JP2006524511A5 - - Google Patents
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- Publication number
- JP2006524511A5 JP2006524511A5 JP2006513300A JP2006513300A JP2006524511A5 JP 2006524511 A5 JP2006524511 A5 JP 2006524511A5 JP 2006513300 A JP2006513300 A JP 2006513300A JP 2006513300 A JP2006513300 A JP 2006513300A JP 2006524511 A5 JP2006524511 A5 JP 2006524511A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- virus
- recombinant
- parainfluenza virus
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 241000700605 Viruses Species 0.000 claims 35
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 17
- 239000012634 fragment Substances 0.000 claims 15
- 241000351643 Metapneumovirus Species 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 238000012258 culturing Methods 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 210000002966 serum Anatomy 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 2
- 108091006027 G proteins Proteins 0.000 claims 2
- 102000030782 GTP binding Human genes 0.000 claims 2
- 108091000058 GTP-Binding Proteins 0.000 claims 2
- 241000712003 Human respirovirus 3 Species 0.000 claims 2
- 241000711955 Turkey rhinotracheitis virus Species 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 1
- 241000712005 Bovine respirovirus 3 Species 0.000 claims 1
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 1
- 241000342334 Human metapneumovirus Species 0.000 claims 1
- 101150039699 M2-1 gene Proteins 0.000 claims 1
- 101150103632 M2-2 gene Proteins 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 101710141454 Nucleoprotein Proteins 0.000 claims 1
- 102100034574 P protein Human genes 0.000 claims 1
- 101710181008 P protein Proteins 0.000 claims 1
- 241000711504 Paramyxoviridae Species 0.000 claims 1
- 101710177166 Phosphoprotein Proteins 0.000 claims 1
- 241000711904 Pneumoviridae Species 0.000 claims 1
- 108020004511 Recombinant DNA Proteins 0.000 claims 1
- 206010057190 Respiratory tract infections Diseases 0.000 claims 1
- 101001039853 Sonchus yellow net virus Matrix protein Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 241001493065 dsRNA viruses Species 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46618103P | 2003-04-25 | 2003-04-25 | |
| US49927403P | 2003-08-28 | 2003-08-28 | |
| US55093104P | 2004-03-05 | 2004-03-05 | |
| PCT/US2004/012723 WO2005027825A2 (en) | 2003-04-25 | 2004-04-23 | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011084567A Division JP2011167197A (ja) | 2003-04-25 | 2011-04-06 | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006524511A JP2006524511A (ja) | 2006-11-02 |
| JP2006524511A5 true JP2006524511A5 (enExample) | 2007-06-14 |
Family
ID=34381928
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513300A Pending JP2006524511A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| JP2011084567A Ceased JP2011167197A (ja) | 2003-04-25 | 2011-04-06 | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011084567A Ceased JP2011167197A (ja) | 2003-04-25 | 2011-04-06 | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20050142148A1 (enExample) |
| EP (1) | EP1622574A4 (enExample) |
| JP (2) | JP2006524511A (enExample) |
| KR (2) | KR20110097971A (enExample) |
| CN (1) | CN1813061B (enExample) |
| AU (1) | AU2004273776B2 (enExample) |
| CA (1) | CA2523657A1 (enExample) |
| MX (1) | MXPA05011268A (enExample) |
| WO (1) | WO2005027825A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| DK1351981T3 (da) * | 2001-01-19 | 2012-11-26 | Vironovative Bv | Et virus, der forårsager luftvejssygdom hos modtagelige pattedyr |
| JP4553589B2 (ja) | 2002-02-21 | 2010-09-29 | メディミューン，エルエルシー | 組換えパラインフルエンザウイルス発現系とメタニューモウイルスから得られる異種抗原を含むワクチン |
| CA2494485A1 (en) * | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| US7704720B2 (en) * | 2003-04-25 | 2010-04-27 | Medimmune, Llc | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| AU2006223138B2 (en) * | 2005-03-10 | 2012-04-05 | Medimmune, Llc | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| AU2006270225A1 (en) * | 2005-07-14 | 2007-01-25 | Mayo Foundation For Medical Education And Research | Paramyxoviridae virus preparations |
| EP2069485A4 (en) * | 2007-07-13 | 2011-05-25 | Medimmune Llc | PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION |
| US20090186050A1 (en) * | 2007-11-16 | 2009-07-23 | Fouchier Ron A M | Live attenuated metapneumovirus strains and their use in vaccine formulations and chimeric metapneumovirus strains |
| HRP20160859T1 (hr) | 2008-12-09 | 2016-09-23 | Novavax, Inc. | Modificirani proteini rsv f i postupci njihove upotrebe |
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| AU2010264686A1 (en) | 2009-06-24 | 2012-01-19 | Glaxosmithkline Biologicals S.A. | Vaccine |
| KR101073991B1 (ko) * | 2009-10-27 | 2011-10-21 | 대한민국 | 국내사육 닭에서 유행하는 신규한 ｂ형 조류메타뉴모바이러스 ｓｃ1509주 및 이의 용도 |
| AU2013201495B2 (en) * | 2011-09-30 | 2015-12-03 | Novavax, Inc. | Recombinant nanoparticle RSV F vaccine for respiratory syncytial virus |
| JP6132420B2 (ja) * | 2011-10-25 | 2017-05-24 | 国立大学法人岐阜大学 | 変異狂犬病ウイルス合成・増殖方法、並びに狂犬病ワクチン製剤 |
| GB201119032D0 (en) * | 2011-11-03 | 2011-12-14 | Isis Innovation | Multisomes: encapsulated droplet networks |
| US9695444B2 (en) | 2012-12-26 | 2017-07-04 | BioComo Inc. | Vaccine prepared utilizing human parainfluenza virus type 2 vector |
| WO2014160463A1 (en) | 2013-03-13 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prefusion rsv f proteins and their use |
| CN105229021A (zh) * | 2013-03-15 | 2016-01-06 | 加利福尼亚大学董事会 | 在哺乳动物中起抗病毒免疫作用的rna干扰 |
| CL2013002829A1 (es) | 2013-10-01 | 2014-04-04 | Univ Pontificia Catolica Chile | Formulacion inmunogenica que contiene bcg vivas recombinantes que expresan antigenos de metapneumovirus (hmpv) en una suspension que se prepara a partir de un liofilizado sin la necesidad de adjuvante; su uso farmaceutico; vacuna contra hmpv. |
| JP6589159B2 (ja) * | 2014-04-01 | 2019-10-16 | 共立製薬株式会社 | 新規ネコモルビリウイルス株、不活化ワクチン製剤、並びにネコモルビリウイルス感染症予防方法 |
| CN107406835A (zh) | 2015-01-20 | 2017-11-28 | 美利坚合众国,由健康及人类服务部部长代表 | 表达嵌合rsv/bpiv3f蛋白的重组人/牛副流感病毒3(b/hpiv3)及其用途 |
| WO2017041100A2 (en) | 2015-09-03 | 2017-03-09 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
| EP4349405A3 (en) | 2015-10-22 | 2024-06-19 | ModernaTX, Inc. | Respiratory virus vaccines |
| US11174292B2 (en) | 2016-03-29 | 2021-11-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Substitutions-modified prefusion RSV F proteins and their use |
| MA50335A (fr) | 2016-12-08 | 2020-08-19 | Modernatx Inc | Vaccins à acide nucléique contre des virus respiratoires |
| EP3554538A2 (en) | 2016-12-16 | 2019-10-23 | Institute for Research in Biomedicine | Novel recombinant prefusion rsv f proteins and uses thereof |
| EP3630173A1 (en) | 2017-05-29 | 2020-04-08 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing rsv g and its use |
| US12083228B2 (en) | 2017-07-24 | 2024-09-10 | Novavax, Inc. | Methods and compositions for treating respiratory disease |
| KR20250151575A (ko) | 2018-03-19 | 2025-10-21 | 노바백스, 인코포레이티드 | 다가 인플루엔자 나노입자 백신 |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| TWI708877B (zh) | 2019-10-18 | 2020-11-01 | 福懋興業股份有限公司 | 導電布及其製備方法與應用 |
| CN111961652A (zh) * | 2020-07-09 | 2020-11-20 | 温氏食品集团股份有限公司 | 一种禽偏肺病毒的无血清全悬浮培养方法及其在疫苗中的应用 |
| CA3216466A1 (en) | 2021-04-27 | 2022-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing sars-cov-2 spike protein and its use |
| CN113593639B (zh) * | 2021-08-05 | 2023-08-25 | 湖南大学 | 一种用于病毒基因组变异分析、监测方法和系统 |
| MX2024006506A (es) | 2021-11-30 | 2024-08-14 | Sanofi Pasteur Inc | Vacunas basadas en vectores virales de metapneumovirus humano. |
| AU2023264067A1 (en) * | 2022-05-02 | 2024-11-28 | The Regents Of The University Of California | Multicomponent systems for site-specific genome modifications |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5854037A (en) * | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
| US5166057A (en) * | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
| US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| US5869036A (en) * | 1995-12-08 | 1999-02-09 | St. Louis University | Live attenuated vaccines based on CP45 HPIV-3 strain and method to ensure attenuation in such vaccine |
| US6180398B1 (en) * | 1996-07-12 | 2001-01-30 | Virogeneitics Corporation | Two-step immunization procedure against the pyramyxoviridae family of viruses using recombinant virus and subunit protein preparation |
| US7192593B2 (en) * | 1997-05-23 | 2007-03-20 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens |
| US6656719B1 (en) | 1997-10-27 | 2003-12-02 | Merck & Co., Inc. | Serum-free, low-protein media for rotavirus vaccine production |
| US6146642A (en) * | 1998-09-14 | 2000-11-14 | Mount Sinai School Of Medicine, Of The City University Of New York | Recombinant new castle disease virus RNA expression systems and vaccines |
| EP1186667B1 (en) * | 1999-05-18 | 2007-07-18 | Dnavec Research Inc. | Envelope gene-deficient virus vector of paramyxoviridae |
| CN101392239A (zh) * | 1999-07-09 | 2009-03-25 | 美国政府健康及人类服务部 | 减毒的人-牛嵌合副流感病毒(piv)疫苗 |
| EP1103610A1 (en) * | 1999-11-26 | 2001-05-30 | Introgene B.V. | Production of vaccines from immortalised mammalian cell lines |
| DK1351981T3 (da) * | 2001-01-19 | 2012-11-26 | Vironovative Bv | Et virus, der forårsager luftvejssygdom hos modtagelige pattedyr |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| US7704509B2 (en) * | 2001-11-21 | 2010-04-27 | United States Of America | Recovery of recombinant human parainfluenza virus type 1 (HPIV1) from cDNA and use of recombinant HPIV1 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens |
| JP4553589B2 (ja) * | 2002-02-21 | 2010-09-29 | メディミューン，エルエルシー | 組換えパラインフルエンザウイルス発現系とメタニューモウイルスから得られる異種抗原を含むワクチン |
| US7704491B2 (en) * | 2003-02-28 | 2010-04-27 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant human metapneumovirus and its use |
| US7704720B2 (en) * | 2003-04-25 | 2010-04-27 | Medimmune, Llc | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| US20040229219A1 (en) * | 2003-04-30 | 2004-11-18 | Gallaher William R. | Method of inhibiting human metapneumovirus and human coronavirus in the prevention and treatment of severe acute respiratory syndrome (SARS) |
-
2004
- 2004-04-23 JP JP2006513300A patent/JP2006524511A/ja active Pending
- 2004-04-23 KR KR1020117016892A patent/KR20110097971A/ko not_active Abandoned
- 2004-04-23 EP EP04809338A patent/EP1622574A4/en not_active Withdrawn
- 2004-04-23 KR KR1020057020308A patent/KR101187955B1/ko not_active Expired - Fee Related
- 2004-04-23 WO PCT/US2004/012723 patent/WO2005027825A2/en not_active Ceased
- 2004-04-23 CA CA002523657A patent/CA2523657A1/en not_active Abandoned
- 2004-04-23 AU AU2004273776A patent/AU2004273776B2/en not_active Ceased
- 2004-04-23 US US10/831,781 patent/US20050142148A1/en not_active Abandoned
- 2004-04-23 MX MXPA05011268A patent/MXPA05011268A/es active IP Right Grant
- 2004-04-23 CN CN2004800178032A patent/CN1813061B/zh not_active Expired - Fee Related
-
2010
- 2010-10-20 US US12/908,351 patent/US20120045471A1/en not_active Abandoned
-
2011
- 2011-04-06 JP JP2011084567A patent/JP2011167197A/ja not_active Ceased
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