RU2379293C2 - Производные 2н- или 3н-бензо[е]индазол-1-ил-карбамата, их получение и их применение в терапии - Google Patents
Производные 2н- или 3н-бензо[е]индазол-1-ил-карбамата, их получение и их применение в терапии Download PDFInfo
- Publication number
- RU2379293C2 RU2379293C2 RU2006132325/04A RU2006132325A RU2379293C2 RU 2379293 C2 RU2379293 C2 RU 2379293C2 RU 2006132325/04 A RU2006132325/04 A RU 2006132325/04A RU 2006132325 A RU2006132325 A RU 2006132325A RU 2379293 C2 RU2379293 C2 RU 2379293C2
- Authority
- RU
- Russia
- Prior art keywords
- benzo
- indazol
- dihydro
- chloro
- diethylcarbamate
- Prior art date
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- 238000002560 therapeutic procedure Methods 0.000 title description 2
- LUAUVMLFUHKNBQ-UHFFFAOYSA-N 3H-benzo[e]indazol-1-ylcarbamic acid Chemical class C1=CC=C2C(=C1)C=CC3=C2C(=NN3)NC(=O)O LUAUVMLFUHKNBQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract description 89
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- OMMMSPJFGQYDKP-UHFFFAOYSA-N (2-ethyl-4,5-dihydrobenzo[e]indazol-1-yl) n-methyl-n-phenylcarbamate Chemical compound CCN1N=C2CCC3=CC=CC=C3C2=C1OC(=O)N(C)C1=CC=CC=C1 OMMMSPJFGQYDKP-UHFFFAOYSA-N 0.000 claims 1
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- NWVAMTFNBGKGEV-UHFFFAOYSA-N [2-(3-chloro-4-methylphenyl)-4,5-dihydrobenzo[e]indazol-1-yl] n,n-diethylcarbamate Chemical compound CCN(CC)C(=O)OC1=C(C2=CC=CC=C2CC2)C2=NN1C1=CC=C(C)C(Cl)=C1 NWVAMTFNBGKGEV-UHFFFAOYSA-N 0.000 claims 1
- UXUKSAAQEPARHS-UHFFFAOYSA-N [2-(3-chlorophenyl)-4,5-dihydrobenzo[e]indazol-1-yl] n,n-diethylcarbamate Chemical compound CCN(CC)C(=O)OC1=C(C2=CC=CC=C2CC2)C2=NN1C1=CC=CC(Cl)=C1 UXUKSAAQEPARHS-UHFFFAOYSA-N 0.000 claims 1
- HOCATUICAUVZCS-UHFFFAOYSA-N [2-(4-fluorophenyl)benzo[e]indazol-1-yl] n,n-diethylcarbamate Chemical compound N1=C2C=CC3=CC=CC=C3C2=C(OC(=O)N(CC)CC)N1C1=CC=C(F)C=C1 HOCATUICAUVZCS-UHFFFAOYSA-N 0.000 claims 1
- DWLVWMUCHSLGSU-UHFFFAOYSA-N dimethylcarbamic acid Chemical compound CN(C)C(O)=O DWLVWMUCHSLGSU-UHFFFAOYSA-N 0.000 claims 1
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- 230000003993 interaction Effects 0.000 claims 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0405055 | 2004-05-11 | ||
| FR0405055A FR2870239B1 (fr) | 2004-05-11 | 2004-05-11 | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006132325A RU2006132325A (ru) | 2008-03-20 |
| RU2379293C2 true RU2379293C2 (ru) | 2010-01-20 |
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| RU2006132325/04A RU2379293C2 (ru) | 2004-05-11 | 2005-05-10 | Производные 2н- или 3н-бензо[е]индазол-1-ил-карбамата, их получение и их применение в терапии |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2870239B1 (fr) * | 2004-05-11 | 2006-06-16 | Sanofi Synthelabo | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
| WO2007088528A1 (en) * | 2006-02-03 | 2007-08-09 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Microtubule targeting agents |
| CL2008000793A1 (es) * | 2007-03-23 | 2008-05-30 | Xenon Pharmaceuticals Inc | Compuestos derivados de dihidroindazol; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno del hierro. |
| MX2016000669A (es) * | 2013-07-15 | 2016-11-11 | Basf Se | Compuestos plaguicidas. |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0607076A1 (fr) * | 1993-01-15 | 1994-07-20 | Synthelabo | Dérivés de 9h-imidazo 1,2-a benzimidazole-3-acétamide à activité GABA |
| RU2152388C1 (ru) * | 1994-08-12 | 2000-07-10 | Ф.Хоффманн-Ля Рош Аг | Трициклические производные пиразола |
| WO2002022587A1 (en) * | 2000-09-18 | 2002-03-21 | Eisai Co., Ltd. | Pyridazinones and triazinones and medicinal use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2741073B1 (fr) * | 1995-11-09 | 1997-12-12 | Synthelabo | Derives de 4,5-dihydroimidazo(1,2-a)pyrrolo(1,2,3-cd) benzimidazole, leur preparation et leur application en therapeutique |
| ID16283A (id) * | 1996-03-20 | 1997-09-18 | Astra Pharma Prod | Senyawa yang berguna dibidang farmasi |
| ZA9810490B (en) * | 1997-12-03 | 1999-05-20 | Dainippon Pharmaceutical Co | 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor |
| WO1999058117A1 (fr) * | 1998-05-13 | 1999-11-18 | Sanofi-Synthelabo | Utilisation de composes reduisant l'apoptose |
| MXPA03001945A (es) * | 2000-09-06 | 2003-09-10 | Neurogen Corp | Tetrahidroindazoles sustituidos con arilo y su uso como ligandos para el receptor gaba-a. |
| FR2870239B1 (fr) * | 2004-05-11 | 2006-06-16 | Sanofi Synthelabo | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0607076A1 (fr) * | 1993-01-15 | 1994-07-20 | Synthelabo | Dérivés de 9h-imidazo 1,2-a benzimidazole-3-acétamide à activité GABA |
| RU2152388C1 (ru) * | 1994-08-12 | 2000-07-10 | Ф.Хоффманн-Ля Рош Аг | Трициклические производные пиразола |
| WO2002022587A1 (en) * | 2000-09-18 | 2002-03-21 | Eisai Co., Ltd. | Pyridazinones and triazinones and medicinal use thereof |
Non-Patent Citations (1)
| Title |
|---|
| Anne Olivier et al. Bioorganic & Medicinal Chemistry Letters. Vol.7, no. 17, pp.2277-2282, 1997. Yoshihiko Kitaura et al. J. Med. Chem. 1982, 25, 337-339. * |
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