JP2007534731A - アテローム性動脈硬化症の予防および処置のための医薬組成物 - Google Patents
アテローム性動脈硬化症の予防および処置のための医薬組成物 Download PDFInfo
- Publication number
- JP2007534731A JP2007534731A JP2007510084A JP2007510084A JP2007534731A JP 2007534731 A JP2007534731 A JP 2007534731A JP 2007510084 A JP2007510084 A JP 2007510084A JP 2007510084 A JP2007510084 A JP 2007510084A JP 2007534731 A JP2007534731 A JP 2007534731A
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- JP
- Japan
- Prior art keywords
- arginine
- day
- statin
- atorvastatin
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0404569A FR2869539B1 (fr) | 2004-04-29 | 2004-04-29 | Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose |
| PCT/FR2005/001083 WO2005115371A1 (fr) | 2004-04-29 | 2005-04-29 | Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007534731A true JP2007534731A (ja) | 2007-11-29 |
| JP2007534731A5 JP2007534731A5 (enExample) | 2008-05-22 |
Family
ID=34945560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007510084A Pending JP2007534731A (ja) | 2004-04-29 | 2005-04-29 | アテローム性動脈硬化症の予防および処置のための医薬組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20070219225A1 (enExample) |
| EP (1) | EP1755582B1 (enExample) |
| JP (1) | JP2007534731A (enExample) |
| ES (1) | ES2387890T3 (enExample) |
| FR (1) | FR2869539B1 (enExample) |
| PT (1) | PT1755582E (enExample) |
| WO (1) | WO2005115371A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016065028A (ja) * | 2014-09-26 | 2016-04-28 | 共和薬品工業株式会社 | 医薬組成物 |
| JP2018027987A (ja) * | 2017-11-24 | 2018-02-22 | 共和薬品工業株式会社 | 医薬組成物 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2913885B1 (fr) * | 2007-03-22 | 2012-07-20 | Univ Paris Descartes | Utilisation de la citrulline pour le traitement des pathologies liees a une augmentation de la carbonylation des proteines |
| CN102600260A (zh) * | 2010-12-24 | 2012-07-25 | 漆又毛 | 一种氨基酸和提取物组合物防治老年性痴呆的药物用途 |
| FR2970414B1 (fr) | 2011-01-14 | 2013-03-22 | Univ Paris Descartes | Action preventive de la citrulline sur le developpement spontane des tumeurs |
| FR2987270A1 (fr) * | 2012-02-29 | 2013-08-30 | Agronomique Inst Nat Rech | Produit de combinaison pour le traitement du surpoids et/ou l'amelioration de la silhouette |
| WO2014139469A1 (en) * | 2013-03-15 | 2014-09-18 | Wuhan Qr Science And Technology Development Co. | Ornithine- or aspartate-containing compositions and the uses thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0104041A1 (en) * | 1982-09-15 | 1984-03-28 | Aktiebolaget Hässle | Enzyme inhibitors |
| JPS59130257A (ja) * | 1982-09-15 | 1984-07-26 | アクチェボラゲット・ヘッスレ | ポリペプチド同族体 |
| US4749687A (en) * | 1984-03-12 | 1988-06-07 | Pfizer Inc. | Renin inhibitors containing statine or derivatives thereof |
| JPH01143898A (ja) * | 1987-10-13 | 1989-06-06 | Merck & Co Inc | 新規c末端アミノ酸アミドを有するテトラペプチドレニン阻害剤 |
| JP2001523224A (ja) * | 1997-04-10 | 2001-11-20 | カエセマイアー,ウェイン,エイチ | 血管疾患の治療法及び製剤 |
| US20030114515A1 (en) * | 1997-04-10 | 2003-06-19 | Kaesemeyer Wayne H. | Therapeutic mixture of HMG-COA reductase inhibitors |
| WO2003082816A1 (en) * | 2002-03-28 | 2003-10-09 | Richter Gedeon Vegyészeti Gyár Rt. | New atorvastatin salts and pharmaceutical compositions containing them |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6425881B1 (en) * | 1994-10-05 | 2002-07-30 | Nitrosystems, Inc. | Therapeutic mixture useful in inhibiting lesion formation after vascular injury |
| US6028107A (en) * | 1997-02-27 | 2000-02-22 | Waugh; William Howard | Orthomolecular medical use of L-citrulline for vasoprotection, relaxative smooth muscle tone and cell protection |
| US20030119714A1 (en) * | 2000-12-15 | 2003-06-26 | Naylor Alasdair Mark | Treatment of male sexual dysfunction |
-
2004
- 2004-04-29 FR FR0404569A patent/FR2869539B1/fr not_active Expired - Fee Related
-
2005
- 2005-04-29 PT PT05763719T patent/PT1755582E/pt unknown
- 2005-04-29 US US11/587,426 patent/US20070219225A1/en not_active Abandoned
- 2005-04-29 ES ES05763719T patent/ES2387890T3/es not_active Expired - Lifetime
- 2005-04-29 JP JP2007510084A patent/JP2007534731A/ja active Pending
- 2005-04-29 EP EP05763719A patent/EP1755582B1/fr not_active Expired - Lifetime
- 2005-04-29 WO PCT/FR2005/001083 patent/WO2005115371A1/fr not_active Ceased
-
2008
- 2008-07-14 US US12/172,362 patent/US20080312263A1/en not_active Abandoned
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0104041A1 (en) * | 1982-09-15 | 1984-03-28 | Aktiebolaget Hässle | Enzyme inhibitors |
| JPS59130257A (ja) * | 1982-09-15 | 1984-07-26 | アクチェボラゲット・ヘッスレ | ポリペプチド同族体 |
| US4749687A (en) * | 1984-03-12 | 1988-06-07 | Pfizer Inc. | Renin inhibitors containing statine or derivatives thereof |
| JPH01143898A (ja) * | 1987-10-13 | 1989-06-06 | Merck & Co Inc | 新規c末端アミノ酸アミドを有するテトラペプチドレニン阻害剤 |
| JP2001523224A (ja) * | 1997-04-10 | 2001-11-20 | カエセマイアー,ウェイン,エイチ | 血管疾患の治療法及び製剤 |
| US20030114515A1 (en) * | 1997-04-10 | 2003-06-19 | Kaesemeyer Wayne H. | Therapeutic mixture of HMG-COA reductase inhibitors |
| WO2003082816A1 (en) * | 2002-03-28 | 2003-10-09 | Richter Gedeon Vegyészeti Gyár Rt. | New atorvastatin salts and pharmaceutical compositions containing them |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016065028A (ja) * | 2014-09-26 | 2016-04-28 | 共和薬品工業株式会社 | 医薬組成物 |
| JP2018027987A (ja) * | 2017-11-24 | 2018-02-22 | 共和薬品工業株式会社 | 医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2387890T3 (es) | 2012-10-03 |
| EP1755582A1 (fr) | 2007-02-28 |
| EP1755582B1 (fr) | 2012-06-20 |
| FR2869539B1 (fr) | 2008-08-08 |
| FR2869539A1 (fr) | 2005-11-04 |
| US20080312263A1 (en) | 2008-12-18 |
| WO2005115371A1 (fr) | 2005-12-08 |
| US20070219225A1 (en) | 2007-09-20 |
| PT1755582E (pt) | 2012-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080403 |
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| A621 | Written request for application examination |
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| A131 | Notification of reasons for refusal |
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| A601 | Written request for extension of time |
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| A602 | Written permission of extension of time |
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| A02 | Decision of refusal |
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