CA2533637A1 - Polymersomes incorporating highly emissive probes - Google Patents

Polymersomes incorporating highly emissive probes Download PDF

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Publication number
CA2533637A1
CA2533637A1 CA002533637A CA2533637A CA2533637A1 CA 2533637 A1 CA2533637 A1 CA 2533637A1 CA 002533637 A CA002533637 A CA 002533637A CA 2533637 A CA2533637 A CA 2533637A CA 2533637 A1 CA2533637 A1 CA 2533637A1
Authority
CA
Canada
Prior art keywords
polymersome
agent
coumarin
emissive
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002533637A
Other languages
English (en)
French (fr)
Inventor
Daniel A. Hammer
Michael J. Therien
Paiman Peter Ghoroghchian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2533637A1 publication Critical patent/CA2533637A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • A61K49/0086—Polymersome, i.e. liposome with polymerisable or polymerized bilayered-forming substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CA002533637A 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes Abandoned CA2533637A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49017803P 2003-07-25 2003-07-25
US60/490,178 2003-07-25
US10/777,552 2004-02-12
US10/777,552 US7682603B2 (en) 2003-07-25 2004-02-12 Polymersomes incorporating highly emissive probes
PCT/US2004/024014 WO2005016259A2 (en) 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes

Publications (1)

Publication Number Publication Date
CA2533637A1 true CA2533637A1 (en) 2005-02-24

Family

ID=34083638

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002533637A Abandoned CA2533637A1 (en) 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes

Country Status (6)

Country Link
US (1) US7682603B2 (https=)
EP (1) EP1659938A4 (https=)
JP (1) JP2007500192A (https=)
AU (1) AU2004264877B2 (https=)
CA (1) CA2533637A1 (https=)
WO (1) WO2005016259A2 (https=)

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Also Published As

Publication number Publication date
EP1659938A2 (en) 2006-05-31
AU2004264877B2 (en) 2010-12-02
AU2004264877A1 (en) 2005-02-24
WO2005016259A3 (en) 2005-12-29
US20050019265A1 (en) 2005-01-27
US7682603B2 (en) 2010-03-23
JP2007500192A (ja) 2007-01-11
WO2005016259A2 (en) 2005-02-24
EP1659938A4 (en) 2010-03-24

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