JP2006525796A - インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物 - Google Patents

インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物 Download PDF

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Publication number
JP2006525796A
JP2006525796A JP2006502644A JP2006502644A JP2006525796A JP 2006525796 A JP2006525796 A JP 2006525796A JP 2006502644 A JP2006502644 A JP 2006502644A JP 2006502644 A JP2006502644 A JP 2006502644A JP 2006525796 A JP2006525796 A JP 2006525796A
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seq
polypeptide
amino acid
nucleic acid
polynucleotide sequence
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JP2006525796A5 (enExample
Inventor
ルース アルノン,
スン−ホ ジオン,
バシャク カヤン,
タマル ベン−イエディディヤ,
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Yeda Research and Development Co Ltd
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Yeda Research and Development Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/11—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/322—2'-R Modification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
JP2006502644A 2003-02-27 2004-02-24 インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物 Pending JP2006525796A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44986303P 2003-02-27 2003-02-27
PCT/IL2004/000182 WO2004076621A2 (en) 2003-02-27 2004-02-24 Compositions of nucleic acids for treating and detecting influenza virus

Related Child Applications (1)

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JP2010180666A Division JP2010279385A (ja) 2003-02-27 2010-08-12 インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物

Publications (2)

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JP2006525796A true JP2006525796A (ja) 2006-11-16
JP2006525796A5 JP2006525796A5 (enExample) 2007-02-01

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JP2006502644A Pending JP2006525796A (ja) 2003-02-27 2004-02-24 インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物
JP2010180666A Pending JP2010279385A (ja) 2003-02-27 2010-08-12 インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物

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Country Status (7)

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US (3) US7786279B2 (enExample)
EP (1) EP1597350B1 (enExample)
JP (2) JP2006525796A (enExample)
KR (1) KR101130181B1 (enExample)
AU (1) AU2004215133B2 (enExample)
CA (1) CA2517074A1 (enExample)
WO (1) WO2004076621A2 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
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WO2009096581A1 (ja) * 2008-02-01 2009-08-06 Kunihiro Kaihatsu 膜融合阻害剤
JP2010279385A (ja) * 2003-02-27 2010-12-16 Yeda Res & Dev Co Ltd インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物
JP2012100636A (ja) * 2010-11-15 2012-05-31 National Institute Of Advanced Industrial Science & Technology 新型インフルエンザウイルスのヘマグルチニンに結合するアプタマー
JPWO2013183383A1 (ja) * 2012-06-04 2016-01-28 Necソリューションイノベータ株式会社 インフルエンザウイルスに結合する核酸分子およびその用途
US9801850B2 (en) 2009-07-31 2017-10-31 Osaka University Antibacterial agent
KR20210025861A (ko) * 2019-08-28 2021-03-10 성균관대학교산학협력단 바이러스 외피를 손상시키는 m2 단백질 유래 항바이러스 펩타이드 및 그의 용도

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EP1843158A1 (de) * 2006-04-05 2007-10-10 Micronas Holding GmbH Nachweissystem für Krankheitserreger
US8067532B2 (en) * 2007-01-19 2011-11-29 Kai Pharmaceuticals, Inc. Modifications of peptide compositions to increase stability and delivery efficiency
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SG190562A1 (en) 2008-04-18 2013-06-28 Vaxinnate Corp Deletion mutants of flagellin and methods of use
WO2010150982A2 (ko) * 2009-06-23 2010-12-29 한밭대학교 산학협력단 안전성이 뛰어난 인플루엔자 바이러스 백신용 재조합 헤마글루티닌 단백질 및 이를 함유하는 생분해성 plga 미립자의 제조 방법
KR101034490B1 (ko) 2009-06-23 2011-05-17 한밭대학교 산학협력단 생체 안전성이 뛰어난 인플루엔자 바이러스 백신용 항원성 에피토프로서의 재조합 헤마글루티닌 단백질
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JP5996837B2 (ja) * 2010-05-28 2016-09-21 小林製薬株式会社 インフルエンザウイルスの感染抑制剤
US20130064811A1 (en) * 2011-09-09 2013-03-14 International Business Machines Corporation Methods to Enhance Cancer Treatment
CN108424456B (zh) 2011-11-23 2022-04-26 医学免疫有限责任公司 特异于her3的结合分子及其用途
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
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BR112015020061A8 (pt) * 2013-02-22 2018-01-23 Wilex Ag composto alvo anidrase carbônica ix (caix) para tratamento de câncer, seus usos, composição farmcêutica, e método para diagnosticar, prognosticar e/ou classificar um câncer
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GB201419976D0 (en) * 2014-11-10 2014-12-24 Univ Newcastle Biomarkers for disease progression in melanoma
HK1242996A1 (zh) * 2014-11-14 2018-07-06 豪夫迈.罗氏有限公司 预测对vegf拮抗剂的响应
JP7095992B2 (ja) * 2014-12-08 2022-07-05 1グローブ バイオメディカル カンパニー, リミテッド 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用
EP3271397B1 (en) * 2015-03-18 2021-03-03 The Johns Hopkins University Inhibitory monoclonal antibody targeting potassium channel kcnk9
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
CA3015347A1 (en) 2016-02-24 2017-08-31 Visterra, Inc. Formulations of antibody molecules to influenza virus
KR101796277B1 (ko) * 2016-04-12 2017-11-13 앱클론(주) 안정성이 개선된 her2에 특이적으로 결합하는 항체
CN112334481A (zh) * 2018-06-11 2021-02-05 葛兰素史克消费保健(美国)控股有限责任公司 用于快速乙型流感诊断测试的抗体对
KR20200060969A (ko) 2018-11-23 2020-06-02 (주)셀트리온 인플루엔자 바이러스 질환을 치료하기 위한 투여 요법
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CN113773401B (zh) * 2021-09-15 2023-06-20 宜明昂科生物医药技术(上海)股份有限公司 靶向cd47和pd-l1的重组融合蛋白及其制备和用途

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010279385A (ja) * 2003-02-27 2010-12-16 Yeda Res & Dev Co Ltd インフルエンザウイルス感染を処置および検出するために有用な核酸分子、ポリペプチド、抗体、およびそれらを含有する組成物
WO2009096581A1 (ja) * 2008-02-01 2009-08-06 Kunihiro Kaihatsu 膜融合阻害剤
JP5579449B2 (ja) * 2008-02-01 2014-08-27 株式会社プロテクティア 膜融合阻害剤
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KR20210025861A (ko) * 2019-08-28 2021-03-10 성균관대학교산학협력단 바이러스 외피를 손상시키는 m2 단백질 유래 항바이러스 펩타이드 및 그의 용도
KR102393872B1 (ko) 2019-08-28 2022-05-04 엠브릭스 주식회사 바이러스 외피를 손상시키는 m2 단백질 유래 항바이러스 펩타이드 및 그의 용도

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US9029526B2 (en) 2015-05-12
EP1597350A2 (en) 2005-11-23
JP2010279385A (ja) 2010-12-16
US8357789B2 (en) 2013-01-22
EP1597350A4 (en) 2010-03-24
WO2004076621A2 (en) 2004-09-10
KR101130181B1 (ko) 2012-03-28
KR20050111336A (ko) 2005-11-24
CA2517074A1 (en) 2004-09-10
WO2004076621A3 (en) 2006-04-06
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US20070059806A1 (en) 2007-03-15
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