JP2007526336A5 - - Google Patents
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- Publication number
- JP2007526336A5 JP2007526336A5 JP2007502061A JP2007502061A JP2007526336A5 JP 2007526336 A5 JP2007526336 A5 JP 2007526336A5 JP 2007502061 A JP2007502061 A JP 2007502061A JP 2007502061 A JP2007502061 A JP 2007502061A JP 2007526336 A5 JP2007526336 A5 JP 2007526336A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- trifluoromethyl
- cyano
- trifluoroethyl
- cyclopropylmethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54979404P | 2004-03-03 | 2004-03-03 | |
| US60/549,794 | 2004-03-03 | ||
| PCT/US2005/007245 WO2005085185A1 (en) | 2004-03-03 | 2005-03-03 | Aniline derivatives as selective androgen receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007526336A JP2007526336A (ja) | 2007-09-13 |
| JP2007526336A5 true JP2007526336A5 (enExample) | 2008-04-17 |
| JP4805909B2 JP4805909B2 (ja) | 2011-11-02 |
Family
ID=34919539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502061A Expired - Lifetime JP4805909B2 (ja) | 2004-03-03 | 2005-03-03 | 選択的アンドロゲン受容体モジュレーターとしてのアニリン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7514470B2 (enExample) |
| EP (1) | EP1725522B1 (enExample) |
| JP (1) | JP4805909B2 (enExample) |
| ES (1) | ES2523017T3 (enExample) |
| WO (1) | WO2005085185A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004110978A2 (en) * | 2003-06-10 | 2004-12-23 | Smithkline Beecham Corporation | 1-aminonaphthalenes as modulators of androgen, glucocorticoid, mineralocorticoid and progesterone receptors |
| WO2005000795A2 (en) * | 2003-06-10 | 2005-01-06 | Smithkline Beecham Corporation | Aniline derivatived androgen-, glucocorticoid-, mineralcorticoid- and progesterone- receptor modulators |
| JP2008536868A (ja) * | 2005-04-15 | 2008-09-11 | スミスクライン・ビーチャム・コーポレイション | シアノアリールアミン |
| WO2007065093A2 (en) * | 2005-11-30 | 2007-06-07 | Smithkline Beecham Corporation | Pyrrolidineanilines |
| JP5102985B2 (ja) * | 2006-07-18 | 2012-12-19 | 東ソ−・エフテック株式会社 | 含フッ素２級アミン化合物の製造方法 |
| AU2007284161A1 (en) * | 2006-08-09 | 2008-02-21 | Smithkline Beecham Corporation | Pyrrolidinone anilines as progesterone receptor modulators |
| JP5204438B2 (ja) * | 2007-07-31 | 2013-06-05 | 東ソ−・エフテック株式会社 | 含フッ素アミン化合物の製造方法 |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| BRPI0907844B8 (pt) | 2008-02-22 | 2021-05-25 | Radius Health Inc | compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos |
| NZ588737A (en) * | 2008-03-31 | 2012-05-25 | Univ Columbia | Methods of diagnosing, preventing and treating bone mass diseases |
| WO2009136629A1 (ja) * | 2008-05-09 | 2009-11-12 | あすか製薬株式会社 | 生活習慣病予防・治療剤 |
| AT509045B1 (de) | 2010-01-29 | 2011-06-15 | Planta Naturstoffe Vertriebsges M B H | Verbindungen zur behandlung von asthma bronchiale |
| JP5964756B2 (ja) | 2010-02-04 | 2016-08-03 | ラジウス ヘルス，インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
| PL2568806T3 (pl) | 2010-05-12 | 2017-03-31 | Radius Health, Inc. | Schematy lecznicze |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| AU2011312490B2 (en) | 2010-09-28 | 2015-06-25 | Radius Pharmaceuticals, Inc. | Selective androgen receptor modulators |
| ES2939940T3 (es) | 2014-03-28 | 2023-04-28 | Univ Duke | Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| KR20190077607A (ko) * | 2014-10-16 | 2019-07-03 | 지티엑스, 인코포레이티드 | Sarm을 이용하는 비뇨기 장애의 치료 방법 |
| WO2017223115A1 (en) | 2016-06-22 | 2017-12-28 | Radius Health, Inc. | Ar+ breast cancer treatment methods |
| EP3565542B1 (en) | 2017-01-05 | 2024-04-10 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
| BR112020023136A2 (pt) | 2018-05-14 | 2021-02-09 | Nuvation Bio Inc. | compostos de alvo de receptor de hormônio nuclear anticâncer |
| SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
| US12441745B2 (en) | 2019-02-12 | 2025-10-14 | Radius Pharmaceuticals, Inc. | Processes and compounds |
| CN113811333B (zh) | 2019-05-14 | 2024-03-12 | 诺维逊生物股份有限公司 | 靶向抗癌核激素受体的化合物 |
| EP4058464A1 (en) | 2019-11-13 | 2022-09-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| EP4313991A1 (en) | 2021-03-23 | 2024-02-07 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| WO2022235585A1 (en) | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5585198A (en) | 1996-11-22 | 1998-06-10 | Athena Pharmaceuticals, Inc. | N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions, and ethods for inhibiting beta-amyloid peptide release and/or its synthesis |
| AU5354398A (en) | 1996-11-22 | 1998-06-10 | Elan Pharmaceuticals, Inc. | N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions compri sing same, and methods for inhibiting beta-amyloid peptide release and/or it s synthesis by use of such compounds |
| US6569896B2 (en) * | 2000-08-24 | 2003-05-27 | The University Of Tennessee Research Corporation | Selective androgen receptor modulators and methods of use thereof |
| US6506782B1 (en) * | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| ATE301642T1 (de) * | 2000-06-06 | 2005-08-15 | Warner Lambert Co | Bicyclische cyclohexylamine und ihre verwendung als nmda-rezeptor antagonisten |
| CN1176905C (zh) * | 2002-03-22 | 2004-11-24 | 清华大学 | 甘氨酸乙酯邻苯二腈及其合成方法与应用 |
| WO2005000795A2 (en) * | 2003-06-10 | 2005-01-06 | Smithkline Beecham Corporation | Aniline derivatived androgen-, glucocorticoid-, mineralcorticoid- and progesterone- receptor modulators |
-
2005
- 2005-03-03 ES ES05730067.5T patent/ES2523017T3/es not_active Expired - Lifetime
- 2005-03-03 US US10/598,508 patent/US7514470B2/en not_active Expired - Lifetime
- 2005-03-03 EP EP05730067.5A patent/EP1725522B1/en not_active Expired - Lifetime
- 2005-03-03 JP JP2007502061A patent/JP4805909B2/ja not_active Expired - Lifetime
- 2005-03-03 WO PCT/US2005/007245 patent/WO2005085185A1/en not_active Ceased
-
2009
- 2009-02-25 US US12/392,687 patent/US7723385B2/en not_active Expired - Lifetime