JP2009511056A5 - - Google Patents
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- JP2009511056A5 JP2009511056A5 JP2008535692A JP2008535692A JP2009511056A5 JP 2009511056 A5 JP2009511056 A5 JP 2009511056A5 JP 2008535692 A JP2008535692 A JP 2008535692A JP 2008535692 A JP2008535692 A JP 2008535692A JP 2009511056 A5 JP2009511056 A5 JP 2009511056A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- mrej type
- detection
- nos
- primers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000001514 detection method Methods 0.000 claims 75
- 239000000523 sample Substances 0.000 claims 67
- 238000000034 method Methods 0.000 claims 47
- 108091034117 Oligonucleotide Proteins 0.000 claims 13
- 230000003321 amplification Effects 0.000 claims 5
- 238000003199 nucleic acid amplification method Methods 0.000 claims 5
- 108091093088 Amplicon Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 238000000137 annealing Methods 0.000 claims 2
- 239000013611 chromosomal DNA Substances 0.000 claims 2
- 238000005096 rolling process Methods 0.000 claims 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 238000001712 DNA sequencing Methods 0.000 claims 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 108010066717 Q beta Replicase Proteins 0.000 claims 1
- 241000239226 Scorpiones Species 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 238000000246 agarose gel electrophoresis Methods 0.000 claims 1
- 238000004737 colorimetric analysis Methods 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 238000002866 fluorescence resonance energy transfer Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 101150008979 mecA gene Proteins 0.000 claims 1
- 229960003085 meticillin Drugs 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 230000010287 polarization Effects 0.000 claims 1
- 238000004313 potentiometry Methods 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/248,438 | 2005-10-11 | ||
| US11/248,438 US7838221B2 (en) | 2005-10-11 | 2005-10-11 | Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) |
| PCT/US2006/039996 WO2007044873A2 (en) | 2005-10-11 | 2006-10-10 | Sequences for detection and identification of methicillin-resistant staphylococcus aureus (mrsa) of mrej types xi to xx |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012157771A Division JP5706855B2 (ja) | 2005-10-11 | 2012-07-13 | ＭＲＥＪタイプｘｉ〜ｘｘのメチシリン耐性黄色ブドウ球菌（ＭＲＳＡ）を検出および同定するための配列 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009511056A JP2009511056A (ja) | 2009-03-19 |
| JP2009511056A5 true JP2009511056A5 (https=) | 2009-11-26 |
| JP5214454B2 JP5214454B2 (ja) | 2013-06-19 |
Family
ID=37911412
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008535692A Active JP5214454B2 (ja) | 2005-10-11 | 2006-10-10 | ＭＲＥＪタイプｘｉ〜ｘｘのメチシリン耐性黄色ブドウ球菌（ＭＲＳＡ）を検出および同定するための配列 |
| JP2012157771A Active JP5706855B2 (ja) | 2005-10-11 | 2012-07-13 | ＭＲＥＪタイプｘｉ〜ｘｘのメチシリン耐性黄色ブドウ球菌（ＭＲＳＡ）を検出および同定するための配列 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012157771A Active JP5706855B2 (ja) | 2005-10-11 | 2012-07-13 | ＭＲＥＪタイプｘｉ〜ｘｘのメチシリン耐性黄色ブドウ球菌（ＭＲＳＡ）を検出および同定するための配列 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7838221B2 (https=) |
| EP (8) | EP2322930B1 (https=) |
| JP (2) | JP5214454B2 (https=) |
| AT (1) | ATE496143T1 (https=) |
| AU (1) | AU2006302044B2 (https=) |
| CA (3) | CA3113401C (https=) |
| DE (1) | DE602006019757D1 (https=) |
| DK (5) | DK2325644T3 (https=) |
| ES (7) | ES2904841T3 (https=) |
| WO (1) | WO2007044873A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2348042A1 (en) * | 2001-06-04 | 2002-12-04 | Ann Huletsky | Sequences for detection and identification of methicillin-resistant staphylococcus aureus |
| US11834720B2 (en) * | 2005-10-11 | 2023-12-05 | Geneohm Sciences, Inc. | Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx |
| DE602007006478D1 (de) | 2006-05-12 | 2010-06-24 | Cepheid Sunnyvale | Erkennung der verbindung einer dna-rekombination |
| JP2010512799A (ja) | 2006-12-19 | 2010-04-30 | ジーンオーム サイエンシーズ、インク． | 黄色ブドウ球菌の検出およびメチシリン耐性黄色ブドウ球菌の特定 |
| US8535888B2 (en) * | 2006-12-29 | 2013-09-17 | Mayo Foundation For Medical Education And Research | Compositions and methods for detecting methicillin-resistant S. aureus |
| CA2684570A1 (en) | 2007-04-19 | 2008-10-30 | Molecular Detection Inc. | Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria |
| EP2183391A4 (en) * | 2007-07-31 | 2010-10-27 | Quest Diagnostics Invest Inc | DETECTION OF METHICILLIN-RESISTANT AND METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS IN BIOLOGICAL SAMPLES |
| US20100304366A1 (en) * | 2007-11-13 | 2010-12-02 | Wu Ling-Chuan Chen | Methods for Determining Virulence and Invasiveness Among Various Staphylococcus Aureus Strains |
| ES2686677T3 (es) * | 2007-12-21 | 2018-10-19 | Biomerieux Sa | Detección de Staphylococcus aureus resistente a meticilina |
| US20110008303A1 (en) * | 2008-03-17 | 2011-01-13 | Cedars-Sinai Medical Center | Methods for treatment and prevention of mrsa/mssa |
| AR077841A1 (es) | 2009-08-11 | 2011-09-28 | Univ Brandeis | Metodos kits y composiciones de deteccion de acido nucleico a multiples temperaturas, con sonda unica |
| JP5907880B2 (ja) | 2009-11-13 | 2016-04-26 | ベックマン コールター， インコーポレイテッド | クラスタリングを用いて生物学的持続状態の存在を検出するためのシステムおよび方法 |
| US8715936B2 (en) | 2010-01-13 | 2014-05-06 | Medical Diagnostic Laboratories, Llc | Method of determining types I, II, III, IV or V or methicillin-resistant Staphylococcus aureus (MRSA) in a biological sample |
| US20140030712A1 (en) * | 2011-02-01 | 2014-01-30 | Baylor College Of Medicine | Genomic approach to the identification of biomarkers for antibiotic resistance and susceptibility in clinical isolates of bacterial pathogens |
| ES2537189T3 (es) | 2011-05-24 | 2015-06-03 | Elitech Holding B.V. | Detección de estafilococos áureos resistentes a la meticilina |
| US9394573B2 (en) | 2011-12-23 | 2016-07-19 | Biomerieux S.A. | Detection of mecA variant strains of methicillin-resistant Staphylococcus aureus |
| WO2013112755A1 (en) | 2012-01-24 | 2013-08-01 | The Trustees Of Columbia University In The City Of New York | Field optimized assay devices, methods, and systems |
| BR112014024888B1 (pt) | 2012-04-06 | 2023-05-16 | Geneohm Sciences Canada, Inc | Composição e método para detectar staphylococcus aureus resistente à meticilina (sarm) |
| WO2016025698A1 (en) | 2014-08-13 | 2016-02-18 | The Trustees Of Columbia University In The City Of New York | Diagnostic devices, systems, and methods |
| EP3371320A4 (en) | 2015-11-04 | 2018-12-05 | The Translational Genomics Research Institute | Systems and methods of diagnosing and characterizing infections |
| JP6997287B2 (ja) | 2017-07-10 | 2022-02-03 | ジェン－プローブ・インコーポレーテッド | 試料割り当てパラメータを使用した核酸増幅のための分析システムおよび方法 |
| US11859257B2 (en) | 2017-08-11 | 2024-01-02 | Gen-Probe Incorporated | Compositions and methods for detecting Staphylococcus aureus |
| EP3746225B1 (en) | 2018-01-29 | 2024-10-30 | Gen-Probe Incorporated | Analytical systems and methods |
| JP7470095B2 (ja) | 2018-07-10 | 2024-04-17 | ジェン－プローブ・インコーポレーテッド | 核酸を検出および定量するための方法およびシステム |
| WO2021046336A1 (en) * | 2019-09-06 | 2021-03-11 | Teleflex Medical Incorporated | Oligonucleotides for real-time determining the identification and antibiotic resistance of pathogenic microorganisms |
| ES2991814T3 (es) | 2019-12-27 | 2024-12-05 | Hoffmann La Roche | Composiciones y procedimientos para detectar Staphylococcus aureus resistente a la meticilina |
| US20250011882A1 (en) | 2021-11-22 | 2025-01-09 | Roche Molecular Systems, Inc. | Compositions and Methods for Detecting vanA and/or vanB Genes Associated with Multidrug Resistance |
| EP4289972A1 (en) | 2022-06-09 | 2023-12-13 | Congen Biotechnologie GmbH | Method for detecting methicillin resistant staphylococcus aureus |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| WO1992005281A1 (fr) | 1990-09-14 | 1992-04-02 | Chugai Seiyaku Kabushiki Kaisha | Procede de detection de staphylococcus aureus resistant au mesitylene-cephem |
| JPH0549477A (ja) * | 1991-08-05 | 1993-03-02 | Wakunaga Pharmaceut Co Ltd | スタフイロコツカス属細菌類の検出 |
| CA2075423A1 (en) | 1991-08-13 | 1993-02-14 | Paul Luther Skatrud | Rapid method for detection of methicillin resistant staphylococci |
| DE4338119A1 (de) | 1993-11-08 | 1995-05-11 | Bayer Ag | Spezifische Gensonden und Verfahren zum quantitativen Nachweis von methicillinresistenten Staphylococcen |
| US5496706A (en) * | 1993-12-17 | 1996-03-05 | Helsinki University Licensing, Ltd. | Methods and materials for the detection of Staphylococcus aureus |
| US6090592A (en) * | 1994-08-03 | 2000-07-18 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid on supports |
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| US5702895A (en) * | 1995-01-19 | 1997-12-30 | Wakunaga Seiyaku Kabushiki Kaisha | Method and kit for detecting methicillin-resistant Staphylococcus aureus |
| JP3957338B2 (ja) * | 1996-02-23 | 2007-08-15 | 株式会社カイノス | 診断薬 |
| US6117635A (en) * | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US5866366A (en) * | 1997-07-01 | 1999-02-02 | Smithkline Beecham Corporation | gidB |
| JPH1156371A (ja) | 1997-08-22 | 1999-03-02 | Kainosu:Kk | 同定方法 |
| US6117986A (en) * | 1998-06-10 | 2000-09-12 | Intergen Company, L.P. | Pyrimidines linked to a quencher |
| EP1246935B1 (en) | 1999-09-28 | 2013-08-14 | Geneohm Sciences Canada Inc. | Highly conserved genes and their use to generate probes and primers for detection of microorganisms |
| CA2348042A1 (en) * | 2001-06-04 | 2002-12-04 | Ann Huletsky | Sequences for detection and identification of methicillin-resistant staphylococcus aureus |
| DE60304481T8 (de) | 2003-11-07 | 2007-03-08 | Federal Rep. of Germany repr.by the Ministry of Health & Soc.Security, the latter repr. by the Pres. of the Robert Koch Inst. | Verfahren zur Identifizierung von Methicilin resistente Staphylococcus aureus (MRSA) |
| US20060039996A1 (en) | 2004-03-17 | 2006-02-23 | Palmer Craig R | Method for treating sepsis |
| US11834720B2 (en) * | 2005-10-11 | 2023-12-05 | Geneohm Sciences, Inc. | Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx |
-
2005
- 2005-10-11 US US11/248,438 patent/US7838221B2/en active Active
-
2006
- 2006-10-10 ES ES10016031T patent/ES2904841T3/es active Active
- 2006-10-10 EP EP10016074.6A patent/EP2322930B1/en active Active
- 2006-10-10 DK DK10016072.0T patent/DK2325644T3/da active
- 2006-10-10 DK DK10016031.6T patent/DK2325643T3/da active
- 2006-10-10 ES ES10016074T patent/ES2891324T3/es active Active
- 2006-10-10 CA CA3113401A patent/CA3113401C/en active Active
- 2006-10-10 EP EP10016020.9A patent/EP2325647B1/en not_active Revoked
- 2006-10-10 EP EP10016072.0A patent/EP2325644B1/en not_active Revoked
- 2006-10-10 AT AT06825875T patent/ATE496143T1/de active
- 2006-10-10 DK DK10016074.6T patent/DK2322930T3/da active
- 2006-10-10 CA CA2625072A patent/CA2625072C/en active Active
- 2006-10-10 ES ES06825875T patent/ES2358871T3/es active Active
- 2006-10-10 EP EP10016073.8A patent/EP2325645B1/en not_active Revoked
- 2006-10-10 CA CA2963707A patent/CA2963707C/en active Active
- 2006-10-10 ES ES10016073T patent/ES2824902T3/es active Active
- 2006-10-10 DK DK10016020.9T patent/DK2325647T3/da active
- 2006-10-10 EP EP10016031.6A patent/EP2325643B1/en not_active Revoked
- 2006-10-10 DK DK10016073.8T patent/DK2325645T3/da active
- 2006-10-10 ES ES10016020T patent/ES2891323T3/es active Active
- 2006-10-10 EP EP06825875A patent/EP1934613B1/en not_active Revoked
- 2006-10-10 ES ES10016072T patent/ES2858823T3/es active Active
- 2006-10-10 EP EP21211005.0A patent/EP4043882A1/en active Pending
- 2006-10-10 EP EP10016019.1A patent/EP2325646B1/en not_active Revoked
- 2006-10-10 WO PCT/US2006/039996 patent/WO2007044873A2/en not_active Ceased
- 2006-10-10 AU AU2006302044A patent/AU2006302044B2/en active Active
- 2006-10-10 ES ES10016019T patent/ES2733864T3/es active Active
- 2006-10-10 DE DE602006019757T patent/DE602006019757D1/de active Active
- 2006-10-10 JP JP2008535692A patent/JP5214454B2/ja active Active
-
2012
- 2012-07-13 JP JP2012157771A patent/JP5706855B2/ja active Active
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