya
康裕 二宮
Akira Yoshioka
彰 吉岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Rayon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Rayon Co Ltd filed Critical Mitsubishi Rayon Co Ltd
Priority to JP2006318379A priority Critical patent/JP2008133198A/ja
Publication of JP2008133198A publication Critical patent/JP2008133198A/ja
Publication of JP2008133198A5 publication Critical patent/JP2008133198A5/ja
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2006318379A 2006-11-27 2006-11-27 L−カルニチンの製造方法 Pending JP2008133198A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2006318379A JP2008133198A (ja) 2006-11-27 2006-11-27 L−カルニチンの製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006318379A JP2008133198A (ja) 2006-11-27 2006-11-27 L−カルニチンの製造方法

Publications (2)

Publication Number Publication Date
JP2008133198A true JP2008133198A (ja) 2008-06-12
JP2008133198A5 JP2008133198A5 (https=) 2010-10-21

Family

ID=39558301

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006318379A Pending JP2008133198A (ja) 2006-11-27 2006-11-27 L−カルニチンの製造方法

Country Status (1)

Country Link
JP (1) JP2008133198A (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102020575A (zh) * 2010-12-09 2011-04-20 浙江工业大学 一种左旋肉碱的合成方法
CN105481709A (zh) * 2015-08-19 2016-04-13 广西壮族自治区化工研究院 一种左旋肉碱粗品的纯化除盐方法
CN115477594A (zh) * 2022-10-19 2022-12-16 山东阳谷华泰化工股份有限公司 一种l-卡内腈的连续化制备方法
WO2024145205A1 (en) * 2022-12-28 2024-07-04 Carnitech Llc An improved process for producing l-carnitine

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165352A (en) * 1981-03-18 1982-10-12 Anic Spa Manufacture of l-carnitine
JPS62212352A (ja) * 1986-03-11 1987-09-18 Kanegafuchi Chem Ind Co Ltd カルニチン中間体の製造方法
JPH0227995A (ja) * 1988-07-15 1990-01-30 Earth Chem Corp Ltd l‐カルニチンクロライドの製造法
JPH0353889A (ja) * 1989-07-20 1991-03-07 Nitto Chem Ind Co Ltd 4‐ハロ‐3‐ヒドロキシブチロニトリルの製造法
JPH04278089A (ja) * 1991-03-04 1992-10-02 Nitto Chem Ind Co Ltd ハロヒドリンエポキシダ−ゼ遺伝子を有する組換え体プラ          スミドおよび該プラスミドにより形質転換された微生物
JPH05219965A (ja) * 1992-02-10 1993-08-31 Nitto Chem Ind Co Ltd 光学活性ハロヒドリンの製造法
JP2001025397A (ja) * 1992-02-10 2001-01-30 Mitsubishi Rayon Co Ltd (r)−(−)−4−ハロ−3−ヒドロキシブチロニトリルの製造法
JP2007049932A (ja) * 2005-08-18 2007-03-01 Mitsubishi Rayon Co Ltd ハロヒドリンエポキシダーゼ活性を有するロドコッカス属細菌の形質転換体
JP2008017838A (ja) * 2006-06-14 2008-01-31 Mitsubishi Rayon Co Ltd 4−ハロ−3−ヒドロキシブチロニトリルの製造方法
WO2008056827A1 (fr) * 2006-11-09 2008-05-15 Mitsubishi Rayon Co., Ltd. Procédé pour la production d'une bétaïne

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165352A (en) * 1981-03-18 1982-10-12 Anic Spa Manufacture of l-carnitine
JPS62212352A (ja) * 1986-03-11 1987-09-18 Kanegafuchi Chem Ind Co Ltd カルニチン中間体の製造方法
JPH0227995A (ja) * 1988-07-15 1990-01-30 Earth Chem Corp Ltd l‐カルニチンクロライドの製造法
JPH0353889A (ja) * 1989-07-20 1991-03-07 Nitto Chem Ind Co Ltd 4‐ハロ‐3‐ヒドロキシブチロニトリルの製造法
JPH04278089A (ja) * 1991-03-04 1992-10-02 Nitto Chem Ind Co Ltd ハロヒドリンエポキシダ−ゼ遺伝子を有する組換え体プラ          スミドおよび該プラスミドにより形質転換された微生物
JPH05219965A (ja) * 1992-02-10 1993-08-31 Nitto Chem Ind Co Ltd 光学活性ハロヒドリンの製造法
JP2001025397A (ja) * 1992-02-10 2001-01-30 Mitsubishi Rayon Co Ltd (r)−(−)−4−ハロ−3−ヒドロキシブチロニトリルの製造法
JP2007049932A (ja) * 2005-08-18 2007-03-01 Mitsubishi Rayon Co Ltd ハロヒドリンエポキシダーゼ活性を有するロドコッカス属細菌の形質転換体
JP2008017838A (ja) * 2006-06-14 2008-01-31 Mitsubishi Rayon Co Ltd 4−ハロ−3−ヒドロキシブチロニトリルの製造方法
WO2008056827A1 (fr) * 2006-11-09 2008-05-15 Mitsubishi Rayon Co., Ltd. Procédé pour la production d'une bétaïne

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102020575A (zh) * 2010-12-09 2011-04-20 浙江工业大学 一种左旋肉碱的合成方法
CN105481709A (zh) * 2015-08-19 2016-04-13 广西壮族自治区化工研究院 一种左旋肉碱粗品的纯化除盐方法
CN115477594A (zh) * 2022-10-19 2022-12-16 山东阳谷华泰化工股份有限公司 一种l-卡内腈的连续化制备方法
WO2024145205A1 (en) * 2022-12-28 2024-07-04 Carnitech Llc An improved process for producing l-carnitine

Similar Documents

Publication Publication Date Title
CN1056192C (zh) D-泛解酸和d-泛酸的生产
JP5797656B2 (ja) カルバミン酸(r)−1−アリール−2−テトラゾリル−エチルエステルの製造方法
TWI304095B (en) Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
JP2015535003A (ja) プレガバリンの調製方法
JP2015535003A5 (https=)
JP5214249B2 (ja) ベタインの製造方法
CN1381586A (zh) 用于产生有旋光力的化合物的方法
CN113755539A (zh) 一种二氢嘧啶氨基水解酶及其应用
KR101565439B1 (ko) 시타글립틴의 합성을 위한 전구체인 베타아미노산을 포함한 다양한 광학활성 베타아미노산의 효소적 생산 방법
JP2008133198A (ja) L−カルニチンの製造方法
JP5001725B2 (ja) 4−ハロ−3−ヒドロキシブチロニトリルの製造方法
JPWO2012176715A1 (ja) 1−アミノ−2−ビニルシクロプロパンカルボン酸アミドおよびその塩、ならびにその製造方法
US20080311631A1 (en) Biosynthetic Production of 4-Amino 4-Deoxychorismate (Adc) and [3R,4R]-4-Amino-3-Hydroxycyclohexa-1,5-Diene-1-Carboxylic Acid (3,4-Cha)
WO2007097336A1 (ja) (2r,3r)および(2s,3s)-3-フェニルイソセリン誘導体の製造法
JP5001631B2 (ja) 4−ハロ−3−ヒドロキシブチロニトリルの工業的製造方法
WO2025131066A1 (en) An improved process for producing l-carnitine
JP2008067626A (ja) 4−ハロ−3−ヒドロキシブチルアミドの製造方法
JP2013009621A (ja) 光学活性4−ハロ−3−ヒドロキシブチロニトリルの製造方法
CN117363667A (zh) 亚胺还原酶在制备达泊西汀中间体和/或达泊西汀中的用途
JP2011072303A (ja) 4−ハロ−3−ヒドロキシブチルアミドの製造方法
JP2011045361A (ja) 4−ハロ−3−ヒドロキシブチルアミドの製造方法
WO2008009710A1 (en) Process for the production of fluorine containing alpha-hydroxy carboxylic acids
WO2021105742A1 (en) An improved process for the preparation of pregabalin
US20080241896A1 (en) Process for production of optically active hydroxymethyl-substituted phenylalanine
JP2012193141A (ja) カルニチンの製造方法

Legal Events

Date Code Title Description
A521 Written amendment

Effective date: 20091026

Free format text: JAPANESE INTERMEDIATE CODE: A523

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20091026

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100906

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20120214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120329

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120719