JP2007510670A5 - - Google Patents

Download PDF

Info

Publication number
JP2007510670A5
JP2007510670A5 JP2006538530A JP2006538530A JP2007510670A5 JP 2007510670 A5 JP2007510670 A5 JP 2007510670A5 JP 2006538530 A JP2006538530 A JP 2006538530A JP 2006538530 A JP2006538530 A JP 2006538530A JP 2007510670 A5 JP2007510670 A5 JP 2007510670A5
Authority
JP
Japan
Prior art keywords
cancer
disease
thalidomide
use according
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006538530A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007510670A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/037083 external-priority patent/WO2005046593A2/en
Publication of JP2007510670A publication Critical patent/JP2007510670A/ja
Publication of JP2007510670A5 publication Critical patent/JP2007510670A5/ja
Withdrawn legal-status Critical Current

Links

JP2006538530A 2003-11-06 2004-11-04 サリドマイドを用いた、癌、及び他の疾患を治療、及び管理する方法ならびに組成物 Withdrawn JP2007510670A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51740503P 2003-11-06 2003-11-06
PCT/US2004/037083 WO2005046593A2 (en) 2003-11-06 2004-11-04 Methods and compositions using thalidomide for the treatment and management of cancers and other diseases.

Publications (2)

Publication Number Publication Date
JP2007510670A JP2007510670A (ja) 2007-04-26
JP2007510670A5 true JP2007510670A5 (https=) 2007-09-13

Family

ID=34590157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538530A Withdrawn JP2007510670A (ja) 2003-11-06 2004-11-04 サリドマイドを用いた、癌、及び他の疾患を治療、及び管理する方法ならびに組成物

Country Status (14)

Country Link
US (1) US20070208057A1 (https=)
EP (2) EP1684758A4 (https=)
JP (1) JP2007510670A (https=)
KR (1) KR20060124607A (https=)
CN (1) CN1901911A (https=)
AP (1) AP2006003637A0 (https=)
AU (1) AU2004288714A1 (https=)
BR (1) BRPI0416275A (https=)
CA (1) CA2545128C (https=)
EA (1) EA200600921A1 (https=)
IL (1) IL175427A0 (https=)
OA (1) OA13284A (https=)
WO (1) WO2005046593A2 (https=)
ZA (1) ZA200603718B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050100529A1 (en) * 2003-11-06 2005-05-12 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
ME02420B (me) 2006-09-26 2016-09-20 Celgene Corp 5-supstituirani derivati kinazolinona kao sredstva protiv raka
WO2008037257A2 (en) * 2006-09-26 2008-04-03 Genmab A/S Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
JP5070067B2 (ja) * 2007-01-15 2012-11-07 参天製薬株式会社 ＩκＢキナーゼβ阻害活性を有する新規インドール誘導体
US20090137631A1 (en) * 2007-11-22 2009-05-28 National Yang-Ming University Methods and pharmaceutical compositions for regulation of g- and/or gc-rich nucleic acid expression
CN102089281A (zh) * 2008-07-14 2011-06-08 参天制药株式会社 具有氨基甲酰基、脲基及取代氧基的新型吲哚衍生物
EP2289554A1 (en) * 2009-07-31 2011-03-02 Dafra Pharma N.V. Compositions comprising thalidomide and artemisinin for the treatment of cancer
CA2774871C (en) * 2009-10-20 2018-05-29 Tokyo Institute Of Technology Screening method utilizing thalidomide-targeting factor
US20110280849A1 (en) * 2010-03-26 2011-11-17 Anthrogenesis Corporation Tumor suppression using human placenta-derived intermediate natural killer cells and immunomodulatory compounds
US20110256236A1 (en) * 2010-04-16 2011-10-20 Erian Girgis Enhancement of the Anti-Leukemic Effect of Thalidomide
WO2011160042A2 (en) * 2010-06-18 2011-12-22 Makoto Life Sciences, Inc. Prpk-tprkb modulators and uses thereof
JP2013537172A (ja) * 2010-09-09 2013-09-30 トリフォイリウム エーピーエス 血管新生阻害剤の気道投与
JP2015500001A (ja) 2011-12-14 2015-01-05 大鵬薬品工業株式会社 組換えｐｒｐｋ−ｔｐｒｋｂ及びその使用
WO2013123620A1 (zh) * 2012-02-24 2013-08-29 Sun Yinghao Cul4A在前列腺癌诊断、治疗及预后中的用途
WO2014180882A2 (en) * 2013-05-07 2014-11-13 Universitat De Barcelona Treatment of brain metastasis from cancer
WO2015036643A2 (es) * 2013-09-13 2015-03-19 Sierra Jiménez Angels Marcador para predecir metástasis del cancer de mama
US20170304286A1 (en) * 2014-10-24 2017-10-26 Launx Biomedical Co., Ltd. New indication of paroxetine pharmaceutical composition for treating cancer
KR20190090390A (ko) * 2016-11-30 2019-08-01 인트렉손 코포레이션 스테로이드 투여 및 면역요법
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
CN113747896A (zh) * 2019-04-22 2021-12-03 斯塔顿治疗公司 来那度胺和其他免疫调节剂的连续递送
CA3204385A1 (en) 2021-01-08 2022-07-14 Rod L. Hartwig Stable solutions of immunomodulatory imide compounds for parenteral use
CN114788837B (zh) * 2022-06-07 2023-09-05 青岛东海药业有限公司 一种组合物及其在制备治疗和/或预防化疗引起的恶心呕吐的药物中的应用

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) * 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4994443A (en) 1982-12-20 1991-02-19 The Children's Medical Center Corporation Inhibition of angiogenesis
US5001116A (en) 1982-12-20 1991-03-19 The Children's Medical Center Corporation Inhibition of angiogenesis
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5391485A (en) 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5733566A (en) * 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
AU1531492A (en) 1991-02-14 1992-09-15 Rockefeller University, The Method for controlling abnormal concentration tnf alpha in human tissues
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5360352A (en) 1992-12-24 1994-11-01 The Whitaker Corporation Wire retainer for current mode coupler
US5591767A (en) * 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US6228879B1 (en) * 1997-10-16 2001-05-08 The Children's Medical Center Methods and compositions for inhibition of angiogenesis
US6114355A (en) * 1993-03-01 2000-09-05 D'amato; Robert Methods and compositions for inhibition of angiogenesis
US5629327A (en) * 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
US20010056114A1 (en) * 2000-11-01 2001-12-27 D'amato Robert Methods for the inhibition of angiogenesis with 3-amino thalidomide
US5698579A (en) * 1993-07-02 1997-12-16 Celgene Corporation Cyclic amides
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5643915A (en) 1995-06-06 1997-07-01 Andrulis Pharmaceuticals Corp. Treatment of ischemia/reperfusion injury with thalidomide alone or in combination with other therapies
US5731325A (en) * 1995-06-06 1998-03-24 Andrulis Pharmaceuticals Corp. Treatment of melanomas with thalidomide alone or in combination with other anti-melanoma agents
HU228769B1 (en) * 1996-07-24 2013-05-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
US6281230B1 (en) * 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
US5798368A (en) * 1996-08-22 1998-08-25 Celgene Corporation Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNFα levels
US5635517B1 (en) * 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
NZ334148A (en) * 1996-08-12 2001-12-21 Celgene Corp 3-Substituted phenyl-ethyl or ethenyl derivatives terminated with a nitrile, alkane, carboxyl or carbamoyl group useful to reduce cytokine levels
ATE493983T1 (de) * 1996-11-05 2011-01-15 Childrens Medical Center Thalidomide und dexamethason für die behandlung von tumors
US5955476A (en) * 1997-11-18 1999-09-21 Celgene Corporation Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
US5874448A (en) * 1997-11-18 1999-02-23 Celgene Corporation Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels
TR200101502T2 (tr) * 1998-03-16 2002-06-21 Celgene Corporation 2-(2,6-dioksopiperidin-3-il) izoindolin türevleri, bunların hazırlanması ve enflamatuar sitokinlerin inhibitörleri olarak kullanımı
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
US20030013739A1 (en) * 1998-12-23 2003-01-16 Pharmacia Corporation Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
CN1342146A (zh) * 1999-03-18 2002-03-27 塞尔基因公司 取代的1－氧代－和1,3－二氧代异吲哚啉及其在用于减少炎性细胞因子含量的药物组合物中的用途
US7182953B2 (en) * 1999-12-15 2007-02-27 Celgene Corporation Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders
US6326388B1 (en) * 1999-12-21 2001-12-04 Celgene Corporation Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level
CA2319872C (en) * 2000-02-02 2012-06-19 Chun-Ying Huang Pharmaceutical composition for the treatment of hepatocellular carcinoma
KR20030003708A (ko) * 2000-03-31 2003-01-10 셀진 코포레이션 시클로옥시게나제-2 활성의 저해
EP1676577A1 (en) * 2000-05-15 2006-07-05 Celgene Corporation Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide
EP1286671B1 (en) * 2000-05-15 2006-04-05 Celgene Corporation Compositions for the treatment of colorectal cancer comprising thalidomide and irinotecan
AU2001261474B2 (en) * 2000-05-15 2006-03-09 Celgene Corporation Compositions and methods for the treatment of cancer
US6458810B1 (en) * 2000-11-14 2002-10-01 George Muller Pharmaceutically active isoindoline derivatives
US20020128228A1 (en) * 2000-12-01 2002-09-12 Wen-Jen Hwu Compositions and methods for the treatment of cancer
US20030045552A1 (en) * 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
US7091353B2 (en) * 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
US7320991B2 (en) * 2001-02-27 2008-01-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Analogs of thalidomide as potential angiogenesis inhibitors
NZ531294A (en) * 2001-08-06 2005-11-25 Childrens Medical Center Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
WO2004009776A2 (en) * 2002-07-19 2004-01-29 Abbott Biotechnology Ltd. TREATMENT OF TNFα RELATED DISORDERS
US20040091455A1 (en) * 2002-10-31 2004-05-13 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
US7563810B2 (en) * 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
CL2004001004A1 (es) * 2003-05-19 2005-03-18 Upjohn Co Combinacion farmaceutica que comprende irinotecan y revimid para tratar el mieloma multiple.

Similar Documents

Publication Publication Date Title
JP2007510670A5 (https=)
CA2486141A1 (en) Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
JP2006508131A5 (https=)
RU2348407C2 (ru) Способы и композиции с использованием иммуномодулирующих соединений для лечения и поддержания состояния при раке и других заболеваниях
US11174256B2 (en) Imidazopyridine derivatives
CA2545128A1 (en) Methods and compositions using thalidomide for the treatment and management of cancers and other diseases
AU2013299627B2 (en) Methods of treating cancer using 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
EP1389203B1 (en) Analogs of thalidomide as angiogenesis inhibitors
JP2008508298A5 (https=)
ZA200409387B (en) Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
US20210137955A1 (en) Combination therapy for cancer treatment
US8969381B2 (en) Chemokine CXCR4 receptor modulators and used related thereto
JP7611855B2 (ja) ユーイング肉腫治療用キノリン系化合物又はその薬学的に許容される塩
CN113786409B (zh) 包含磷酸肌醇3-激酶抑制剂和第二抗增殖剂的组合物
CN115698014B (zh) 用于治疗医学病症的细胞周期蛋白依赖性激酶抑制化合物
KR20070047807A (ko) 이소인돌린 화합물 및 그의 사용 방법
WO2019136244A1 (en) Heterocyclic compounds for the treatment of abnormal cellular proliferation
CN117957000A (zh) 药物组合物及其用途
CN112043702A (zh) 用于联合治疗结直肠癌的喹啉类化合物
Cho et al. Design, docking, and synthesis of novel indeno [1, 2-c] isoquinolines for the development of antitumor agents as topoisomerase I inhibitors
CN119403808A (zh) 用于医学治疗的细胞周期蛋白依赖性激酶2抑制剂
WO2022083657A1 (zh) 取代苯并或吡啶并嘧啶胺类抑制剂及其制备方法和应用
WO2019222521A1 (en) Cdk inhibitors for the treatment of neoplastic disorders
TWI753229B (zh) 用於治療癌症之組合療法
CN115515596A (zh) 包含三并环类化合物的组合及其在制备治疗hbv药物中的应用