JP2007528388A5 - - Google Patents
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- Publication number
- JP2007528388A5 JP2007528388A5 JP2007502436A JP2007502436A JP2007528388A5 JP 2007528388 A5 JP2007528388 A5 JP 2007528388A5 JP 2007502436 A JP2007502436 A JP 2007502436A JP 2007502436 A JP2007502436 A JP 2007502436A JP 2007528388 A5 JP2007528388 A5 JP 2007528388A5
- Authority
- JP
- Japan
- Prior art keywords
- mixtures
- composition
- fatty acid
- solid
- phthalate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 18
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 150000004665 fatty acids Chemical class 0.000 claims 5
- -1 polyoxyethylene glycerol Polymers 0.000 claims 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 4
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 claims 4
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 claims 4
- 229960004845 drospirenone Drugs 0.000 claims 4
- 229920001477 hydrophilic polymer Polymers 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 2
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 2
- 108010010803 Gelatin Proteins 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 2
- 229960001631 carbomer Drugs 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 2
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 229960005168 croscarmellose Drugs 0.000 claims 2
- 229960000913 crospovidone Drugs 0.000 claims 2
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 229920000159 gelatin Polymers 0.000 claims 2
- 239000008273 gelatin Substances 0.000 claims 2
- 235000019322 gelatine Nutrition 0.000 claims 2
- 235000011852 gelatine desserts Nutrition 0.000 claims 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 2
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 2
- 229940071676 hydroxypropylcellulose Drugs 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 229940117841 methacrylic acid copolymer Drugs 0.000 claims 2
- 229920003145 methacrylic acid copolymer Polymers 0.000 claims 2
- 229920000609 methyl cellulose Polymers 0.000 claims 2
- 239000001923 methylcellulose Substances 0.000 claims 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 229940093429 polyethylene glycol 6000 Drugs 0.000 claims 2
- 229920002689 polyvinyl acetate Polymers 0.000 claims 2
- 239000011118 polyvinyl acetate Substances 0.000 claims 2
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 2
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 229940023144 sodium glycolate Drugs 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 150000003626 triacylglycerols Chemical class 0.000 claims 2
- JEJAMASKDTUEBZ-UHFFFAOYSA-N tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate Chemical compound BrCC(C)(C)C(Br)(Br)OP(=O)(OC(Br)(Br)C(C)(C)CBr)OC(Br)(Br)C(C)(C)CBr JEJAMASKDTUEBZ-UHFFFAOYSA-N 0.000 claims 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 2
- 235000019871 vegetable fat Nutrition 0.000 claims 2
- 239000008158 vegetable oil Substances 0.000 claims 2
- 239000001993 wax Substances 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 1
- 229940011871 estrogen Drugs 0.000 claims 1
- 239000000262 estrogen Substances 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 125000005908 glyceryl ester group Chemical group 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 239000007909 solid dosage form Substances 0.000 claims 1
- 239000008247 solid mixture Substances 0.000 claims 1
- 238000000527 sonication Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55135504P | 2004-03-10 | 2004-03-10 | |
| EP04075713 | 2004-03-10 | ||
| PCT/IB2005/000665 WO2005087194A1 (en) | 2004-03-10 | 2005-03-10 | Compositions comprising drospirenone molecularly dispersed |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010068645A Division JP2010150289A (ja) | 2004-03-10 | 2010-03-24 | 分子分散されたドロスピレノンを含む組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007528388A JP2007528388A (ja) | 2007-10-11 |
| JP2007528388A5 true JP2007528388A5 (enExample) | 2008-04-24 |
Family
ID=34961545
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502436A Pending JP2007528388A (ja) | 2004-03-10 | 2005-03-10 | 分子分散されたドロスピレノンを含む組成物 |
| JP2010068645A Pending JP2010150289A (ja) | 2004-03-10 | 2010-03-24 | 分子分散されたドロスピレノンを含む組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010068645A Pending JP2010150289A (ja) | 2004-03-10 | 2010-03-24 | 分子分散されたドロスピレノンを含む組成物 |
Country Status (22)
| Country | Link |
|---|---|
| EP (2) | EP1748756B1 (enExample) |
| JP (2) | JP2007528388A (enExample) |
| KR (1) | KR20060130723A (enExample) |
| AT (2) | ATE429900T1 (enExample) |
| AU (2) | AU2005221402B2 (enExample) |
| BR (1) | BRPI0508612A (enExample) |
| CA (1) | CA2558393A1 (enExample) |
| CR (1) | CR8631A (enExample) |
| CU (1) | CU20060173A7 (enExample) |
| CY (1) | CY1109265T1 (enExample) |
| DE (1) | DE602005014227D1 (enExample) |
| DK (1) | DK1748756T3 (enExample) |
| EA (1) | EA012570B1 (enExample) |
| EC (1) | ECSP066901A (enExample) |
| ES (1) | ES2325591T3 (enExample) |
| HR (1) | HRP20090381T1 (enExample) |
| IL (1) | IL177893A0 (enExample) |
| NZ (1) | NZ549792A (enExample) |
| PL (1) | PL1748756T3 (enExample) |
| PT (1) | PT1748756E (enExample) |
| SI (1) | SI1748756T1 (enExample) |
| WO (1) | WO2005087194A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY142989A (en) | 2004-03-10 | 2011-02-14 | Bayer Schering Pharma Ag | Stabilised supersaturated solids of lipophilic drugs |
| US8475838B2 (en) | 2005-06-03 | 2013-07-02 | Sandoz Ag | Rapidly-dissolving pharmaceutical composition for inhibiting ovulation |
| EP1767194A1 (de) * | 2005-06-09 | 2007-03-28 | Helm AG | Verfahren zur Herstellung von Adsorbaten des Drospirenons |
| JP2009513642A (ja) * | 2005-10-25 | 2009-04-02 | アボット・ラボラトリーズ | 低水溶解度の薬剤を含む製剤およびそれの使用方法 |
| WO2009138224A1 (en) * | 2008-05-14 | 2009-11-19 | Helm Ag | Pharmaceutical composition comprising drospirenone |
| HRP20170929T1 (hr) | 2008-09-17 | 2017-09-22 | Chiasma Inc. | Farmaceutski pripravci i odgovarajući postupci za isporuku |
| US8512745B2 (en) | 2008-12-08 | 2013-08-20 | Laboratoire Hra Pharma | Ulipristal acetate tablets |
| CA2752805A1 (en) * | 2009-02-18 | 2010-08-26 | Bayer Pharma Aktiengesellschaft | Formulation comprising drospirenone for subcutaneous or intramuscular administration |
| PT3403654T (pt) | 2009-10-01 | 2019-09-05 | Adare Dev I L P | Composições de corticosteroide administradas oralmente |
| AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
| US10849857B2 (en) | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
| AU2011287955B2 (en) | 2010-08-04 | 2015-07-09 | Grünenthal GmbH | Pharmaceutical dosage form comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of neuropathic pain |
| US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
| US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| CN103040725B (zh) * | 2012-12-26 | 2015-01-21 | 武汉九珑人福药业有限责任公司 | 一种利用研磨改善屈螺酮溶出的方法及屈螺酮固体分散体 |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| EP3013154B1 (en) * | 2013-06-25 | 2019-08-07 | Olam International Limited | Process for producing dark brown natural cocoa |
| WO2015034678A2 (en) | 2013-09-06 | 2015-03-12 | Aptalis Pharmatech, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
| US10098894B2 (en) | 2014-07-29 | 2018-10-16 | Therapeuticsmd, Inc. | Transdermal cream |
| AU2016215350B2 (en) | 2015-02-03 | 2021-11-25 | Amryt Endo, Inc. | Method of treating diseases |
| MX2017011469A (es) * | 2015-03-10 | 2018-01-23 | Shionogi Inc | Dispersiones sólidas. |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| TWI777515B (zh) | 2016-08-18 | 2022-09-11 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5770815A (en) * | 1980-10-21 | 1982-05-01 | Furointo Sangyo Kk | Absorption improver |
| JPS5942313A (ja) * | 1982-09-01 | 1984-03-08 | Teijin Ltd | ポリビニルポリピロリドンを用いた製剤 |
| JPH0723303B2 (ja) * | 1986-03-07 | 1995-03-15 | 株式会社資生堂 | 難溶性薬物含有マイクロエマルシヨン製剤 |
| DE3702029A1 (de) * | 1987-01-24 | 1988-08-04 | Basf Ag | Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung |
| DE3916112A1 (de) | 1989-05-16 | 1990-11-22 | Schering Ag | Dihydrospirorenon als antiandrogen |
| DE4326240A1 (de) * | 1993-08-02 | 1995-02-09 | Schering Ag | 15,15-Dialkyl-substituierte Derivate des Estradiols |
| EP0952770A4 (en) * | 1995-09-07 | 1999-12-22 | Fuisz Technologies Ltd | SYSTEM FOR MAKING SUBSTANTIALLY NON-SOLUBLE BIOALTERANT AGENTS BIOAVAILABLE |
| US5789442A (en) * | 1996-01-18 | 1998-08-04 | Schering Aktiengesellschaft | Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents |
| AU3843999A (en) * | 1998-05-07 | 1999-11-23 | Elan Corporation, Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
| RS50262B2 (sr) * | 1999-08-31 | 2018-10-31 | Bayer Pharma AG | Farmaceutska kombinacija etinilestradiola i drospirenona za primenu kao kontraceptivnog sredstva |
| ATE442147T1 (de) * | 2000-01-18 | 2009-09-15 | Bayer Schering Pharma Ag | Pharmazeutische zubereitung enthaltend drospirenon |
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| EP1260225A1 (en) * | 2001-05-18 | 2002-11-27 | Pantarhei Bioscience B.V. | A pharmaceutical composition for use in hormone replacement therapy |
| EP1551415B1 (en) * | 2002-09-05 | 2009-12-23 | Pantarhei Bioscience B.V. | Oral pharmaceutical composition comprising 15-hydroxytestosterone and its analogues |
| DE60330888D1 (de) * | 2002-11-05 | 2010-02-25 | Bayer Schering Pharma Ag | Verwendung von drospirenon zur behandlung von hypertension |
-
2005
- 2005-03-10 ES ES05708751T patent/ES2325591T3/es not_active Expired - Lifetime
- 2005-03-10 SI SI200530738T patent/SI1748756T1/sl unknown
- 2005-03-10 JP JP2007502436A patent/JP2007528388A/ja active Pending
- 2005-03-10 EA EA200601570A patent/EA012570B1/ru not_active IP Right Cessation
- 2005-03-10 HR HR20090381T patent/HRP20090381T1/xx unknown
- 2005-03-10 EP EP05708751A patent/EP1748756B1/en not_active Revoked
- 2005-03-10 AU AU2005221402A patent/AU2005221402B2/en not_active Ceased
- 2005-03-10 NZ NZ549792A patent/NZ549792A/en unknown
- 2005-03-10 BR BRPI0508612-4A patent/BRPI0508612A/pt not_active IP Right Cessation
- 2005-03-10 DE DE602005014227T patent/DE602005014227D1/de not_active Revoked
- 2005-03-10 CA CA002558393A patent/CA2558393A1/en not_active Abandoned
- 2005-03-10 PL PL05708751T patent/PL1748756T3/pl unknown
- 2005-03-10 EP EP08011577A patent/EP1980242B1/en not_active Expired - Lifetime
- 2005-03-10 PT PT05708751T patent/PT1748756E/pt unknown
- 2005-03-10 DK DK05708751T patent/DK1748756T3/da active
- 2005-03-10 AT AT05708751T patent/ATE429900T1/de not_active IP Right Cessation
- 2005-03-10 KR KR1020067020960A patent/KR20060130723A/ko not_active Ceased
- 2005-03-10 WO PCT/IB2005/000665 patent/WO2005087194A1/en not_active Ceased
- 2005-03-10 AT AT08011577T patent/ATE476961T1/de not_active IP Right Cessation
-
2006
- 2006-09-05 IL IL177893A patent/IL177893A0/en unknown
- 2006-09-07 CU CU20060173A patent/CU20060173A7/es unknown
- 2006-09-14 CR CR8631A patent/CR8631A/es not_active Application Discontinuation
- 2006-10-02 EC EC2006006901A patent/ECSP066901A/es unknown
-
2009
- 2009-07-28 CY CY20091100805T patent/CY1109265T1/el unknown
- 2009-11-25 AU AU2009240844A patent/AU2009240844A1/en not_active Abandoned
-
2010
- 2010-03-24 JP JP2010068645A patent/JP2010150289A/ja active Pending
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