FR2869539B1 - Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose - Google Patents

Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose

Info

Publication number
FR2869539B1
FR2869539B1 FR0404569A FR0404569A FR2869539B1 FR 2869539 B1 FR2869539 B1 FR 2869539B1 FR 0404569 A FR0404569 A FR 0404569A FR 0404569 A FR0404569 A FR 0404569A FR 2869539 B1 FR2869539 B1 FR 2869539B1
Authority
FR
France
Prior art keywords
atherosclerosis
prevention
treatment
pharmaceutical compositions
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0404569A
Other languages
English (en)
French (fr)
Other versions
FR2869539A1 (fr
Inventor
Remy Couderc
Carole Rasmusen
Chantal Martin
Viviane Tricottet
Luc Cynober
Christophe Moinard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Université Paris Descartes
Original Assignee
Université Paris Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0404569A priority Critical patent/FR2869539B1/fr
Application filed by Université Paris Descartes filed Critical Université Paris Descartes
Priority to PT05763719T priority patent/PT1755582E/pt
Priority to ES05763719T priority patent/ES2387890T3/es
Priority to US11/587,426 priority patent/US20070219225A1/en
Priority to EP05763719A priority patent/EP1755582B1/fr
Priority to JP2007510084A priority patent/JP2007534731A/ja
Priority to PCT/FR2005/001083 priority patent/WO2005115371A1/fr
Publication of FR2869539A1 publication Critical patent/FR2869539A1/fr
Priority to US12/172,362 priority patent/US20080312263A1/en
Application granted granted Critical
Publication of FR2869539B1 publication Critical patent/FR2869539B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0404569A 2004-04-29 2004-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose Expired - Fee Related FR2869539B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0404569A FR2869539B1 (fr) 2004-04-29 2004-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose
ES05763719T ES2387890T3 (es) 2004-04-29 2005-04-29 Composiciones farmacéuticas para la prevención y el tratamiento de la aterosclerosis
US11/587,426 US20070219225A1 (en) 2004-04-29 2005-04-29 Pharmaceutical Compositions For The Prevention And Treatment Of Atherosclerosis
EP05763719A EP1755582B1 (fr) 2004-04-29 2005-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose
PT05763719T PT1755582E (pt) 2004-04-29 2005-04-29 Composições farmacêuticas para a prevenção e o tratamento da aterosclerose
JP2007510084A JP2007534731A (ja) 2004-04-29 2005-04-29 アテローム性動脈硬化症の予防および処置のための医薬組成物
PCT/FR2005/001083 WO2005115371A1 (fr) 2004-04-29 2005-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose
US12/172,362 US20080312263A1 (en) 2004-04-29 2008-07-14 Pharmaceutical compositions for the prevention and treatment of atherosclerosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0404569A FR2869539B1 (fr) 2004-04-29 2004-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose

Publications (2)

Publication Number Publication Date
FR2869539A1 FR2869539A1 (fr) 2005-11-04
FR2869539B1 true FR2869539B1 (fr) 2008-08-08

Family

ID=34945560

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0404569A Expired - Fee Related FR2869539B1 (fr) 2004-04-29 2004-04-29 Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose

Country Status (7)

Country Link
US (2) US20070219225A1 (enExample)
EP (1) EP1755582B1 (enExample)
JP (1) JP2007534731A (enExample)
ES (1) ES2387890T3 (enExample)
FR (1) FR2869539B1 (enExample)
PT (1) PT1755582E (enExample)
WO (1) WO2005115371A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2913885B1 (fr) * 2007-03-22 2012-07-20 Univ Paris Descartes Utilisation de la citrulline pour le traitement des pathologies liees a une augmentation de la carbonylation des proteines
CN102600260A (zh) * 2010-12-24 2012-07-25 漆又毛 一种氨基酸和提取物组合物防治老年性痴呆的药物用途
FR2970414B1 (fr) 2011-01-14 2013-03-22 Univ Paris Descartes Action preventive de la citrulline sur le developpement spontane des tumeurs
FR2987270A1 (fr) * 2012-02-29 2013-08-30 Agronomique Inst Nat Rech Produit de combinaison pour le traitement du surpoids et/ou l'amelioration de la silhouette
CN105246472B (zh) * 2013-03-15 2018-10-12 武汉朗来科技发展有限公司 含有鸟氨酸和/或门冬氨酸的组合物及其应用
JP6320260B2 (ja) * 2014-09-26 2018-05-09 共和薬品工業株式会社 医薬組成物
JP2018027987A (ja) * 2017-11-24 2018-02-22 共和薬品工業株式会社 医薬組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104041B1 (en) * 1982-09-15 1988-07-27 Aktiebolaget Hässle Enzyme inhibitors
US4650661A (en) * 1982-09-15 1987-03-17 Aktiebolaget Hassle Enzyme inhibitors
DK110285A (da) * 1984-03-12 1985-09-13 Pfizer Polypeptider og polypeptidderivater indeholdende statin eller derivater deraf og farmaceutiske praeparater
EP0312157A3 (en) * 1987-10-13 1990-07-25 Merck & Co. Inc. Tetrapeptide renin inhibitors having a novel c-terminal amino acid
US6425881B1 (en) * 1994-10-05 2002-07-30 Nitrosystems, Inc. Therapeutic mixture useful in inhibiting lesion formation after vascular injury
US5968983A (en) * 1994-10-05 1999-10-19 Nitrosystems, Inc Method and formulation for treating vascular disease
US6028107A (en) * 1997-02-27 2000-02-22 Waugh; William Howard Orthomolecular medical use of L-citrulline for vasoprotection, relaxative smooth muscle tone and cell protection
US20030114515A1 (en) * 1997-04-10 2003-06-19 Kaesemeyer Wayne H. Therapeutic mixture of HMG-COA reductase inhibitors
US20030119714A1 (en) * 2000-12-15 2003-06-26 Naylor Alasdair Mark Treatment of male sexual dysfunction
HUP0201083A2 (hu) * 2002-03-28 2004-06-28 Richter Gedeon Vegyészeti Gyár Rt. Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények

Also Published As

Publication number Publication date
JP2007534731A (ja) 2007-11-29
EP1755582B1 (fr) 2012-06-20
US20070219225A1 (en) 2007-09-20
US20080312263A1 (en) 2008-12-18
EP1755582A1 (fr) 2007-02-28
ES2387890T3 (es) 2012-10-03
FR2869539A1 (fr) 2005-11-04
WO2005115371A1 (fr) 2005-12-08
PT1755582E (pt) 2012-08-17

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Legal Events

Date Code Title Description
CD Change of name or company name
TQ Partial transmission of property
PLFP Fee payment

Year of fee payment: 13

ST Notification of lapse

Effective date: 20171229