JP2007523135A5 - - Google Patents
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- Publication number
- JP2007523135A5 JP2007523135A5 JP2006553623A JP2006553623A JP2007523135A5 JP 2007523135 A5 JP2007523135 A5 JP 2007523135A5 JP 2006553623 A JP2006553623 A JP 2006553623A JP 2006553623 A JP2006553623 A JP 2006553623A JP 2007523135 A5 JP2007523135 A5 JP 2007523135A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- dementia
- korsakov
- parkinson
- alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010012289 Dementia Diseases 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 208000028698 Cognitive impairment Diseases 0.000 claims 2
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 2
- 208000018737 Parkinson disease Diseases 0.000 claims 2
- 208000000609 Pick Disease of the Brain Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 208000010877 cognitive disease Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002739 subcortical effect Effects 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0401690A FR2866647B1 (fr) | 2004-02-20 | 2004-02-20 | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2005/000382 WO2005089747A1 (fr) | 2004-02-20 | 2005-02-18 | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007523135A JP2007523135A (ja) | 2007-08-16 |
| JP2007523135A5 true JP2007523135A5 (https=) | 2010-05-20 |
| JP4519861B2 JP4519861B2 (ja) | 2010-08-04 |
Family
ID=34833930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553623A Expired - Fee Related JP4519861B2 (ja) | 2004-02-20 | 2005-02-18 | 新規なアザ二環式誘導体、その製造方法、およびそれを含む医薬組成物 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7576120B2 (https=) |
| EP (1) | EP1720544B1 (https=) |
| JP (1) | JP4519861B2 (https=) |
| KR (1) | KR100885104B1 (https=) |
| CN (2) | CN100577160C (https=) |
| AR (3) | AR047685A1 (https=) |
| AT (1) | ATE389398T1 (https=) |
| AU (1) | AU2005224129B2 (https=) |
| BR (1) | BRPI0507830A (https=) |
| CA (1) | CA2555216C (https=) |
| CY (1) | CY1108529T1 (https=) |
| DE (1) | DE602005005456T2 (https=) |
| DK (1) | DK1720544T3 (https=) |
| EA (1) | EA010300B1 (https=) |
| ES (1) | ES2303233T3 (https=) |
| FR (1) | FR2866647B1 (https=) |
| GE (1) | GEP20094578B (https=) |
| HR (1) | HRP20080184T5 (https=) |
| MA (1) | MA28342A1 (https=) |
| ME (1) | ME01400B (https=) |
| MY (1) | MY137282A (https=) |
| NO (1) | NO337013B1 (https=) |
| NZ (1) | NZ548898A (https=) |
| PL (1) | PL1720544T3 (https=) |
| PT (1) | PT1720544E (https=) |
| RS (1) | RS50577B (https=) |
| SI (1) | SI1720544T1 (https=) |
| WO (1) | WO2005089747A1 (https=) |
| ZA (1) | ZA200606558B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1717235A3 (en) * | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| EP1717234A1 (en) * | 2005-04-29 | 2006-11-02 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| US20090023731A1 (en) * | 2007-03-22 | 2009-01-22 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors |
| FR2932479A1 (fr) * | 2008-06-13 | 2009-12-18 | Servier Lab | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2937251B1 (fr) * | 2008-10-16 | 2011-03-18 | Servier Lab | Utilisation du 4-{3-°hexahydrocyclopenta°c!pyrrol-2(1h)-yl! propoxy}benzamide pour l'obtention de medicaments destines au traitement des troubles du sommeil |
| FR2953513B1 (fr) | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives azabicyclo[3.2.0]hept-6-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2953514B1 (fr) | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2953515B1 (fr) | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives du type hexahydrocyclopenta[b]pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2953521B1 (fr) * | 2009-12-09 | 2011-11-18 | Servier Lab | Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2974729B1 (fr) | 2011-05-02 | 2013-04-19 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide et un inhibiteur de l'acetylcholinesterase et les compositions pharmaceutiques qui la contiennent |
| FR2976285B1 (fr) * | 2011-06-08 | 2013-05-24 | Servier Lab | Procede de synthese et forme cristalline du chlorhydrate de 4-{3-[cis-hexahydrocypenta[c]pyrrol-2(1h)-yl]propoxy}benzamide ainsi que les compositions pharmaceutiques qui la contiennent |
| FR2976286B1 (fr) * | 2011-06-08 | 2013-05-24 | Servier Lab | 4-{3-[trans-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
| EP2789608A4 (en) | 2011-12-08 | 2015-07-01 | Taisho Pharmaceutical Co Ltd | PHENYLPYRROLDERIVAT |
| FR2983732B1 (fr) | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
| TW201343636A (zh) * | 2011-12-27 | 2013-11-01 | 大正製藥股份有限公司 | 苯基三唑衍生物 |
| CN103183632A (zh) * | 2011-12-29 | 2013-07-03 | 山东方明药业集团股份有限公司 | 一种3-氮杂双环辛烷盐酸盐的提纯方法 |
| FR2999179A1 (fr) * | 2012-12-07 | 2014-06-13 | Servier Lab | Procede de synthese d'un sel d'addition a un acide pharmaceutiquement acceptable du 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide, ainsi que les formes cristallines associees |
| FR3003466B1 (fr) * | 2013-03-22 | 2015-08-07 | Servier Lab | Utilisation du 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide pour le traitement des douleurs neuropathiques |
| EP3594206A1 (en) * | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-quinoline derivatives for treating a rna virus infection |
| EP3594205A1 (en) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-aryl derivatives for treating a rna virus infection |
| CN111377846B (zh) * | 2018-12-27 | 2022-05-24 | 江苏恩华药业股份有限公司 | 一种哌嗪苯甲酰胺类衍生物及其应用 |
| CN111377911B (zh) * | 2018-12-27 | 2022-05-24 | 江苏恩华药业股份有限公司 | 一种吗啉苯甲酰胺类化合物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2962496A (en) * | 1957-01-28 | 1960-11-29 | Geschickter Fund Med Res | Nu-substituted-3-azabicyclooctanes [3: 3: 0] and salts thereof |
| DE4341403A1 (de) * | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
| EP1299352B1 (en) * | 2000-06-30 | 2005-12-28 | Elan Pharmaceuticals, Inc. | Compounds to treat alzheimer's disease |
| BR0108088A (pt) * | 2000-07-13 | 2004-04-06 | Abbott Lab | Pirrolidinas 1,3-dissubstituìdas e 1,3,3-trissubstituìdas como ligandos receptores de histamina-3 e suas aplicações terapêuticas |
| FR2827288B1 (fr) * | 2001-07-12 | 2003-10-31 | Servier Lab | Nouveaux derives d'octahydro-2h-pyrido[1,2-a]pyrazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2004
- 2004-02-20 FR FR0401690A patent/FR2866647B1/fr not_active Expired - Fee Related
-
2005
- 2005-02-18 CN CN200580005456A patent/CN100577160C/zh not_active Expired - Fee Related
- 2005-02-18 CA CA2555216A patent/CA2555216C/fr not_active Expired - Fee Related
- 2005-02-18 JP JP2006553623A patent/JP4519861B2/ja not_active Expired - Fee Related
- 2005-02-18 KR KR1020067019301A patent/KR100885104B1/ko not_active Expired - Fee Related
- 2005-02-18 EP EP05717646A patent/EP1720544B1/fr not_active Expired - Lifetime
- 2005-02-18 DK DK05717646T patent/DK1720544T3/da active
- 2005-02-18 ME MEP-2008-947A patent/ME01400B/me unknown
- 2005-02-18 AT AT05717646T patent/ATE389398T1/de active
- 2005-02-18 CN CN2008100828098A patent/CN101230033B/zh not_active Expired - Fee Related
- 2005-02-18 MY MYPI20050619A patent/MY137282A/en unknown
- 2005-02-18 BR BRPI0507830-0A patent/BRPI0507830A/pt not_active IP Right Cessation
- 2005-02-18 NZ NZ548898A patent/NZ548898A/en not_active IP Right Cessation
- 2005-02-18 RS RSP-2008/0226A patent/RS50577B/sr unknown
- 2005-02-18 DE DE602005005456T patent/DE602005005456T2/de not_active Expired - Lifetime
- 2005-02-18 EA EA200601512A patent/EA010300B1/ru not_active IP Right Cessation
- 2005-02-18 GE GEAP20059627A patent/GEP20094578B/en unknown
- 2005-02-18 HR HR20080184T patent/HRP20080184T5/xx unknown
- 2005-02-18 AU AU2005224129A patent/AU2005224129B2/en not_active Ceased
- 2005-02-18 ES ES05717646T patent/ES2303233T3/es not_active Expired - Lifetime
- 2005-02-18 PL PL05717646T patent/PL1720544T3/pl unknown
- 2005-02-18 PT PT05717646T patent/PT1720544E/pt unknown
- 2005-02-18 AR ARP050100585A patent/AR047685A1/es active IP Right Grant
- 2005-02-18 SI SI200530217T patent/SI1720544T1/sl unknown
- 2005-02-18 WO PCT/FR2005/000382 patent/WO2005089747A1/fr not_active Ceased
- 2005-02-20 US US10/589,831 patent/US7576120B2/en not_active Expired - Fee Related
-
2006
- 2006-08-03 MA MA29229A patent/MA28342A1/fr unknown
- 2006-08-07 ZA ZA2006/06558A patent/ZA200606558B/en unknown
- 2006-09-14 NO NO20064160A patent/NO337013B1/no not_active IP Right Cessation
-
2008
- 2008-05-20 CY CY20081100520T patent/CY1108529T1/el unknown
-
2012
- 2012-12-26 AR ARP120104964A patent/AR089451A2/es unknown
-
2014
- 2014-01-28 AR ARP140100250A patent/AR094601A2/es unknown
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