JP2007505164A5 - - Google Patents

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Publication number
JP2007505164A5
JP2007505164A5 JP2006533682A JP2006533682A JP2007505164A5 JP 2007505164 A5 JP2007505164 A5 JP 2007505164A5 JP 2006533682 A JP2006533682 A JP 2006533682A JP 2006533682 A JP2006533682 A JP 2006533682A JP 2007505164 A5 JP2007505164 A5 JP 2007505164A5
Authority
JP
Japan
Prior art keywords
trifluoroethyl
amino
nitro
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006533682A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007505164A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/018456 external-priority patent/WO2004110978A2/en
Publication of JP2007505164A publication Critical patent/JP2007505164A/ja
Publication of JP2007505164A5 publication Critical patent/JP2007505164A5/ja
Pending legal-status Critical Current

Links

JP2006533682A 2003-06-10 2004-06-09 アンドロゲン、グルココルチコイド、ミネラルコルチコイドおよびプロゲステロン受容体のモジュレーターとしての１−アミノナフタレン類 Pending JP2007505164A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47725603P 2003-06-10 2003-06-10
PCT/US2004/018456 WO2004110978A2 (en) 2003-06-10 2004-06-09 1-aminonaphthalenes as modulators of androgen, glucocorticoid, mineralocorticoid and progesterone receptors

Publications (2)

Publication Number Publication Date
JP2007505164A JP2007505164A (ja) 2007-03-08
JP2007505164A5 true JP2007505164A5 (https=) 2007-07-26

Family

ID=33551695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006533682A Pending JP2007505164A (ja) 2003-06-10 2004-06-09 アンドロゲン、グルココルチコイド、ミネラルコルチコイドおよびプロゲステロン受容体のモジュレーターとしての１−アミノナフタレン類

Country Status (4)

Country Link
US (1) US20060142387A1 (https=)
EP (1) EP1636167A2 (https=)
JP (1) JP2007505164A (https=)
WO (1) WO2004110978A2 (https=)

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JP2008536868A (ja) * 2005-04-15 2008-09-11 スミスクライン・ビーチャム・コーポレイション シアノアリールアミン
MX2009001442A (es) * 2006-08-09 2009-02-18 Smithkline Beecham Corp Pirrolidinona anilinas como moduladores del receptor de progesterona.
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
CA2716320C (en) * 2008-02-22 2014-01-28 Radius Health, Inc. Selective androgen receptor modulators
AU2009231892A1 (en) * 2008-03-31 2009-10-08 The Trustees Of Columbia University In The City Of New York Methods of diagnosing, preventing and treating bone mass diseases
AU2011212813B2 (en) 2010-02-04 2014-10-23 Radius Health, Inc. Selective androgen receptor modulators
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US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
DK2925725T3 (en) 2012-12-03 2017-01-16 Pfizer androgen receptor modulators
ES3055185T3 (en) 2014-03-28 2026-02-10 Univ Duke Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
SG11201608320QA (en) * 2014-05-15 2016-11-29 Pfizer Crystalline form of 6-[(4r)-4-methyl-1,2-dioxido-1,2,6-thiadiazinan-2-yl]isoquinoline-1-carbonitrile
ES2864079T3 (es) * 2014-05-30 2021-10-13 Pfizer Derivados de carbonitrilo como moduladores selectivos del receptor de andrógenos
US10017471B2 (en) 2015-04-21 2018-07-10 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10035763B2 (en) 2015-04-21 2018-07-31 Gtx, Inc. Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10865184B2 (en) 2015-04-21 2020-12-15 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10441570B2 (en) 2015-04-21 2019-10-15 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) Ligands and methods of use thereof
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US10093613B2 (en) 2015-04-21 2018-10-09 Gtx, Inc. Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10806720B2 (en) 2015-04-21 2020-10-20 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US9834507B2 (en) 2015-04-21 2017-12-05 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
CN107709290B (zh) 2015-04-21 2023-02-28 Gtx公司 选择性雄激素受体降解剂(sard)配体和其使用方法
RU2724103C2 (ru) 2015-04-21 2020-06-22 Джи Ти Икс, ИНК. Селективные лиганды-разрушители андрогенных рецептов (sard) и способы их применения
KR20250152679A (ko) 2015-04-29 2025-10-23 래디어스 파마슈티컬스, 인코포레이티드 암을 치료하는 방법
US11230523B2 (en) 2016-06-10 2022-01-25 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
MX389702B (es) 2016-06-22 2025-03-20 Ellipses Pharma Ltd Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+).
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ，インコーポレイテッド Ｒａｄ１９０１－２ｈｃｌの多形性形態
CA3099155A1 (en) 2018-05-14 2019-11-21 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
MX2020013713A (es) 2018-07-04 2021-03-02 Radius Pharmaceuticals Inc Formas polimorficas de rad1901-2hcl.
WO2020051344A1 (en) 2018-09-05 2020-03-12 University Of Tennessee Research Foundation Selective androgen receptor degrader (sard) ligands and methods of use thereof
EP3924328A1 (en) 2019-02-12 2021-12-22 Radius Pharmaceuticals, Inc. Processes and compounds
CA3138197A1 (en) 2019-05-14 2020-11-19 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
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MX2023011241A (es) 2021-03-23 2023-10-03 Nuvation Bio Inc Compuestos dirigidos a receptores de hormonas nucleares contra el cancer.
JP2024516024A (ja) 2021-05-03 2024-04-11 ニューベイション・バイオ・インコーポレイテッド 抗がん核内ホルモン受容体標的化化合物

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