JP2006523194A - ビフェニルカルボン酸アミドｐ３８キナーゼ阻害剤 - Google Patents

ビフェニルカルボン酸アミドｐ３８キナーゼ阻害剤 Download PDF

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JP2006523194A
JP2006523194A JP2006505071A JP2006505071A JP2006523194A JP 2006523194 A JP2006523194 A JP 2006523194A JP 2006505071 A JP2006505071 A JP 2006505071A JP 2006505071 A JP2006505071 A JP 2006505071A JP 2006523194 A JP2006523194 A JP 2006523194A
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alkyl
optionally substituted
methyl
groups
hydrogen
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JP2006523194A5 (enExample
Inventor
アストン，ニコラ，マリー
バンボロー，ポール
ジョーンズ，キャサリン，ルイーズ
パテル，ヴィプルクマール，カンティバイ
スワンソン，スティーブン
ウォーカー，アン，ルイーズ
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スミスクライン ビーチャム コーポレーション
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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    • C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • Psychology (AREA)
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JP2006505071A 2003-04-09 2004-04-07 ビフェニルカルボン酸アミドｐ３８キナーゼ阻害剤 Pending JP2006523194A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0308186.6A GB0308186D0 (en) 2003-04-09 2003-04-09 Novel compounds
PCT/EP2004/003774 WO2004089874A1 (en) 2003-04-09 2004-04-07 Biphenyl carboxylic amide p38 kinase inhibitors

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JP2006523194A true JP2006523194A (ja) 2006-10-12
JP2006523194A5 JP2006523194A5 (enExample) 2007-05-31

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US (1) US7572790B2 (enExample)
EP (1) EP1608616A1 (enExample)
JP (1) JP2006523194A (enExample)
AU (1) AU2004228199A1 (enExample)
BR (1) BRPI0408727A (enExample)
CA (1) CA2521228A1 (enExample)
GB (1) GB0308186D0 (enExample)
MX (1) MXPA05010521A (enExample)
WO (1) WO2004089874A1 (enExample)
ZA (1) ZA200506919B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008515898A (ja) * 2004-10-05 2008-05-15 スミスクライン・ビーチャム・コーポレイション 新規化合物
JP2018538355A (ja) * 2015-09-30 2018-12-27 シイエスピイシイ・チョンチ・ファーマシューティカル・テクノロジー・（シーチアチョワン）・カンパニー・リミテッド ベンズアミド誘導体

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PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0124934D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124938D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124936D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124939D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124933D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124931D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124941D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
ES2295553T3 (es) * 2002-02-12 2008-04-16 Smithkline Beecham Corporation Derivados de nicotinamida utiles como inhibidores de p38.
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