JP2007513634A5 - - Google Patents
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- JP2007513634A5 JP2007513634A5 JP2006544104A JP2006544104A JP2007513634A5 JP 2007513634 A5 JP2007513634 A5 JP 2007513634A5 JP 2006544104 A JP2006544104 A JP 2006544104A JP 2006544104 A JP2006544104 A JP 2006544104A JP 2007513634 A5 JP2007513634 A5 JP 2007513634A5
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- JP
- Japan
- Prior art keywords
- hbc
- sequence
- residues
- residue
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 21
- 125000000539 amino acid group Chemical group 0.000 claims 20
- 239000002245 particle Substances 0.000 claims 17
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 102000039446 nucleic acids Human genes 0.000 claims 11
- 108020004707 nucleic acids Proteins 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 235000018102 proteins Nutrition 0.000 claims 11
- 102000004169 proteins and genes Human genes 0.000 claims 11
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 241000737598 recombinant Hepatitis B virus Species 0.000 claims 6
- 230000002163 immunogen Effects 0.000 claims 5
- 208000037797 influenza A Diseases 0.000 claims 5
- 230000000295 complement effect Effects 0.000 claims 4
- 102000005741 Metalloproteases Human genes 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 102000037865 fusion proteins Human genes 0.000 claims 2
- 108020001507 fusion proteins Proteins 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000002054 inoculum Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 241000712431 Influenza A virus Species 0.000 claims 1
- 108010006035 Metalloproteases Proteins 0.000 claims 1
- 102000012479 Serine Proteases Human genes 0.000 claims 1
- 108010022999 Serine Proteases Proteins 0.000 claims 1
- 101710102218 Serine protease inhibitor Proteins 0.000 claims 1
- 229940122055 Serine protease inhibitor Drugs 0.000 claims 1
- 101000998548 Yersinia ruckeri Alkaline proteinase inhibitor Proteins 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 239000003475 metalloproteinase inhibitor Substances 0.000 claims 1
- 239000000203 mixture Chemical group 0.000 claims 1
- 239000003001 serine protease inhibitor Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/732,862 US20040146524A1 (en) | 2002-02-21 | 2003-12-10 | Stabilized immunogenic HBc chimer particles |
| US10/787,734 US7361352B2 (en) | 2001-08-15 | 2004-02-26 | Influenza immunogen and vaccine |
| PCT/US2004/041879 WO2005055957A2 (en) | 2003-12-10 | 2004-12-09 | Influenza immunogen and vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007513634A JP2007513634A (ja) | 2007-05-31 |
| JP2007513634A5 true JP2007513634A5 (https=) | 2008-02-07 |
Family
ID=34681746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006544104A Pending JP2007513634A (ja) | 2003-12-10 | 2004-12-09 | インフルエンザ免疫原及びワクチン |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7361352B2 (https=) |
| EP (2) | EP2425848A3 (https=) |
| JP (1) | JP2007513634A (https=) |
| KR (1) | KR101209484B1 (https=) |
| CN (1) | CN1913920B (https=) |
| AU (1) | AU2004296886B2 (https=) |
| BR (1) | BRPI0417509A (https=) |
| CA (1) | CA2549104A1 (https=) |
| IL (1) | IL200341A (https=) |
| NO (1) | NO20063157L (https=) |
| WO (1) | WO2005055957A2 (https=) |
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2004
- 2004-02-26 US US10/787,734 patent/US7361352B2/en not_active Expired - Fee Related
- 2004-12-09 BR BRPI0417509-3A patent/BRPI0417509A/pt not_active IP Right Cessation
- 2004-12-09 EP EP11182824A patent/EP2425848A3/en not_active Withdrawn
- 2004-12-09 WO PCT/US2004/041879 patent/WO2005055957A2/en not_active Ceased
- 2004-12-09 JP JP2006544104A patent/JP2007513634A/ja active Pending
- 2004-12-09 AU AU2004296886A patent/AU2004296886B2/en not_active Ceased
- 2004-12-09 CA CA002549104A patent/CA2549104A1/en not_active Abandoned
- 2004-12-09 EP EP04814103A patent/EP1708748A4/en not_active Withdrawn
- 2004-12-09 CN CN2004800414514A patent/CN1913920B/zh not_active Expired - Fee Related
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2006
- 2006-06-09 KR KR1020067011453A patent/KR101209484B1/ko not_active Expired - Fee Related
- 2006-07-07 NO NO20063157A patent/NO20063157L/no not_active Application Discontinuation
- 2006-08-24 US US11/509,382 patent/US8017127B2/en not_active Expired - Fee Related
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2009
- 2009-08-11 IL IL200341A patent/IL200341A/en not_active IP Right Cessation