JP2004531242A5 - - Google Patents
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- Publication number
- JP2004531242A5 JP2004531242A5 JP2002571881A JP2002571881A JP2004531242A5 JP 2004531242 A5 JP2004531242 A5 JP 2004531242A5 JP 2002571881 A JP2002571881 A JP 2002571881A JP 2002571881 A JP2002571881 A JP 2002571881A JP 2004531242 A5 JP2004531242 A5 JP 2004531242A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- host cell
- seq
- amino acids
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 208000004296 neuralgia Diseases 0.000 claims 2
- 208000021722 neuropathic pain Diseases 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/804,615 US20020055467A1 (en) | 1998-07-06 | 2001-03-12 | Novel neurotrophic factors |
| PCT/EP2002/002691 WO2002072826A2 (en) | 2001-03-12 | 2002-03-12 | Neurotrophic factors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005027109A Division JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004531242A JP2004531242A (ja) | 2004-10-14 |
| JP2004531242A5 true JP2004531242A5 (enExample) | 2005-06-23 |
| JP3738008B2 JP3738008B2 (ja) | 2006-01-25 |
Family
ID=25189406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002571881A Expired - Fee Related JP3738008B2 (ja) | 2001-03-12 | 2002-03-12 | 神経栄養因子 |
| JP2005027109A Withdrawn JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005027109A Withdrawn JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20020055467A1 (enExample) |
| EP (2) | EP1930439B1 (enExample) |
| JP (2) | JP3738008B2 (enExample) |
| CN (1) | CN1268744C (enExample) |
| AT (2) | ATE378353T1 (enExample) |
| AU (1) | AU2002240943B2 (enExample) |
| CA (1) | CA2440767C (enExample) |
| CY (1) | CY1111750T1 (enExample) |
| DE (1) | DE60223511T2 (enExample) |
| DK (2) | DK1373503T3 (enExample) |
| ES (2) | ES2296899T3 (enExample) |
| NZ (1) | NZ528790A (enExample) |
| PT (2) | PT1373503E (enExample) |
| SI (2) | SI1930439T1 (enExample) |
| WO (1) | WO2002072826A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| WO2000004050A2 (en) * | 1998-07-14 | 2000-01-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
| MXPA03005721A (es) * | 2000-12-22 | 2004-04-21 | Genentech Inc | Uso novedoso de artemina, un miembro de la familia de ligandos gdnf. |
| US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| CA2442159C (en) * | 2001-03-28 | 2011-08-23 | Biogen, Inc. | Treatment using neublastin polypeptides |
| JP2005516949A (ja) * | 2001-12-19 | 2005-06-09 | リジュン・ワン | Ｇｄｎｆの骨格筋へのアデノ随伴ウイルス媒介性のデリバリー |
| JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Ｊｘ日鉱日石エネルギー株式会社 | 潤滑油組成物 |
| EP2301960A3 (en) * | 2003-01-31 | 2011-08-03 | Biogen Idec MA Inc. | Polymer conjugates of mutated neublastin |
| NZ543365A (en) | 2003-04-18 | 2009-02-28 | Biogen Idec Inc | Polymer-conjugated glycosylated neublastin |
| DE602004019524D1 (de) | 2003-06-10 | 2009-04-02 | Nsgene As | Verbesserte sezernierung von neublastin |
| US7598059B2 (en) * | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| WO2005039643A2 (en) | 2003-10-20 | 2005-05-06 | Nsgene A/S | In vivo gene therapy of parkinson's disease |
| DE602005022082D1 (de) * | 2004-08-19 | 2010-08-12 | Biogen Idec Inc | Rückfaltung von proteinen der transforming-growth-factor-beta-familie |
| EP1786454B1 (en) * | 2004-08-19 | 2010-07-21 | Biogen Idec MA Inc. | Neublastin variants |
| EP1937295A2 (en) * | 2005-10-11 | 2008-07-02 | NS Gene A/S | Treatment of retinopathies using gfr 3 agonists |
| TWI501774B (zh) * | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| ES2450065T3 (es) * | 2006-03-01 | 2014-03-21 | Biogen Idec Ma Inc. | Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF |
| US8329655B2 (en) | 2007-05-01 | 2012-12-11 | Biogen Idec Ma Inc. | Methods for increasing vascularization |
| US20110135648A1 (en) * | 2007-08-08 | 2011-06-09 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
| US20100247437A1 (en) * | 2007-10-01 | 2010-09-30 | Vgx Pharmaceuticals, Llc | Materials and methods for the delivery of biomolecules to cells of an organ |
| CA2813013C (en) * | 2010-10-01 | 2019-10-22 | Nsgene A/S | Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain |
| JP7235230B2 (ja) * | 2018-05-17 | 2023-03-08 | ヘリックスミス カンパニー， リミテッド | 化学療法－誘発末梢神経病症と関連した神経病症性痛みの治療 |
| CN117279657A (zh) | 2021-05-18 | 2023-12-22 | 日本株式会社Ltt生物医药 | 用于治疗或预防伴随抗癌剂给药的障碍的医药组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
| KR100587556B1 (ko) | 1996-05-08 | 2006-06-08 | 바이오겐 아이덱 엠에이 인코포레이티드 | 신경 및 신장 증식을 자극하기 위한 ＲＥＴ리간드（ＲｅｔＬ) |
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| JP2002531128A (ja) * | 1998-12-09 | 2002-09-24 | アムジエン・インコーポレーテツド | 神経栄養因子ｇｒｎｆ４ |
| PT1185648E (pt) * | 1999-06-22 | 2007-06-29 | Genentech Inc | Métodos e composições para a inibição do crescimento de células neoplásicas. |
-
2001
- 2001-03-12 US US09/804,615 patent/US20020055467A1/en not_active Abandoned
-
2002
- 2002-03-12 SI SI200230954T patent/SI1930439T1/sl unknown
- 2002-03-12 AT AT02706759T patent/ATE378353T1/de active
- 2002-03-12 CA CA2440767A patent/CA2440767C/en not_active Expired - Fee Related
- 2002-03-12 EP EP07120461A patent/EP1930439B1/en not_active Expired - Lifetime
- 2002-03-12 NZ NZ528790A patent/NZ528790A/en not_active IP Right Cessation
- 2002-03-12 AU AU2002240943A patent/AU2002240943B2/en not_active Ceased
- 2002-03-12 WO PCT/EP2002/002691 patent/WO2002072826A2/en not_active Ceased
- 2002-03-12 EP EP02706759A patent/EP1373503B1/en not_active Expired - Lifetime
- 2002-03-12 JP JP2002571881A patent/JP3738008B2/ja not_active Expired - Fee Related
- 2002-03-12 PT PT02706759T patent/PT1373503E/pt unknown
- 2002-03-12 SI SI200230656T patent/SI1373503T1/sl unknown
- 2002-03-12 DK DK02706759T patent/DK1373503T3/da active
- 2002-03-12 PT PT07120461T patent/PT1930439E/pt unknown
- 2002-03-12 DE DE60223511T patent/DE60223511T2/de not_active Expired - Lifetime
- 2002-03-12 AT AT07120461T patent/ATE509103T1/de active
- 2002-03-12 ES ES02706759T patent/ES2296899T3/es not_active Expired - Lifetime
- 2002-03-12 DK DK07120461.4T patent/DK1930439T3/da active
- 2002-03-12 ES ES07120461T patent/ES2366610T3/es not_active Expired - Lifetime
- 2002-03-12 CN CNB028097858A patent/CN1268744C/zh not_active Expired - Fee Related
-
2005
- 2005-02-02 JP JP2005027109A patent/JP2005198656A/ja not_active Withdrawn
-
2011
- 2011-08-10 CY CY20111100765T patent/CY1111750T1/el unknown