JP2007521920A5 - - Google Patents
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- Publication number
- JP2007521920A5 JP2007521920A5 JP2006553177A JP2006553177A JP2007521920A5 JP 2007521920 A5 JP2007521920 A5 JP 2007521920A5 JP 2006553177 A JP2006553177 A JP 2006553177A JP 2006553177 A JP2006553177 A JP 2006553177A JP 2007521920 A5 JP2007521920 A5 JP 2007521920A5
- Authority
- JP
- Japan
- Prior art keywords
- retinal
- autofluorescence
- excitation light
- aligning
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002207 retinal effect Effects 0.000 claims 41
- 230000005284 excitation Effects 0.000 claims 33
- 238000005259 measurement Methods 0.000 claims 23
- 238000000034 method Methods 0.000 claims 23
- 230000002503 metabolic effect Effects 0.000 claims 15
- 210000001525 retina Anatomy 0.000 claims 15
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims 14
- 102000004169 proteins and genes Human genes 0.000 claims 14
- 108090000623 proteins and genes Proteins 0.000 claims 14
- 238000001514 detection method Methods 0.000 claims 7
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 2
- 229910052753 mercury Inorganic materials 0.000 claims 2
- 239000013307 optical fiber Substances 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/777,423 US7512436B2 (en) | 2004-02-12 | 2004-02-12 | Method of evaluating metabolism of the eye |
| PCT/US2005/003837 WO2005079238A2 (en) | 2004-02-12 | 2005-02-08 | Method of evaluating metabolism of the eye |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007521920A JP2007521920A (ja) | 2007-08-09 |
| JP2007521920A5 true JP2007521920A5 (enExample) | 2008-03-27 |
Family
ID=34837987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553177A Pending JP2007521920A (ja) | 2004-02-12 | 2005-02-08 | 眼の代謝の評価方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7512436B2 (enExample) |
| EP (2) | EP1761171A4 (enExample) |
| JP (1) | JP2007521920A (enExample) |
| CA (1) | CA2555782C (enExample) |
| WO (1) | WO2005079238A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7512436B2 (en) * | 2004-02-12 | 2009-03-31 | The Regents Of The University Of Michigan | Method of evaluating metabolism of the eye |
| US10039445B1 (en) * | 2004-04-01 | 2018-08-07 | Google Llc | Biosensors, communicators, and controllers monitoring eye movement and methods for using them |
| US7365856B2 (en) | 2005-01-21 | 2008-04-29 | Carl Zeiss Meditec, Inc. | Method of motion correction in optical coherence tomography imaging |
| US7805009B2 (en) | 2005-04-06 | 2010-09-28 | Carl Zeiss Meditec, Inc. | Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system |
| US20070122344A1 (en) | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
| AT502855B1 (de) * | 2005-11-30 | 2009-10-15 | Oridis Biomed Forschungs Und E | Verfahren und vorrichtung zur automatischen zerstörungsfreien analyse einer vielzahl von biologischen proben |
| US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
| US20080129961A1 (en) * | 2006-11-30 | 2008-06-05 | Abraham Schwartz | Method and apparatus for measuring quantity of a fluorochrome in a biological environment |
| US7648239B2 (en) * | 2007-05-01 | 2010-01-19 | Richard Spaide | Autofluorescence photography using a fundus camera |
| US7670003B2 (en) | 2007-07-26 | 2010-03-02 | Ophthalmology Associates of Northwestern Ohio, Inc. | Examination assembly with improved access for the wheelchair bound patient |
| KR101643953B1 (ko) * | 2007-11-13 | 2016-07-29 | 더 리젠츠 오브 더 유니버시티 오브 미시건 | 눈과 관련된 질환을 검출하기 위한 방법 및 장치 |
| DE102007061987A1 (de) * | 2007-12-21 | 2009-06-25 | Carl Zeiss Meditec Ag | Vorrichtung und Verfahren zum Nachweisen von Molekülen im Auge |
| US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
| US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
| BRPI0907272A2 (pt) * | 2008-04-14 | 2015-07-21 | Novadaq Technologies Inc | "método de avaliação e aparelho de avaliação de perfusão de vasos perfurantes" |
| WO2009135178A2 (en) | 2008-05-02 | 2009-11-05 | Flower Robert W | Methods for production and use of substance-loaded erythrocytes (s-les) for observation and treatment of microvascular hemodynamics |
| US20110228219A1 (en) * | 2008-11-25 | 2011-09-22 | Nihon University | Ophthalmic simulator |
| US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
| WO2011059405A1 (en) * | 2009-11-12 | 2011-05-19 | Agency For Science, Technology And Research | Method and device for monitoring retinopathy |
| US20110129133A1 (en) * | 2009-12-02 | 2011-06-02 | Ramos Joao Diogo De Oliveira E | Methods and systems for detection of retinal changes |
| US9033510B2 (en) | 2011-03-30 | 2015-05-19 | Carl Zeiss Meditec, Inc. | Systems and methods for efficiently obtaining measurements of the human eye using tracking |
| US8857988B2 (en) | 2011-07-07 | 2014-10-14 | Carl Zeiss Meditec, Inc. | Data acquisition methods for reduced motion artifacts and applications in OCT angiography |
| US9101294B2 (en) | 2012-01-19 | 2015-08-11 | Carl Zeiss Meditec, Inc. | Systems and methods for enhanced accuracy in OCT imaging of the cornea |
| WO2013180660A1 (en) * | 2012-06-01 | 2013-12-05 | Agency For Science, Technology And Research | Robust graph representation and matching of retina images |
| US9482617B2 (en) * | 2012-06-07 | 2016-11-01 | Jeffrey M. Smith | Method for optical detection of surveillance and sniper personnel |
| EP2863801B8 (en) | 2012-06-21 | 2024-06-12 | Stryker Corporation | Quantification and analysis of angiography and perfusion |
| JP5962302B2 (ja) * | 2012-07-30 | 2016-08-03 | 株式会社ニデック | 眼底撮影装置 |
| US9179834B2 (en) * | 2013-02-01 | 2015-11-10 | Kabushiki Kaisha Topcon | Attenuation-based optic neuropathy detection with three-dimensional optical coherence tomography |
| WO2015013632A1 (en) | 2013-07-26 | 2015-01-29 | The Regents Of The University Of Michigan | Automated measurement of changes in retinal, retinal pigment epithelial, or choroidal disease |
| US9949637B1 (en) * | 2013-11-25 | 2018-04-24 | Verily Life Sciences Llc | Fluorescent imaging on a head-mountable device |
| US9526412B2 (en) | 2014-01-21 | 2016-12-27 | Kabushiki Kaisha Topcon | Geographic atrophy identification and measurement |
| CN107209118B (zh) | 2014-09-29 | 2021-05-28 | 史赛克欧洲运营有限公司 | 在自体荧光存在下生物材料中目标荧光团的成像 |
| AU2014408488B2 (en) | 2014-10-09 | 2019-07-18 | Stryker European Operations Limited | Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography |
| US10117568B2 (en) | 2015-01-15 | 2018-11-06 | Kabushiki Kaisha Topcon | Geographic atrophy identification and measurement |
| EP3270765B1 (en) | 2015-03-20 | 2020-05-06 | Glaukos Corporation | Gonioscopic devices |
| US9757023B2 (en) | 2015-05-27 | 2017-09-12 | The Regents Of The University Of Michigan | Optic disc detection in retinal autofluorescence images |
| AU2016311449B2 (en) | 2015-08-27 | 2019-01-03 | Balance Ophthalmics, Inc. | Eye-related intrabody pressure identification and modification |
| US10314473B2 (en) * | 2015-09-09 | 2019-06-11 | New York University | System and method for in vivo detection of fluorescence from an eye |
| US10359613B2 (en) * | 2016-08-10 | 2019-07-23 | Kla-Tencor Corporation | Optical measurement of step size and plated metal thickness |
| US20180045937A1 (en) * | 2016-08-10 | 2018-02-15 | Zeta Instruments, Inc. | Automated 3-d measurement |
| SG11201901045UA (en) * | 2016-08-10 | 2019-03-28 | Kla Tencor Corp | Optical measurement of bump height |
| JP6931705B2 (ja) | 2017-02-10 | 2021-09-08 | ノバダック テクノロジーズ ユーエルシー | オープンフィールドハンドヘルド蛍光イメージングシステムおよび方法 |
| US10674906B2 (en) | 2017-02-24 | 2020-06-09 | Glaukos Corporation | Gonioscopes |
| USD833008S1 (en) | 2017-02-27 | 2018-11-06 | Glaukos Corporation | Gonioscope |
| US10506925B2 (en) | 2017-02-27 | 2019-12-17 | Zeavision, Llc | Reflectometry instrument and method for measuring macular pigment |
| WO2019014205A1 (en) * | 2017-07-10 | 2019-01-17 | University Of Kentucky Research Foundation | PEROPERATIVE FLUORESCENCE IMAGING DEVICE BASED ON MAGNIFIER FOR GUIDING A TUMOR RESECTION |
| WO2020033736A1 (en) | 2018-08-09 | 2020-02-13 | Equinox Ophthalmic, Inc. | Apparatus and methods to adjust ocular blood flow |
| US12440099B2 (en) | 2020-06-18 | 2025-10-14 | Prn Physician Recommended Nutriceuticals Llc | Handheld device for measuring macular pigment |
| ES2973786T3 (es) | 2020-06-18 | 2024-06-24 | Zeavision Llc | Dispositivo portátil para medir el pigmento macular |
| USD1023313S1 (en) | 2021-06-17 | 2024-04-16 | Zeavision Llc | Instrument for measuring eye-health characteristics |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4569354A (en) * | 1982-03-22 | 1986-02-11 | Boston University | Method and apparatus for measuring natural retinal fluorescence |
| US5784162A (en) | 1993-08-18 | 1998-07-21 | Applied Spectral Imaging Ltd. | Spectral bio-imaging methods for biological research, medical diagnostics and therapy |
| US6198532B1 (en) * | 1991-02-22 | 2001-03-06 | Applied Spectral Imaging Ltd. | Spectral bio-imaging of the eye |
| PT101290B (pt) * | 1993-06-18 | 2000-10-31 | Fernandes Jose Guilherme Da Cu | Fluorometro para medicao da concentracao de fluoroforos de localizacao ocular |
| JPH0824223A (ja) * | 1994-07-15 | 1996-01-30 | Canon Inc | 眼科撮影装置 |
| US5976822A (en) * | 1995-05-18 | 1999-11-02 | Coulter International Corp. | Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis |
| JP2001521422A (ja) * | 1997-04-17 | 2001-11-06 | アビモ グループ リミテッド | 眼の微小循環検査および処理装置 |
| NL1007011C2 (nl) | 1997-09-11 | 1999-03-12 | Rijksuniversiteit | Inrichting voor het meten van de fluorescentie van de cornea van een oog. |
| JPH11206711A (ja) * | 1998-01-23 | 1999-08-03 | Nikon Corp | 検眼装置 |
| WO1999047041A1 (en) * | 1998-03-19 | 1999-09-23 | Board Of Regents, The University Of Texas System | Fiber-optic confocal imaging apparatus and methods of use |
| US6475424B1 (en) * | 1998-05-14 | 2002-11-05 | Cambridge Industries, Inc. | Multi-process molding method and article produced by same |
| IL125614A (en) * | 1998-07-31 | 2003-01-12 | Amiram Grinvald | System and method for non-invasive imaging of retinal function |
| US6276798B1 (en) * | 1998-09-29 | 2001-08-21 | Applied Spectral Imaging, Ltd. | Spectral bio-imaging of the eye |
| US6564853B1 (en) * | 1998-10-13 | 2003-05-20 | Water Gremlin Company | Multiple casting apparatus and method |
| WO2000040089A1 (en) * | 1999-01-05 | 2000-07-13 | Massachusetts Eye And Ear Infirmary | Targeted transscleral controlled release drug delivery to the retina and choroid |
| DE19907479A1 (de) * | 1999-02-15 | 2000-08-17 | Univ Schiller Jena | Verfahren und Vorrichtung zur Messung unterschiedlicher Fluoreszenzspektren an einem Objekt |
| US6236881B1 (en) * | 1999-04-26 | 2001-05-22 | Contec Medical Ltd. | Method and apparatus for differentiating and processing images of normal benign and pre-cancerous and cancerous lesioned tissues using mixed reflected and autofluoresced light |
| DE19920158A1 (de) * | 1999-04-29 | 2000-11-02 | Univ Schiller Jena | Verfahren und Anordnung zur Bestimmung von Fluorophoren an Objekten, insbesondere am lebenden Augenhintergrund |
| JP2001245852A (ja) * | 2000-03-03 | 2001-09-11 | Canon Inc | 検眼装置 |
| JP4557359B2 (ja) * | 2000-03-31 | 2010-10-06 | 株式会社トプコン | 眼科装置 |
| AU2002251877A1 (en) * | 2001-02-06 | 2002-08-19 | Argose, Inc. | Layered calibration standard for tissue sampling |
| US20030004418A1 (en) * | 2001-06-15 | 2003-01-02 | Marmorstein Alan D. | Apparatus and method for ratiometric quantitation of elicited autofluorescence of the eye |
| US20030170898A1 (en) * | 2001-12-04 | 2003-09-11 | Gundersen Martin A. | Method for intracellular modifications within living cells using pulsed electric fields |
| US20030129583A1 (en) * | 2002-01-08 | 2003-07-10 | Martin William John | Therapy of stealth virus associated cancers and other conditions using light |
| IL148795A0 (en) * | 2002-03-20 | 2002-09-12 | Vital Medical Ltd | Apparatus and method for monitoring tissue vitality parameters for the diagnosis of body metabolic emergency state |
| ITRM20020492A1 (it) * | 2002-10-01 | 2004-04-02 | Sigma Tau Ind Farmaceuti | Uso della propionil l-carnitina per la preparazione di un medicamento per il trattamento del glaucoma. |
| CA2501348A1 (en) * | 2002-10-08 | 2004-04-22 | Allergan, Inc. | Treatment of dementia and parkinson's disease |
| US7365844B2 (en) * | 2002-12-10 | 2008-04-29 | Board Of Regents, The University Of Texas System | Vision enhancement system for improved detection of epithelial neoplasia and other conditions |
| WO2004096033A1 (en) * | 2003-05-01 | 2004-11-11 | Millennium Diet And Nutriceuticals Limited | Measurement of distribution of macular pigment |
| US20050065436A1 (en) * | 2003-09-23 | 2005-03-24 | Ho Winston Zonh | Rapid and non-invasive optical detection of internal bleeding |
| US7706863B2 (en) * | 2004-01-21 | 2010-04-27 | University Of Washington | Methods for assessing a physiological state of a mammalian retina |
| US7512436B2 (en) * | 2004-02-12 | 2009-03-31 | The Regents Of The University Of Michigan | Method of evaluating metabolism of the eye |
| SG144145A1 (en) * | 2004-12-08 | 2008-07-29 | Sirion Therapeutics Inc | Methods, assays and compositions for treating retinol-related diseases |
-
2004
- 2004-02-12 US US10/777,423 patent/US7512436B2/en not_active Expired - Lifetime
-
2005
- 2005-02-08 JP JP2006553177A patent/JP2007521920A/ja active Pending
- 2005-02-08 EP EP05722799A patent/EP1761171A4/en not_active Withdrawn
- 2005-02-08 CA CA2555782A patent/CA2555782C/en not_active Expired - Lifetime
- 2005-02-08 EP EP12153021A patent/EP2449958A1/en not_active Withdrawn
- 2005-02-08 WO PCT/US2005/003837 patent/WO2005079238A2/en not_active Ceased
-
2009
- 2009-02-06 US US12/366,921 patent/US8781559B2/en not_active Expired - Lifetime
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