JP2007526336A5 - - Google Patents
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- Publication number
- JP2007526336A5 JP2007526336A5 JP2007502061A JP2007502061A JP2007526336A5 JP 2007526336 A5 JP2007526336 A5 JP 2007526336A5 JP 2007502061 A JP2007502061 A JP 2007502061A JP 2007502061 A JP2007502061 A JP 2007502061A JP 2007526336 A5 JP2007526336 A5 JP 2007526336A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- trifluoromethyl
- cyano
- trifluoroethyl
- cyclopropylmethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54979404P | 2004-03-03 | 2004-03-03 | |
| US60/549,794 | 2004-03-03 | ||
| PCT/US2005/007245 WO2005085185A1 (en) | 2004-03-03 | 2005-03-03 | Aniline derivatives as selective androgen receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007526336A JP2007526336A (ja) | 2007-09-13 |
| JP2007526336A5 true JP2007526336A5 (https=) | 2008-04-17 |
| JP4805909B2 JP4805909B2 (ja) | 2011-11-02 |
Family
ID=34919539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502061A Expired - Lifetime JP4805909B2 (ja) | 2004-03-03 | 2005-03-03 | 選択的アンドロゲン受容体モジュレーターとしてのアニリン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7514470B2 (https=) |
| EP (1) | EP1725522B1 (https=) |
| JP (1) | JP4805909B2 (https=) |
| ES (1) | ES2523017T3 (https=) |
| WO (1) | WO2005085185A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007500245A (ja) * | 2003-06-10 | 2007-01-11 | スミスクライン ビーチャム コーポレーション | 化合物 |
| WO2004110978A2 (en) * | 2003-06-10 | 2004-12-23 | Smithkline Beecham Corporation | 1-aminonaphthalenes as modulators of androgen, glucocorticoid, mineralocorticoid and progesterone receptors |
| JP2008536868A (ja) * | 2005-04-15 | 2008-09-11 | スミスクライン・ビーチャム・コーポレイション | シアノアリールアミン |
| EP1954133A4 (en) * | 2005-11-30 | 2010-11-24 | Glaxosmithkline Llc | PYRROLIDINANILINE |
| JP5102985B2 (ja) * | 2006-07-18 | 2012-12-19 | 東ソ−・エフテック株式会社 | 含フッ素２級アミン化合物の製造方法 |
| MX2009001442A (es) | 2006-08-09 | 2009-02-18 | Smithkline Beecham Corp | Pirrolidinona anilinas como moduladores del receptor de progesterona. |
| JP5204438B2 (ja) * | 2007-07-31 | 2013-06-05 | 東ソ−・エフテック株式会社 | 含フッ素アミン化合物の製造方法 |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| CA2716320C (en) | 2008-02-22 | 2014-01-28 | Radius Health, Inc. | Selective androgen receptor modulators |
| AU2009231892A1 (en) * | 2008-03-31 | 2009-10-08 | The Trustees Of Columbia University In The City Of New York | Methods of diagnosing, preventing and treating bone mass diseases |
| JPWO2009136629A1 (ja) * | 2008-05-09 | 2011-09-08 | あすか製薬株式会社 | 生活習慣病予防・治療剤 |
| AT509045B1 (de) | 2010-01-29 | 2011-06-15 | Planta Naturstoffe Vertriebsges M B H | Verbindungen zur behandlung von asthma bronchiale |
| AU2011212813B2 (en) | 2010-02-04 | 2014-10-23 | Radius Health, Inc. | Selective androgen receptor modulators |
| HUE030072T2 (en) | 2010-05-12 | 2017-04-28 | Radius Health Inc | Therapeutic prescriptions |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| US9133182B2 (en) | 2010-09-28 | 2015-09-15 | Radius Health, Inc. | Selective androgen receptor modulators |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| ES3055185T3 (en) | 2014-03-28 | 2026-02-10 | Univ Duke | Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator |
| AU2015331756A1 (en) * | 2014-10-16 | 2017-05-04 | Gtx, Inc. | Methods of treating urological disorders using SARMs |
| MX389702B (es) | 2016-06-22 | 2025-03-20 | Ellipses Pharma Ltd | Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+). |
| JP7481115B2 (ja) | 2017-01-05 | 2024-05-10 | ラジウス ファーマシューティカルズ，インコーポレイテッド | Ｒａｄ１９０１－２ｈｃｌの多形性形態 |
| CA3099155A1 (en) | 2018-05-14 | 2019-11-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| MX2020013713A (es) | 2018-07-04 | 2021-03-02 | Radius Pharmaceuticals Inc | Formas polimorficas de rad1901-2hcl. |
| EP3924328A1 (en) | 2019-02-12 | 2021-12-22 | Radius Pharmaceuticals, Inc. | Processes and compounds |
| CA3138197A1 (en) | 2019-05-14 | 2020-11-19 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| EP4058464A1 (en) | 2019-11-13 | 2022-09-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| MX2023011241A (es) | 2021-03-23 | 2023-10-03 | Nuvation Bio Inc | Compuestos dirigidos a receptores de hormonas nucleares contra el cancer. |
| JP2024516024A (ja) | 2021-05-03 | 2024-04-11 | ニューベイション・バイオ・インコーポレイテッド | 抗がん核内ホルモン受容体標的化化合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2272433A1 (en) * | 1996-11-22 | 1998-05-28 | James E. Audia | N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions, and methods for inhibiting beta-amyloid peptide release and/or its synthesis |
| TR199901132T2 (xx) * | 1996-11-22 | 1999-08-23 | Elan Pharmaceuticals, Inc. | N-(aril/heteoaril) amino asit t�revleri, bunlar� i�eren farmas�tik bile�imler ve b�yle bile�ikler kullan�larak �-amiloid peptidinin sal�nmas�n� ve/veya sentezini inhibe etmek i�in y�ntemler. |
| US6506782B1 (en) * | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| AU2001263130A1 (en) * | 2000-06-06 | 2001-12-17 | Warner Lambert Company | Bicyclic cyclohexylamines and their use as nmda receptor antagonists |
| DE60137728D1 (de) * | 2000-08-24 | 2009-04-02 | Univ Tennessee Res Foundation | Selektive Modulatoren des Androgenrezeptors und Methoden zu deren Verwendung |
| CN1176905C (zh) * | 2002-03-22 | 2004-11-24 | 清华大学 | 甘氨酸乙酯邻苯二腈及其合成方法与应用 |
| JP2007500245A (ja) * | 2003-06-10 | 2007-01-11 | スミスクライン ビーチャム コーポレーション | 化合物 |
-
2005
- 2005-03-03 US US10/598,508 patent/US7514470B2/en not_active Expired - Lifetime
- 2005-03-03 EP EP05730067.5A patent/EP1725522B1/en not_active Expired - Lifetime
- 2005-03-03 WO PCT/US2005/007245 patent/WO2005085185A1/en not_active Ceased
- 2005-03-03 JP JP2007502061A patent/JP4805909B2/ja not_active Expired - Lifetime
- 2005-03-03 ES ES05730067.5T patent/ES2523017T3/es not_active Expired - Lifetime
-
2009
- 2009-02-25 US US12/392,687 patent/US7723385B2/en not_active Expired - Lifetime