AU2004264877B2 - Polymersomes incorporating highly emissive probes - Google Patents

Polymersomes incorporating highly emissive probes Download PDF

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Publication number
AU2004264877B2
AU2004264877B2 AU2004264877A AU2004264877A AU2004264877B2 AU 2004264877 B2 AU2004264877 B2 AU 2004264877B2 AU 2004264877 A AU2004264877 A AU 2004264877A AU 2004264877 A AU2004264877 A AU 2004264877A AU 2004264877 B2 AU2004264877 B2 AU 2004264877B2
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Australia
Prior art keywords
polymersome
emissive
moieties
compound
polymer
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Expired
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AU2004264877A
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AU2004264877A1 (en
Inventor
Paiman Peter Ghoroghchian
Daniel A. Hammer
Michael J. Therien
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • A61K49/0086—Polymersome, i.e. liposome with polymerisable or polymerized bilayered-forming substances

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AU2004264877A 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes Expired AU2004264877B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49017803P 2003-07-25 2003-07-25
US60/490,178 2003-07-25
US10/777,552 US7682603B2 (en) 2003-07-25 2004-02-12 Polymersomes incorporating highly emissive probes
US10/777,552 2004-02-12
PCT/US2004/024014 WO2005016259A2 (en) 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes

Publications (2)

Publication Number Publication Date
AU2004264877A1 AU2004264877A1 (en) 2005-02-24
AU2004264877B2 true AU2004264877B2 (en) 2010-12-02

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Family Applications (1)

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AU2004264877A Expired AU2004264877B2 (en) 2003-07-25 2004-07-26 Polymersomes incorporating highly emissive probes

Country Status (6)

Country Link
US (1) US7682603B2 (https=)
EP (1) EP1659938A4 (https=)
JP (1) JP2007500192A (https=)
AU (1) AU2004264877B2 (https=)
CA (1) CA2533637A1 (https=)
WO (1) WO2005016259A2 (https=)

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EP1659938A2 (en) 2006-05-31
WO2005016259A3 (en) 2005-12-29
US20050019265A1 (en) 2005-01-27
JP2007500192A (ja) 2007-01-11
CA2533637A1 (en) 2005-02-24
EP1659938A4 (en) 2010-03-24
WO2005016259A2 (en) 2005-02-24
AU2004264877A1 (en) 2005-02-24
US7682603B2 (en) 2010-03-23

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