NO20064193L - fremgangsmate for a modulere cytokinaktivitet, beslektede reagenser - Google Patents
fremgangsmate for a modulere cytokinaktivitet, beslektede reagenserInfo
- Publication number
- NO20064193L NO20064193L NO20064193A NO20064193A NO20064193L NO 20064193 L NO20064193 L NO 20064193L NO 20064193 A NO20064193 A NO 20064193A NO 20064193 A NO20064193 A NO 20064193A NO 20064193 L NO20064193 L NO 20064193L
- Authority
- NO
- Norway
- Prior art keywords
- cytokine activity
- modulating cytokine
- related reagents
- methods
- modulating
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
Abstract
Sammendrag Tilveiebrakt blir fremgangsmåter for modulering av cytokinaktivitet, f.eks. med det formålet å behandle immunforstyrrelser og inflammatoriske forstyrrelser, inkludert tumorer og kreft. Også tilveiebrakt er fremgangsmåter for administrering av agonister eller antagonister av IL-33 og IL-33reseptor
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54573004P | 2004-02-17 | 2004-02-17 | |
PCT/US2005/004743 WO2005079844A2 (en) | 2004-02-17 | 2005-02-15 | Use for interleukin-33 (il33) and the il-33 receptor complex |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064193L true NO20064193L (no) | 2006-11-16 |
Family
ID=34886190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064193A NO20064193L (no) | 2004-02-17 | 2006-09-15 | fremgangsmate for a modulere cytokinaktivitet, beslektede reagenser |
Country Status (14)
Country | Link |
---|---|
US (5) | US20050203046A1 (no) |
EP (2) | EP1725261B1 (no) |
JP (4) | JP4949859B2 (no) |
CN (1) | CN1917902A (no) |
AT (1) | ATE496636T1 (no) |
AU (1) | AU2005215528B2 (no) |
BR (1) | BRPI0507808A (no) |
CA (1) | CA2555236C (no) |
DE (1) | DE602005026105D1 (no) |
NO (1) | NO20064193L (no) |
NZ (1) | NZ549040A (no) |
TW (2) | TW201304802A (no) |
WO (1) | WO2005079844A2 (no) |
ZA (1) | ZA200606844B (no) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002218026A1 (en) | 2000-11-09 | 2002-05-21 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
EP3072978B1 (en) | 2002-05-09 | 2018-07-11 | The Brigham and Women's Hospital, Inc. | 1l1rl-1 as a cardiovascular disease marker |
NZ549040A (en) * | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
JP2009511572A (ja) * | 2005-10-16 | 2009-03-19 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | 炎症性皮膚疾患、障害または症状のための医薬組成物および診断方法 |
ES2351623T3 (es) * | 2006-04-24 | 2011-02-08 | Critical Care Diagnostics, Inc. | Predicción de la mortalidad y detección de una enfermedad grave. |
US20090305265A1 (en) * | 2006-04-27 | 2009-12-10 | Critical Care Diagnostics, Inc. | Interleukin-33 (il-33) for the diagnosis and prognosis of cardiovascular disease |
PT2021796E (pt) | 2006-05-01 | 2012-04-19 | Critical Care Diagnostics Inc | Diagnóstico de doença cardiovascular |
HUE025058T2 (en) * | 2006-05-02 | 2016-01-28 | Critical Care Diagnostics Inc | Differential diagnosis of pulmonary and cardiovascular disease |
WO2007130627A2 (en) * | 2006-05-04 | 2007-11-15 | The Brigham And Women's Hospital, Inc. | Il-33 in the treatment and diagnosis of diseases and disorders |
US7560530B1 (en) | 2006-07-20 | 2009-07-14 | Schering Corporation | IL-33 receptor |
SE532250C2 (sv) * | 2006-11-28 | 2009-11-24 | Theravac Pharmaceuticals Ab | Nya formuleringar av IL-33 för behandling av inflammatoriska tillstånd med en stark TH2 komponent genom vaccinering |
WO2008132709A1 (en) * | 2007-04-26 | 2008-11-06 | Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Products for altering il-33 activity and methods therefor |
JP2010527936A (ja) * | 2007-05-18 | 2010-08-19 | メディミューン,エルエルシー | 炎症性疾患におけるil−33 |
DK2827152T3 (en) | 2008-04-18 | 2016-09-12 | Critical Care Diagnostics Inc | PREDICTION OF RISK OF MAJOR ADVERSE HEART EVENTS |
JP5539660B2 (ja) * | 2009-03-10 | 2014-07-02 | 公益財団法人ヒューマンサイエンス振興財団 | 粘膜ワクチン用アジュバント |
ES2655079T3 (es) * | 2009-09-10 | 2018-02-16 | Merck Sharp & Dohme Corp. | Uso de antagonistas de IL-33 para tratar enfermedades fibróticas |
CA2824500C (en) * | 2011-02-23 | 2020-02-25 | Georg Fertig | Antibodies against human il33r and uses thereof |
FR2972006B1 (fr) | 2011-02-24 | 2016-03-25 | Centre Nat Rech Scient | Nouveaux fragments d'il-33 superactifs et leurs utilisations |
EP3605104B1 (en) | 2011-03-17 | 2021-09-15 | Critical Care Diagnostics, Inc. | Methods predicting risk of an adverse clinical outcome |
US9212227B2 (en) | 2012-04-30 | 2015-12-15 | Janssen Biotech, Inc. | ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions |
AR091069A1 (es) | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
CN104737170A (zh) | 2012-08-21 | 2015-06-24 | 重症监护诊断股份有限公司 | 多标记风险分层 |
WO2014090800A1 (en) * | 2012-12-10 | 2014-06-19 | Vib Vzw | Novel interleukin-33 inhibitors |
KR101780575B1 (ko) * | 2013-02-14 | 2017-09-21 | 건국대학교 산학협력단 | 신규한 인터루킨-33 수용체와 결합 단백질 조성물 및 그 용도 |
EP2958583B1 (en) * | 2013-02-22 | 2018-04-11 | Magic Epoch Holdings Limited | Il-33 and treatment of neurodegenerative diseases |
JO3532B1 (ar) | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
CA2904377C (en) * | 2013-03-15 | 2021-07-13 | Regeneron Pharmaceuticals, Inc. | Il-33 antagonists and uses thereof |
EP3782628B1 (en) * | 2013-03-15 | 2024-08-07 | Elixirgen Therapeutics, Inc. | Methods of using zscan4 for rejuvenating human cells |
WO2015042521A1 (en) | 2013-09-20 | 2015-03-26 | University Of Virginia Patent Foundation | Compositions and methods for treatment of autoimmune and inflammatory diseases and disorders |
CN111012905B (zh) * | 2013-10-07 | 2023-12-22 | 宾夕法尼亚大学理事会 | 具有作为佐剂的白介素-33的疫苗 |
FI3088517T3 (fi) * | 2013-12-26 | 2023-11-30 | Mitsubishi Tanabe Pharma Corp | Ihmisen Anti-IL-33 neutraloiva monoklonaalinen vasta-aine |
EP3092253B1 (en) | 2014-01-10 | 2021-03-17 | AnaptysBio, Inc. | Antibodies directed against interleukin-33 (il-33) |
WO2015143343A2 (en) | 2014-03-21 | 2015-09-24 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treatment of immune-related diseases or disorders and/or therapy monitoring |
JP7231326B2 (ja) * | 2014-11-10 | 2023-03-01 | ジェネンテック, インコーポレイテッド | Il-33媒介性障害のための治療及び診断方法 |
EA201791029A1 (ru) | 2014-11-10 | 2017-12-29 | Дженентек, Инк. | Антитела против интерлейкина-33 и их применение |
EP3265107B1 (en) | 2015-03-02 | 2024-10-02 | 180 Therapeutics LP | Method of treating a localized fibrotic disorder using a tnf receptor 2 antagonist |
EP3265114A4 (en) * | 2015-03-03 | 2019-11-13 | Jefferies, Wilfred | MODULATION OF ANTICANCER IMMUNITY USING INNED TYPE 2 LYMPHOID CELLS, INTERLEUKIN 33 AND / OR INTERFERON-INDUCED PROTEIN 44 |
WO2016156440A1 (en) | 2015-03-31 | 2016-10-06 | Medimmune Limited | A novel il33 form, mutated forms of il33, antibodies, assays and methods of using the same |
JP6501650B2 (ja) * | 2015-06-25 | 2019-04-17 | 田辺三菱製薬株式会社 | ヒト抗il−33中和モノクローナル抗体 |
US10813979B2 (en) * | 2015-07-10 | 2020-10-27 | The Hong Kong University Of Science And Technology | Methods and compositions for treating neurodegenerative and neuroinflammatory conditions |
AU2016333903B2 (en) * | 2015-10-06 | 2021-07-08 | Regeneron Pharmaceuticals, Inc. | Biomarkers related to interleukin-33 (IL-33)-mediated diseases and uses thereof |
KR101765397B1 (ko) | 2015-12-02 | 2017-08-07 | 한국과학기술원 | 질점막을 통한 바이러스 감염 취약 진단 마커로서의 il-33의 용도 |
CN109415436A (zh) | 2016-04-27 | 2019-03-01 | 辉瑞公司 | 抗il-33抗体及其组合物、方法及用途 |
SG10202100100UA (en) | 2016-06-29 | 2021-02-25 | Checkpoint Therapeutics Inc | Pd-l1-specific antibodies and methods of using the same |
JOP20190093A1 (ar) | 2016-10-28 | 2019-04-25 | Lilly Co Eli | أجسام مضادة لـ il-33 واستخداماتها |
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CN1917902A (zh) | 2007-02-21 |
CA2555236C (en) | 2015-05-05 |
WO2005079844A3 (en) | 2005-11-24 |
TWI372628B (en) | 2012-09-21 |
ZA200606844B (en) | 2008-05-28 |
ATE496636T1 (de) | 2011-02-15 |
EP2283860A2 (en) | 2011-02-16 |
NZ549040A (en) | 2009-07-31 |
US9970944B2 (en) | 2018-05-15 |
TW200539891A (en) | 2005-12-16 |
JP4949859B2 (ja) | 2012-06-13 |
US20090041718A1 (en) | 2009-02-12 |
US20140140954A1 (en) | 2014-05-22 |
US20180128837A1 (en) | 2018-05-10 |
AU2005215528A1 (en) | 2005-09-01 |
JP2007523089A (ja) | 2007-08-16 |
EP2283860A3 (en) | 2013-06-05 |
WO2005079844A2 (en) | 2005-09-01 |
JP2014098026A (ja) | 2014-05-29 |
CA2555236A1 (en) | 2005-09-01 |
US20050203046A1 (en) | 2005-09-15 |
US20070160579A1 (en) | 2007-07-12 |
TW201304802A (zh) | 2013-02-01 |
BRPI0507808A (pt) | 2007-07-10 |
JP2011178810A (ja) | 2011-09-15 |
EP1725261B1 (en) | 2011-01-26 |
AU2005215528B2 (en) | 2009-04-30 |
JP2016034948A (ja) | 2016-03-17 |
EP1725261A2 (en) | 2006-11-29 |
DE602005026105D1 (de) | 2011-03-10 |
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