JP2007505858A - 増殖性障害の処置に有用な２，４−ジ（フェニルアミノ）ピリミジン - Google Patents
増殖性障害の処置に有用な２，４−ジ（フェニルアミノ）ピリミジン Download PDFInfo
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- JP2007505858A JP2007505858A JP2006526595A JP2006526595A JP2007505858A JP 2007505858 A JP2007505858 A JP 2007505858A JP 2006526595 A JP2006526595 A JP 2006526595A JP 2006526595 A JP2006526595 A JP 2006526595A JP 2007505858 A JP2007505858 A JP 2007505858A
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- alkyl
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- cycloalkyl
- aryl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
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- Inorganic Chemistry (AREA)
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- Dermatology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50437403P | 2003-09-18 | 2003-09-18 | |
| PCT/EP2004/010466 WO2005026130A1 (en) | 2003-09-18 | 2004-09-17 | 2,4-di (phenylamino) pyrimidines useful in the treatment of proliferative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007505858A true JP2007505858A (ja) | 2007-03-15 |
| JP2007505858A5 JP2007505858A5 (cg-RX-API-DMAC7.html) | 2007-11-08 |
Family
ID=34312463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006526595A Pending JP2007505858A (ja) | 2003-09-18 | 2004-09-17 | 増殖性障害の処置に有用な２，４−ジ（フェニルアミノ）ピリミジン |
Country Status (9)
| Country | Link |
|---|---|
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- 2004-09-17 JP JP2006526595A patent/JP2007505858A/ja active Pending
- 2004-09-17 US US10/571,733 patent/US20070105839A1/en not_active Abandoned
- 2004-09-17 EP EP04765358A patent/EP1663992A1/en not_active Withdrawn
- 2004-09-17 MX MXPA06003054A patent/MXPA06003054A/es not_active Application Discontinuation
- 2004-09-17 CN CN200480026942A patent/CN100584832C/zh not_active Expired - Fee Related
- 2004-09-17 BR BRPI0414544-5A patent/BRPI0414544A/pt not_active IP Right Cessation
- 2004-09-17 CA CA002538413A patent/CA2538413A1/en not_active Abandoned
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Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2007502260A (ja) * | 2003-08-15 | 2007-02-08 | ノバルティス アクチエンゲゼルシャフト | 新生物疾患、炎症および免疫障害の処置に有用な２，４−ピリミジンジアミン |
| JP2010524952A (ja) * | 2007-04-16 | 2010-07-22 | ハッチソン メディファーマ エンタープライジズ リミテッド | ピリミジン誘導体 |
| JP2011526291A (ja) * | 2008-06-25 | 2011-10-06 | アイアールエム・リミテッド・ライアビリティ・カンパニー | キナーゼ阻害剤としてのピリミジン誘導体 |
| JP2011526284A (ja) * | 2008-06-25 | 2011-10-06 | アイアールエム・リミテッド・ライアビリティ・カンパニー | キナーゼ阻害剤としてのピリミジン誘導体 |
| JP2017137352A (ja) * | 2008-06-27 | 2017-08-10 | セルジーン アビロミクス リサーチ， インコーポレイテッド | ヘテロアリール化合物およびそれらの使用 |
| JP2011526299A (ja) * | 2008-06-27 | 2011-10-06 | アビラ セラピューティクス， インコーポレイテッド | ヘテロアリール化合物およびそれらの使用 |
| JP2014208674A (ja) * | 2008-06-27 | 2014-11-06 | セルジーン アビロミクス リサーチ， インコーポレイテッド | ヘテロアリール化合物およびそれらの使用 |
| JP2019194235A (ja) * | 2008-06-27 | 2019-11-07 | セルジーン シーエーアール エルエルシー | ヘテロアリール化合物およびそれらの使用 |
| JP2012510481A (ja) * | 2008-12-01 | 2012-05-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌に対するオータキシン阻害剤としての２，５−ジアミノ−置換ピリド［４，３−ｄ］ピリミジン |
| JP2013515786A (ja) * | 2009-12-29 | 2013-05-09 | アビラ セラピューティクス， インコーポレイテッド | ヘテロアリール化合物およびそれらの使用 |
| JP2015528440A (ja) * | 2012-08-10 | 2015-09-28 | コーリア リサーチ インスティテュート オブ ケミカル テクノロジー | Ｎ２，ｎ４−ビス（４−（ピペラジン−１−イル）フェニル）ピリミジン−２，４−ジアミン誘導体又は薬学的に許容されるその塩、及び有効成分としてこの誘導体又は塩を含有する癌を予防又は処置するための組成物 |
| JP2016513661A (ja) * | 2013-03-14 | 2016-05-16 | トレロ ファーマシューティカルズ， インコーポレイテッド | Ｊａｋ２およびａｌｋ２阻害剤およびその使用方法 |
| JP2020125354A (ja) * | 2013-03-14 | 2020-08-20 | トレロ ファーマシューティカルズ， インコーポレイテッド | Ｊａｋ２およびａｌｋ２阻害剤およびその使用方法 |
| US10752594B2 (en) | 2013-03-14 | 2020-08-25 | Sumitomo Dainippon Pharma Oncology, Inc. | JAK1 and ALK2 inhibitors and methods for their use |
| JP2021500334A (ja) * | 2017-10-18 | 2021-01-07 | エピザイム，インコーポレイティド | Ｅｈｍｔ２阻害剤としてのアミン置換複素環化合物、その塩、及びそれらの合成方法 |
| US11040038B2 (en) | 2018-07-26 | 2021-06-22 | Sumitomo Dainippon Pharma Oncology, Inc. | Methods for treating diseases associated with abnormal ACVR1 expression and ACVR1 inhibitors for use in the same |
| JP2023528170A (ja) * | 2020-06-08 | 2023-07-04 | 南京紅云生物科技有限公司 | アルケニルピリミジン系化合物、その調製方法及び使用 |
| US12679822B2 (en) | 2020-06-08 | 2026-07-14 | Hongyun Biotech Co., Ltd. | Alkenyl pyrimidine compound, preparation method therefor, and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US20070105839A1 (en) | 2007-05-10 |
| WO2005026130A1 (en) | 2005-03-24 |
| CN1852900A (zh) | 2006-10-25 |
| BRPI0414544A (pt) | 2006-11-07 |
| AU2004272288B2 (en) | 2008-11-13 |
| EP1663992A1 (en) | 2006-06-07 |
| CA2538413A1 (en) | 2005-03-24 |
| AU2004272288A1 (en) | 2005-03-24 |
| CN100584832C (zh) | 2010-01-27 |
| MXPA06003054A (es) | 2006-05-31 |
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