JP2006527729A - 急性血管疾患の治療用のｘａ因子阻害剤としての１−フェニル−２−オキソ−３−スルホニルアミノ−ピロリジン誘導体および関連化合物 - Google Patents
急性血管疾患の治療用のｘａ因子阻害剤としての１−フェニル−２−オキソ−３−スルホニルアミノ−ピロリジン誘導体および関連化合物 Download PDFInfo
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- JP2006527729A JP2006527729A JP2006515988A JP2006515988A JP2006527729A JP 2006527729 A JP2006527729 A JP 2006527729A JP 2006515988 A JP2006515988 A JP 2006515988A JP 2006515988 A JP2006515988 A JP 2006515988A JP 2006527729 A JP2006527729 A JP 2006527729A
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- alkyl
- amino
- oxo
- pyrrolidinyl
- thienyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0314299.9A GB0314299D0 (en) | 2003-06-19 | 2003-06-19 | Chemical compounds |
| PCT/EP2004/006592 WO2004110435A1 (en) | 2003-06-19 | 2004-06-17 | 1-phenyl-2-oxo-3-sulfonylamino-pyrrolidine derivatives and related compounds as factor xa inhibitors for the treatment of acute vascular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006527729A true JP2006527729A (ja) | 2006-12-07 |
| JP2006527729A5 JP2006527729A5 (enExample) | 2007-08-09 |
Family
ID=27636926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515988A Withdrawn JP2006527729A (ja) | 2003-06-19 | 2004-06-17 | 急性血管疾患の治療用のｘａ因子阻害剤としての１−フェニル−２−オキソ−３−スルホニルアミノ−ピロリジン誘導体および関連化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7329685B2 (enExample) |
| EP (1) | EP1635817B1 (enExample) |
| JP (1) | JP2006527729A (enExample) |
| AT (1) | ATE345795T1 (enExample) |
| DE (1) | DE602004003380T2 (enExample) |
| ES (1) | ES2276307T3 (enExample) |
| GB (1) | GB0314299D0 (enExample) |
| WO (1) | WO2004110435A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| PE20071085A1 (es) * | 2005-11-24 | 2007-12-16 | Glaxo Group Ltd | COMPUESTOS 2-OXO-3-PIRRODINIL COMO INHIBIDORES DEL FACTOR Xa |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202344A (en) | 1990-12-11 | 1993-04-13 | G. D. Searle & Co. | N-substituted lactams useful as cholecystokinin antagonists |
| US6034093A (en) | 1995-06-07 | 2000-03-07 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| US5827875A (en) | 1996-05-10 | 1998-10-27 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
| EP1294684A2 (en) | 2000-06-29 | 2003-03-26 | Bristol-Myers Squibb Pharma Company | THROMBIN OR FACTOR Xa INHIBITORS |
| US6710058B2 (en) | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
| US6348600B1 (en) | 2001-02-20 | 2002-02-19 | Toray Industries, Inc. | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative |
| AU2002303264A1 (en) | 2001-04-09 | 2002-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic inhibitors of factor xa |
| GB0127568D0 (en) | 2001-11-16 | 2002-01-09 | Glaxo Group Ltd | Chemical compounds |
| GB0130705D0 (en) | 2001-12-21 | 2002-02-06 | Glaxo Group Ltd | Chemical compounds |
| TW200307667A (en) * | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
-
2003
- 2003-06-19 GB GBGB0314299.9A patent/GB0314299D0/en not_active Ceased
-
2004
- 2004-06-17 JP JP2006515988A patent/JP2006527729A/ja not_active Withdrawn
- 2004-06-17 WO PCT/EP2004/006592 patent/WO2004110435A1/en not_active Ceased
- 2004-06-17 ES ES04736979T patent/ES2276307T3/es not_active Expired - Lifetime
- 2004-06-17 DE DE602004003380T patent/DE602004003380T2/de not_active Expired - Fee Related
- 2004-06-17 US US10/561,545 patent/US7329685B2/en not_active Expired - Fee Related
- 2004-06-17 AT AT04736979T patent/ATE345795T1/de not_active IP Right Cessation
- 2004-06-17 EP EP04736979A patent/EP1635817B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB0314299D0 (en) | 2003-07-23 |
| DE602004003380T2 (de) | 2007-10-04 |
| DE602004003380D1 (de) | 2007-01-04 |
| US20060148879A1 (en) | 2006-07-06 |
| ES2276307T3 (es) | 2007-06-16 |
| EP1635817B1 (en) | 2006-11-22 |
| WO2004110435A1 (en) | 2004-12-23 |
| ATE345795T1 (de) | 2006-12-15 |
| EP1635817A1 (en) | 2006-03-22 |
| US7329685B2 (en) | 2008-02-12 |
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