JP2006518331A5 - - Google Patents
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- Publication number
- JP2006518331A5 JP2006518331A5 JP2004552615A JP2004552615A JP2006518331A5 JP 2006518331 A5 JP2006518331 A5 JP 2006518331A5 JP 2004552615 A JP2004552615 A JP 2004552615A JP 2004552615 A JP2004552615 A JP 2004552615A JP 2006518331 A5 JP2006518331 A5 JP 2006518331A5
- Authority
- JP
- Japan
- Prior art keywords
- core
- protein
- polynucleotide
- hcv
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 claims 19
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 102000004169 proteins and genes Human genes 0.000 claims 15
- 101710132601 Capsid protein Proteins 0.000 claims 14
- 108091033319 polynucleotide Proteins 0.000 claims 14
- 102000040430 polynucleotide Human genes 0.000 claims 14
- 239000002157 polynucleotide Substances 0.000 claims 14
- 229960005486 vaccine Drugs 0.000 claims 7
- 108700039791 Hepatitis C virus nucleocapsid Proteins 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 101710144111 Non-structural protein 3 Proteins 0.000 claims 2
- 101800001554 RNA-directed RNA polymerase Proteins 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 1
- 101800001019 Non-structural protein 4B Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0226722.7A GB0226722D0 (en) | 2002-11-15 | 2002-11-15 | Vaccine |
| PCT/EP2003/012793 WO2004046175A1 (en) | 2002-11-15 | 2003-11-13 | Vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006518331A JP2006518331A (ja) | 2006-08-10 |
| JP2006518331A5 true JP2006518331A5 (enExample) | 2006-09-21 |
Family
ID=9947928
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552621A Pending JP2006524181A (ja) | 2002-11-15 | 2003-11-13 | ワクチン |
| JP2004552615A Pending JP2006518331A (ja) | 2002-11-15 | 2003-11-13 | ワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552621A Pending JP2006524181A (ja) | 2002-11-15 | 2003-11-13 | ワクチン |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US20060135451A1 (enExample) |
| EP (2) | EP1560844A1 (enExample) |
| JP (2) | JP2006524181A (enExample) |
| KR (2) | KR20050085009A (enExample) |
| CN (2) | CN1738834A (enExample) |
| AR (1) | AR041964A1 (enExample) |
| AU (2) | AU2003288084A1 (enExample) |
| BR (2) | BR0316291A (enExample) |
| CA (2) | CA2504715A1 (enExample) |
| CO (1) | CO5700833A2 (enExample) |
| GB (1) | GB0226722D0 (enExample) |
| IS (2) | IS7830A (enExample) |
| MA (2) | MA27700A1 (enExample) |
| MX (2) | MXPA05005203A (enExample) |
| NO (2) | NO20052149L (enExample) |
| NZ (2) | NZ539998A (enExample) |
| PL (2) | PL376967A1 (enExample) |
| RU (2) | RU2363492C2 (enExample) |
| TW (1) | TW200502246A (enExample) |
| WO (2) | WO2004046176A1 (enExample) |
| ZA (2) | ZA200503803B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022830B2 (en) * | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| GB0226722D0 (en) * | 2002-11-15 | 2002-12-24 | Glaxo Group Ltd | Vaccine |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| AU2005295317B2 (en) * | 2004-10-18 | 2011-10-13 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| ES2551113T3 (es) * | 2006-01-04 | 2015-11-16 | Glaxosmithkline Biologicals S.A. | Proteína E1E2 del VHC adyuvantada con MF59 más vector de alfavirus que codifica E1E2 del VHC para provocar linfocitos T específicos del VHC |
| CA2645177A1 (en) * | 2006-03-09 | 2007-09-13 | Transgene S.A. | Hepatitis c virus non structural fusion protein |
| WO2008094200A2 (en) * | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc | Chimeric virus-like particles |
| WO2008094197A2 (en) | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
| KR100759106B1 (ko) * | 2007-02-14 | 2007-09-19 | 이화여자대학교 산학협력단 | 초미세 전기기계 시스템 미러에서 미러 판을 정전 구동부와 결합하는 방법 |
| EP2185195A2 (en) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen platform |
| RU2370776C2 (ru) * | 2007-11-08 | 2009-10-20 | Общество с ограниченной ответственностью "Диагностические Центры "Алкор Био" | Набор антигенов для раздельного выявления антител к структурным и неструктурным белкам вируса гепатита с |
| US9758794B2 (en) | 2008-04-22 | 2017-09-12 | Rutgers, The State University Of New Jersey | HCV E2 construct compositions and methods |
| CA2722423A1 (en) * | 2008-04-22 | 2009-10-29 | Rutgers, The State University | Hcv e2 construct compositions and methods |
| US20120100170A1 (en) * | 2008-07-24 | 2012-04-26 | Lauer Peter M | Compositions and methods for the treatment of hepatitis c |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| CN101748151B (zh) * | 2008-12-19 | 2012-10-17 | 深圳市源兴生物医药科技有限公司 | 一种重组人丙肝病毒抗原腺病毒载体及其应用 |
| JP2010168288A (ja) * | 2009-01-20 | 2010-08-05 | Yokohama City Univ | 最適化した抗原遺伝子の使用によるウイルスワクチンの免疫原性の増強 |
| WO2011056899A2 (en) | 2009-11-03 | 2011-05-12 | Ligocyte Pharmaceuticals, Inc. | Chimeric rsv-f polypeptide and lentivirus or alpha-retrovirus gag-based vlps |
| CN102233137B (zh) * | 2010-04-30 | 2013-02-20 | 北京凯因科技股份有限公司 | 一种用于治疗乙型肝炎的重组质粒dna疫苗组合物 |
| WO2014127478A1 (en) * | 2013-02-21 | 2014-08-28 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Vaccine composition |
| CN119504957B (zh) * | 2025-01-16 | 2025-04-25 | 中山大学 | 一种佐剂及其在制备疫苗中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945050A (en) * | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| IE62868B1 (en) * | 1987-11-18 | 1995-03-08 | Chiron Corp | Hepatitis C virus |
| CA2070952A1 (en) * | 1991-06-11 | 1992-12-12 | Makoto Seki | Gene of hepatitis c virus or fragment thereof, polypeptide encoded by the same |
| US6297048B1 (en) * | 1992-02-04 | 2001-10-02 | Chiron Corporation | Hepatitis therapeutics |
| DE69533167D1 (de) * | 1994-10-05 | 2004-07-22 | Apollon Inc | Impfstoffe gegen den hepatitis b und c virus |
| IL118364A0 (en) * | 1995-05-22 | 1996-09-12 | Bionova Corp | A hepatitis C virus-derived composition methods for the preparation thereof and assays for the detection of hepatitis C virus |
| JP2002500502A (ja) * | 1996-06-11 | 2002-01-08 | メルク エンド カンパニー インコーポレーテッド | 合成ｃ型肝炎遺伝子 |
| US7052696B2 (en) * | 1998-07-10 | 2006-05-30 | The United States Of America As Represented By The Department Of Health And Human Services | Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins |
| AU774887B2 (en) * | 1999-07-09 | 2004-07-08 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins |
| US6562346B1 (en) * | 1999-10-27 | 2003-05-13 | Chiron Corporation | Activation of HCV-specific T cells |
| EP1233982B1 (en) * | 1999-11-24 | 2007-10-24 | Novartis Vaccines and Diagnostics, Inc. | Novel hcv non-structural polypeptide |
| FI116851B (fi) * | 2001-05-03 | 2006-03-15 | Fit Biotech Oyj Plc | Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita |
| DE10143490C2 (de) * | 2001-09-05 | 2003-12-11 | Gsf Forschungszentrum Umwelt | Rekombinantes MVA mit der Fähigkeit zur Expression von HCV Struktur-Antigenen |
| GB0226722D0 (en) * | 2002-11-15 | 2002-12-24 | Glaxo Group Ltd | Vaccine |
-
2002
- 2002-11-15 GB GBGB0226722.7A patent/GB0226722D0/en not_active Ceased
-
2003
- 2003-11-13 RU RU2005113691/13A patent/RU2363492C2/ru not_active IP Right Cessation
- 2003-11-13 BR BR0316291-5A patent/BR0316291A/pt not_active IP Right Cessation
- 2003-11-13 AR ARP030104193A patent/AR041964A1/es unknown
- 2003-11-13 JP JP2004552621A patent/JP2006524181A/ja active Pending
- 2003-11-13 WO PCT/EP2003/012830 patent/WO2004046176A1/en not_active Ceased
- 2003-11-13 US US10/534,774 patent/US20060135451A1/en not_active Abandoned
- 2003-11-13 JP JP2004552615A patent/JP2006518331A/ja active Pending
- 2003-11-13 AU AU2003288084A patent/AU2003288084A1/en not_active Abandoned
- 2003-11-13 NZ NZ539998A patent/NZ539998A/en unknown
- 2003-11-13 BR BR0316244-3A patent/BR0316244A/pt not_active IP Right Cessation
- 2003-11-13 PL PL376967A patent/PL376967A1/pl not_active Application Discontinuation
- 2003-11-13 RU RU2005113692/13A patent/RU2323744C2/ru not_active IP Right Cessation
- 2003-11-13 WO PCT/EP2003/012793 patent/WO2004046175A1/en not_active Ceased
- 2003-11-13 CN CNA2003801088698A patent/CN1738834A/zh active Pending
- 2003-11-13 KR KR1020057008793A patent/KR20050085009A/ko not_active Ceased
- 2003-11-13 US US10/535,047 patent/US20060246090A1/en not_active Abandoned
- 2003-11-13 MX MXPA05005203A patent/MXPA05005203A/es not_active Application Discontinuation
- 2003-11-13 PL PL376882A patent/PL376882A1/pl not_active Application Discontinuation
- 2003-11-13 MX MXPA05005202A patent/MXPA05005202A/es active IP Right Grant
- 2003-11-13 NZ NZ539999A patent/NZ539999A/en unknown
- 2003-11-13 KR KR1020057008794A patent/KR20050085010A/ko not_active Ceased
- 2003-11-13 CN CNA200380108865XA patent/CN1738833A/zh active Pending
- 2003-11-13 EP EP03779938A patent/EP1560844A1/en not_active Withdrawn
- 2003-11-13 CA CA002504715A patent/CA2504715A1/en not_active Abandoned
- 2003-11-13 EP EP03779952A patent/EP1560845A1/en not_active Withdrawn
- 2003-11-13 TW TW092131802A patent/TW200502246A/zh unknown
- 2003-11-13 AU AU2003288072A patent/AU2003288072A1/en not_active Abandoned
- 2003-11-13 CA CA002504654A patent/CA2504654A1/en not_active Abandoned
-
2005
- 2005-04-28 IS IS7830A patent/IS7830A/is unknown
- 2005-04-28 IS IS7831A patent/IS7831A/is unknown
- 2005-05-02 NO NO20052149A patent/NO20052149L/no not_active Application Discontinuation
- 2005-05-02 NO NO20052136A patent/NO20052136L/no not_active Application Discontinuation
- 2005-05-11 ZA ZA200503803A patent/ZA200503803B/en unknown
- 2005-05-11 ZA ZA200503802A patent/ZA200503802B/en unknown
- 2005-05-16 MA MA28285A patent/MA27700A1/fr unknown
- 2005-05-16 MA MA28284A patent/MA27699A1/fr unknown
- 2005-06-10 CO CO05056623A patent/CO5700833A2/es not_active Application Discontinuation
-
2008
- 2008-07-17 US US12/174,715 patent/US20090104231A1/en not_active Abandoned
-
2009
- 2009-05-26 US US12/471,772 patent/US20090232847A1/en not_active Abandoned
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