JP2007529223A5 - - Google Patents

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Publication number
JP2007529223A5
JP2007529223A5 JP2007504008A JP2007504008A JP2007529223A5 JP 2007529223 A5 JP2007529223 A5 JP 2007529223A5 JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007529223 A5 JP2007529223 A5 JP 2007529223A5
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JP
Japan
Prior art keywords
vector
polypeptide
cell
antibody
exon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007504008A
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English (en)
Japanese (ja)
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JP2007529223A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/008473 external-priority patent/WO2005089285A2/en
Publication of JP2007529223A publication Critical patent/JP2007529223A/ja
Publication of JP2007529223A5 publication Critical patent/JP2007529223A5/ja
Pending legal-status Critical Current

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JP2007504008A 2004-03-15 2005-03-15 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 Pending JP2007529223A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55347804P 2004-03-15 2004-03-15
PCT/US2005/008473 WO2005089285A2 (en) 2004-03-15 2005-03-15 Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing

Publications (2)

Publication Number Publication Date
JP2007529223A JP2007529223A (ja) 2007-10-25
JP2007529223A5 true JP2007529223A5 (https=) 2008-05-01

Family

ID=34994241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007504008A Pending JP2007529223A (ja) 2004-03-15 2005-03-15 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物

Country Status (10)

Country Link
US (2) US7569362B2 (https=)
EP (1) EP1733034A4 (https=)
JP (1) JP2007529223A (https=)
KR (1) KR20070004026A (https=)
CN (1) CN1961071A (https=)
AU (1) AU2005222963B2 (https=)
BR (1) BRPI0508862A (https=)
CA (1) CA2559280A1 (https=)
IL (1) IL178051A (https=)
WO (1) WO2005089285A2 (https=)

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CA2559280A1 (en) * 2004-03-15 2005-09-29 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
US20090183269A1 (en) * 2006-02-10 2009-07-16 Oxitec Limited Gene expression system using alternative splicing in insects
GB2443186A (en) 2006-10-25 2008-04-30 Oxitec Ltd Expression system for mediating alternative splicing
AU2007245164A1 (en) 2006-03-28 2007-11-08 Biogen Idec Ma Inc. Anti-IGF-IR antibodies and uses thereof
US20090305343A1 (en) * 2006-05-16 2009-12-10 Millegen Method For Expressing Polypeptides In Eukaryotic Cells Using Alternative Splicing
EP2027273B1 (en) * 2006-05-17 2016-04-13 F. Hoffmann-La Roche AG Polypeptide producing cells
US20080045419A1 (en) * 2006-08-18 2008-02-21 University Of North Texas Health Science Center At Fort Worth Screening Assay
SG185302A1 (en) * 2007-10-15 2012-11-29 Chugai Pharmaceutical Co Ltd Method for production of antibody
US7947495B2 (en) * 2007-11-01 2011-05-24 Abbott Biotherapeutics Corp. Immunoglobulin display vectors
KR100907221B1 (ko) * 2009-01-22 2009-07-10 한국과학기술원 새로운 조성의 황색 발광 Ｃｅ3+부활 칼슘 실리케이트 황색형광체를 포함하는 백색 발광 다이오드
US9481882B2 (en) 2010-03-31 2016-11-01 Tokyo University Of Science Foundation Constitution of tool for analyzing biomolecular interaction and analysis method using same
WO2013067057A1 (en) 2011-11-01 2013-05-10 Bionomics, Inc. Anti-gpr49 antibodies
CN104053671A (zh) 2011-11-01 2014-09-17 生态学有限公司 治疗癌症的抗体和方法
US9221907B2 (en) 2011-11-01 2015-12-29 Bionomics Inc. Anti-GPR49 monoclonal antibodies
US10598653B2 (en) 2011-11-01 2020-03-24 Bionomics Inc. Methods of blocking cancer stem cell growth
ES2791758T3 (es) * 2011-12-22 2020-11-05 Hoffmann La Roche Organización de vectores de expresión, procedimientos de generación de células de producción novedosos y su uso para la producción recombinante de polipéptidos
GB2500113A (en) 2012-03-05 2013-09-11 Oxitec Ltd Arthropod male germline gene expression system
GB201303932D0 (en) 2013-03-05 2013-04-17 Oxitec Ltd Muscle actin promoter
AU2014246731A1 (en) * 2013-03-30 2015-11-19 Usha Biotech Limited Methods and constructs for expressing biologically active proteins in mammalian cells
KR20200044154A (ko) * 2013-08-06 2020-04-28 아이크노스 사이언스 에스. 아. 진핵세포의 폴리펩티드 발현 방법 및 발현 구조체
CA2944649C (en) 2014-04-04 2022-06-21 Bionomics, Inc. Humanized antibodies that bind lgr5
GB2526867A (en) 2014-06-05 2015-12-09 Oxitec Ltd Gene expression system
WO2017161414A1 (en) 2016-03-22 2017-09-28 Bionomics Limited Administration of an anti-lgr5 monoclonal antibody
BR112019002771A2 (pt) 2016-08-12 2019-05-14 Oxitec Ltd polinucleotídeo de módulo de controle de união de doublesex, sistema de expressão de gene, plasmídeo vetor de expressão, inseto geneticamente engenheirado, métodos para produzir insetos geneticamente engenheirados, para cultivar seletivamente insetos macho geneticamente engenheirados, para reduzir uma população de inseto selvagem, para criar um mosquito aedes aegypti transgênico e para detectar a presença de uma molécula de dna, local alvo cromossômico de aedes aegypti, mosquito aedes aegypti geneticamente engenheirado, molécula de dna, e, kit de detecção de dna.
CN109790214B (zh) 2016-09-29 2022-09-06 豪夫迈·罗氏有限公司 用于选择产生多肽的细胞的改进方法
AR117409A1 (es) 2018-03-29 2021-08-04 Oxitec Ltd Noctuidas autolimitantes
EP3823981A4 (en) * 2018-07-17 2022-04-06 Neuromyon Inc. TREATMENT OF NEUROPATHY WITH DNA CONSTRUCTS EXPRESSING IGF-1 ISOFORMS
CN115279902A (zh) * 2019-08-30 2022-11-01 贝勒医学院 用于调控基因表达的系统
CN114150021B (zh) * 2021-11-26 2022-10-28 劲帆生物医药科技（武汉）有限公司 一种包含重叠开放阅读框的基因的表达盒及其在昆虫细胞中的应用

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CA2559280A1 (en) * 2004-03-15 2005-09-29 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing

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