JP2007537189A5 - - Google Patents

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Publication number
JP2007537189A5
JP2007537189A5 JP2007512069A JP2007512069A JP2007537189A5 JP 2007537189 A5 JP2007537189 A5 JP 2007537189A5 JP 2007512069 A JP2007512069 A JP 2007512069A JP 2007512069 A JP2007512069 A JP 2007512069A JP 2007537189 A5 JP2007537189 A5 JP 2007537189A5
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JP
Japan
Prior art keywords
formula
compound
reaction
perindopril
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007512069A
Other languages
English (en)
Japanese (ja)
Other versions
JP5032983B2 (ja
JP2007537189A (ja
Filing date
Publication date
Priority claimed from SI200400143A external-priority patent/SI21800A/sl
Application filed filed Critical
Publication of JP2007537189A publication Critical patent/JP2007537189A/ja
Publication of JP2007537189A5 publication Critical patent/JP2007537189A5/ja
Application granted granted Critical
Publication of JP5032983B2 publication Critical patent/JP5032983B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007512069A 2004-05-14 2005-05-10 ペリンドプリルまたはおよびその塩の調製のための方法 Expired - Fee Related JP5032983B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SI200400143A SI21800A (sl) 2004-05-14 2004-05-14 Nov postopek sinteze perindoprila
SIP-200400143 2004-05-14
SIP-200400235 2004-08-05
SI200400235A SI21852A (sl) 2004-05-14 2004-08-05 Nov postopek sinteze perindoprila
PCT/EP2005/005048 WO2005113500A1 (en) 2004-05-14 2005-05-10 Process for the preparation of perindopril and salts thereof

Publications (3)

Publication Number Publication Date
JP2007537189A JP2007537189A (ja) 2007-12-20
JP2007537189A5 true JP2007537189A5 (https=) 2012-02-23
JP5032983B2 JP5032983B2 (ja) 2012-09-26

Family

ID=34969318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007512069A Expired - Fee Related JP5032983B2 (ja) 2004-05-14 2005-05-10 ペリンドプリルまたはおよびその塩の調製のための方法

Country Status (17)

Country Link
US (1) US7674814B2 (https=)
EP (1) EP1753720B1 (https=)
JP (1) JP5032983B2 (https=)
AU (1) AU2005245087B2 (https=)
CA (1) CA2566754C (https=)
CY (1) CY1115222T1 (https=)
DK (1) DK1753720T3 (https=)
EA (1) EA011322B1 (https=)
ES (1) ES2466248T3 (https=)
HR (1) HRP20140487T1 (https=)
NO (1) NO337892B1 (https=)
PL (1) PL1753720T3 (https=)
PT (1) PT1753720E (https=)
SI (3) SI21800A (https=)
UA (1) UA83139C2 (https=)
WO (1) WO2005113500A1 (https=)
ZA (1) ZA200609915B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT1729739T (lt) * 2004-03-29 2016-11-10 Les Laboratoires Servier Kietos farmacinės kompozicijos gamybos būdas
US7291745B2 (en) 2005-03-21 2007-11-06 Glenmark Pharmaceuticals Limited Process for the preparation of perindopril
JP2006290825A (ja) * 2005-04-13 2006-10-26 Shiono Chemical Co Ltd アルファ型ペリンドプリルエルブミンの製造法
SI22543A (sl) 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity
PH12018502155B1 (en) 2016-04-20 2024-03-27 Servier Lab Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid

Family Cites Families (41)

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IE52663B1 (en) 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4425355A (en) * 1981-02-17 1984-01-10 Warner-Lambert Company Substituted acyl derivatives of chair form of octahydro-1H-indole-2-carboxylic acids
US4743450A (en) 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
FR2620700B1 (fr) 1987-09-17 1990-06-01 Adir Procede de synthese d'alpha amino acides n alkyles et leurs esters. application a la synthese de carboxyalkyl dipeptides
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
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SI9600169A (en) 1996-05-22 1997-12-31 Krka Tovarna Zdravil Process for preparation of compounds with ace inhibitory effect
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FR2811320B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811319B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
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SI1333026T1 (sl) 2002-01-30 2007-10-31 Servier Lab Postopek priprave perindoprila visoke äśistoäśe in intermediatov uporabnih v sintezi
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FR2838648B1 (fr) 2002-04-18 2004-05-21 Servier Lab Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent
JP4533134B2 (ja) * 2002-06-10 2010-09-01 エラン ファーマ インターナショナル,リミティド ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ
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DK1338591T3 (da) 2003-02-28 2006-01-23 Servier Lab Fremgangsmåde til syntese af (2S,3aS,7aS)-perhydroindol-2-carboxylsyre og estere heraf samt anvendelse heraf ved syntese af perindopril
WO2004075889A1 (en) 2003-02-28 2004-09-10 Lupin Limited Process for preparation of perindopril and salts thereof
ES2231760T3 (es) 2003-03-12 2005-05-16 Les Laboratoires Servier Nuevo procedimiento de sintesis del acido(2s, 3as,7as)perhidroindol-2-carboxilico y de sus esteres, y su aplicacion a la sintesis de perindopril.
ES2256689T3 (es) * 2003-06-30 2006-07-16 Les Laboratoires Servier Nuevo procedimiento de sintesis del perindopril y de sus sales farmaceuticamente aceptables.
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GB2404336A (en) 2003-07-30 2005-02-02 Cipla Ltd Stabilisation of therapeutic agents using a carbonate salt of an amino acid, preferably in the presence of a saccharide, & pharmaceutical compositions thereof
ES2271498T3 (es) * 2003-07-31 2007-04-16 Les Laboratoires Servier Nuevo procedimiento de sintesis de perindopril y de sus sales farmaceuticamente aceptables.
SI1367062T1 (sl) * 2003-07-31 2006-12-31 Servier Lab Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli
DE60329648D1 (de) 2003-09-01 2009-11-26 Servier Lab Neues Verfahren zur Herstellung von Estern des N-((S)-1-Carboxybutyl)-(S)-alanins und seine Verwendung in der Synthese von Perindopril
ATE315046T1 (de) 2003-09-30 2006-02-15 Servier Lab Verfahren zur herstellung von n-((s)-1- (etoxycarbonyl)butyl)-(s)-alanin und verwendung in der synthese von perindopril
SI1403278T1 (en) 2003-09-30 2005-10-31 Les Laboratoires Servier Process for the synthesis of N-((S)-1-(ethoxycarbonyl)butyl)-(S)-alanine and use in the synthese of perindopril
GB2394660A (en) 2003-12-17 2004-05-05 Niche Generics Ltd Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide
LT1729739T (lt) * 2004-03-29 2016-11-10 Les Laboratoires Servier Kietos farmacinės kompozicijos gamybos būdas

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