JP2007537212A5 - - Google Patents
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- Publication number
- JP2007537212A5 JP2007537212A5 JP2007512277A JP2007512277A JP2007537212A5 JP 2007537212 A5 JP2007537212 A5 JP 2007537212A5 JP 2007512277 A JP2007512277 A JP 2007512277A JP 2007512277 A JP2007512277 A JP 2007512277A JP 2007537212 A5 JP2007537212 A5 JP 2007537212A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- formula
- aryl
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 29
- 125000003118 aryl group Chemical group 0.000 claims 21
- 125000001072 heteroaryl group Chemical group 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 15
- 125000005843 halogen group Chemical group 0.000 claims 14
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 10
- 125000002733 (C1-C6) fluoroalkyl group Chemical group 0.000 claims 10
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 10
- 125000004429 atom Chemical group 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 239000012453 solvate Substances 0.000 claims 6
- 239000002253 acid Substances 0.000 claims 5
- 125000004093 cyano group Chemical group *C#N 0.000 claims 5
- 125000000623 heterocyclic group Chemical group 0.000 claims 5
- 229910052757 nitrogen Inorganic materials 0.000 claims 5
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 5
- 229910052717 sulfur Inorganic materials 0.000 claims 5
- 125000004434 sulfur atom Chemical group 0.000 claims 5
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims 4
- CKDWPUIZGOQOOM-UHFFFAOYSA-N Carbamyl chloride Chemical class NC(Cl)=O CKDWPUIZGOQOOM-UHFFFAOYSA-N 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 125000003709 fluoroalkyl group Chemical group 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 238000006356 dehydrogenation reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000003226 pyrazolyl group Chemical group 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0405055 | 2004-05-11 | ||
| FR0405055A FR2870239B1 (fr) | 2004-05-11 | 2004-05-11 | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
| PCT/FR2005/001154 WO2005121099A1 (fr) | 2004-05-11 | 2005-05-10 | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007537212A JP2007537212A (ja) | 2007-12-20 |
| JP2007537212A5 true JP2007537212A5 (enExample) | 2012-02-02 |
| JP4909889B2 JP4909889B2 (ja) | 2012-04-04 |
Family
ID=34947852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512277A Expired - Fee Related JP4909889B2 (ja) | 2004-05-11 | 2005-05-10 | ２ｈ−又は３ｈ−ベンゾ［ｅ］インダゾール１−イルカルバメート誘導体、これらの調製及び治療的使用 |
Country Status (32)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2870239B1 (fr) | 2004-05-11 | 2006-06-16 | Sanofi Synthelabo | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
| WO2007088528A1 (en) * | 2006-02-03 | 2007-08-09 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Microtubule targeting agents |
| CL2008000793A1 (es) * | 2007-03-23 | 2008-05-30 | Xenon Pharmaceuticals Inc | Compuestos derivados de dihidroindazol; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno del hierro. |
| PL3022185T3 (pl) * | 2013-07-15 | 2018-02-28 | Basf Se | Związki szkodnikobójcze |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0607076A1 (fr) * | 1993-01-15 | 1994-07-20 | Synthelabo | Dérivés de 9h-imidazo 1,2-a benzimidazole-3-acétamide à activité GABA |
| TW403738B (en) * | 1994-08-12 | 2000-09-01 | Hoffmann La Roche | Tricyclic pyrazole derivatives |
| FR2741073B1 (fr) * | 1995-11-09 | 1997-12-12 | Synthelabo | Derives de 4,5-dihydroimidazo(1,2-a)pyrrolo(1,2,3-cd) benzimidazole, leur preparation et leur application en therapeutique |
| AR006520A1 (es) * | 1996-03-20 | 1999-09-08 | Astra Pharma Prod | Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion. |
| ZA9810490B (en) * | 1997-12-03 | 1999-05-20 | Dainippon Pharmaceutical Co | 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor |
| WO1999058117A1 (fr) * | 1998-05-13 | 1999-11-18 | Sanofi-Synthelabo | Utilisation de composes reduisant l'apoptose |
| BR0113697A (pt) * | 2000-09-06 | 2003-07-22 | Neurogen Corp | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou sal, embalagem e métodos para, para alterar a atividade transdutora de sinal dos receptores de gabaa, para tratar ansiedade, depressão, um distúrbio do sono, ou demência de alzheimer, para demonstrar a presença dos receptores de gabaa em células ou amostras de tecido e para preparar um composto |
| AU9022901A (en) * | 2000-09-18 | 2002-03-26 | Eisai Co Ltd | Pyridazinones and triazinones and medicinal use thereof |
| FR2870239B1 (fr) * | 2004-05-11 | 2006-06-16 | Sanofi Synthelabo | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
-
2004
- 2004-05-11 FR FR0405055A patent/FR2870239B1/fr not_active Expired - Fee Related
-
2005
- 2005-05-09 AR ARP050101865A patent/AR049090A1/es unknown
- 2005-05-10 NZ NZ549330A patent/NZ549330A/en not_active IP Right Cessation
- 2005-05-10 RS RSP-2009/0012A patent/RS50724B/sr unknown
- 2005-05-10 PT PT05770962T patent/PT1747201E/pt unknown
- 2005-05-10 HR HR20090012T patent/HRP20090012T3/xx unknown
- 2005-05-10 DK DK05770962T patent/DK1747201T3/da active
- 2005-05-10 AU AU2005251982A patent/AU2005251982B2/en not_active Ceased
- 2005-05-10 BR BRPI0508563-2A patent/BRPI0508563A/pt not_active IP Right Cessation
- 2005-05-10 DE DE602005010418T patent/DE602005010418D1/de not_active Expired - Lifetime
- 2005-05-10 TW TW094114981A patent/TWI349004B/zh not_active IP Right Cessation
- 2005-05-10 CN CN200580007686A patent/CN100577648C/zh not_active Expired - Fee Related
- 2005-05-10 ES ES05770962T patent/ES2315898T3/es not_active Expired - Lifetime
- 2005-05-10 WO PCT/FR2005/001154 patent/WO2005121099A1/fr not_active Ceased
- 2005-05-10 JP JP2007512277A patent/JP4909889B2/ja not_active Expired - Fee Related
- 2005-05-10 PL PL05770962T patent/PL1747201T3/pl unknown
- 2005-05-10 RU RU2006132325/04A patent/RU2379293C2/ru not_active IP Right Cessation
- 2005-05-10 AT AT05770962T patent/ATE411295T1/de active
- 2005-05-10 CA CA2557942A patent/CA2557942C/fr not_active Expired - Fee Related
- 2005-05-10 KR KR1020067018339A patent/KR101165483B1/ko not_active Expired - Fee Related
- 2005-05-10 EP EP05770962A patent/EP1747201B8/fr not_active Expired - Lifetime
- 2005-05-10 SI SI200530546T patent/SI1747201T1/sl unknown
- 2005-10-05 UA UAA200609699A patent/UA85866C2/uk unknown
-
2006
- 2006-08-15 TN TNP2006000258A patent/TNSN06258A1/fr unknown
- 2006-08-22 IL IL177632A patent/IL177632A/en not_active IP Right Cessation
- 2006-08-24 CR CR8570A patent/CR8570A/es unknown
- 2006-08-29 MA MA29294A patent/MA28372A1/fr unknown
- 2006-08-29 EC EC2006006810A patent/ECSP066810A/es unknown
- 2006-08-30 ZA ZA2006/07244A patent/ZA200607244B/en unknown
- 2006-09-11 NO NO20064073A patent/NO20064073L/no not_active Application Discontinuation
- 2006-10-13 US US11/549,293 patent/US7501449B2/en not_active Expired - Fee Related
-
2009
- 2009-01-14 CY CY20091100042T patent/CY1108710T1/el unknown
- 2009-01-27 US US12/360,535 patent/US8114899B2/en not_active Expired - Fee Related
-
2012
- 2012-01-11 US US13/348,241 patent/US8258168B2/en not_active Expired - Fee Related
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