|
ATE75483T1
(de)
|
1981-10-23 |
1992-05-15 |
Molecular Biosystems Inc |
Oligonukleotides heilmittel und dessen herstellungsverfahren.
|
|
US4541087A
(en)
*
|
1983-06-27 |
1985-09-10 |
Confertech International, Inc. |
Digital teleconferencing control device, system and method
|
|
CA1339596C
(en)
|
1987-08-07 |
1997-12-23 |
New England Medical Center Hospitals, Inc. |
Viral expression inhibitors
|
|
US4958013A
(en)
*
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
US5399676A
(en)
*
|
1989-10-23 |
1995-03-21 |
Gilead Sciences |
Oligonucleotides with inverted polarity
|
|
EP0468520A3
(en)
|
1990-07-27 |
1992-07-01 |
Mitsui Toatsu Chemicals, Inc. |
Immunostimulatory remedies containing palindromic dna sequences
|
|
WO1994002499A1
(en)
*
|
1992-07-27 |
1994-02-03 |
Hybridon, Inc. |
Oligonucleotide alkylphosphonothioates
|
|
US5558988A
(en)
*
|
1992-11-13 |
1996-09-24 |
Thomas Jefferson University |
Primers and methods for detecting mutations in the procollagen II gene that indicate a genetic predisposition for osteoarthritis
|
|
US6605708B1
(en)
|
1993-07-28 |
2003-08-12 |
Hybridon, Inc. |
Building blocks with carbamate internucleoside linkages and oligonucleotides derived therefrom
|
|
DE4338704A1
(de)
*
|
1993-11-12 |
1995-05-18 |
Hoechst Ag |
Stabilisierte Oligonucleotide und deren Verwendung
|
|
US5646126A
(en)
*
|
1994-02-28 |
1997-07-08 |
Epoch Pharmaceuticals |
Sterol modified oligonucleotide duplexes having anticancer activity
|
|
US5596091A
(en)
*
|
1994-03-18 |
1997-01-21 |
The Regents Of The University Of California |
Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides
|
|
US6727230B1
(en)
*
|
1994-03-25 |
2004-04-27 |
Coley Pharmaceutical Group, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US6239116B1
(en)
*
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6207646B1
(en)
*
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US7935675B1
(en)
|
1994-07-15 |
2011-05-03 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US20030026782A1
(en)
*
|
1995-02-07 |
2003-02-06 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
|
US6429199B1
(en)
*
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US20030050263A1
(en)
*
|
1994-07-15 |
2003-03-13 |
The University Of Iowa Research Foundation |
Methods and products for treating HIV infection
|
|
DE69535905D1
(de)
|
1994-07-15 |
2009-02-26 |
Coley Pharm Group Inc |
Immunomodulatorische Oligonukleotide
|
|
DE19502912A1
(de)
|
1995-01-31 |
1996-08-01 |
Hoechst Ag |
G-Cap Stabilisierte Oligonucleotide
|
|
US5968909A
(en)
|
1995-08-04 |
1999-10-19 |
Hybridon, Inc. |
Method of modulating gene expression with reduced immunostimulatory response
|
|
US5780448A
(en)
*
|
1995-11-07 |
1998-07-14 |
Ottawa Civic Hospital Loeb Research |
DNA-based vaccination of fish
|
|
US7432048B2
(en)
*
|
1996-11-29 |
2008-10-07 |
Third Wave Technologies, Inc. |
Reactions on a solid surface
|
|
US6030955A
(en)
*
|
1996-03-21 |
2000-02-29 |
The Trustees Of Columbia University In The City Of New York And Imclone Systems, Inc. |
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof
|
|
US5856462A
(en)
|
1996-09-10 |
1999-01-05 |
Hybridon Incorporated |
Oligonucleotides having modified CpG dinucleosides
|
|
EP0930893B1
(en)
|
1996-10-11 |
2005-04-13 |
The Regents of The University of California |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
|
EP0855184A1
(en)
*
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
|
AU738513B2
(en)
*
|
1997-02-28 |
2001-09-20 |
University Of Iowa Research Foundation, The |
Use of nucleic acids containing unmethylated CpG dinucleotide in the treatment of LPS-associated disorders
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6426334B1
(en)
|
1997-04-30 |
2002-07-30 |
Hybridon, Inc. |
Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal
|
|
US6835395B1
(en)
|
1997-05-14 |
2004-12-28 |
The University Of British Columbia |
Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles
|
|
WO1998052581A1
(en)
*
|
1997-05-20 |
1998-11-26 |
Ottawa Civic Hospital Loeb Research Institute |
Vectors and methods for immunization or therapeutic protocols
|
|
JP4101888B2
(ja)
|
1997-06-06 |
2008-06-18 |
ダイナバックス テクノロジーズ コーポレイション |
免疫刺激オリゴヌクレオチド、その組成物およびその使用方法
|
|
US6589940B1
(en)
*
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
US20040006034A1
(en)
*
|
1998-06-05 |
2004-01-08 |
Eyal Raz |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
WO1999001154A1
(en)
|
1997-07-03 |
1999-01-14 |
University Of Iowa Research Foundation |
Method for inhibiting immunostimulatory dna associated responses
|
|
DE19750702A1
(de)
*
|
1997-11-15 |
1999-05-27 |
Hoechst Marion Roussel De Gmbh |
Antisense Oligonucleotide gegen Tenascin zur Behandlung von Vitiligo
|
|
US7393630B2
(en)
*
|
1997-12-16 |
2008-07-01 |
Novartis Vaccines And Diagnostics, Inc. |
Use of microparticles combined with submicron oil-in-water emulsions
|
|
JP2002510644A
(ja)
|
1998-04-03 |
2002-04-09 |
ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
免疫治療用オリゴヌクレオチドおよびサイトカインを用いる免疫系刺激のための方法および産物
|
|
ATE302269T1
(de)
*
|
1998-04-14 |
2005-09-15 |
Sugen Inc |
Ste20-verwandte proteinkinasen
|
|
EP1595946A3
(en)
*
|
1998-04-14 |
2006-01-11 |
Sugen, Inc. |
STE20-related protein kinases
|
|
EP1077708A1
(en)
|
1998-05-06 |
2001-02-28 |
University Of Iowa Research Foundation |
Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
|
|
CA2328406A1
(en)
|
1998-05-14 |
1999-11-18 |
Hermann Wagner |
Methods for regulating hematopoiesis using cpg-oligonucleotides
|
|
IL139813A0
(en)
|
1998-05-22 |
2002-02-10 |
Loeb Health Res Inst At The Ot |
Methods and products for inducing mucosal immunity
|
|
US6562798B1
(en)
*
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
WO2000006588A1
(en)
|
1998-07-27 |
2000-02-10 |
University Of Iowa Research Foundation |
STEREOISOMERS OF CpG OLIGONUCLEOTIDES AND RELATED METHODS
|
|
CA2839037A1
(en)
*
|
1998-08-20 |
2000-03-02 |
E.I. Du Pont De Nemours And Company |
Genes for plant fatty acid modifying enzymes associated with conjugated double bond formation
|
|
FR2783170B1
(fr)
|
1998-09-11 |
2004-07-16 |
Pasteur Merieux Serums Vacc |
Emulsion immunostimulante
|
|
AU1915500A
(en)
*
|
1998-11-20 |
2000-06-13 |
Bristol-Myers Squibb Company |
Water soluble prodrugs of azole compounds
|
|
US6207819B1
(en)
*
|
1999-02-12 |
2001-03-27 |
Isis Pharmaceuticals, Inc. |
Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds
|
|
WO2000054803A2
(en)
|
1999-03-16 |
2000-09-21 |
Panacea Pharmaceuticals, Llc |
Immunostimulatory nucleic acids and antigens
|
|
EP1176966B1
(en)
*
|
1999-04-12 |
2013-04-03 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Oligodeoxynucleotide and its use to induce an immune response
|
|
US6977245B2
(en)
*
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
EP1377554A1
(en)
|
1999-06-16 |
2004-01-07 |
University Of Iowa Research Foundation |
Antagonism of immunostimulatory cpg-oligonucleotides by 4-aminoquinolines and other weak bases
|
|
US6514948B1
(en)
*
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
|
DE19935756A1
(de)
*
|
1999-07-27 |
2001-02-08 |
Mologen Forschungs Entwicklung |
Kovalent geschlossenes Nukleinsäuremolekül zur Immunstimulation
|
|
DE19935302A1
(de)
*
|
1999-07-28 |
2001-02-08 |
Aventis Pharma Gmbh |
Konjugate und Verfahren zu deren Herstellung sowie deren Verwendung zum Transport von Molekülen über biologische Membranen
|
|
US6822086B1
(en)
*
|
1999-08-09 |
2004-11-23 |
The General Hospital Corporation |
Drug-carrier complexes and methods of use thereof
|
|
JP5268214B2
(ja)
|
1999-08-13 |
2013-08-21 |
イデラ ファーマシューティカルズ インコーポレイテッド |
ヌクレオシドの位置的修飾によるオリゴヌクレオチドＣｐＧ−媒体免疫刺激の変調
|
|
TR200200797T2
(tr)
|
1999-09-25 |
2002-10-21 |
University Of Iowa Research Foundation |
İmmünostimülatör nükleik asitler
|
|
US6949520B1
(en)
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
|
DE60131430T2
(de)
*
|
2000-01-14 |
2008-10-16 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
|
|
WO2001095935A1
(en)
|
2000-01-20 |
2001-12-20 |
Ottawa Health Research Institute |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
|
AU783687B2
(en)
|
2000-01-26 |
2005-11-24 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7585847B2
(en)
|
2000-02-03 |
2009-09-08 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for the treatment of asthma and allergy
|
|
US20020156033A1
(en)
|
2000-03-03 |
2002-10-24 |
Bratzler Robert L. |
Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer
|
|
US20040131628A1
(en)
*
|
2000-03-08 |
2004-07-08 |
Bratzler Robert L. |
Nucleic acids for the treatment of disorders associated with microorganisms
|
|
JP3585420B2
(ja)
*
|
2000-04-20 |
2004-11-04 |
株式会社椿本チエイン |
チェーン用巻き加工品及びその製造方法
|
|
AU2001259706A1
(en)
|
2000-05-09 |
2001-11-20 |
Reliable Biopharmaceutical, Inc. |
Polymeric compounds useful as prodrugs
|
|
US6339630B1
(en)
*
|
2000-05-18 |
2002-01-15 |
The United States Of America As Represented By The United States Department Of Energy |
Sealed drive screw operator
|
|
WO2001097843A2
(en)
*
|
2000-06-22 |
2001-12-27 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
US20020165178A1
(en)
|
2000-06-28 |
2002-11-07 |
Christian Schetter |
Immunostimulatory nucleic acids for the treatment of anemia, thrombocytopenia, and neutropenia
|
|
US20020198165A1
(en)
|
2000-08-01 |
2002-12-26 |
Bratzler Robert L. |
Nucleic acids for the prevention and treatment of gastric ulcers
|
|
US20020091097A1
(en)
*
|
2000-09-07 |
2002-07-11 |
Bratzler Robert L. |
Nucleic acids for the prevention and treatment of sexually transmitted diseases
|
|
CA2419894A1
(en)
*
|
2000-09-15 |
2002-03-21 |
Coley Pharmaceutical Gmbh |
Process for high throughput screening of cpg-based immuno-agonist/antagonist
|
|
JP2004509970A
(ja)
*
|
2000-09-26 |
2004-04-02 |
ハイブリドン・インコーポレイテッド |
位置的化学変化による免疫刺激オリゴヌクレオチドアナログの免疫刺激活性の調節
|
|
FR2814958B1
(fr)
*
|
2000-10-06 |
2003-03-07 |
Aventis Pasteur |
Composition vaccinale
|
|
GB0025577D0
(en)
*
|
2000-10-18 |
2000-12-06 |
Smithkline Beecham Biolog |
Vaccine
|
|
AU2001297693A1
(en)
|
2000-12-08 |
2002-09-12 |
Coley Pharmaceutical Gmbh |
Cpg-like nucleic acids and methods of use thereof
|
|
US20030055014A1
(en)
*
|
2000-12-14 |
2003-03-20 |
Bratzler Robert L. |
Inhibition of angiogenesis by nucleic acids
|
|
US20030050268A1
(en)
*
|
2001-03-29 |
2003-03-13 |
Krieg Arthur M. |
Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases
|
|
US20030052063A1
(en)
*
|
2001-03-30 |
2003-03-20 |
Motoaki Sakashita |
Decontamination method and apparatus
|
|
US7713942B2
(en)
*
|
2001-04-04 |
2010-05-11 |
Nordic Vaccine Technology A/S |
Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
|
|
US7105495B2
(en)
|
2001-04-30 |
2006-09-12 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7785610B2
(en)
*
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
|
US20040132677A1
(en)
*
|
2001-06-21 |
2004-07-08 |
Fearon Karen L. |
Chimeric immunomodulatory compounds and methods of using the same-IV
|
|
US8114418B2
(en)
|
2001-06-21 |
2012-02-14 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—IV
|
|
US6893572B2
(en)
*
|
2001-07-12 |
2005-05-17 |
Western Environmental Engineering Company |
Solids accumulating flotation separator
|
|
US7666674B2
(en)
*
|
2001-07-27 |
2010-02-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
|
|
WO2003040308A2
(en)
*
|
2001-07-27 |
2003-05-15 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver cpg oligonucleotides in vivo
|
|
WO2003012061A2
(en)
|
2001-08-01 |
2003-02-13 |
Coley Pharmaceutical Gmbh |
Methods and compositions relating to plasmacytoid dendritic cells
|
|
AU2002361468A1
(en)
*
|
2001-08-14 |
2003-03-18 |
The Government Of The United States Of America As Represented By The Secretary Of Health And Human S |
Method for rapid generation of mature dendritic cells
|
|
CN1604795B
(zh)
|
2001-08-17 |
2010-05-26 |
科勒制药股份公司 |
具有提高的活性的组合基序免疫刺激寡肽
|
|
EP1429143A4
(en)
*
|
2001-08-22 |
2006-04-12 |
Inst Antibodies Co Ltd |
SELECTION PROCEDURE FOR BINDING MOLECULES
|
|
JP2005523878A
(ja)
*
|
2001-09-28 |
2005-08-11 |
パーデュー・リサーチ・ファウンデーション |
リガンド・免疫原物質複合体を用いた処置方法
|
|
WO2003031573A2
(en)
|
2001-10-05 |
2003-04-17 |
Coley Pharmaceutical Gmbh |
Toll-like receptor 3 signaling agonists and antagonists
|
|
US20030139364A1
(en)
*
|
2001-10-12 |
2003-07-24 |
University Of Iowa Research Foundation |
Methods and products for enhancing immune responses using imidazoquinoline compounds
|
|
US7276489B2
(en)
*
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
AU2002366710A1
(en)
*
|
2001-12-20 |
2003-07-09 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of |
USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS
|
|
JP2005526497A
(ja)
|
2002-02-04 |
2005-09-08 |
ビオミラ，インコーポレーテッド |
免疫刺激性、共有結合性脂質化オリゴヌクレオチド
|
|
AU2003230806B2
(en)
|
2002-04-04 |
2009-05-07 |
Zoetis Belgium S.A. |
Immunostimulatory G,U-containing oligoribonucleotides
|
|
MXPA04010415A
(es)
*
|
2002-04-22 |
2005-02-17 |
Bioniche Life Sciences Inc |
Composiciones oligonucleotdias y su uso para la modulacion de respuestas inmunes.
|
|
ATE411815T1
(de)
|
2002-05-10 |
2008-11-15 |
Tekmira Pharmaceuticals Corp |
Methylierte immunstimulierende oligodeoxynukleotide und verfahren zu deren verwendung
|
|
AU2003243409A1
(en)
*
|
2002-06-05 |
2003-12-22 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory cpg nucleic acids
|
|
US7576066B2
(en)
*
|
2002-07-03 |
2009-08-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7569553B2
(en)
*
|
2002-07-03 |
2009-08-04 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US20040053880A1
(en)
*
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7807803B2
(en)
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7605138B2
(en)
|
2002-07-03 |
2009-10-20 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
WO2004007743A2
(en)
|
2002-07-17 |
2004-01-22 |
Coley Pharmaceutical Gmbh |
Use of cpg nucleic acids in prion-disease
|
|
SG172476A1
(en)
*
|
2002-08-12 |
2011-07-28 |
Dynavax Tech Corp |
Immunomodulatory compositions comprising a cationic condensing agent, an immunostimulatory compound comprising 5'-cg-3', an a non ionic detergent
|
|
AR040996A1
(es)
*
|
2002-08-19 |
2005-04-27 |
Coley Pharm Group Inc |
Acidos nucleicos inmunoestimuladores
|
|
US8043622B2
(en)
*
|
2002-10-08 |
2011-10-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides
|
|
CN1753687A
(zh)
*
|
2002-10-29 |
2006-03-29 |
科勒制药集团股份有限公司 |
Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用
|
|
AU2003304107B2
(en)
*
|
2002-11-01 |
2008-05-15 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of preventing infections from bioterrorism agents with immunostimulatory CpG oligonucleotides
|
|
WO2004053104A2
(en)
|
2002-12-11 |
2004-06-24 |
Coley Pharmaceutical Group, Inc. |
5’ cpg nucleic acids and methods of use
|
|
JP2006516099A
(ja)
*
|
2002-12-23 |
2006-06-22 |
ダイナバックス テクノロジーズ コーポレイション |
分枝状の免疫調節化合物及び該化合物の使用方法
|
|
KR101123489B1
(ko)
|
2003-01-16 |
2012-03-28 |
이데라 파마슈티칼즈, 인코포레이티드 |
개질된 면역자극성 디뉴클레오티드를 이용한 올리고뉴클레오티드-기재 화합물의 면역자극 특성의 조절
|
|
EP1608403A2
(en)
*
|
2003-04-02 |
2005-12-28 |
Coley Pharmaceutical Group, Ltd. |
Immunostimulatory nucleic acid oil-in-water formulations for topical application
|
|
WO2004094671A2
(en)
|
2003-04-22 |
2004-11-04 |
Coley Pharmaceutical Gmbh |
Methods and products for identification and assessment of tlr ligands
|
|
CN102604957B
(zh)
*
|
2003-06-11 |
2015-10-07 |
艾德拉药物股份有限公司 |
稳定的免疫调节寡核苷酸
|
|
EA200600069A1
(ru)
*
|
2003-06-20 |
2006-08-25 |
Коли Фармасьютикал Гмбх |
Низкомолекулярные антагонисты toll-подобных рецепторов (tlr)
|
|
MXPA06000619A
(es)
*
|
2003-07-15 |
2006-04-11 |
Hybridon Inc |
Estimulacion sinergistica del sistema inmune usando oligonucleotidos inmunoestimuladores y/o compuestos inmunomeros en conjunto con citocinas y/o agentes quimioterapeuticos o terapia de radiacion.
|
|
ES2342069T4
(es)
*
|
2003-09-05 |
2011-01-26 |
Anadys Pharmaceuticals, Inc. |
Ligandos de tlr7 para el tratamiento de la hepatitis c.
|
|
AU2004275876B2
(en)
|
2003-09-25 |
2011-03-31 |
Coley Pharmaceutical Gmbh |
Nucleic acid-lipophilic conjugates
|
|
US20050215501A1
(en)
|
2003-10-24 |
2005-09-29 |
Coley Pharmaceutical Group, Inc. |
Methods and products for enhancing epitope spreading
|
|
SG122973A1
(en)
*
|
2003-10-30 |
2006-06-29 |
Coley Pharm Gmbh |
C-class oligonucleotide analogs with enhanced immunostimulatory potency
|
|
US20050100983A1
(en)
*
|
2003-11-06 |
2005-05-12 |
Coley Pharmaceutical Gmbh |
Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLR9) signaling
|
|
KR101138131B1
(ko)
*
|
2003-12-08 |
2012-04-23 |
이데라 파마슈티칼즈, 인코포레이티드 |
작은 올리고뉴클레오티드-기초 화합물에 의한 면역자극특성의 조절
|
|
CA2567789A1
(en)
*
|
2004-06-08 |
2006-08-03 |
Coley Pharmaceutical Gmbh |
Abasic oligonucleotide as carrier platform for antigen and immunostimulatory agonist and antagonist
|
|
NZ552522A
(en)
*
|
2004-06-15 |
2009-04-30 |
Idera Pharmaceuticals Inc |
Immunostimulatory oligonucleotide multimers
|
|
EP1776105A2
(en)
*
|
2004-07-18 |
2007-04-25 |
Coley Pharmaceutical Group, Ltd |
Methods and compositions for inducing innate immune responses
|
|
MY159370A
(en)
*
|
2004-10-20 |
2016-12-30 |
Coley Pharm Group Inc |
Semi-soft-class immunostimulatory oligonucleotides
|
|
EP1829887B1
(en)
*
|
2004-11-29 |
2011-08-24 |
Changchun Huapu Biotechnology Co., Ltd. |
Cpg single-strand deoxynucleotides for use as adjuvant
|
|
CN1810970B
(zh)
*
|
2005-01-27 |
2011-05-18 |
长春华普生物技术有限公司 |
含CpG的单链脱氧核苷酸与其疫苗组合物及其应用
|
|
CN1847256B
(zh)
*
|
2005-04-13 |
2011-06-15 |
长春华普生物技术有限公司 |
含CpG单链脱氧寡核苷酸和利巴韦林联合应用产生的抗病毒作用
|
|
US7792535B2
(en)
*
|
2005-05-31 |
2010-09-07 |
Alcatel-Lucent Usa Inc. |
Enhanced mobile station paging in a wireless telecommunications network
|
|
US20090117132A1
(en)
*
|
2005-07-07 |
2009-05-07 |
Pfizer, Inc. |
Anti-Ctla-4 Antibody and Cpg-Motif-Containing Synthetic Oligodeoxynucleotide Combination Therapy for Cancer Treatment
|
|
US7965675B2
(en)
*
|
2005-08-22 |
2011-06-21 |
Motorola Mobility, Inc. |
System and method for detecting an unlicensed mobile alliance (UMA) service in GSM wireless communication networks
|
|
EP1929014B1
(en)
*
|
2005-08-31 |
2014-08-13 |
The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services |
Methods of altering an immune response induced by d-type cpg oligodeoxynucleotides
|
|
US8399423B2
(en)
*
|
2005-10-12 |
2013-03-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
US7662949B2
(en)
*
|
2005-11-25 |
2010-02-16 |
Coley Pharmaceutical Gmbh |
Immunostimulatory oligoribonucleotides
|
|
DK1991678T4
(da)
*
|
2006-02-15 |
2020-10-19 |
Rechtsanwalt Thomas Beck |
Sammensætninger og fremgangsmåder til oligonukleotid-formuleringer
|
|
KR101221589B1
(ko)
*
|
2006-04-07 |
2013-01-15 |
이데라 파마슈티칼즈, 인코포레이티드 |
Ｔｌｒ７ 및 ｔｌｒ８에 대한 안정화된 면역 조절성 ｒｎａ〔ｓｉｍｒａ〕 화합물
|
|
KR101251707B1
(ko)
*
|
2006-09-27 |
2013-04-11 |
콜리 파마슈티칼 게엠베하 |
면역 자극 활성이 증강된 소수성 Ｔ 유사체를 함유하는 ＣｐＧ 올리고뉴클레오티드 유사체
|
|
US8377898B2
(en)
*
|
2006-10-12 |
2013-02-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
RU2009125599A
(ru)
*
|
2006-12-04 |
2011-01-20 |
Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Иллинойс (Us) |
Композиции и способы лечения рака cpg-богатой днк и купредоксинами
|
|
JP5563455B2
(ja)
*
|
2007-08-01 |
2014-07-30 |
イデラ ファーマシューティカルズ インコーポレイテッド |
Ｔｌｒ９の新規な合成アゴニスト
|
|
WO2009022215A1
(en)
*
|
2007-08-13 |
2009-02-19 |
Pfizer Inc. |
Combination motif immune stimulatory oligonucleotides with improved activity
|
|
JP5753382B2
(ja)
*
|
2007-11-06 |
2015-07-22 |
アディウティーダ ファーマシューティカルズ ゲーエムベーハー |
修飾されたオリゴリン酸基を含有する免疫賦活オリゴリボヌクレオチドアナログ
|
|
CA2742531A1
(en)
*
|
2008-11-04 |
2010-05-14 |
Idera Pharmaceuticals, Inc. |
Modulation of toll-like receptor 5 expression by antisense oligonucleotides
|