ES2276307T3 - Derivados de 1-fenil-2-oxo-3-sulfonilamino-pirrolidina y compuestos relacionados como inhibidores del factor xa para el tratamiento de enfermedades vasculares agudas. - Google Patents
Derivados de 1-fenil-2-oxo-3-sulfonilamino-pirrolidina y compuestos relacionados como inhibidores del factor xa para el tratamiento de enfermedades vasculares agudas. Download PDFInfo
- Publication number
- ES2276307T3 ES2276307T3 ES04736979T ES04736979T ES2276307T3 ES 2276307 T3 ES2276307 T3 ES 2276307T3 ES 04736979 T ES04736979 T ES 04736979T ES 04736979 T ES04736979 T ES 04736979T ES 2276307 T3 ES2276307 T3 ES 2276307T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- amino
- oxo
- pyrrolidinyl
- thienyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- A—HUMAN NECESSITIES
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- A61P25/16—Anti-Parkinson drugs
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Medicinal Chemistry (AREA)
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- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0314299 | 2003-06-19 | ||
| GBGB0314299.9A GB0314299D0 (en) | 2003-06-19 | 2003-06-19 | Chemical compounds |
Publications (1)
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|---|---|
| ES2276307T3 true ES2276307T3 (es) | 2007-06-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES04736979T Expired - Lifetime ES2276307T3 (es) | 2003-06-19 | 2004-06-17 | Derivados de 1-fenil-2-oxo-3-sulfonilamino-pirrolidina y compuestos relacionados como inhibidores del factor xa para el tratamiento de enfermedades vasculares agudas. |
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| Country | Link |
|---|---|
| US (1) | US7329685B2 (enExample) |
| EP (1) | EP1635817B1 (enExample) |
| JP (1) | JP2006527729A (enExample) |
| AT (1) | ATE345795T1 (enExample) |
| DE (1) | DE602004003380T2 (enExample) |
| ES (1) | ES2276307T3 (enExample) |
| GB (1) | GB0314299D0 (enExample) |
| WO (1) | WO2004110435A1 (enExample) |
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| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| PE20071085A1 (es) * | 2005-11-24 | 2007-12-16 | Glaxo Group Ltd | COMPUESTOS 2-OXO-3-PIRRODINIL COMO INHIBIDORES DEL FACTOR Xa |
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| US5202344A (en) | 1990-12-11 | 1993-04-13 | G. D. Searle & Co. | N-substituted lactams useful as cholecystokinin antagonists |
| US6034093A (en) | 1995-06-07 | 2000-03-07 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| US5827875A (en) | 1996-05-10 | 1998-10-27 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
| EP1294684A2 (en) | 2000-06-29 | 2003-03-26 | Bristol-Myers Squibb Pharma Company | THROMBIN OR FACTOR Xa INHIBITORS |
| US6710058B2 (en) | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
| US6348600B1 (en) | 2001-02-20 | 2002-02-19 | Toray Industries, Inc. | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative |
| AU2002303264A1 (en) | 2001-04-09 | 2002-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic inhibitors of factor xa |
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| GB0130705D0 (en) | 2001-12-21 | 2002-02-06 | Glaxo Group Ltd | Chemical compounds |
| TW200307667A (en) * | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
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2003
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2004
- 2004-06-17 JP JP2006515988A patent/JP2006527729A/ja not_active Withdrawn
- 2004-06-17 WO PCT/EP2004/006592 patent/WO2004110435A1/en not_active Ceased
- 2004-06-17 ES ES04736979T patent/ES2276307T3/es not_active Expired - Lifetime
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Also Published As
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|---|---|
| GB0314299D0 (en) | 2003-07-23 |
| DE602004003380T2 (de) | 2007-10-04 |
| DE602004003380D1 (de) | 2007-01-04 |
| JP2006527729A (ja) | 2006-12-07 |
| US20060148879A1 (en) | 2006-07-06 |
| EP1635817B1 (en) | 2006-11-22 |
| WO2004110435A1 (en) | 2004-12-23 |
| ATE345795T1 (de) | 2006-12-15 |
| EP1635817A1 (en) | 2006-03-22 |
| US7329685B2 (en) | 2008-02-12 |
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