JP2007500192A - 高度放射性プローブを組合わせたポリマーソーム - Google Patents

高度放射性プローブを組合わせたポリマーソーム Download PDF

Info

Publication number
JP2007500192A
JP2007500192A JP2006521968A JP2006521968A JP2007500192A JP 2007500192 A JP2007500192 A JP 2007500192A JP 2006521968 A JP2006521968 A JP 2006521968A JP 2006521968 A JP2006521968 A JP 2006521968A JP 2007500192 A JP2007500192 A JP 2007500192A
Authority
JP
Japan
Prior art keywords
polymersome
coumarin
poly
agent
radioactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006521968A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007500192A5 (https=
Inventor
ハマー、ダニエル、エー.
テリエン、マイケル、ジェイ.
ゴログチアン、パイマン、ピーター
Original Assignee
ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア filed Critical ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア
Publication of JP2007500192A publication Critical patent/JP2007500192A/ja
Publication of JP2007500192A5 publication Critical patent/JP2007500192A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036Porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • A61K49/0086Polymersome, i.e. liposome with polymerisable or polymerized bilayered-forming substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
JP2006521968A 2003-07-25 2004-07-26 高度放射性プローブを組合わせたポリマーソーム Pending JP2007500192A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49017803P 2003-07-25 2003-07-25
US10/777,552 US7682603B2 (en) 2003-07-25 2004-02-12 Polymersomes incorporating highly emissive probes
PCT/US2004/024014 WO2005016259A2 (en) 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes

Publications (2)

Publication Number Publication Date
JP2007500192A true JP2007500192A (ja) 2007-01-11
JP2007500192A5 JP2007500192A5 (https=) 2007-09-13

Family

ID=34083638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006521968A Pending JP2007500192A (ja) 2003-07-25 2004-07-26 高度放射性プローブを組合わせたポリマーソーム

Country Status (6)

Country Link
US (1) US7682603B2 (https=)
EP (1) EP1659938A4 (https=)
JP (1) JP2007500192A (https=)
AU (1) AU2004264877B2 (https=)
CA (1) CA2533637A1 (https=)
WO (1) WO2005016259A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010026781A1 (ja) * 2008-09-08 2010-03-11 国立大学法人東京農工大学 粒子およびその製造方法、ならびにゲル
JP2010539138A (ja) * 2007-09-14 2010-12-16 ミフェニオン ゲゼルシャフト ミット ベシュレンクテル ハフツング ナノ粒子製剤に基づく光学イメージング用診断物質
JP2011184367A (ja) * 2010-03-09 2011-09-22 Shiseido Co Ltd ポリマーソーム及び製造方法
JP2013503814A (ja) * 2008-09-09 2013-02-04 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ キレート化両親媒性ポリマー
JP2014503582A (ja) * 2011-01-28 2014-02-13 コーニンクレッカ フィリップス エヌ ヴェ 親水性プロドラッグの局所放出用担体
JP2016500071A (ja) * 2012-11-19 2016-01-07 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 免疫原に対する免疫応答を惹起するための方法

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20060127443A1 (en) * 2004-12-09 2006-06-15 Helmus Michael N Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery
US20070038176A1 (en) * 2005-07-05 2007-02-15 Jan Weber Medical devices with machined layers for controlled communications with underlying regions
WO2007027159A1 (en) * 2005-08-30 2007-03-08 Agency For Science, Technology And Research Water-soluble fluorescent particle comprising entangled fluorescent polymer and amphiphilic molecule
CA2624174A1 (en) * 2005-09-28 2007-04-05 The Trustees Of The University Of Pennsylvania Self-assembled biodegradable polymersomes
US8840660B2 (en) * 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US7842758B2 (en) * 2006-01-10 2010-11-30 The Trustees Of The University Of Pennsylvania Conjugated materials featuring proquinoidal units
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
WO2007106900A2 (en) * 2006-03-15 2007-09-20 The Trustees Of The University Of Pennsylvania Quantitative molecular probes
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) * 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) * 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US20070264303A1 (en) * 2006-05-12 2007-11-15 Liliana Atanasoska Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
EP2032091A2 (en) * 2006-06-29 2009-03-11 Boston Scientific Limited Medical devices with selective coating
US8052743B2 (en) 2006-08-02 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
GB2440910A (en) * 2006-08-18 2008-02-20 Robert Charles Wilson A marker for studying drug dynamics in vivo
JP2010503469A (ja) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
CA2663220A1 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
WO2008034066A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
WO2008034048A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprosthesis with biostable inorganic layers
US20080071353A1 (en) * 2006-09-15 2008-03-20 Boston Scientific Scimed, Inc. Endoprosthesis containing magnetic induction particles
US8808726B2 (en) * 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
JP2010503463A (ja) * 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 医療機器の生分解の制御
US8002821B2 (en) * 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
US20080069858A1 (en) * 2006-09-20 2008-03-20 Boston Scientific Scimed, Inc. Medical devices having biodegradable polymeric regions with overlying hard, thin layers
EP2084310A1 (en) * 2006-10-05 2009-08-05 Boston Scientific Limited Polymer-free coatings for medical devices formed by plasma electrolytic deposition
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
WO2008083190A2 (en) * 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) * 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US20080311045A1 (en) * 2007-06-06 2008-12-18 Biovaluation & Analysis, Inc. Polymersomes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
US7942926B2 (en) * 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) * 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
EP2187988B1 (en) 2007-07-19 2013-08-21 Boston Scientific Limited Endoprosthesis having a non-fouling surface
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8815273B2 (en) * 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
WO2009018340A2 (en) * 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
WO2009020520A1 (en) * 2007-08-03 2009-02-12 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
US20090047318A1 (en) * 2007-08-16 2009-02-19 Abbott Cardiovascular Systems Inc. Nanoparticle-coated medical devices and formulations for treating vascular disease
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090118809A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Endoprosthesis with porous reservoir and non-polymer diffusion layer
US8029554B2 (en) * 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) * 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US20090118812A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis coating
US20090118821A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis with porous reservoir and non-polymer diffusion layer
US20090143855A1 (en) * 2007-11-29 2009-06-04 Boston Scientific Scimed, Inc. Medical Device Including Drug-Loaded Fibers
US20100247445A1 (en) * 2007-12-07 2010-09-30 Koninklijke Philips Electronics N.V. Polymeric drug carrier for image-guided delivery
US20100008970A1 (en) * 2007-12-14 2010-01-14 Boston Scientific Scimed, Inc. Drug-Eluting Endoprosthesis
US20110002844A1 (en) * 2008-03-17 2011-01-06 The Trustees Of The University Of Pennsylvania Stabilization of macromolecular membranes
ES2423504T3 (es) 2008-04-22 2013-09-20 Boston Scientific Scimed, Inc. Dispositivos médicos que tienen un recubrimiento de material inorgánico
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) * 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8449603B2 (en) * 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating
US20100004733A1 (en) * 2008-07-02 2010-01-07 Boston Scientific Scimed, Inc. Implants Including Fractal Structures
US7985252B2 (en) * 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US20100057188A1 (en) * 2008-08-28 2010-03-04 Boston Scientific Scimed, Inc. Endoprostheses with porous regions and non-polymeric coating
US8114153B2 (en) * 2008-09-05 2012-02-14 Boston Scientific Scimed, Inc. Endoprostheses
US8951571B2 (en) * 2008-09-26 2015-02-10 The Trustees Of The University Of Pennsylvania Polymer vesicles for selective electromagnetic energy-induced delivery
US8382824B2 (en) * 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) * 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
WO2010101901A2 (en) * 2009-03-02 2010-09-10 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) * 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) * 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US20100274352A1 (en) * 2009-04-24 2010-10-28 Boston Scientific Scrimed, Inc. Endoprosthesis with Selective Drug Coatings
US20110022158A1 (en) * 2009-07-22 2011-01-27 Boston Scientific Scimed, Inc. Bioerodible Medical Implants
US20110022162A1 (en) * 2009-07-23 2011-01-27 Boston Scientific Scimed, Inc. Endoprostheses
JP5781518B2 (ja) * 2009-10-16 2015-09-24 ユニバーシティ・ヘルス・ネットワーク ポルフィリンナノ小胞
CN102791827B (zh) 2009-11-09 2016-11-16 华盛顿大学商业化中心 官能化发色聚合物点及其生物共轭体
US20130202712A1 (en) * 2010-03-02 2013-08-08 Vindico Nanobio Technology, Inc. Compositions And Methods For Treating Or Preventing Immuno-Inflammatory Disease
US8263752B2 (en) 2010-03-18 2012-09-11 Alltech, Inc. Methods for separating soluble selenoglycoproteins
US8575320B2 (en) 2010-03-18 2013-11-05 Alltech, Inc. Compositions and methods for separating, characterizing and administering soluble selenoglycoproteins
US8668732B2 (en) * 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US20110238153A1 (en) * 2010-03-26 2011-09-29 Boston Scientific Scimed, Inc. Endoprostheses
US8895099B2 (en) * 2010-03-26 2014-11-25 Boston Scientific Scimed, Inc. Endoprosthesis
JP5806289B2 (ja) 2010-04-06 2015-11-10 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 内部人工器官
KR20130062932A (ko) 2010-05-14 2013-06-13 말린크로트 엘엘씨 탠덤 광학 영상화 및 요법을 위한 관능성 가교결합된 나노구조
GB201008364D0 (en) * 2010-05-20 2010-07-07 Geneve De Composition and method
CA2814790C (en) 2010-10-18 2019-11-19 University of Washington Center for Commercialization Chromophoric polymer dots
US20140363496A1 (en) * 2011-01-07 2014-12-11 Vindico NanoBio Technology Inc. Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors
US9797840B2 (en) 2011-11-28 2017-10-24 University Of Washington Through Its Center For Commercialization Highly fluorescent polymer nanoparticle
CN104487097B (zh) 2011-12-30 2019-01-18 华盛顿大学商业中心 具有窄带发射的发色聚合物点
EP2809510B1 (en) 2012-02-03 2021-03-31 University of Washington through its Center for Commercialization Polyelectrolyte-coated polymer dots and related methods
SG11201501277RA (en) * 2012-08-29 2015-03-30 Agency Science Tech & Res Solid supported artificial cell membrane system
ES2764090T3 (es) * 2012-12-19 2020-06-02 Univ New York State Res Found Composiciones y procedimiento para la liberación activada por la luz de materiales de nanovesículas
WO2014153051A1 (en) 2013-03-14 2014-09-25 University Of Washington Through Its Center For Commercialization Polymer dot compositions and related methods
US9557337B2 (en) 2013-10-02 2017-01-31 Becton, Dickinson And Company Polymersome encapsulation of hydrophobic fluorescent polymers
US11077210B2 (en) * 2013-10-31 2021-08-03 Beth Israel Deaconess Medical Center Near-infrared fluorescent contrast bioimaging agents and methods of use thereof
US11001562B2 (en) * 2013-10-31 2021-05-11 Beth Israel Deaconess Medical Center Near-infrared fluorescent nerve contrast agents and methods of use thereof
US20160258848A1 (en) * 2015-03-04 2016-09-08 Agilent Technologies, Inc. Methods and compositions for multiplex tissue section analyses using visible and non-visible labels
US10456452B2 (en) 2015-07-02 2019-10-29 Poseida Therapeutics, Inc. Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
JP6927995B2 (ja) 2016-03-11 2021-09-01 イリノイ トゥール ワークス インコーポレイティド 燐光性強磁性粒子配合物及び該配合物を用いた非破壊試験の方法
ES2865481T3 (es) 2016-04-29 2021-10-15 Poseida Therapeutics Inc Micelas basadas en poli(histidina) para la complejación y el aporte de proteínas y ácidos nucleicos
AU2017283653C1 (en) 2016-06-16 2022-05-05 Oncoselect Therapeutics, Llc Porphyrin compounds and compositions useful for treating cancer
DK3500311T3 (da) 2016-08-16 2020-08-17 Eth Zuerich Trans-membran ph-gradient polymersomer og deres anvendelse i rensningen af ammoniak og dens denaturerede analoge
FI3668927T3 (fi) * 2017-09-12 2024-04-05 Eth Zuerich Transmembraaniset ph-gradienttipolymeerit ammoniakin kvantifiointiin kehon nesteissä
CN108743980B (zh) * 2018-07-06 2021-05-18 重庆医科大学 一种叶酸靶向可视化光热-化疗治疗剂及其制备方法
US20210154335A1 (en) * 2019-11-27 2021-05-27 Board Of Regents, The University Of Texas System Dye aggregates-containing nanoparticles and uses thereof
TWI752555B (zh) * 2020-07-16 2022-01-11 義守大學 可提高葉綠素穩定性的包覆微粒及其製造方法
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
US12440585B2 (en) 2023-09-12 2025-10-14 Curadel Surgical Innovations, Inc. Zwitterionic metal chelators
CN118459750B (zh) * 2024-07-15 2024-09-20 吉林大学 一种基于共价组装体的人工光捕获系统及其构建方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0454132A (ja) * 1990-06-20 1992-02-21 Hitachi Ltd 波動による腫瘍治療用生理作用増強剤及びその製法
JPH11509834A (ja) * 1995-08-02 1999-08-31 キューエルティー フォトセラピューティクス,インコーポレイテッド ヒドロ−モノベンゾポルフィリン光増感剤を含有するリポソームの作成方法
JP2001508071A (ja) * 1997-01-10 2001-06-19 アルタレックス コーポレイション 光力学的治療で使用する置換ペリレンキノン
WO2002104072A2 (en) * 2001-02-26 2002-12-27 The Trustees Of The University Of Pennsylvania Emissive multichromophoric systems
JP2003518015A (ja) * 1999-11-05 2003-06-03 バイオキュア・インコーポレーテッド 両親媒性ポリマーベシクル

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975512A (en) * 1970-12-21 1976-08-17 University Of Illinois Foundation Non-toxic brominated perfluorocarbons radiopaque agents
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US4972331A (en) * 1989-02-06 1990-11-20 Nim, Inc. Phase modulated spectrophotometry
US5187672A (en) * 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
US6100392A (en) * 1992-08-14 2000-08-08 The Trustees Of The University Of Pennsylavania Electron-deficient porphyrins and processes and intermediates for preparing same
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5783306A (en) * 1992-08-14 1998-07-21 Trustees Of The University Of Pennsylvania Hyperpolarizable compounds and devices fabricated therefrom
US5571864A (en) * 1993-03-23 1996-11-05 Regents Of The University Of Minnesota Miscible polyolefin blends with modifying polyolefin having matching segment lengths
US5493018A (en) * 1994-01-25 1996-02-20 Merck & Co., Inc. Process for synthesizing carbapenem intermediates using a rhodium catalyst and lewis acid
US6159445A (en) * 1994-07-20 2000-12-12 Nycomed Imaging As Light imaging contrast agents
US5707608A (en) * 1995-08-02 1998-01-13 Qlt Phototherapeutics, Inc. Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
US6060518A (en) * 1996-08-16 2000-05-09 Supratek Pharma Inc. Polymer compositions for chemotherapy and methods of treatment using the same
US6123923A (en) * 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US7182933B2 (en) * 2000-10-12 2007-02-27 The University Of Tennessee Research Corporation Targeting drug/gene carriers to irradiated tissue
KR100448170B1 (ko) * 2001-06-23 2004-09-10 주식회사 태평양 폴리에틸렌이민을 친수성 블록으로 갖고 폴리에스테르계고분자를 소수성 블록으로 갖는 양친성 생분해성 블록공중합체 및 이를 이용한 수용액 상에서의 고분자자기조합 회합체

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0454132A (ja) * 1990-06-20 1992-02-21 Hitachi Ltd 波動による腫瘍治療用生理作用増強剤及びその製法
JPH11509834A (ja) * 1995-08-02 1999-08-31 キューエルティー フォトセラピューティクス,インコーポレイテッド ヒドロ−モノベンゾポルフィリン光増感剤を含有するリポソームの作成方法
JP2001508071A (ja) * 1997-01-10 2001-06-19 アルタレックス コーポレイション 光力学的治療で使用する置換ペリレンキノン
JP2003518015A (ja) * 1999-11-05 2003-06-03 バイオキュア・インコーポレーテッド 両親媒性ポリマーベシクル
WO2002104072A2 (en) * 2001-02-26 2002-12-27 The Trustees Of The University Of Pennsylvania Emissive multichromophoric systems
JP2005503453A (ja) * 2001-02-26 2005-02-03 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 発光性多色発色団系

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6010069624; PHOTOS,P.J. et al: 'Polymer vesicles in vivo: correlations with PEG molecular weight' J Control Release Vol.90, No.3, 2003, p.323-34 *
JPN6010069625; DISCHER,B.M. et al: 'Polymersomes: tough vesicles made from diblock copolymers' Science Vol.284, No.5417, 1999, p.1143-6 *
JPN6010069626; LEE,J.C. et al: 'Preparation, stability, and in vitro performance of vesicles made with diblock copolymers' Biotechnol Bioeng Vol.73, No.2, 2001, p.135-45 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010539138A (ja) * 2007-09-14 2010-12-16 ミフェニオン ゲゼルシャフト ミット ベシュレンクテル ハフツング ナノ粒子製剤に基づく光学イメージング用診断物質
US9821077B2 (en) 2007-09-14 2017-11-21 Nanopet Pharma Gmbh Diagnostic substances for optical imaging testing on the basis of nanoparticular formulations
WO2010026781A1 (ja) * 2008-09-08 2010-03-11 国立大学法人東京農工大学 粒子およびその製造方法、ならびにゲル
JP2010064956A (ja) * 2008-09-08 2010-03-25 Tokyo Univ Of Agriculture & Technology 粒子およびその製造方法、ならびにゲル
JP2013503814A (ja) * 2008-09-09 2013-02-04 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ キレート化両親媒性ポリマー
JP2011184367A (ja) * 2010-03-09 2011-09-22 Shiseido Co Ltd ポリマーソーム及び製造方法
JP2014503582A (ja) * 2011-01-28 2014-02-13 コーニンクレッカ フィリップス エヌ ヴェ 親水性プロドラッグの局所放出用担体
JP2016500071A (ja) * 2012-11-19 2016-01-07 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 免疫原に対する免疫応答を惹起するための方法
JP2019011358A (ja) * 2012-11-19 2019-01-24 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 医薬組成物

Also Published As

Publication number Publication date
EP1659938A2 (en) 2006-05-31
AU2004264877B2 (en) 2010-12-02
AU2004264877A1 (en) 2005-02-24
CA2533637A1 (en) 2005-02-24
WO2005016259A3 (en) 2005-12-29
US20050019265A1 (en) 2005-01-27
US7682603B2 (en) 2010-03-23
WO2005016259A2 (en) 2005-02-24
EP1659938A4 (en) 2010-03-24

Similar Documents

Publication Publication Date Title
JP2007500192A (ja) 高度放射性プローブを組合わせたポリマーソーム
Jalani et al. Seeing, targeting and delivering with upconverting nanoparticles
Reisch et al. Fluorescent polymer nanoparticles based on dyes: seeking brighter tools for bioimaging
Pfister et al. Boron polylactide nanoparticles exhibiting fluorescence and phosphorescence in aqueous medium
Quan et al. Near-infrared emitting fluorescent BODIPY nanovesicles for in vivo molecular imaging and drug delivery
JP2007500192A5 (https=)
US8709383B2 (en) Persistent luminescence nanoparticles used in the form of a diagnosis agent for in vivo optical imaging
Cong et al. Tuning the brightness and photostability of organic dots for multivalent targeted cancer imaging and surgery
Fleige et al. Aggregation phenomena of host and guest upon the loading of dendritic core-multishell nanoparticles with solvatochromic dyes
Yan et al. General and scalable approach to bright, stable, and functional AIE fluorogen colloidal nanocrystals for in vivo imaging
CA2924018C (en) Cell-specific targeting using nanostructured delivery systems
Takeda et al. In vivo single molecular imaging and sentinel node navigation by nanotechnology for molecular targeting drug-delivery systems and tailor-made medicine
Kritchenkov et al. Functionalized Pt (II) and Ir (III) NIR emitters and their covalent conjugates with polymer-based nanocarriers
Morla-Folch et al. Dye-Loaded quatsomes exhibiting FRET as nanoprobes for bioimaging
Yu et al. Dual-responsive micelles with aggregation-induced emission feature and two-photon aborsption for accurate drug delivery and bioimaging
KR20190001022A (ko) 광감작제를 포함한 마이크로버블-나노입자 복합체 및 이를 포함하는 항암 치료제
Lu et al. Irradiation induced fluorescence enhancement in PEGylated cyanine-based NIR nano-and mesoscale GUMBOS
Cheng et al. Water-soluble single-chain polymeric nanoparticles for highly selective cancer chemotherapy
WO2012118136A1 (ja) スイッチング型蛍光ナノ粒子プローブ及びそれを用いた蛍光分子イメージング法
Jana et al. Morphology tuning of self-assembled perylene monoimide from nanoparticles to colloidosomes with enhanced excimeric NIR emission for bioimaging
Chen et al. Targeted cyclo [8] pyrrole-Based NIR-II photoacoustic tomography probe for suppression of orthotopic pancreatic tumor growth and intra-abdominal metastases
Wang et al. Lipid coated upconverting nanoparticles as NIR remote controlled transducer for simultaneous photodynamic therapy and cell imaging
US8951571B2 (en) Polymer vesicles for selective electromagnetic energy-induced delivery
Papadimitriou et al. Smart polymeric nanoparticles as emerging tools for imaging—the parallel evolution of materials
Palange et al. Boosting the Potential of Chemotherapy in Advanced Breast Cancer Lung Metastasis via Micro‐Combinatorial Hydrogel Particles

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070726

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070726

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101207

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110304

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110311

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110607

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120221

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120519

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120528

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120821

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130319

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130903