JP2007523089A5 - - Google Patents
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- JP2007523089A5 JP2007523089A5 JP2006553342A JP2006553342A JP2007523089A5 JP 2007523089 A5 JP2007523089 A5 JP 2007523089A5 JP 2006553342 A JP2006553342 A JP 2006553342A JP 2006553342 A JP2006553342 A JP 2006553342A JP 2007523089 A5 JP2007523089 A5 JP 2007523089A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- nucleic acid
- binding
- antagonist
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54573004P | 2004-02-17 | 2004-02-17 | |
| US60/545,730 | 2004-02-17 | ||
| PCT/US2005/004743 WO2005079844A2 (en) | 2004-02-17 | 2005-02-15 | Use for interleukin-33 (il33) and the il-33 receptor complex |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011131646A Division JP2011178810A (ja) | 2004-02-17 | 2011-06-13 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007523089A JP2007523089A (ja) | 2007-08-16 |
| JP2007523089A5 true JP2007523089A5 (https=) | 2008-03-21 |
| JP4949859B2 JP4949859B2 (ja) | 2012-06-13 |
Family
ID=34886190
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553342A Expired - Lifetime JP4949859B2 (ja) | 2004-02-17 | 2005-02-15 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
| JP2011131646A Pending JP2011178810A (ja) | 2004-02-17 | 2011-06-13 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
| JP2014030239A Pending JP2014098026A (ja) | 2004-02-17 | 2014-02-20 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
| JP2015163939A Pending JP2016034948A (ja) | 2004-02-17 | 2015-08-21 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011131646A Pending JP2011178810A (ja) | 2004-02-17 | 2011-06-13 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
| JP2014030239A Pending JP2014098026A (ja) | 2004-02-17 | 2014-02-20 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
| JP2015163939A Pending JP2016034948A (ja) | 2004-02-17 | 2015-08-21 | インターロイキン−33(il33)およびil−33レセプター複合体の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US20050203046A1 (https=) |
| EP (2) | EP2283860A3 (https=) |
| JP (4) | JP4949859B2 (https=) |
| CN (1) | CN1917902A (https=) |
| AT (1) | ATE496636T1 (https=) |
| AU (1) | AU2005215528B2 (https=) |
| BR (1) | BRPI0507808A (https=) |
| CA (1) | CA2555236C (https=) |
| DE (1) | DE602005026105D1 (https=) |
| NO (1) | NO20064193L (https=) |
| NZ (1) | NZ549040A (https=) |
| TW (2) | TW201304802A (https=) |
| WO (1) | WO2005079844A2 (https=) |
| ZA (1) | ZA200606844B (https=) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038794A2 (en) | 2000-11-09 | 2002-05-16 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| DK3072978T3 (en) | 2002-05-09 | 2018-09-17 | Brigham & Womens Hospital Inc | : 1L1RL-1 AS A CARDIOVASCULAR DISEASE MARKER |
| NZ549040A (en) * | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
| US20120144504A1 (en) * | 2005-10-16 | 2012-06-07 | Yeda Research And Development Co. Ltd. | Caspase-8 and skin disease |
| AU2007244927B2 (en) * | 2006-04-24 | 2012-01-12 | Critical Care Diagnostics, Inc. | Predicting mortality and detecting severe disease |
| ATE517341T1 (de) * | 2006-04-27 | 2011-08-15 | Critical Care Diagnostics Inc | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
| EP2021796B1 (en) * | 2006-05-01 | 2012-02-08 | Critical Care Diagnostics, Inc. | Diagnosis of cardiovascular disease |
| PL2019965T3 (pl) * | 2006-05-02 | 2015-10-30 | Critical Care Diagnostics Inc | Rozpoznawanie różnicowe chorób układu oddechowego i sercowo-naczyniowego |
| US8147817B2 (en) * | 2006-05-04 | 2012-04-03 | The Brigham And Women's Hospital, Inc. | IL-33 in the treatment and diagnosis of diseases and disorders |
| US7560530B1 (en) | 2006-07-20 | 2009-07-14 | Schering Corporation | IL-33 receptor |
| SE532250C2 (sv) * | 2006-11-28 | 2009-11-24 | Theravac Pharmaceuticals Ab | Nya formuleringar av IL-33 för behandling av inflammatoriska tillstånd med en stark TH2 komponent genom vaccinering |
| IE20080331A1 (en) * | 2007-04-26 | 2009-07-08 | Trinity College Dublin | Products for altering cytokine activity and methods therefor |
| AU2008254704A1 (en) * | 2007-05-18 | 2008-11-27 | Medimmune, Llc | IL-33 in inflammatory disease |
| PL2269063T3 (pl) | 2008-04-18 | 2014-04-30 | Critical Care Diagnostics Inc | Rokowanie ryzyka głównych niekorzystnych zdarzeń sercowych |
| JP5539660B2 (ja) * | 2009-03-10 | 2014-07-02 | 公益財団法人ヒューマンサイエンス振興財団 | 粘膜ワクチン用アジュバント |
| WO2011031600A1 (en) * | 2009-09-10 | 2011-03-17 | Schering Corporation | Use of il-33 antagonists to treat fibrotic disease |
| WO2012113813A1 (en) * | 2011-02-23 | 2012-08-30 | F. Hoffmann-La Roche Ag | Antibodies against human il33r and uses thereof |
| FR2972006B1 (fr) | 2011-02-24 | 2016-03-25 | Centre Nat Rech Scient | Nouveaux fragments d'il-33 superactifs et leurs utilisations |
| ES2750126T3 (es) | 2011-03-17 | 2020-03-25 | Critical Care Diagnostics Inc | Procedimientos de predicción del riesgo de un resultado clínico adverso |
| US9090694B2 (en) | 2012-04-30 | 2015-07-28 | Janssen Biotech, Inc. | ST2L antibody antagonists |
| AR091069A1 (es) | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
| CN104737170A (zh) | 2012-08-21 | 2015-06-24 | 重症监护诊断股份有限公司 | 多标记风险分层 |
| AU2013357427B2 (en) * | 2012-12-10 | 2017-08-31 | Universiteit Gent | Novel Interleukin-33 inhibitors |
| WO2014126277A1 (ko) * | 2013-02-14 | 2014-08-21 | 건국대학교 산학협력단 | 신규한 인터루킨-33 수용체와 결합 단백질 조성물 및 그 용도 |
| EP2958583B1 (en) | 2013-02-22 | 2018-04-11 | Magic Epoch Holdings Limited | Il-33 and treatment of neurodegenerative diseases |
| JO3532B1 (ar) | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
| CN105246490A (zh) * | 2013-03-15 | 2016-01-13 | 伊利克斯根公司 | 使用zscan4复壮人细胞的方法 |
| WO2014152195A1 (en) * | 2013-03-15 | 2014-09-25 | Regeneron Pharmaceuticals, Inc. | Il-33 antagonists and uses thereof |
| EP3047024B1 (en) * | 2013-09-20 | 2019-04-24 | University Of Virginia Patent Foundation | Compositions and methods for treatment of autoimmune and inflammatory diseases and disorders |
| WO2015054012A1 (en) * | 2013-10-07 | 2015-04-16 | The Trustees Of The University Of Pennsylvania | Vaccines with interleukin-33 as an adjuvant |
| BR112016013347B1 (pt) * | 2013-12-26 | 2023-12-12 | Mitsubishi Tanabe Pharma Corporation | Anticorpo monoclonal humano neutralizante anti-il-33, composição farmacêutica, inibidor da expressão de citocinas, molécula de ácido nucleico, vetor, célula bacteriana transgênica, método de produção e uso dos mesmos |
| SG11201605580RA (en) * | 2014-01-10 | 2016-10-28 | Anaptysbio Inc | Antibodies directed against interleukin-33 (il-33) |
| WO2015143343A2 (en) | 2014-03-21 | 2015-09-24 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treatment of immune-related diseases or disorders and/or therapy monitoring |
| EP3134120B1 (en) | 2014-04-21 | 2024-01-24 | The Children's Hospital of Philadelphia | Compositions and methods for treating cytokine-related disorders |
| CN107109494B (zh) * | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| TWI705976B (zh) | 2014-11-10 | 2020-10-01 | 美商建南德克公司 | 抗介白素-33抗體及其用途 |
| EP3265107B1 (en) | 2015-03-02 | 2024-10-02 | 180 Therapeutics LP | Method of treating a localized fibrotic disorder using a tnf receptor 2 antagonist |
| JP6991863B2 (ja) * | 2015-03-03 | 2022-02-03 | カヴァ ヘルスケア インコーポレイテッド | 2型自然リンパ球細胞、インターロイキン33、及び/またはインターフェロン誘導性タンパク質44による癌免疫の調節 |
| KR102261618B1 (ko) | 2015-03-31 | 2021-06-04 | 메디뮨 리미티드 | 신규한 il33 형태, il33의 돌연변이된 형태, 항체, 검정 및 이의 이용 방법 |
| JP6501650B2 (ja) * | 2015-06-25 | 2019-04-17 | 田辺三菱製薬株式会社 | ヒト抗il−33中和モノクローナル抗体 |
| WO2017009750A1 (en) * | 2015-07-10 | 2017-01-19 | The Hong Kong University Of Science And Technology | Methods and compositions for treating neurodegenerative and neuroinflammatory conditions |
| EA201890891A1 (ru) * | 2015-10-06 | 2018-09-28 | Ридженерон Фармасьютикалз, Инк. | Биомаркеры, связанные с заболеваниями, опосредованными интерлейкином-33 (ил-33), и их применение |
| KR101765397B1 (ko) | 2015-12-02 | 2017-08-07 | 한국과학기술원 | 질점막을 통한 바이러스 감염 취약 진단 마커로서의 il-33의 용도 |
| JP2019516362A (ja) | 2016-04-27 | 2019-06-20 | ファイザー・インク | 抗il−33抗体、その組成物、方法および使用 |
| FI3478723T3 (fi) | 2016-06-29 | 2026-03-17 | Checkpoint Therapeutics Inc | Pd-l1-spesifisiä vasta-aineita ja niiden käyttömenetelmiä |
| JOP20190093A1 (ar) * | 2016-10-28 | 2019-04-25 | Lilly Co Eli | أجسام مضادة لـ il-33 واستخداماتها |
| TWI857389B (zh) | 2016-12-01 | 2024-10-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| PE20191548A1 (es) | 2017-02-10 | 2019-10-24 | Genentech Inc | Anticuerpos contra triptasa, composiciones de estos y usos de estos |
| US20200339674A1 (en) * | 2017-02-17 | 2020-10-29 | The General Hospital Corporation | Methods and compositions for treating a brain injury |
| ES3052989T3 (en) | 2017-04-13 | 2026-01-16 | Regeneron Pharma | Treatment and inhibition of inflammatory lung diseases in patients having risk alleles in the genes encoding il33 and il1rl1 |
| ES2945740T3 (es) | 2017-05-05 | 2023-07-06 | Univ Pittsburgh Commonwealth Sys Higher Education | Aplicaciones oculares de vesículas unidas a matriz (MBV) |
| MY199245A (en) | 2017-08-31 | 2023-10-23 | Hyogo College Medicine | Il-33 antagonist-containing therapeutic agent for endometriosis |
| AU2019218128A1 (en) | 2018-02-09 | 2020-09-17 | Genentech, Inc. | Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases |
| IL307286B2 (en) | 2018-04-11 | 2026-03-01 | Regeneron Pharma | Methods and reagents for IL-33 quantification |
| CN112805016A (zh) * | 2018-05-03 | 2021-05-14 | 联邦高等教育系统匹兹堡大学 | 包含il-33的基质结合囊泡(mbv)及其用途 |
| US11401324B2 (en) | 2018-08-30 | 2022-08-02 | HCW Biologics, Inc. | Single-chain chimeric polypeptides and uses thereof |
| US11518792B2 (en) | 2018-08-30 | 2022-12-06 | HCW Biologics, Inc. | Multi-chain chimeric polypeptides and uses thereof |
| CA3109361A1 (en) | 2018-08-30 | 2020-03-05 | HCW Biologics, Inc. | Single-chain and multi-chain chimeric polypeptides and uses thereof |
| TW202519263A (zh) | 2019-03-21 | 2025-05-16 | 美商再生元醫藥公司 | 含有抗il-33抗體之穩定調配物 |
| CN120924491A (zh) | 2019-06-21 | 2025-11-11 | 免疫生物公司 | 多链嵌合多肽和其用途 |
| EP3989985A4 (en) * | 2019-06-30 | 2023-09-13 | Memorial Sloan Kettering Cancer Center | METHODS AND COMPOSITIONS FOR TREATING PANCREATIC CANCER |
| US20230101029A1 (en) * | 2019-10-11 | 2023-03-30 | General Regeneratives (Shanghai) Limited | Methods of using il-33 protein in treating cancers |
| IL292443A (en) * | 2019-11-04 | 2022-06-01 | Medimmune Ltd | Methods for using IL-33 antagonists |
| WO2021163299A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Chromatography resin and uses thereof |
| AU2021220870A1 (en) | 2020-02-11 | 2022-08-04 | Immunitybio, Inc. | Methods of treating age-related and inflammatory diseases |
| CA3169243A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Methods of activating regulatory t cells |
| AU2021236306A1 (en) | 2020-03-13 | 2022-09-15 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN115836087A (zh) | 2020-04-29 | 2023-03-21 | Hcw生物科技公司 | 抗cd26蛋白及其用途 |
| WO2021247003A1 (en) | 2020-06-01 | 2021-12-09 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| US12024545B2 (en) | 2020-06-01 | 2024-07-02 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| JP2023527869A (ja) | 2020-06-01 | 2023-06-30 | エイチシーダブリュー バイオロジックス インコーポレイテッド | 加齢関連障害の治療法 |
| CN112210556A (zh) * | 2020-10-15 | 2021-01-12 | 扬州大学 | 一组靶向干扰IL-33表达的shRNA、重组腺病毒载体及其构建方法和应用 |
| EP4430072A1 (en) | 2021-11-10 | 2024-09-18 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN114426981B (zh) * | 2022-02-21 | 2022-11-29 | 吉林农业大学 | 非洲猪瘟病毒抗原蛋白重组表达载体、重组植物乳酸菌及其制备方法和应用 |
| WO2023201311A1 (en) | 2022-04-13 | 2023-10-19 | HCW Biologics, Inc. | Multi-chain chimeric polypeptide for use in the treatment of treating neuroinflammatory disorder |
| CN118185884A (zh) * | 2023-10-16 | 2024-06-14 | 王琪 | 负载il33的溶瘤痘苗病毒及其与免疫检查点抑制剂的联合疗法 |
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| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US6176962B1 (en) | 1990-02-28 | 2001-01-23 | Aclara Biosciences, Inc. | Methods for fabricating enclosed microchannel structures |
| WO1992010210A1 (en) * | 1990-12-14 | 1992-06-25 | E.I. Du Pont De Nemours And Company | Inhibition of angiogenesis by il-1 |
| US5571702A (en) | 1991-03-29 | 1996-11-05 | Genentech, Inc. | Amplification method for detection of human PF4A receptors |
| WO1995001997A1 (en) | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| US5576191A (en) * | 1994-06-17 | 1996-11-19 | Immunex Corporation | Cytokine that binds ST2 |
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| WO2001046697A2 (en) | 1999-12-21 | 2001-06-28 | Millennium Predictive Medicine | Identification, assessment, prevention, and therapy of breast cancer |
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| JP2007537717A (ja) | 2004-01-07 | 2007-12-27 | ブリストル−マイヤーズ スクイブ カンパニー | 上皮増殖因子受容体モデュレーターに対する感受性を決定するためのバイオマーカーおよび方法 |
| NZ549040A (en) | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
| US7560530B1 (en) | 2006-07-20 | 2009-07-14 | Schering Corporation | IL-33 receptor |
| AU2008254704A1 (en) | 2007-05-18 | 2008-11-27 | Medimmune, Llc | IL-33 in inflammatory disease |
-
2004
- 2004-11-29 NZ NZ549040A patent/NZ549040A/xx not_active IP Right Cessation
-
2005
- 2005-02-15 EP EP10177117.8A patent/EP2283860A3/en not_active Withdrawn
- 2005-02-15 AU AU2005215528A patent/AU2005215528B2/en not_active Ceased
- 2005-02-15 BR BRPI0507808-3A patent/BRPI0507808A/pt not_active IP Right Cessation
- 2005-02-15 CA CA2555236A patent/CA2555236C/en not_active Expired - Lifetime
- 2005-02-15 US US11/059,117 patent/US20050203046A1/en not_active Abandoned
- 2005-02-15 JP JP2006553342A patent/JP4949859B2/ja not_active Expired - Lifetime
- 2005-02-15 DE DE602005026105T patent/DE602005026105D1/de not_active Expired - Lifetime
- 2005-02-15 AT AT05713577T patent/ATE496636T1/de not_active IP Right Cessation
- 2005-02-15 WO PCT/US2005/004743 patent/WO2005079844A2/en not_active Ceased
- 2005-02-15 EP EP05713577A patent/EP1725261B1/en not_active Expired - Lifetime
- 2005-02-15 CN CNA2005800050705A patent/CN1917902A/zh active Pending
- 2005-02-16 TW TW101117025A patent/TW201304802A/zh unknown
- 2005-02-16 TW TW094104561A patent/TWI372628B/zh not_active IP Right Cessation
-
2006
- 2006-08-15 ZA ZA200606844A patent/ZA200606844B/xx unknown
- 2006-09-15 NO NO20064193A patent/NO20064193L/no not_active Application Discontinuation
-
2007
- 2007-03-05 US US11/682,224 patent/US20070160579A1/en not_active Abandoned
-
2008
- 2008-09-26 US US12/239,689 patent/US20090041718A1/en not_active Abandoned
-
2011
- 2011-06-13 JP JP2011131646A patent/JP2011178810A/ja active Pending
-
2014
- 2014-02-03 US US14/171,629 patent/US9970944B2/en active Active
- 2014-02-20 JP JP2014030239A patent/JP2014098026A/ja active Pending
-
2015
- 2015-08-21 JP JP2015163939A patent/JP2016034948A/ja active Pending
-
2017
- 2017-12-20 US US15/848,417 patent/US20180128837A1/en not_active Abandoned
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