JP2007529223A - 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 - Google Patents

選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 Download PDF

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JP2007529223A
JP2007529223A JP2007504008A JP2007504008A JP2007529223A JP 2007529223 A JP2007529223 A JP 2007529223A JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007529223 A JP2007529223 A JP 2007529223A
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vector
polypeptide
antibody
cell
cells
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ホリー プレンティス，
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Biogen Inc
Biogen MA Inc
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Biogen Inc
Biogen Idec Inc
Biogen Idec MA Inc
Biogen MA Inc
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JP2007504008A 2004-03-15 2005-03-15 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 Pending JP2007529223A (ja)

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US55347804P 2004-03-15 2004-03-15
PCT/US2005/008473 WO2005089285A2 (en) 2004-03-15 2005-03-15 Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing

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JP2007529223A true JP2007529223A (ja) 2007-10-25
JP2007529223A5 JP2007529223A5 (https=) 2008-05-01

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US (2) US7569362B2 (https=)
EP (1) EP1733034A4 (https=)
JP (1) JP2007529223A (https=)
KR (1) KR20070004026A (https=)
CN (1) CN1961071A (https=)
AU (1) AU2005222963B2 (https=)
BR (1) BRPI0508862A (https=)
CA (1) CA2559280A1 (https=)
IL (1) IL178051A (https=)
WO (1) WO2005089285A2 (https=)

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JP2016514477A (ja) * 2013-03-30 2016-05-23 ウーシャ バイオテック リミテッド 哺乳動物細胞内で生物活性タンパク質を発現させるための方法および構築物
JP2016528896A (ja) * 2013-08-06 2016-09-23 グレンマーク ファーマシューティカルズ， エセ．アー． 真核細胞においてポリペプチドを発現させるための発現構築物及び方法
JP2022511227A (ja) * 2018-07-17 2022-01-31 ニューロマイオン インコーポレイテッド Ｉｇｆ－１異型体を発現させるｄｎａコンストラクトを用いた神経病症の治療
JP2022546408A (ja) * 2019-08-30 2022-11-04 ベイラー カレッジ オブ メディスン 遺伝子発現を調節するためのシステム
JP2024500194A (ja) * 2021-11-26 2024-01-05 勁帆生物医薬科技（武漢）有限公司 重複オープンリーディングフレームを含む遺伝子の発現カセット、及び昆虫細胞におけるこの発現カセット使用

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KR100907221B1 (ko) * 2009-01-22 2009-07-10 한국과학기술원 새로운 조성의 황색 발광 Ｃｅ3+부활 칼슘 실리케이트 황색형광체를 포함하는 백색 발광 다이오드
US9481882B2 (en) 2010-03-31 2016-11-01 Tokyo University Of Science Foundation Constitution of tool for analyzing biomolecular interaction and analysis method using same
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CN104053671A (zh) 2011-11-01 2014-09-17 生态学有限公司 治疗癌症的抗体和方法
US9221907B2 (en) 2011-11-01 2015-12-29 Bionomics Inc. Anti-GPR49 monoclonal antibodies
US10598653B2 (en) 2011-11-01 2020-03-24 Bionomics Inc. Methods of blocking cancer stem cell growth
ES2791758T3 (es) * 2011-12-22 2020-11-05 Hoffmann La Roche Organización de vectores de expresión, procedimientos de generación de células de producción novedosos y su uso para la producción recombinante de polipéptidos
GB2500113A (en) 2012-03-05 2013-09-11 Oxitec Ltd Arthropod male germline gene expression system
GB201303932D0 (en) 2013-03-05 2013-04-17 Oxitec Ltd Muscle actin promoter
CA2944649C (en) 2014-04-04 2022-06-21 Bionomics, Inc. Humanized antibodies that bind lgr5
GB2526867A (en) 2014-06-05 2015-12-09 Oxitec Ltd Gene expression system
WO2017161414A1 (en) 2016-03-22 2017-09-28 Bionomics Limited Administration of an anti-lgr5 monoclonal antibody
BR112019002771A2 (pt) 2016-08-12 2019-05-14 Oxitec Ltd polinucleotídeo de módulo de controle de união de doublesex, sistema de expressão de gene, plasmídeo vetor de expressão, inseto geneticamente engenheirado, métodos para produzir insetos geneticamente engenheirados, para cultivar seletivamente insetos macho geneticamente engenheirados, para reduzir uma população de inseto selvagem, para criar um mosquito aedes aegypti transgênico e para detectar a presença de uma molécula de dna, local alvo cromossômico de aedes aegypti, mosquito aedes aegypti geneticamente engenheirado, molécula de dna, e, kit de detecção de dna.
CN109790214B (zh) 2016-09-29 2022-09-06 豪夫迈·罗氏有限公司 用于选择产生多肽的细胞的改进方法
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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016514477A (ja) * 2013-03-30 2016-05-23 ウーシャ バイオテック リミテッド 哺乳動物細胞内で生物活性タンパク質を発現させるための方法および構築物
JP2016528896A (ja) * 2013-08-06 2016-09-23 グレンマーク ファーマシューティカルズ， エセ．アー． 真核細胞においてポリペプチドを発現させるための発現構築物及び方法
JP2020202840A (ja) * 2013-08-06 2020-12-24 イクノス サイエンシズ エスエー 真核細胞においてポリペプチドを発現させるための発現構築物及び方法
JP2022177131A (ja) * 2013-08-06 2022-11-30 イクノス サイエンシズ エスエー 真核細胞においてポリペプチドを発現させるための発現構築物及び方法
JP2022511227A (ja) * 2018-07-17 2022-01-31 ニューロマイオン インコーポレイテッド Ｉｇｆ－１異型体を発現させるｄｎａコンストラクトを用いた神経病症の治療
JP7413629B2 (ja) 2018-07-17 2024-01-16 ヘリックスミス カンパニー， リミテッド Ｉｇｆ－１異型体を発現させるｄｎａコンストラクトを用いた神経病症の治療
JP2022546408A (ja) * 2019-08-30 2022-11-04 ベイラー カレッジ オブ メディスン 遺伝子発現を調節するためのシステム
JP2025118711A (ja) * 2019-08-30 2025-08-13 ベイラー カレッジ オブ メディスン 遺伝子発現を調節するためのシステム
JP7737152B2 (ja) 2019-08-30 2025-09-10 ベイラー カレッジ オブ メディスン 遺伝子発現を調節するためのシステム
JP2024500194A (ja) * 2021-11-26 2024-01-05 勁帆生物医薬科技（武漢）有限公司 重複オープンリーディングフレームを含む遺伝子の発現カセット、及び昆虫細胞におけるこの発現カセット使用
JP7560896B2 (ja) 2021-11-26 2024-10-03 勁帆生物医薬科技（武漢）有限公司 重複オープンリーディングフレームを含む遺伝子の発現カセット、及び昆虫細胞におけるこの発現カセット使用

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US20100009410A1 (en) 2010-01-14
KR20070004026A (ko) 2007-01-05
CN1961071A (zh) 2007-05-09
WO2005089285A2 (en) 2005-09-29
EP1733034A4 (en) 2010-01-20
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