JP2007534460A5 - - Google Patents
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- JP2007534460A5 JP2007534460A5 JP2006541405A JP2006541405A JP2007534460A5 JP 2007534460 A5 JP2007534460 A5 JP 2007534460A5 JP 2006541405 A JP2006541405 A JP 2006541405A JP 2006541405 A JP2006541405 A JP 2006541405A JP 2007534460 A5 JP2007534460 A5 JP 2007534460A5
- Authority
- JP
- Japan
- Prior art keywords
- ceramic composition
- adsorbent
- adsorption
- substrate
- coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000003463 adsorbent Substances 0.000 claims description 256
- 239000000919 ceramic Substances 0.000 claims description 206
- 239000000203 mixture Substances 0.000 claims description 185
- 238000001179 sorption measurement Methods 0.000 claims description 163
- 239000012530 fluid Substances 0.000 claims description 100
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 91
- 238000000576 coating method Methods 0.000 claims description 89
- 229910052751 metal Inorganic materials 0.000 claims description 86
- 239000002184 metal Substances 0.000 claims description 86
- -1 mercapto, acetoxy Chemical group 0.000 claims description 85
- 239000011248 coating agent Substances 0.000 claims description 81
- 239000000758 substrate Substances 0.000 claims description 79
- 229920001709 polysilazane Polymers 0.000 claims description 78
- 229920000642 polymer Polymers 0.000 claims description 71
- 239000002245 particle Substances 0.000 claims description 63
- 239000011159 matrix material Substances 0.000 claims description 54
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 52
- 239000012491 analyte Substances 0.000 claims description 50
- 239000000463 material Substances 0.000 claims description 47
- 239000006185 dispersion Substances 0.000 claims description 44
- 239000002131 composite material Substances 0.000 claims description 43
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 41
- 229910052799 carbon Inorganic materials 0.000 claims description 40
- 229910052710 silicon Inorganic materials 0.000 claims description 37
- 239000010703 silicon Substances 0.000 claims description 36
- 229920001296 polysiloxane Polymers 0.000 claims description 34
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 34
- 229920006037 cross link polymer Polymers 0.000 claims description 32
- 239000000377 silicon dioxide Substances 0.000 claims description 32
- 239000011521 glass Substances 0.000 claims description 29
- 229910052757 nitrogen Inorganic materials 0.000 claims description 29
- 239000011230 binding agent Substances 0.000 claims description 28
- 238000004587 chromatography analysis Methods 0.000 claims description 27
- 125000000217 alkyl group Chemical group 0.000 claims description 26
- 229910052739 hydrogen Inorganic materials 0.000 claims description 22
- 238000010438 heat treatment Methods 0.000 claims description 21
- 239000001257 hydrogen Substances 0.000 claims description 20
- 229920002554 vinyl polymer Polymers 0.000 claims description 18
- 238000002360 preparation method Methods 0.000 claims description 17
- 239000007790 solid phase Substances 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 14
- 238000012856 packing Methods 0.000 claims description 13
- 210000002268 wool Anatomy 0.000 claims description 13
- 125000003545 alkoxy group Chemical group 0.000 claims description 12
- 230000004888 barrier function Effects 0.000 claims description 12
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 10
- 229920000620 organic polymer Polymers 0.000 claims description 10
- 239000010457 zeolite Substances 0.000 claims description 9
- 229910021536 Zeolite Inorganic materials 0.000 claims description 7
- 238000013375 chromatographic separation Methods 0.000 claims description 7
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 7
- 239000012948 isocyanate Substances 0.000 claims description 7
- 150000002513 isocyanates Chemical class 0.000 claims description 7
- 150000002923 oximes Chemical class 0.000 claims description 7
- 125000003282 alkyl amino group Chemical group 0.000 claims description 6
- 230000009969 flowable effect Effects 0.000 claims description 6
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 6
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 6
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims description 5
- 230000000717 retained effect Effects 0.000 claims description 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 241001125840 Coryphaenidae Species 0.000 claims 1
- 239000010408 film Substances 0.000 description 92
- 238000000034 method Methods 0.000 description 74
- 239000011148 porous material Substances 0.000 description 74
- 239000010410 layer Substances 0.000 description 69
- 238000006243 chemical reaction Methods 0.000 description 54
- 239000000523 sample Substances 0.000 description 37
- 239000002904 solvent Substances 0.000 description 36
- 239000000243 solution Substances 0.000 description 35
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 32
- 239000000853 adhesive Substances 0.000 description 31
- 230000001070 adhesive effect Effects 0.000 description 31
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 26
- 150000002739 metals Chemical class 0.000 description 26
- 239000000725 suspension Substances 0.000 description 26
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 25
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 24
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 22
- 150000001875 compounds Chemical class 0.000 description 21
- XMNIXWIUMCBBBL-UHFFFAOYSA-N 2-(2-phenylpropan-2-ylperoxy)propan-2-ylbenzene Chemical compound C=1C=CC=CC=1C(C)(C)OOC(C)(C)C1=CC=CC=C1 XMNIXWIUMCBBBL-UHFFFAOYSA-N 0.000 description 20
- 239000007789 gas Substances 0.000 description 20
- 239000002243 precursor Substances 0.000 description 20
- 239000000126 substance Substances 0.000 description 19
- 239000000835 fiber Substances 0.000 description 18
- 239000007788 liquid Substances 0.000 description 17
- 229920001187 thermosetting polymer Polymers 0.000 description 17
- 125000003118 aryl group Chemical group 0.000 description 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 14
- 230000000274 adsorptive effect Effects 0.000 description 13
- 238000004458 analytical method Methods 0.000 description 13
- 239000012071 phase Substances 0.000 description 13
- 238000000862 absorption spectrum Methods 0.000 description 12
- 238000004132 cross linking Methods 0.000 description 11
- 125000004122 cyclic group Chemical group 0.000 description 11
- 238000002149 energy-dispersive X-ray emission spectroscopy Methods 0.000 description 11
- 229910001220 stainless steel Inorganic materials 0.000 description 11
- 125000004433 nitrogen atom Chemical group N* 0.000 description 10
- 230000008569 process Effects 0.000 description 10
- 238000002470 solid-phase micro-extraction Methods 0.000 description 10
- 239000010935 stainless steel Substances 0.000 description 10
- QGJOPFRUJISHPQ-UHFFFAOYSA-N Carbon disulfide Chemical compound S=C=S QGJOPFRUJISHPQ-UHFFFAOYSA-N 0.000 description 9
- 230000005526 G1 to G0 transition Effects 0.000 description 9
- 125000004429 atom Chemical group 0.000 description 9
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 9
- 230000006870 function Effects 0.000 description 9
- 238000002414 normal-phase solid-phase extraction Methods 0.000 description 9
- 229910052760 oxygen Inorganic materials 0.000 description 9
- 239000001301 oxygen Substances 0.000 description 9
- 230000002829 reductive effect Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 8
- 230000015572 biosynthetic process Effects 0.000 description 8
- 125000004432 carbon atom Chemical group C* 0.000 description 8
- 238000001723 curing Methods 0.000 description 8
- 238000009826 distribution Methods 0.000 description 8
- 150000002978 peroxides Chemical class 0.000 description 8
- 238000010926 purge Methods 0.000 description 8
- 238000012546 transfer Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 238000004566 IR spectroscopy Methods 0.000 description 7
- 229910052782 aluminium Inorganic materials 0.000 description 7
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 7
- 125000004093 cyano group Chemical group *C#N 0.000 description 7
- 238000003795 desorption Methods 0.000 description 7
- 125000003709 fluoroalkyl group Chemical group 0.000 description 7
- 125000000524 functional group Chemical group 0.000 description 7
- 238000004128 high performance liquid chromatography Methods 0.000 description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 7
- 239000003999 initiator Substances 0.000 description 7
- 239000003505 polymerization initiator Substances 0.000 description 7
- 239000002002 slurry Substances 0.000 description 7
- 239000007921 spray Substances 0.000 description 7
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 6
- 125000003358 C2-C20 alkenyl group Chemical group 0.000 description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 6
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 6
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical class [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 6
- 229910000831 Steel Inorganic materials 0.000 description 6
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 6
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 6
- 125000001309 chloro group Chemical group Cl* 0.000 description 6
- 230000001427 coherent effect Effects 0.000 description 6
- 229910052802 copper Inorganic materials 0.000 description 6
- 239000010949 copper Substances 0.000 description 6
- 239000000945 filler Substances 0.000 description 6
- 125000001153 fluoro group Chemical group F* 0.000 description 6
- 125000003055 glycidyl group Chemical group C(C1CO1)* 0.000 description 6
- 125000005641 methacryl group Chemical group 0.000 description 6
- 230000000269 nucleophilic effect Effects 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 239000010959 steel Substances 0.000 description 6
- 238000003775 Density Functional Theory Methods 0.000 description 5
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 5
- 230000000712 assembly Effects 0.000 description 5
- 238000000429 assembly Methods 0.000 description 5
- 239000012298 atmosphere Substances 0.000 description 5
- 229910002026 crystalline silica Inorganic materials 0.000 description 5
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 5
- 238000001704 evaporation Methods 0.000 description 5
- 229910021485 fumed silica Inorganic materials 0.000 description 5
- 239000000178 monomer Substances 0.000 description 5
- 230000007935 neutral effect Effects 0.000 description 5
- BNIXVQGCZULYKV-UHFFFAOYSA-N pentachloroethane Chemical compound ClC(Cl)C(Cl)(Cl)Cl BNIXVQGCZULYKV-UHFFFAOYSA-N 0.000 description 5
- 230000035699 permeability Effects 0.000 description 5
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 5
- 238000006116 polymerization reaction Methods 0.000 description 5
- 230000000379 polymerizing effect Effects 0.000 description 5
- 238000002459 porosimetry Methods 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 235000012239 silicon dioxide Nutrition 0.000 description 5
- 229910052990 silicon hydride Inorganic materials 0.000 description 5
- 239000002893 slag Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 229910052726 zirconium Inorganic materials 0.000 description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 229910003849 O-Si Inorganic materials 0.000 description 4
- 229910003872 O—Si Inorganic materials 0.000 description 4
- 229910018557 Si O Inorganic materials 0.000 description 4
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000005229 chemical vapour deposition Methods 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 238000005336 cracking Methods 0.000 description 4
- 230000032798 delamination Effects 0.000 description 4
- 239000004205 dimethyl polysiloxane Substances 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- 125000005843 halogen group Chemical group 0.000 description 4
- 150000004678 hydrides Chemical class 0.000 description 4
- 125000001183 hydrocarbyl group Chemical group 0.000 description 4
- 238000006459 hydrosilylation reaction Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 description 4
- 229910001000 nickel titanium Inorganic materials 0.000 description 4
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 4
- 239000011236 particulate material Substances 0.000 description 4
- 239000002798 polar solvent Substances 0.000 description 4
- 238000000197 pyrolysis Methods 0.000 description 4
- 238000006722 reduction reaction Methods 0.000 description 4
- 238000005070 sampling Methods 0.000 description 4
- 229910002027 silica gel Inorganic materials 0.000 description 4
- 239000000741 silica gel Substances 0.000 description 4
- LIVNPJMFVYWSIS-UHFFFAOYSA-N silicon monoxide Inorganic materials [Si-]#[O+] LIVNPJMFVYWSIS-UHFFFAOYSA-N 0.000 description 4
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 4
- 238000002411 thermogravimetry Methods 0.000 description 4
- 229910052719 titanium Inorganic materials 0.000 description 4
- 239000010936 titanium Substances 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 229910000906 Bronze Inorganic materials 0.000 description 3
- 0 CN[Si](C)N(C)N=* Chemical compound CN[Si](C)N(C)N=* 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 241000282346 Meles meles Species 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 229910018540 Si C Inorganic materials 0.000 description 3
- 239000004809 Teflon Substances 0.000 description 3
- 229920006362 Teflon® Polymers 0.000 description 3
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- 238000013459 approach Methods 0.000 description 3
- 125000004104 aryloxy group Chemical group 0.000 description 3
- 239000010974 bronze Substances 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 229910010293 ceramic material Inorganic materials 0.000 description 3
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 238000006731 degradation reaction Methods 0.000 description 3
- 238000006356 dehydrogenation reaction Methods 0.000 description 3
- 238000003618 dip coating Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011049 filling Methods 0.000 description 3
- 229920001002 functional polymer Polymers 0.000 description 3
- 229910052732 germanium Inorganic materials 0.000 description 3
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 3
- YBMRDBCBODYGJE-UHFFFAOYSA-N germanium oxide Inorganic materials O=[Ge]=O YBMRDBCBODYGJE-UHFFFAOYSA-N 0.000 description 3
- 239000001307 helium Substances 0.000 description 3
- 229910052734 helium Inorganic materials 0.000 description 3
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 3
- 239000011261 inert gas Substances 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 229910052759 nickel Inorganic materials 0.000 description 3
- 239000012454 non-polar solvent Substances 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- PVADDRMAFCOOPC-UHFFFAOYSA-N oxogermanium Chemical compound [Ge]=O PVADDRMAFCOOPC-UHFFFAOYSA-N 0.000 description 3
- 238000002161 passivation Methods 0.000 description 3
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- SCPYDCQAZCOKTP-UHFFFAOYSA-N silanol Chemical compound [SiH3]O SCPYDCQAZCOKTP-UHFFFAOYSA-N 0.000 description 3
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- 239000007858 starting material Substances 0.000 description 3
- SYBYTAAJFKOIEJ-UHFFFAOYSA-N 3-Methylbutan-2-one Chemical compound CC(C)C(C)=O SYBYTAAJFKOIEJ-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
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- 238000013006 addition curing Methods 0.000 description 2
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- 238000005515 capillary zone electrophoresis Methods 0.000 description 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
- 238000005524 ceramic coating Methods 0.000 description 2
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- 229910021419 crystalline silicon Inorganic materials 0.000 description 2
- 230000009849 deactivation Effects 0.000 description 2
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- 239000012153 distilled water Substances 0.000 description 2
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- 238000004817 gas chromatography Methods 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 238000001879 gelation Methods 0.000 description 2
- 239000010439 graphite Substances 0.000 description 2
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- 238000007871 hydride transfer reaction Methods 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 230000005661 hydrophobic surface Effects 0.000 description 2
- 238000012844 infrared spectroscopy analysis Methods 0.000 description 2
- 238000002329 infrared spectrum Methods 0.000 description 2
- 238000005040 ion trap Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 239000012705 liquid precursor Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000004949 mass spectrometry Methods 0.000 description 2
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- 238000013008 moisture curing Methods 0.000 description 2
- 239000002808 molecular sieve Substances 0.000 description 2
- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
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| US20080023630A1 (en) * | 2005-11-22 | 2008-01-31 | Ciphergen Biosystems Inc. | Polymer probe doped with conductive material for mass spectrometry |
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| PT2251454E (pt) | 2009-05-13 | 2014-10-01 | Sio2 Medical Products Inc | Revestimento e inspeção de vaso |
| US7985188B2 (en) | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
| US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
| WO2012047945A2 (en) | 2010-10-05 | 2012-04-12 | Silcotek Corp. | Wear resistant coating, article, and method |
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| US8657483B2 (en) | 2010-09-03 | 2014-02-25 | Cabot Norit Americas, Inc. | Apparatuses for dilute phase impregnation of a milled sorbent with a chemical compound in an aqueous solution |
| US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
| US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
| US9821418B2 (en) | 2011-06-30 | 2017-11-21 | International Business Machines Corporation | Adsorption heat exchanger devices |
| US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
| CA2855353C (en) | 2011-11-11 | 2021-01-19 | Sio2 Medical Products, Inc. | Passivation, ph protective or lubricity coating for pharmaceutical package, coating process and apparatus |
| US9856400B2 (en) | 2012-04-27 | 2018-01-02 | Burning Bush Group, Llc | High performance silicon based coating compositions |
| EP2846755A1 (en) | 2012-05-09 | 2015-03-18 | SiO2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
| US10138381B2 (en) | 2012-05-10 | 2018-11-27 | Burning Bush Group, Llc | High performance silicon based thermal coating compositions |
| US8809445B2 (en) * | 2012-06-22 | 2014-08-19 | Texas Research International, Inc. | Room temperature cured vinyl silazane compositions |
| US20150297800A1 (en) | 2012-07-03 | 2015-10-22 | Sio2 Medical Products, Inc. | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS |
| JP6158921B2 (ja) | 2012-07-03 | 2017-07-05 | バーニング ブッシュ グループ、 エルエルシー | 高性能ケイ素系コーティング組成物 |
| DE102012014335A1 (de) | 2012-07-19 | 2014-01-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Dispersion, Verfahren zur Beschichtung von Gegenstädenmit dieser Dispersion und Verwendung der Dispersion |
| US9733222B2 (en) | 2012-10-03 | 2017-08-15 | Waters Technologies Corporation | Rapid analysis of steroids and steroid derivatives |
| US9664626B2 (en) | 2012-11-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Coating inspection method |
| WO2014078666A1 (en) | 2012-11-16 | 2014-05-22 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
| US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
| AU2013352436B2 (en) | 2012-11-30 | 2018-10-25 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition on medical syringes, cartridges, and the like |
| US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
| US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
| CN105392916B (zh) | 2013-03-11 | 2019-03-08 | Sio2医药产品公司 | 涂布包装材料 |
| EP2971227B1 (en) | 2013-03-15 | 2017-11-15 | Si02 Medical Products, Inc. | Coating method. |
| US10767259B2 (en) | 2013-07-19 | 2020-09-08 | Agilent Technologies, Inc. | Components with an atomic layer deposition coating and methods of producing the same |
| US20150024152A1 (en) * | 2013-07-19 | 2015-01-22 | Agilent Technologies, Inc. | Metal components with inert vapor phase coating on internal surfaces |
| US9006355B1 (en) * | 2013-10-04 | 2015-04-14 | Burning Bush Group, Llc | High performance silicon-based compositions |
| WO2015148471A1 (en) | 2014-03-28 | 2015-10-01 | Sio2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
| JP6486161B2 (ja) * | 2015-03-24 | 2019-03-20 | 東京応化工業株式会社 | シリル化剤薬液の調製方法及び表面処理方法 |
| KR102786617B1 (ko) | 2015-08-18 | 2025-03-26 | 에스아이오2 메디컬 프로덕츠, 엘엘씨 | 산소 전달률이 낮은, 의약품 및 다른 제품의 포장용기 |
| US10876206B2 (en) | 2015-09-01 | 2020-12-29 | Silcotek Corp. | Thermal chemical vapor deposition coating |
| EP3672723B1 (en) | 2017-08-24 | 2023-10-18 | Sigma-Aldrich Co. LLC | Method for making improved hlb copolymers |
| US11161324B2 (en) | 2017-09-13 | 2021-11-02 | Silcotek Corp. | Corrosion-resistant coated article and thermal chemical vapor deposition coating process |
| WO2019165249A1 (en) * | 2018-02-23 | 2019-08-29 | Silcotek Corp | Liquid chromatography technique |
| WO2020174402A1 (en) * | 2019-02-27 | 2020-09-03 | Waters Technologies Corporation | Coated flow path components for chromatographic effects |
| US11747341B2 (en) | 2019-03-04 | 2023-09-05 | Waters Technologies Corporation | Methods of use for low-bind polypropylene plates and vials |
| CN113677428A (zh) | 2019-04-25 | 2021-11-19 | 圣戈本陶瓷及塑料股份有限公司 | 吸附剂颗粒及其形成方法 |
| US11724963B2 (en) | 2019-05-01 | 2023-08-15 | Corning Incorporated | Pharmaceutical packages with coatings comprising polysilazane |
| WO2020252306A1 (en) | 2019-06-14 | 2020-12-17 | Silcotek Corp. | Nano-wire growth |
| KR102317614B1 (ko) | 2020-05-29 | 2021-10-27 | 한국과학기술연구원 | 금속 컬럼을 제조하는 방법 |
| US12473635B2 (en) | 2020-06-03 | 2025-11-18 | Silcotek Corp. | Dielectric article |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5534258A (en) * | 1978-09-01 | 1980-03-10 | Tokyo Denshi Kagaku Kabushiki | Coating solution for forming silica film |
| GB2077710B (en) | 1980-06-11 | 1983-10-12 | Nat Res Dev | Synthesising a polysilane |
| US5055431A (en) * | 1985-04-26 | 1991-10-08 | Sri International | Polysilazanes and related compositions, processes and uses |
| US5008422A (en) * | 1985-04-26 | 1991-04-16 | Sri International | Polysilazanes and related compositions, processes and uses |
| US4680201A (en) * | 1985-10-30 | 1987-07-14 | Stellan Hjerten | Coating for electrophoresis tube |
| DE3717209A1 (de) * | 1987-05-22 | 1988-12-01 | Diagen Inst Molekularbio | Mittel zur selektiven adsorption von biopolymeren |
| US5080844A (en) * | 1987-08-31 | 1992-01-14 | Gte Laboratories Incorporated | SI3N4 process using polysilane or polysilazane as a binder |
| GB8805992D0 (en) * | 1988-03-14 | 1988-04-13 | Shell Int Research | Process for preparing non-porous membrane layers |
| US5325916A (en) * | 1989-07-28 | 1994-07-05 | Uop | Method of coating aluminum substrates with solid adsorbent |
| US4941893B1 (en) * | 1989-09-19 | 1996-07-30 | Advanced Silicon Materials Inc | Gas separation by semi-permeable membranes |
| US5171736A (en) | 1989-10-16 | 1992-12-15 | Massachusetts Institute Of Technology | Preceramic organosilicon-boron polymers |
| US5208192A (en) * | 1990-01-12 | 1993-05-04 | Ethyl Corporation | Preceramic polysilazane compositions |
| JP2844896B2 (ja) * | 1990-10-17 | 1999-01-13 | 信越化学工業株式会社 | 耐熱性絶縁塗料 |
| JP2501040B2 (ja) * | 1990-12-17 | 1996-05-29 | 信越化学工業株式会社 | 離型性オルガノポリシロキサン組成物およびその硬化物 |
| US5192406A (en) * | 1991-01-09 | 1993-03-09 | Supelco | Deactivated capillary columns for use in capillary electrophoresis |
| JPH0517108A (ja) * | 1991-07-05 | 1993-01-26 | Kansai Shin Gijutsu Kenkyusho:Kk | 改質粉体及び改質粉体の製造方法 |
| US5457151A (en) * | 1991-09-24 | 1995-10-10 | Southwest Research Institute | Polysilazane adhesive composition |
| US5349117A (en) * | 1992-07-08 | 1994-09-20 | Mobil Oil Corp. | Process for sorption separation |
| US5405655A (en) * | 1992-11-19 | 1995-04-11 | Sri International | Temperature-resistant and/or nonwetting coatings of cured, silicon-containing polymers |
| US5447617A (en) * | 1994-01-25 | 1995-09-05 | Beckman Instruments, Inc. | Coated capillary columns and electrophoretic separation methods for their use |
| US5653875A (en) * | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
| JP3517934B2 (ja) | 1994-03-24 | 2004-04-12 | 昭和電工株式会社 | シリコン膜の形成方法 |
| US5558908A (en) * | 1994-11-07 | 1996-09-24 | Lanxide Technology Company, Lp | Protective compositions and methods of making same |
| DE69633962T2 (de) * | 1995-01-27 | 2005-12-01 | Northeastern University, Boston | Verfahren zum Bilden einer kovalent gebundenen hydrophilen Schicht auf Basis von Polyvinyl-Alkohol für die Kapillarelektrophorese |
| AU6973296A (en) * | 1995-09-12 | 1997-04-01 | Gelest, Inc. | Beta-substituted organosilsesquioxanes and use thereof |
| JPH0980038A (ja) | 1995-09-14 | 1997-03-28 | Yuji Takayama | ガスクロマトグラフ用の金属キャピラリ−カラム及びその製造方法 |
| JPH09157593A (ja) | 1995-12-13 | 1997-06-17 | Showa Electric Wire & Cable Co Ltd | 耐熱性塗料 |
| JPH10183369A (ja) * | 1996-12-20 | 1998-07-14 | Suzuki Motor Corp | アルミニウム材の表面処理方法 |
| DE19756203A1 (de) * | 1996-12-23 | 1998-09-24 | Voith Sulzer Papiermasch Gmbh | Naßpartie und Verfahren zur Herstellung einer Faserstoffbahn |
| JP3691619B2 (ja) * | 1997-01-20 | 2005-09-07 | ジーエルサイエンス株式会社 | 液体クロマトグラフィー用充填剤及びその処理方法 |
| US6048457A (en) * | 1997-02-26 | 2000-04-11 | Millipore Corporation | Cast membrane structures for sample preparation |
| JPH10288571A (ja) * | 1997-04-14 | 1998-10-27 | Unie Flex:Kk | ピペットチップ及びそれを用いた物質抽出方法 |
| DE19732865A1 (de) | 1997-07-30 | 1999-02-04 | Basf Ag | Siliciumdioxid enthaltender Feststoff mit großer Oberfläche |
| EP1032546A4 (en) * | 1997-09-04 | 2002-03-20 | Pall Corp | POROUS CERAMIC STRUCTURES AND MANUFACTURING METHODS THEREOF |
| JPH11170428A (ja) | 1997-12-12 | 1999-06-29 | Benkan Corp | ガス吸着抑制化基材 |
| US5928515A (en) * | 1997-12-12 | 1999-07-27 | Uop Llc | Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers |
| DE19800022A1 (de) * | 1998-01-02 | 1999-07-08 | Huels Silicone Gmbh | Verfahren zur Herstellung von Siliconpolymer-Feststoff-Mischungen für fließfähige RTV2-Silicon-Massen mit niedriger Fließgrenze |
| US6511760B1 (en) * | 1998-02-27 | 2003-01-28 | Restek Corporation | Method of passivating a gas vessel or component of a gas transfer system using a silicon overlay coating |
| JP2000026727A (ja) * | 1998-07-06 | 2000-01-25 | Dow Corning Toray Silicone Co Ltd | 硬化性シリコーンレジン組成物 |
| US6329488B1 (en) * | 1998-11-10 | 2001-12-11 | C. R. Bard, Inc. | Silane copolymer coatings |
| US6444326B1 (en) * | 1999-03-05 | 2002-09-03 | Restek Corporation | Surface modification of solid supports through the thermal decomposition and functionalization of silanes |
| US6143057A (en) * | 1999-04-23 | 2000-11-07 | The Boc Group, Inc. | Adsorbents and adsorptive separation process |
| US20020096431A1 (en) * | 1999-09-01 | 2002-07-25 | Pierre Sevigny | Apparatus for the manufacture of a disposable electrophoresis cassette and method thereof |
| JP2001098220A (ja) * | 1999-09-28 | 2001-04-10 | Kankyo Device Kenkyusho:Kk | 防藻用光触媒コーティング及びこのコーティングを有する物品 |
| US6329487B1 (en) * | 1999-11-12 | 2001-12-11 | Kion Corporation | Silazane and/or polysilazane compounds and methods of making |
| KR100562815B1 (ko) * | 2000-03-13 | 2006-03-23 | 제이에스알 가부시끼가이샤 | 실리콘막 형성용 용액 조성물 및 실리콘막의 형성 방법 |
| US6416716B1 (en) * | 2001-04-20 | 2002-07-09 | Ashok Kumar Shukla | Sample preparation device with embedded separation media |
| US6534184B2 (en) * | 2001-02-26 | 2003-03-18 | Kion Corporation | Polysilazane/polysiloxane block copolymers |
| JP2003075421A (ja) * | 2001-08-31 | 2003-03-12 | Shiseido Co Ltd | カラム充填剤及びその製造方法 |
| JP4722830B2 (ja) | 2003-02-10 | 2011-07-13 | ウオーターズ・テクノロジーズ・コーポレイシヨン | クロマトグラフィー分離および抽出用シロキサン固定化粒子状固定相 |
| EP1713577B1 (en) * | 2003-11-20 | 2020-05-13 | Sigma-Aldrich Co. LLC | Polysilazane thermosetting polymers for use in chromatographic systems and applications |
-
2004
- 2004-11-19 EP EP04811535.6A patent/EP1713577B1/en not_active Expired - Lifetime
- 2004-11-19 US US10/993,168 patent/US7815864B2/en active Active
- 2004-11-19 CA CA2546898A patent/CA2546898C/en not_active Expired - Lifetime
- 2004-11-19 WO PCT/US2004/038832 patent/WO2005052544A2/en not_active Ceased
- 2004-11-19 JP JP2006541405A patent/JP5580507B2/ja not_active Expired - Lifetime
- 2004-11-19 CA CA2945455A patent/CA2945455C/en not_active Expired - Lifetime
-
2008
- 2008-02-08 US US12/028,582 patent/US8088350B2/en not_active Expired - Lifetime
- 2008-02-08 US US12/028,596 patent/US20080159916A1/en not_active Abandoned
- 2008-09-29 US US12/240,401 patent/US7875738B2/en not_active Expired - Lifetime
- 2008-09-29 US US12/240,424 patent/US8092770B2/en not_active Expired - Lifetime
-
2012
- 2012-05-14 JP JP2012110914A patent/JP5806639B2/ja not_active Expired - Lifetime
-
2013
- 2013-09-18 JP JP2013193327A patent/JP5940034B2/ja not_active Expired - Lifetime
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