JP2006521824A5 - - Google Patents

Download PDF

Info

Publication number
JP2006521824A5
JP2006521824A5 JP2006509580A JP2006509580A JP2006521824A5 JP 2006521824 A5 JP2006521824 A5 JP 2006521824A5 JP 2006509580 A JP2006509580 A JP 2006509580A JP 2006509580 A JP2006509580 A JP 2006509580A JP 2006521824 A5 JP2006521824 A5 JP 2006521824A5
Authority
JP
Japan
Prior art keywords
nucleic acid
polymerase inhibitor
polymerase
acid sequence
inhibitor according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006509580A
Other languages
English (en)
Japanese (ja)
Other versions
JP4567673B2 (ja
JP2006521824A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/010029 external-priority patent/WO2004090153A2/en
Publication of JP2006521824A publication Critical patent/JP2006521824A/ja
Publication of JP2006521824A5 publication Critical patent/JP2006521824A5/ja
Application granted granted Critical
Publication of JP4567673B2 publication Critical patent/JP4567673B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2006509580A 2003-04-01 2004-04-01 ポリメラーゼ阻害剤およびその使用方法 Expired - Lifetime JP4567673B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45967203P 2003-04-01 2003-04-01
PCT/US2004/010029 WO2004090153A2 (en) 2003-04-01 2004-04-01 Polymerase inhibitor and method of using same

Publications (3)

Publication Number Publication Date
JP2006521824A JP2006521824A (ja) 2006-09-28
JP2006521824A5 true JP2006521824A5 (https=) 2010-07-15
JP4567673B2 JP4567673B2 (ja) 2010-10-20

Family

ID=33159672

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006509580A Expired - Lifetime JP4567673B2 (ja) 2003-04-01 2004-04-01 ポリメラーゼ阻害剤およびその使用方法

Country Status (6)

Country Link
US (2) US7820808B2 (https=)
EP (1) EP1615942B1 (https=)
JP (1) JP4567673B2 (https=)
AU (1) AU2004227353B2 (https=)
CA (1) CA2521127C (https=)
WO (1) WO2004090153A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6830902B1 (en) * 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
ATE541055T1 (de) * 2004-10-18 2012-01-15 Univ Brandeis Reagenzien und verfahren zur verbesserung der reproduzierbarkeit und zur reduzierung des mispriming bei der pcr-amplifikation
US20070212704A1 (en) 2005-10-03 2007-09-13 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
US8012694B2 (en) * 2006-09-14 2011-09-06 Immutopics, Inc. Assay for the detection of phosphorylated PTH
US10865431B1 (en) * 2008-06-17 2020-12-15 Steven A Benner Polymerase incorporation of non-standard nucleotides
CA2688174C (en) * 2008-12-19 2018-08-07 F. Hoffmann-La Roche Ag Dry composition of reaction compounds with stabilized polymerase
AU2010224100B2 (en) * 2009-03-12 2015-10-22 Brandeis University Reagents and methods for PCR
CA2779689A1 (en) * 2009-11-06 2011-05-12 Enzymatics, Inc. Composition and method for synthesizing a deoxyribonucleotide chain using a double stranded nucleic acid complex with a thermostable polymerase
JP7106461B2 (ja) 2016-06-07 2022-07-26 セファイド 熱安定性ポリメラーゼ阻害剤組成物及び方法
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
EP3818170A4 (en) * 2018-07-02 2022-03-09 Swift Biosciences, Inc. Temperature controlled dna polymerase inhibitors
JP2023531027A (ja) * 2020-06-22 2023-07-20 ▲蘇▼州新海生物科技股▲ふん▼有限公司 核酸リガンド、およびその使用

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US5470974A (en) 1985-03-15 1995-11-28 Neu-Gene Development Group Uncharged polynucleotide-binding polymers
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4996143A (en) 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
IL86164A0 (en) 1987-04-28 1988-11-15 Tamir Biotechnology Ltd Improved dna probes
JPH0344560Y2 (https=) 1987-08-24 1991-09-19
WO1989002921A1 (en) 1987-09-22 1989-04-06 Temple University Artificial dna base pair analogues
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US6444798B1 (en) 1988-06-06 2002-09-03 Steven Albert Benner Chimeras of sulfur-linked oligonucleotide analogs and DNA and RNA
GB8827160D0 (en) 1988-11-21 1988-12-29 Apothekernes Lab Detection & quantitative determination of rna & dna
GB8902689D0 (en) 1989-02-07 1989-03-30 Ici Plc Assay method
US5856092A (en) 1989-02-13 1999-01-05 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
GB8920097D0 (en) 1989-09-06 1989-10-18 Ici Plc Amplification processes
US6007984A (en) 1989-11-01 1999-12-28 Zeneca Limited Detection of DNA/RNA by fluorescence polarization
US5412088A (en) 1989-11-20 1995-05-02 Rutgers, The State University 6-O-substituted guanosine derivatives
US5693502A (en) 1990-06-11 1997-12-02 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5874557A (en) 1990-06-11 1999-02-23 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5763173A (en) 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5552541A (en) 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides
US5177064A (en) 1990-07-13 1993-01-05 University Of Florida Targeted drug delivery via phosphonate derivatives
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6037120A (en) 1995-10-12 2000-03-14 Benner; Steven Albert Recognition of oligonucleotides containing non-standard base pairs
US5432272A (en) 1990-10-09 1995-07-11 Benner; Steven A. Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
US6140496A (en) 1990-10-09 2000-10-31 Benner; Steven Albert Precursors for deoxyribonucleotides containing non-standard nucleosides
US5965364A (en) 1990-10-09 1999-10-12 Benner; Steven Albert Method for selecting functional deoxyribonucleotide derivatives
DK0515660T3 (da) 1990-12-21 1997-07-28 Hoffmann La Roche HLA-DQbeta-DNA-typebestemmelse
DE4129653A1 (de) 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5958784A (en) 1992-03-25 1999-09-28 Benner; Steven Albert Predicting folded structures of proteins
AU3933393A (en) 1993-03-17 1994-10-11 City Of Hope Nucleic acid sequences having single stranded ends
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
WO1995021271A1 (en) 1994-02-07 1995-08-10 Molecular Tool, Inc. Ligase/polymerase-mediated genetic bit analysistm of single nucleotide polymorphisms and its use in genetic analysis
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5565340A (en) 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US6183967B1 (en) 1995-06-07 2001-02-06 Nexstar Pharmaceuticals Nucleic acid ligand inhibitors to DNA polymerases
US6020130A (en) 1995-06-07 2000-02-01 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands that bind to and inhibit DNA polymerases
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US5705621A (en) 1995-11-17 1998-01-06 Isis Pharmaceuticals, Inc. Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
US5780233A (en) 1996-06-06 1998-07-14 Wisconsin Alumni Research Foundation Artificial mismatch hybridization
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
US6482590B1 (en) 1996-12-20 2002-11-19 Aventis Behring Gmbh Method for polynucleotide amplification
US7101672B2 (en) 1998-05-05 2006-09-05 Third Wave Technologies, Inc. Target-dependent reactions using structure-bridging oligonucleotides
JP4185185B2 (ja) 1997-05-08 2008-11-26 征夫 軽部 部分二重鎖dnaを利用したdnaの検出方法
US5928869A (en) 1997-05-30 1999-07-27 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
JP4502502B2 (ja) 1997-10-28 2010-07-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア フローサイトメトリーを用いるdna多型の同定方法
GB9725197D0 (en) 1997-11-29 1998-01-28 Secr Defence Detection system
US6046807A (en) 1998-05-14 2000-04-04 Luminex Corporation Diode laser based measurement apparatus
EP1090293B2 (en) 1998-06-24 2019-01-23 Illumina, Inc. Decoding of array sensors with microspheres
US6200757B1 (en) 1999-01-19 2001-03-13 Dade Behring Inc. Method for controlling the extension of an oligonucleotide
US6274353B1 (en) 1999-09-22 2001-08-14 Genecopoeia, Inc. Method and compositions for improved polynucleotide synthesis
US6528254B1 (en) 1999-10-29 2003-03-04 Stratagene Methods for detection of a target nucleic acid sequence
US6509157B1 (en) 1999-11-05 2003-01-21 Roche Molecular Systems, Inc 3 blocked nucleic acid amplification primers
AU2001229576A1 (en) 2000-01-15 2001-07-24 Genelabs Technologies, Inc. Nucleic acid binding site assay and selection method
WO2001075139A1 (en) 2000-04-03 2001-10-11 Biolink Partners, Inc. Reversible chemical modification of nucleic acids and improved method for nucleic acid hybridization
AU7125401A (en) 2000-05-19 2001-12-03 David J Marshall Materials and methods for detection of nucleic acids
AU1317502A (en) 2000-10-14 2002-04-29 Eragen Biosciences Inc Solid support assay systems and methods utilizing non-standard bases
EP1456394B2 (en) * 2001-11-28 2011-04-27 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
US20030194705A1 (en) 2002-03-01 2003-10-16 Schroth Gary P. Methods of using unnatural nucleobases for decoding
US7282333B2 (en) 2003-10-20 2007-10-16 Promega Corporation Methods and compositions for nucleic acid analysis

Similar Documents

Publication Publication Date Title
CN107488710B (zh) 一种Cas蛋白的用途及靶标核酸分子的检测方法和试剂盒
US20090098612A1 (en) Method of amplifying a target nucleic acid by rolling circle amplification
ATE394410T1 (de) Hochspezifische primer, amplifizierungsverfahren und kits
CA2532160A1 (en) Methods of genotyping using differences in melting temperature
JP2011500092A5 (https=)
JP2006521824A5 (https=)
JP2022535584A (ja) 核酸増幅及び/又は検出用方法及び試薬
JP2005518215A5 (https=)
JP2017504360A5 (https=)
JP2012520080A5 (https=)
JP2009511056A5 (https=)
JPH06510669A (ja) 核酸伸長検定
JP2024531728A5 (https=)
JP2017537658A5 (https=)
JP2005511055A5 (https=)
CN116134150A (zh) 病原体特异性核酸片段及其应用
JP2021503903A5 (https=)
JP2001521765A5 (https=)
JP2023540177A5 (https=)
DE60332775D1 (de) Dopplezweck -Primer und -Proben für verbesserte Hybridisierungsassays durch Zerstörung von Sekundärstrukturen
JP2013524841A (ja) 一本鎖オーバーハングを有する二本鎖核酸を生成するための方法
EP3040423A3 (en) Microrna and uses thereof
JP2005505289A5 (https=)
KR20140123858A (ko) 폴리뉴클레오티드 및 그의 용도
JP2013509885A (ja) 熱安定性ポリメラーゼとともに二本鎖核酸複合体を用いてデオキシリボヌクレオチド鎖を合成するための組成物および方法