JP2007523192A - 広域スペクトラム抗癌剤としてのβ−ラパコンの使用 - Google Patents

広域スペクトラム抗癌剤としてのβ−ラパコンの使用 Download PDF

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Publication number
JP2007523192A
JP2007523192A JP2006554304A JP2006554304A JP2007523192A JP 2007523192 A JP2007523192 A JP 2007523192A JP 2006554304 A JP2006554304 A JP 2006554304A JP 2006554304 A JP2006554304 A JP 2006554304A JP 2007523192 A JP2007523192 A JP 2007523192A
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Japan
Prior art keywords
cancer
lapachone
pharmaceutically acceptable
acceptable salt
anal
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JP2006554304A
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English (en)
Japanese (ja)
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JP2007523192A5 (https=
Inventor
リ・チャン・ジェイ
リ・ヨウチ
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アークル・インコーポレーテツド
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Publication of JP2007523192A publication Critical patent/JP2007523192A/ja
Publication of JP2007523192A5 publication Critical patent/JP2007523192A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
JP2006554304A 2004-02-20 2005-02-18 広域スペクトラム抗癌剤としてのβ−ラパコンの使用 Withdrawn JP2007523192A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54591604P 2004-02-20 2004-02-20
PCT/US2005/005647 WO2005082358A2 (en) 2004-02-20 2005-02-18 Use of beta-lapachone as a broad spectrum anti-cancer agent

Publications (2)

Publication Number Publication Date
JP2007523192A true JP2007523192A (ja) 2007-08-16
JP2007523192A5 JP2007523192A5 (https=) 2008-03-27

Family

ID=34910740

Family Applications (1)

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JP2006554304A Withdrawn JP2007523192A (ja) 2004-02-20 2005-02-18 広域スペクトラム抗癌剤としてのβ−ラパコンの使用

Country Status (4)

Country Link
EP (1) EP1722776A2 (https=)
JP (1) JP2007523192A (https=)
CA (1) CA2556794A1 (https=)
WO (1) WO2005082358A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007523187A (ja) * 2004-02-20 2007-08-16 アルキュール， インコーポレイテッド 癌を処置または予防するためのβ−ラパコンの使用
JP2011507949A (ja) * 2007-12-28 2011-03-10 マゼンス インコーポレイテッド 腎臓病を処置及び予防するための薬学的組成物
WO2013153821A1 (ja) * 2012-04-12 2013-10-17 Omura Satoshi Ｐｄｋ４阻害剤及びその利用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101119726B (zh) * 2005-02-16 2011-02-02 麦仁斯有限公司 用于治疗或预防涉及肥胖、糖尿病、代谢综合症、神经变性疾病和线粒体功能障碍疾病的疾病的药物组合物
JP7411875B2 (ja) * 2020-10-08 2024-01-12 株式会社 キュロム・バイオサイエンス ベータ－ラパコンを有効成分として含む胆汁うっ滞性肝疾患予防又は治療用薬学組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763625A (en) * 1995-04-25 1998-06-09 Wisconsin Alumni Research Foundation Synthesis and use of β-lapachone analogs
US5883270A (en) * 1996-02-20 1999-03-16 Wisconsin Alumni Research Foundation 4-substituted-1, 2-naphthoquinones and their use in the inhibition of neoplastic cell growth
AU2003254029A1 (en) * 2002-07-17 2004-02-02 Arqule, Inc. Activated checkpoint therapy and methods of use thereof
BR0316296A (pt) * 2002-11-18 2005-12-13 Arqule Inc Compostos lapacone e seus métodos de uso
WO2004050033A2 (en) * 2002-12-02 2004-06-17 Arqule, Inc. Method of treating cancers

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007523187A (ja) * 2004-02-20 2007-08-16 アルキュール， インコーポレイテッド 癌を処置または予防するためのβ−ラパコンの使用
JP2011507949A (ja) * 2007-12-28 2011-03-10 マゼンス インコーポレイテッド 腎臓病を処置及び予防するための薬学的組成物
WO2013153821A1 (ja) * 2012-04-12 2013-10-17 Omura Satoshi Ｐｄｋ４阻害剤及びその利用

Also Published As

Publication number Publication date
EP1722776A2 (en) 2006-11-22
WO2005082358A2 (en) 2005-09-09
CA2556794A1 (en) 2005-09-09
WO2005082358A3 (en) 2005-12-15

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