JP2006527264A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006527264A5 JP2006527264A5 JP2006516839A JP2006516839A JP2006527264A5 JP 2006527264 A5 JP2006527264 A5 JP 2006527264A5 JP 2006516839 A JP2006516839 A JP 2006516839A JP 2006516839 A JP2006516839 A JP 2006516839A JP 2006527264 A5 JP2006527264 A5 JP 2006527264A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- hydrogen atom
- formula
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CN(C)*[n]1ncc-2c1N(C)C(N)[n]1nc(*)nc-21 Chemical compound CN(C)*[n]1ncc-2c1N(C)C(N)[n]1nc(*)nc-21 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50904603P | 2003-06-10 | 2003-06-10 | |
| US60/509,046 | 2003-06-10 | ||
| US53279303P | 2003-12-24 | 2003-12-24 | |
| US60/532,793 | 2003-12-24 | ||
| PCT/JP2004/008486 WO2004108137A1 (en) | 2003-06-10 | 2004-06-10 | A method of treating an anxiety disorder |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006527264A JP2006527264A (ja) | 2006-11-30 |
| JP2006527264A5 true JP2006527264A5 (enExample) | 2007-06-07 |
| JP4778894B2 JP4778894B2 (ja) | 2011-09-21 |
Family
ID=33514319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006516839A Expired - Fee Related JP4778894B2 (ja) | 2003-06-10 | 2004-06-10 | 不安障害の治療方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8202869B2 (enExample) |
| EP (1) | EP1631294B1 (enExample) |
| JP (1) | JP4778894B2 (enExample) |
| KR (1) | KR20060037252A (enExample) |
| CN (1) | CN1787821A (enExample) |
| AT (1) | ATE481101T1 (enExample) |
| AU (1) | AU2004244906A1 (enExample) |
| BR (1) | BRPI0411120A (enExample) |
| CA (1) | CA2528710C (enExample) |
| CO (1) | CO5640121A2 (enExample) |
| DE (1) | DE602004029160D1 (enExample) |
| EA (1) | EA200501924A1 (enExample) |
| MX (1) | MXPA05013148A (enExample) |
| NO (1) | NO20055907L (enExample) |
| WO (1) | WO2004108137A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150080013A (ko) * | 2002-01-28 | 2015-07-08 | 교와 핫꼬 기린 가부시키가이샤 | 운동성 질환에 걸린 환자의 치료용 조성물 |
| US10042980B2 (en) | 2005-11-17 | 2018-08-07 | Gearbox Llc | Providing assistance related to health |
| US20070124176A1 (en) * | 2005-11-30 | 2007-05-31 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
| US20070136092A1 (en) * | 2005-11-30 | 2007-06-14 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging |
| US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
| US7994190B2 (en) | 2006-11-01 | 2011-08-09 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
| US20090082341A1 (en) * | 2007-07-23 | 2009-03-26 | Synosia Therapeutics | 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide FOR THE TREATMENT OF POST-TRAUMATIC STRESS DISORDER |
| UA113383C2 (xx) | 2009-09-02 | 2017-01-25 | Терапевтичний агент для лікування тривожних розладів | |
| UA110097C2 (uk) | 2009-09-02 | 2015-11-25 | Терапевтичний агент для лікування розладів настрою | |
| US8609162B2 (en) | 2012-10-04 | 2013-12-17 | Invivo Beverages Llc | Integrated neuromodulation system for mood enhancement of a living human subject |
| CN105770563A (zh) * | 2016-04-22 | 2016-07-20 | 孙建 | 一种治疗焦虑症的中药制剂及其制备方法 |
| WO2019168847A1 (en) | 2018-02-27 | 2019-09-06 | Incyte Corporation | Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors |
| US11168089B2 (en) | 2018-05-18 | 2021-11-09 | Incyte Corporation | Fused pyrimidine derivatives as A2A / A2B inhibitors |
| JOP20200342A1 (ar) | 2018-07-05 | 2020-12-30 | Incyte Corp | مشتقات بيرازين مدمجة كمثبطات a2a/a2b |
| TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
| WO2022167778A1 (en) | 2021-02-02 | 2022-08-11 | Haiku Therapeutics Ltd | Ebselen as adenosine receptor modulator |
| KR102594242B1 (ko) | 2023-01-10 | 2023-10-27 | 주식회사 웨이센 | 디지털 표현형 특징을 이용한 사회 불안장애 분석방법 및 장치 |
| KR102567684B1 (ko) | 2023-01-10 | 2023-08-18 | 주식회사 웨이센 | 디지털 표현형 특징을 이용한 사회 불안장애 분석방법 및 장치 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2051772T3 (es) * | 1986-09-30 | 1994-07-01 | Ciba Geigy Ag | 2-sustituido-e-fusionado-(1,2,4)-triazol(1,5-c)pirimidinas, composiciones farmaceuticas y sus usos. |
| US5047534A (en) * | 1990-03-26 | 1991-09-10 | Merrell Dow Pharmaceuticals Inc. | Selective adenosine receptor agents |
| US5484920A (en) | 1992-04-08 | 1996-01-16 | Kyowa Hakko Kogyo Co., Ltd. | Therapeutic agent for Parkinson's disease |
| PT628311E (pt) | 1992-07-08 | 2002-09-30 | Kyowa Hakko Kogyo Kk | Derivado de xantina com actividade antidepressiva |
| ES2264210T3 (es) | 1997-09-05 | 2006-12-16 | Kyowa Hakko Kogyo Co., Ltd. | Derivados de xantina para el tratamiento de la isquemia cerebral. |
| BR9914040A (pt) | 1998-09-22 | 2002-01-15 | Kyowa Hakko Kogyo Kk | Derivados de [1,2,4]triazolo[1,5-c]pirimidina e seu uso, medicamento, antagonista, agente para prevenir ou tratar doenças, bem como processo para prevenção ou tratamento de distúrbios |
| WO2000069464A1 (en) * | 1999-05-12 | 2000-11-23 | Fujisawa Pharmaceutical Co., Ltd. | Novel use |
| JP4574112B2 (ja) * | 2000-05-26 | 2010-11-04 | シェーリング コーポレイション | アデノシンａ２ａレセプターアンタゴニスト |
| CA2459304A1 (en) * | 2001-09-13 | 2003-03-20 | Schering Corporation | Combination of an adenosine a2a receptor antagonist and an antidepressant or anxiolytic |
| JP4545437B2 (ja) * | 2001-10-15 | 2010-09-15 | シェーリング コーポレイション | アデノシンａ２ａ受容体アンタゴニストとしてのイミダゾ（４，３−ｅ）−１，２，４−トリアゾロ（１，５−ｃ）ピリミジン |
| WO2003043637A1 (en) * | 2001-11-20 | 2003-05-30 | Bristol-Myers Squibb Pharma Company | 3,7-dihydro-purine-2,6-dione derivatives as crf receptor ligands |
| US20060128694A1 (en) * | 2002-12-19 | 2006-06-15 | Michael Grzelak | Adenosine A2a receptor antagonists for the treatment of extra-pyramidal syndrome and other movement disorders |
-
2004
- 2004-06-10 KR KR1020057021878A patent/KR20060037252A/ko not_active Withdrawn
- 2004-06-10 AU AU2004244906A patent/AU2004244906A1/en not_active Abandoned
- 2004-06-10 CN CNA2004800128457A patent/CN1787821A/zh active Pending
- 2004-06-10 DE DE602004029160T patent/DE602004029160D1/de not_active Expired - Lifetime
- 2004-06-10 EA EA200501924A patent/EA200501924A1/ru unknown
- 2004-06-10 CA CA2528710A patent/CA2528710C/en not_active Expired - Fee Related
- 2004-06-10 BR BRPI0411120-6A patent/BRPI0411120A/pt not_active IP Right Cessation
- 2004-06-10 US US10/553,250 patent/US8202869B2/en not_active Expired - Fee Related
- 2004-06-10 AT AT04746014T patent/ATE481101T1/de not_active IP Right Cessation
- 2004-06-10 MX MXPA05013148A patent/MXPA05013148A/es unknown
- 2004-06-10 EP EP04746014A patent/EP1631294B1/en not_active Expired - Lifetime
- 2004-06-10 JP JP2006516839A patent/JP4778894B2/ja not_active Expired - Fee Related
- 2004-06-10 WO PCT/JP2004/008486 patent/WO2004108137A1/en not_active Ceased
-
2005
- 2005-12-13 NO NO20055907A patent/NO20055907L/no not_active Application Discontinuation
-
2006
- 2006-01-10 CO CO06001545A patent/CO5640121A2/es not_active Application Discontinuation
-
2012
- 2012-04-16 US US13/447,798 patent/US8592420B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006527264A5 (enExample) | ||
| JP6360025B2 (ja) | 有機化合物 | |
| AU715380B2 (en) | Pyrazolopyrimidines for treatment of neuronal and other disorders | |
| JP6038250B2 (ja) | 有機化合物 | |
| JP5656874B2 (ja) | Ｐｄｅ９阻害剤として使用されるアミノヘテロ環化合物 | |
| CA2608301C (en) | Pyrido[2,3-d]pyrimidines useful as hcv inhibitors, and methods for the preparation thereof | |
| Xu et al. | Developments of indoles as anti-HIV-1 inhibitors | |
| JP2002533464A (ja) | プテリジン誘導体の免疫抑制作用 | |
| RU2007126570A (ru) | Аминоимидазолоны, применяемые для ингибирования бета-секретазы | |
| ITMI951671A1 (it) | Analoghi eterociclici di 1,2,4-triazolo[1,5-c]pirimidine ad attivita' antagonista per il recettore a2a dell'adenosina | |
| AU2008276455A1 (en) | Combinations for the treatment of B-cell proliferative disorders | |
| NO20055510L (no) | 2-alkynyl- og 2-alkenylpyrazolo [4,3-E]-1,2,4-triazolo-[1,5-C]-pyrimidin-adenosin A2A-reseptorantagonister | |
| AU2008276451A1 (en) | Treatments of B-cell proliferative disorders | |
| AR037680A1 (es) | Antagonistas del receptor de adenosina a2a de 5-amino-pirazolo-[4,3-e]-1,2,4-triazolo[1,5-c]-pirimidinas sustituidas, composiciones farmaceuticas que los comprenden, el uso de dichos compuestos, solos o en combinacion para la elaboracion de un medicamento utiles para el tratamiento de enfermedades d | |
| JP2013523889A5 (enExample) | ||
| JP2009533343A5 (enExample) | ||
| Janetka et al. | Inhibitors of checkpoint kinases: from discovery to the clinic | |
| JPH083041A (ja) | ストレス関連障害治療剤 | |
| RU2003124653A (ru) | Производные пурина в качестве антагонистов пуринергических рецепторов | |
| EA200800992A1 (ru) | 2-амино-7,8-дигидро-6н-пиридо[4,3-d]пиримидин-5-оны, способ их получения, способ терапии с их помощью, компонент композиции и композиция на их основе, 2,4-диоксопиперидиновые соединения для их получения | |
| JP4778894B2 (ja) | 不安障害の治療方法 | |
| Albaugh et al. | Synthesis and Biological Evaluation of 7, 8, 9, 10-Tetrahydroimidazo [1, 2-c] pyrido [3, 4-e] pyrimdin-5 (6H)-ones as Functionally Selective Ligands of the Benzodiazepine Receptor Site on the GABAA Receptor | |
| JP2005503433A5 (enExample) | ||
| Vu et al. | Studies on adenosine A2A receptor antagonists: comparison of three core heterocycles | |
| WO2006097263A3 (de) | Kompatible solute enthaltende mittel zur oralen verwendung |