JP2007522094A - 小分子組成物、及びその組成物を使用して薬物効率を高めるための方法 - Google Patents
小分子組成物、及びその組成物を使用して薬物効率を高めるための方法 Download PDFInfo
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- JP2007522094A JP2007522094A JP2006527154A JP2006527154A JP2007522094A JP 2007522094 A JP2007522094 A JP 2007522094A JP 2006527154 A JP2006527154 A JP 2006527154A JP 2006527154 A JP2006527154 A JP 2006527154A JP 2007522094 A JP2007522094 A JP 2007522094A
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- Prior art keywords
- alkyl
- aryl
- complex
- carbon atoms
- drug
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- Abandoned
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Classifications
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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| US50532503P | 2003-09-22 | 2003-09-22 | |
| US58183504P | 2004-06-22 | 2004-06-22 | |
| PCT/US2004/031147 WO2005030258A2 (en) | 2003-09-22 | 2004-09-22 | Small molecule compositions and methods for increasing drug efficiency using compositions thereof |
Publications (2)
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| JP2007522094A true JP2007522094A (ja) | 2007-08-09 |
| JP2007522094A5 JP2007522094A5 (https=) | 2007-12-06 |
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| JP2006527154A Abandoned JP2007522094A (ja) | 2003-09-22 | 2004-09-22 | 小分子組成物、及びその組成物を使用して薬物効率を高めるための方法 |
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| EP (1) | EP1689439A2 (https=) |
| JP (1) | JP2007522094A (https=) |
| AU (1) | AU2004275770A1 (https=) |
| CA (1) | CA2539914A1 (https=) |
| WO (1) | WO2005030258A2 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014196358A (ja) * | 2008-05-23 | 2014-10-16 | ザ ユニヴァーシティ オブ ブリティッシュ コロンビア | リポソームナノ粒子中で使用するための修飾薬物 |
| JP2021523946A (ja) * | 2018-05-15 | 2021-09-09 | インテルク ペプチド セラピューティクス リミテッド | ペプチド活性化剤 |
| JP2021523945A (ja) * | 2018-05-15 | 2021-09-09 | インテルク ペプチド セラピューティクス リミテッド | 活性化剤 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| EP1736478B1 (en) | 2000-05-26 | 2015-07-22 | IDENIX Pharmaceuticals, Inc. | Methods and compositions for treating flaviviruses and pestiviruses |
| CN1678326A (zh) | 2002-06-28 | 2005-10-05 | 埃迪尼克斯(开曼)有限公司 | 用于治疗黄病毒感染的2'－c－甲基－3'－o－l－缬氨酸酯核糖呋喃基胞苷 |
| NZ537662A (en) | 2002-06-28 | 2007-10-26 | Idenix Cayman Ltd | 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
| LT1576138T (lt) | 2002-11-15 | 2017-06-26 | Idenix Pharmaceuticals Llc | 2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija |
| AU2003300901A1 (en) | 2002-12-12 | 2004-06-30 | Idenix (Cayman) Limited | Process for the production of 2'-branched nucleosides |
| US8138361B2 (en) | 2005-12-28 | 2012-03-20 | The Trustees Of The University Of Pennsylvania | C-10 carbamates of taxanes |
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| ES2442024T3 (es) | 2008-07-15 | 2014-02-07 | Academia Sinica | Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| WO2014031498A1 (en) | 2012-08-18 | 2014-02-27 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| ES2671478T3 (es) | 2012-08-31 | 2018-06-06 | Novartis Ag | Derivados de 2'-etinil nucleósidos para el tratamiento de infecciones virales |
| JP2016501200A (ja) | 2012-11-19 | 2016-01-18 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | ウイルス性疾患を処置するための２−アルキニル置換ヌクレオシド誘導体 |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| EP3013347B1 (en) * | 2013-06-27 | 2019-12-11 | Academia Sinica | Glycan conjugates and use thereof |
| JP6486368B2 (ja) | 2013-09-06 | 2019-03-20 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | 改変されたグリコシル基を含む糖脂質を用いたヒトｉＮＫＴ細胞の活性化 |
| AU2015206370A1 (en) | 2014-01-16 | 2016-07-07 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| CN106415244B (zh) | 2014-03-27 | 2020-04-24 | 中央研究院 | 反应性标记化合物及其用途 |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| CN106661099A (zh) | 2014-05-27 | 2017-05-10 | 中央研究院 | 抗her2醣抗体及其用途 |
| CA2950415A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
| JP7093612B2 (ja) | 2014-05-27 | 2022-06-30 | アカデミア シニカ | Ｂａｃｔｅｒｏｉｄｅｓ由来のフコシダーゼおよびそれを使用する方法 |
| WO2015184001A1 (en) | 2014-05-28 | 2015-12-03 | Academia Sinica | Anti-tnf-alpha glycoantibodies and uses thereof |
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| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
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| JP6779887B2 (ja) | 2015-01-24 | 2020-11-04 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | 新規なグリカンコンジュゲートおよびその使用方法 |
| EP3426693A4 (en) | 2016-03-08 | 2019-11-13 | Academia Sinica | PROCESS FOR MODULAR SYNTHESIS OF N-GLYCANES AND ARRANGEMENTS THEREOF |
| CA3034057A1 (en) | 2016-08-22 | 2018-03-01 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL59083A (en) * | 1979-01-10 | 1983-12-30 | Israel Marcus | Pharmaceutical composition containing thymidine and a salicyclic acid derivative as a solubilizing agent therefor |
| US5608049A (en) * | 1995-03-10 | 1997-03-04 | Bristol-Myers Squibb Company | Preparation of d4T from 5-methyluridine |
| US5723589A (en) * | 1995-12-21 | 1998-03-03 | Icn Pharmaceuticals | Carbohydrate conjugated bio-active compounds |
-
2004
- 2004-09-22 CA CA002539914A patent/CA2539914A1/en not_active Abandoned
- 2004-09-22 EP EP04784836A patent/EP1689439A2/en not_active Withdrawn
- 2004-09-22 WO PCT/US2004/031147 patent/WO2005030258A2/en not_active Ceased
- 2004-09-22 AU AU2004275770A patent/AU2004275770A1/en not_active Abandoned
- 2004-09-22 JP JP2006527154A patent/JP2007522094A/ja not_active Abandoned
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2014196358A (ja) * | 2008-05-23 | 2014-10-16 | ザ ユニヴァーシティ オブ ブリティッシュ コロンビア | リポソームナノ粒子中で使用するための修飾薬物 |
| KR101830018B1 (ko) | 2008-05-23 | 2018-02-19 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 리포좀 나노입자에 사용하기 위한 변형된 약물 |
| KR101919093B1 (ko) | 2008-05-23 | 2018-11-16 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 리포좀 나노입자에 사용하기 위한 변형된 약물 |
| KR20180123595A (ko) * | 2008-05-23 | 2018-11-16 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 리포좀 나노입자에 사용하기 위한 변형된 약물 |
| KR101975843B1 (ko) | 2008-05-23 | 2019-05-09 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 리포좀 나노입자에 사용하기 위한 변형된 약물 |
| JP2021523946A (ja) * | 2018-05-15 | 2021-09-09 | インテルク ペプチド セラピューティクス リミテッド | ペプチド活性化剤 |
| JP2021523945A (ja) * | 2018-05-15 | 2021-09-09 | インテルク ペプチド セラピューティクス リミテッド | 活性化剤 |
| JP7386852B2 (ja) | 2018-05-15 | 2023-11-27 | インテルク ペプチド セラピューティクス リミテッド | ペプチド活性化剤 |
| US12134663B2 (en) | 2018-05-15 | 2024-11-05 | Interk Peptide Therapeutics Limited | Cationic peptides for activating Lck |
| JP7644000B2 (ja) | 2018-05-15 | 2025-03-11 | インテルク ペプチド セラピューティクス リミテッド | 活性化剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2539914A1 (en) | 2005-04-07 |
| WO2005030258A2 (en) | 2005-04-07 |
| EP1689439A2 (en) | 2006-08-16 |
| WO2005030258A3 (en) | 2005-09-22 |
| AU2004275770A1 (en) | 2005-04-07 |
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