JP2007511593A5 - - Google Patents
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- JP2007511593A5 JP2007511593A5 JP2006540587A JP2006540587A JP2007511593A5 JP 2007511593 A5 JP2007511593 A5 JP 2007511593A5 JP 2006540587 A JP2006540587 A JP 2006540587A JP 2006540587 A JP2006540587 A JP 2006540587A JP 2007511593 A5 JP2007511593 A5 JP 2007511593A5
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- JP
- Japan
- Prior art keywords
- fragment
- antibody
- pharmaceutical composition
- inhibitor
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0327181A GB0327181D0 (en) | 2003-11-21 | 2003-11-21 | Biological products |
| GB0327181.4 | 2003-11-21 | ||
| GB0417115A GB0417115D0 (en) | 2004-07-30 | 2004-07-30 | Biological products |
| GB0417115.3 | 2004-07-30 | ||
| PCT/GB2004/004850 WO2005051422A1 (en) | 2003-11-21 | 2004-11-16 | Method for the treatment of multiple sclerosis by inhibiting il-17 activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007511593A JP2007511593A (ja) | 2007-05-10 |
| JP2007511593A5 true JP2007511593A5 (https=) | 2007-11-08 |
| JP4833850B2 JP4833850B2 (ja) | 2011-12-07 |
Family
ID=34635441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540587A Expired - Fee Related JP4833850B2 (ja) | 2003-11-21 | 2004-11-16 | Ｉｌ−１７活性阻害による多発性硬化症を治療するための方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20070269428A1 (https=) |
| EP (3) | EP2974742A1 (https=) |
| JP (1) | JP4833850B2 (https=) |
| AT (1) | ATE395083T1 (https=) |
| AU (1) | AU2004292393C1 (https=) |
| CA (1) | CA2544920C (https=) |
| CY (1) | CY1116992T1 (https=) |
| DE (1) | DE602004013825D1 (https=) |
| DK (1) | DK1983000T3 (https=) |
| ES (2) | ES2554645T3 (https=) |
| HR (1) | HRP20151210T1 (https=) |
| HU (1) | HUE026260T2 (https=) |
| PL (1) | PL1983000T3 (https=) |
| PT (1) | PT1983000E (https=) |
| SI (1) | SI1983000T1 (https=) |
| WO (1) | WO2005051422A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1013141A (en) * | 1960-12-30 | 1965-12-15 | Secr Aviation | Improvements in or relating to the stabilisation of electronic oscillators |
| US20070160576A1 (en) * | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| US20040219150A1 (en) * | 2003-02-06 | 2004-11-04 | Cua Daniel J. | Uses of mammalian cytokine; related reagents |
| PL2784084T5 (pl) | 2003-07-08 | 2024-12-02 | Novartis Pharma Ag | Przeciwciała antagonistyczne heterologicznych polipeptydów il-17a/f |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| GB0425569D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
| CN101326195B9 (zh) | 2005-12-13 | 2022-11-11 | 伊莱利利公司 | 抗il-17抗体 |
| WO2007071439A1 (en) * | 2005-12-22 | 2007-06-28 | Laboratoires Serono S.A. | Soluble il-17rc variant and uses thereof |
| US20070218065A1 (en) | 2006-03-10 | 2007-09-20 | Jaspers Stephen R | Antibodies that bind both il-17a and il-17f and methods of using the same |
| US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| US7790163B2 (en) | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
| GB0612928D0 (en) * | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| CA2660463C (en) | 2006-08-11 | 2013-07-16 | Schering Corporation | Antibodies to il-17a |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| JPWO2009054454A1 (ja) | 2007-10-24 | 2011-03-03 | 国立大学法人 東京医科歯科大学 | カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤 |
| WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| GB0807413D0 (en) * | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| SG10201608871XA (en) | 2008-05-05 | 2016-12-29 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| JP5581323B2 (ja) | 2008-09-29 | 2014-08-27 | ロシュ グリクアート アクチェンゲゼルシャフト | ヒトｉｌ１７に対する抗体およびその使用 |
| WO2010062858A1 (en) * | 2008-11-26 | 2010-06-03 | Allergan, Inc. | Il-17 antibody inhibitor for treating dry eye |
| WO2010062857A1 (en) | 2008-11-26 | 2010-06-03 | Allergan, Inc. | Klk-13 antibody inhibitor for treating dry eye |
| CA2759848C (en) | 2009-05-05 | 2018-12-04 | Novimmune S.A. | Anti-il-17f antibodies and methods of use thereof |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
| MX2012002428A (es) * | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| WO2011100637A1 (en) | 2010-02-11 | 2011-08-18 | The Board Of Trustees Of The Leland Stanford Junior University | Markers for determination of patient responsiveness |
| GB201100282D0 (en) | 2011-01-07 | 2011-02-23 | Ucb Pharma Sa | Biological methods |
| US10208349B2 (en) | 2011-01-07 | 2019-02-19 | Ucb Biopharma Sprl | Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy |
| SG10201510762YA (en) | 2011-01-14 | 2016-01-28 | Ucb Pharma Sa | Antibody molecules which bind il-17a and il-17f |
| WO2012116926A1 (en) | 2011-02-28 | 2012-09-07 | F. Hoffmann-La Roche Ag | Antigen binding proteins |
| JP5768147B2 (ja) | 2011-02-28 | 2015-08-26 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 一価抗原結合タンパク質 |
| WO2013150043A1 (en) | 2012-04-05 | 2013-10-10 | F. Hoffmann-La Roche Ag | Bispecific antibodies against human tweak and human il17 and uses thereof |
| WO2014155278A2 (en) * | 2013-03-26 | 2014-10-02 | Novartis Ag | Methods of treating autoimmune diseases using il-17 antagonists |
| WO2014161570A1 (en) | 2013-04-03 | 2014-10-09 | Roche Glycart Ag | Antibodies against human il17 and uses thereof |
| KR20160044060A (ko) | 2013-10-11 | 2016-04-22 | 에프. 호프만-라 로슈 아게 | 다중특이적 도메인 교환된 통상의 가변 경쇄 항체 |
| UA117289C2 (uk) | 2014-04-02 | 2018-07-10 | Ф. Хоффманн-Ля Рош Аг | Мультиспецифічне антитіло |
| KR20180039726A (ko) | 2015-09-04 | 2018-04-18 | 더 캘리포니아 인스티튜트 포 바이오메디칼 리써치 | 인슐린 면역글로불린 융합 단백질 |
| EP3150637A1 (en) | 2015-10-02 | 2017-04-05 | F. Hoffmann-La Roche AG | Multispecific antibodies |
| RU2680011C2 (ru) | 2016-04-29 | 2019-02-14 | Закрытое Акционерное Общество "Биокад" | Триспецифические антитела против il-17a, il-17f и другой провоспалительной молекулы |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| GB2561352B (en) * | 2017-04-10 | 2023-01-18 | Genome Res Ltd | Animal models and therapeutic molecules |
Family Cites Families (55)
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|---|---|---|---|---|
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) * | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) * | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US4980286A (en) * | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
| US5677425A (en) * | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| WO1991010737A1 (en) | 1990-01-11 | 1991-07-25 | Molecular Affinities Corporation | Production of antibodies using gene libraries |
| US5780225A (en) | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
| US5427908A (en) * | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) * | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0542810A1 (en) | 1990-08-02 | 1993-05-26 | B.R. Centre Limited | Methods for the production of proteins with a desired function |
| US5698426A (en) | 1990-09-28 | 1997-12-16 | Ixsys, Incorporated | Surface expression libraries of heteromeric receptors |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| DK0580737T3 (da) | 1991-04-10 | 2004-11-01 | Scripps Research Inst | Heterodimere receptorbiblioteker ved anvendelse af phagemider |
| GB9113120D0 (en) | 1991-06-18 | 1991-08-07 | Kodak Ltd | Photographic processing apparatus |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5383851A (en) * | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5807683A (en) * | 1992-11-19 | 1998-09-15 | Combichem, Inc. | Combinatorial libraries and methods for their use |
| US6562333B1 (en) | 1993-06-14 | 2003-05-13 | Schering Corporation | Purified mammalian CTLA-8 antigens and related reagents |
| US6274711B1 (en) * | 1993-06-14 | 2001-08-14 | Inserm, Institut National De La Sante Et De La Recherche Medicale | Purified mammalian CTLA-8 antigens and related reagents |
| EP0733070A1 (en) | 1993-12-08 | 1996-09-25 | Genzyme Corporation | Process for generating specific antibodies |
| PT1231268E (pt) | 1994-01-31 | 2005-11-30 | Univ Boston | Bancos de anticorpos policlonais |
| US5738996A (en) * | 1994-06-15 | 1998-04-14 | Pence, Inc. | Combinational library composition and method |
| US5516637A (en) | 1994-06-10 | 1996-05-14 | Dade International Inc. | Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage |
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| EP0839196B1 (en) | 1995-07-19 | 2005-05-11 | Genetics Institute, LLC | Human ctla-8 and uses of ctla-8-related proteins |
| JP2978435B2 (ja) * | 1996-01-24 | 1999-11-15 | チッソ株式会社 | アクリロキシプロピルシランの製造方法 |
| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
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| ES2379101T3 (es) | 1999-12-23 | 2012-04-20 | Genentech, Inc. | Polipéptidos homólogos IL-17 y usos terapéuticos de los mismos |
| US20070160576A1 (en) | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| US20030049255A1 (en) | 2001-08-07 | 2003-03-13 | Sims John E. | Interleukin-1 receptors in the treatment of diseases |
| US7510709B2 (en) * | 2002-10-30 | 2009-03-31 | Genentech, Inc. | Method of treating inflammatory disease by inhibition of IL-17 production |
| CA2518371A1 (en) | 2003-03-14 | 2004-09-30 | Wyeth | Antibodies against human il-21 receptor and uses therefor |
| ES2354693T3 (es) | 2003-06-23 | 2011-03-17 | Genetics Institute, Llc | Anticuerpos contra interleucina-22 y usos para ellos. |
| GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| ES2551439T5 (es) | 2003-07-01 | 2018-11-08 | Ucb Biopharma Sprl | Fragmentos Fab de anticuerpos modificados |
| GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| CN101326195B9 (zh) | 2005-12-13 | 2022-11-11 | 伊莱利利公司 | 抗il-17抗体 |
-
2004
- 2004-11-16 US US10/580,164 patent/US20070269428A1/en not_active Abandoned
- 2004-11-16 JP JP2006540587A patent/JP4833850B2/ja not_active Expired - Fee Related
- 2004-11-16 EP EP15183030.4A patent/EP2974742A1/en not_active Withdrawn
- 2004-11-16 PL PL08008814T patent/PL1983000T3/pl unknown
- 2004-11-16 DK DK08008814.9T patent/DK1983000T3/en active
- 2004-11-16 WO PCT/GB2004/004850 patent/WO2005051422A1/en not_active Ceased
- 2004-11-16 CA CA2544920A patent/CA2544920C/en not_active Expired - Fee Related
- 2004-11-16 ES ES08008814.9T patent/ES2554645T3/es not_active Expired - Lifetime
- 2004-11-16 HU HUE08008814A patent/HUE026260T2/en unknown
- 2004-11-16 EP EP08008814.9A patent/EP1983000B1/en not_active Expired - Lifetime
- 2004-11-16 SI SI200432278T patent/SI1983000T1/sl unknown
- 2004-11-16 ES ES04798568T patent/ES2305879T3/es not_active Expired - Lifetime
- 2004-11-16 PT PT80088149T patent/PT1983000E/pt unknown
- 2004-11-16 DE DE602004013825T patent/DE602004013825D1/de not_active Expired - Lifetime
- 2004-11-16 AU AU2004292393A patent/AU2004292393C1/en not_active Ceased
- 2004-11-16 AT AT04798568T patent/ATE395083T1/de not_active IP Right Cessation
- 2004-11-16 EP EP04798568A patent/EP1687026B1/en not_active Revoked
-
2008
- 2008-11-24 US US12/277,030 patent/US7931900B2/en not_active Expired - Fee Related
-
2015
- 2015-11-11 HR HRP20151210TT patent/HRP20151210T1/hr unknown
- 2015-11-30 CY CY20151101086T patent/CY1116992T1/el unknown