|
US8563522B2
(en)
|
1997-07-08 |
2013-10-22 |
The Iams Company |
Method of maintaining and/or attenuating a decline in quality of life
|
|
US7381413B1
(en)
*
|
1998-04-17 |
2008-06-03 |
University Of Vermont And State Agricultural College |
Methods and products related to metabolic interactions in disease
|
|
EP1205493A1
(en)
*
|
2000-11-14 |
2002-05-15 |
ATOFINA Research |
Polymerisation catalyst systems and their preparation
|
|
US7666459B2
(en)
*
|
2001-09-12 |
2010-02-23 |
The Procter & Gamble Company |
Pet food compositions
|
|
US7547673B2
(en)
*
|
2001-09-13 |
2009-06-16 |
The Johns Hopkins University |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
|
|
US20060276527A1
(en)
*
|
2003-01-17 |
2006-12-07 |
Thresold Pharmaceuticals, Inc. |
Combination therapies for the treatment of cancer
|
|
US20050158294A1
(en)
|
2003-12-19 |
2005-07-21 |
The Procter & Gamble Company |
Canine probiotic Bifidobacteria pseudolongum
|
|
US8877178B2
(en)
|
2003-12-19 |
2014-11-04 |
The Iams Company |
Methods of use of probiotic bifidobacteria for companion animals
|
|
WO2005070126A2
(en)
*
|
2004-01-08 |
2005-08-04 |
The Regents Of The University Of Colorado |
Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
|
|
WO2005076888A2
(en)
*
|
2004-02-06 |
2005-08-25 |
Threshold Pharmaceuticals, Inc. |
Anti-cancer therapies
|
|
US20090252834A1
(en)
*
|
2004-05-10 |
2009-10-08 |
Michael Griffin Hayek |
Compositions comprising glucose anti-metabolites
|
|
WO2006002121A2
(en)
|
2004-06-17 |
2006-01-05 |
Wisconsin Alumni Research Foundation |
Compounds and methods for treating seizure and paroxysmal disorders
|
|
EP1789107B1
(en)
*
|
2004-08-30 |
2009-05-27 |
Interstitial Therapeutics |
Medical stent provided with inhibitors of atp synthesis
|
|
US20060078580A1
(en)
*
|
2004-10-08 |
2006-04-13 |
Mediquest Therapeutics, Inc. |
Organo-gel formulations for therapeutic applications
|
|
US7740875B2
(en)
*
|
2004-10-08 |
2010-06-22 |
Mediquest Therapeutics, Inc. |
Organo-gel formulations for therapeutic applications
|
|
EP1814392A4
(en)
*
|
2004-11-02 |
2008-06-11 |
Conforma Therapeutics Corp |
METHODS AND COMPOSITIONS FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA
|
|
HUE038768T2
(hu)
|
2005-02-18 |
2018-11-28 |
Abraxis Bioscience Llc |
Terápiás szerek kombinációi, valamint beadásukra szolgáló módszerek, és kombinációs terápia
|
|
US8735394B2
(en)
|
2005-02-18 |
2014-05-27 |
Abraxis Bioscience, Llc |
Combinations and modes of administration of therapeutic agents and combination therapy
|
|
US7208611B2
(en)
|
2005-02-23 |
2007-04-24 |
Xenoport, Inc. |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
|
|
WO2006108682A2
(en)
|
2005-04-15 |
2006-10-19 |
Biomac Privatinstitut Für Medizinische Und Zahnmedizinische Forschung, Entwicklung Und Diagnostik Gmbh |
Substances and pharmaceutical compositions for the inhibition of glyoxalases and their use as anti-fungal agents
|
|
WO2006130187A1
(en)
|
2005-05-31 |
2006-12-07 |
The Iams Company |
Feline probiotic lactobacilli
|
|
EP1885383B1
(en)
|
2005-05-31 |
2016-09-21 |
IAMS Europe B.V. |
Feline probiotic bifidobacteria
|
|
US20060287253A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Kriegler Steven M |
Compounds and methods for treating seizure disorders
|
|
JPWO2006137595A1
(ja)
*
|
2005-06-24 |
2009-01-22 |
武田薬品工業株式会社 |
Ｈｅｒ２発現癌の予防・治療薬
|
|
US20070032383A1
(en)
*
|
2005-07-27 |
2007-02-08 |
Newell M K |
Systems, methods, and compositions for modifying the metabolism of plants and of euucaryotic microbes
|
|
US20070134349A1
(en)
*
|
2005-09-19 |
2007-06-14 |
Duke University |
Methods of treating hematological malignancies
|
|
WO2007064448A2
(en)
*
|
2005-11-28 |
2007-06-07 |
Ramot At Tel Aviv University, Ltd. |
Cancer treatment using fts and 2-deoxyglucose
|
|
WO2007067516A2
(en)
*
|
2005-12-06 |
2007-06-14 |
Duke University |
Multiple myeloma
|
|
US7754693B2
(en)
*
|
2006-02-16 |
2010-07-13 |
Young Hee Ko |
Composition and method for the efficacious and safe administration of halopyruvate for the treatment of cancer
|
|
US8324175B2
(en)
*
|
2006-02-16 |
2012-12-04 |
Young Hee Ko |
Compositions and methods for the treatment of cancer
|
|
KR20080096807A
(ko)
*
|
2006-02-24 |
2008-11-03 |
보오드 오브 리젠츠, 더 유니버시티 오브 텍사스 시스템 |
암 치료용 6탄당 화합물
|
|
US8242167B2
(en)
*
|
2006-02-24 |
2012-08-14 |
University Of Miami |
Mannose derivatives for killing tumor cells
|
|
US9149489B2
(en)
*
|
2006-04-27 |
2015-10-06 |
Board Of Regents, University Of Texas System |
Inhibitors of glycolysis useful in the treatment of brain tumors
|
|
WO2009108926A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Board Of Regents, The University Of Texas System |
Inhibitors of glycolysis useful in the treatment of brain tumors
|
|
RU2398578C2
(ru)
*
|
2006-05-03 |
2010-09-10 |
И.К.А., А.С. |
Фармацевтическая композиция, содержащая производное таксана, которая предназначена для приготовления инфузионного раствора, способ его приготовления и использование
|
|
US8389248B2
(en)
|
2006-11-20 |
2013-03-05 |
National University Corporation Kagawa University |
Deoxyketohexose isomerase and method for producing deoxyhexose and derivative thereof using same
|
|
WO2008076964A1
(en)
*
|
2006-12-18 |
2008-06-26 |
The Johns Hopkins University |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of atp production
|
|
MX2009008166A
(es)
|
2007-02-01 |
2009-08-12 |
Iams Company |
Metodo para disminuir la inflamacion y estres en un mamifero usando antimetabolitos de glucosa, aguacate o extractos de aguacate.
|
|
US8865646B2
(en)
*
|
2007-03-28 |
2014-10-21 |
University Of South California |
Dietary compositions and methods for protection against chemotherapy, radiotherapy, oxidative stress, and aging
|
|
ES2891733T3
(es)
*
|
2007-03-28 |
2022-01-31 |
Univ Southern California |
Inducción de la resistencia diferencial al estrés y usos de la misma
|
|
RU2349271C2
(ru)
*
|
2007-03-29 |
2009-03-20 |
ФГУ Ростовский научно-исследовательский онкологический институт Росздрава |
Способ лечения рака прямой кишки
|
|
US8642067B2
(en)
|
2007-04-02 |
2014-02-04 |
Allergen, Inc. |
Methods and compositions for intraocular administration to treat ocular conditions
|
|
WO2008124691A1
(en)
*
|
2007-04-05 |
2008-10-16 |
Threshold Pharmaceuticals, Inc. |
Glufosfamide combination therapy
|
|
WO2009102986A1
(en)
*
|
2008-02-15 |
2009-08-20 |
Catholic Healthcare West (D/B/A St. Joseph's Hospital And Medical Center) |
Treatment of adenocarcinoma expressing lkb1 with mtor inhibitor in combination with cox1 inhibitor
|
|
WO2009105230A2
(en)
|
2008-02-21 |
2009-08-27 |
The Regents Of The University Of Colorado |
Methods for treating cancer using combination therapy
|
|
CA2723197C
(en)
|
2008-05-02 |
2017-09-19 |
Seattle Genetics, Inc. |
Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
|
|
US20110183926A1
(en)
*
|
2008-05-23 |
2011-07-28 |
University Of Miami |
Treatment using continuous low dose application of sugar analogs
|
|
CN102065873A
(zh)
*
|
2008-05-27 |
2011-05-18 |
昂科利蒂克斯生物科技公司 |
在溶瘤呼肠孤病毒治疗中消除促炎细胞因子的产生
|
|
US9771199B2
(en)
|
2008-07-07 |
2017-09-26 |
Mars, Incorporated |
Probiotic supplement, process for making, and packaging
|
|
DK2310020T3
(en)
*
|
2008-07-11 |
2017-06-26 |
Univ Texas |
PRESENT UNKNOWN ACETATES OF 2-DEOXY MONOSACCHARIDES WITH ANTICANCER ACTIVITY
|
|
CA2730773A1
(en)
*
|
2008-07-14 |
2010-01-21 |
Martha Karen Newell |
Methods and products for treating proliferative diseases
|
|
US20110207680A1
(en)
*
|
2008-08-13 |
2011-08-25 |
Curd John G |
Administration of Glufosfamide For The Treatment of Cancer
|
|
WO2010021750A2
(en)
*
|
2008-08-21 |
2010-02-25 |
The Johns Hopkins University |
Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
|
|
UA104147C2
(uk)
*
|
2008-09-10 |
2014-01-10 |
Новартис Аг |
Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
|
|
WO2010088564A2
(en)
*
|
2009-01-29 |
2010-08-05 |
Young Hee Ko |
Compositions and methods for the treatment of cancer
|
|
MX346801B
(es)
|
2009-03-13 |
2017-03-31 |
Agios Pharmaceuticals Inc |
Métodos y composiciones para trastornos relacionados con la proliferación celular.
|
|
SG177434A1
(en)
|
2009-06-29 |
2012-02-28 |
Agios Pharmaceuticals Inc |
Therapeutic compounds and compositions
|
|
US10104903B2
(en)
|
2009-07-31 |
2018-10-23 |
Mars, Incorporated |
Animal food and its appearance
|
|
US8450090B2
(en)
|
2009-10-06 |
2013-05-28 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods for promoting fatty acid production in plants
|
|
WO2011050210A1
(en)
|
2009-10-21 |
2011-04-28 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
CA2793836C
(en)
|
2009-10-21 |
2020-03-24 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
PE20121709A1
(es)
|
2009-10-22 |
2012-12-17 |
Propanc Pty Ltd |
Una composicion farmaceutica para tratar cancer que comprende tripsinogeno y/o quimotripsinogeno y un agente activo seleccionado a partir de un compuesto de selenio, un compuesto vainilloide y un agente reductor de glicolisis citoplasmica
|
|
CN102115483B
(zh)
*
|
2009-12-30 |
2014-12-17 |
苏州天人合生物技术有限公司 |
卤代双去氧糖衍生物及其制备方法与应用
|
|
GB2478556A
(en)
*
|
2010-03-09 |
2011-09-14 |
Myrovlytis Technology Ventures Ltd |
A composition for use in the treatment of Birt-Hogg-Dubô sydrome
|
|
US9393318B2
(en)
|
2010-03-29 |
2016-07-19 |
Abraxis Bioscience, Llc |
Methods of treating cancer
|
|
BR112012024590A2
(pt)
|
2010-03-29 |
2016-05-31 |
Abraxis Bioscience Inc |
métodos de reforço da liberação de fármaco e da eficácia de agentes terapêuticos
|
|
KR20130088116A
(ko)
|
2010-06-04 |
2013-08-07 |
아브락시스 바이오사이언스, 엘엘씨 |
췌장암의 치료 방법
|
|
DK2608796T3
(en)
|
2010-08-05 |
2019-03-18 |
Seattle Genetics Inc |
Inhibition of protein fucosylation in vivo using fucose analogues
|
|
CN112755029A
(zh)
|
2010-10-13 |
2021-05-07 |
穆斯塔法·比尔金·阿里·贾姆戈兹 |
治疗癌症/抑制转移
|
|
WO2012049439A1
(en)
*
|
2010-10-13 |
2012-04-19 |
Imperial Innovations Limited |
Treatment of cancer/inhibition of metastasis
|
|
US20120276108A1
(en)
*
|
2011-01-11 |
2012-11-01 |
Intertech Bio |
Monosaccharide-based compounds for the treatment of proliferative and inflammatory dermatological diseases
|
|
WO2012123774A1
(en)
*
|
2011-03-11 |
2012-09-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Glycolytic inhibitor with cytotoxic agent for use in the treatment of a cancer
|
|
US20120238511A1
(en)
*
|
2011-03-14 |
2012-09-20 |
University Of Southern California |
2-deoxy-d-glucose formulations for prevention or treatment of neurodegenerative diseases
|
|
PT2704721T
(pt)
|
2011-05-03 |
2018-06-14 |
Agios Pharmaceuticals Inc |
Ativadores da piruvato-cinase para utilização em terapia
|
|
CN102827073A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
CN102827170A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
WO2013017282A1
(en)
*
|
2011-08-02 |
2013-02-07 |
Roche Diagnostics Gmbh |
In vitro tumor metastasis model
|
|
KR101900478B1
(ko)
*
|
2011-08-04 |
2018-09-20 |
한올바이오파마주식회사 |
암의 재발 또는 전이의 억제용 약제학적 조성물
|
|
UA117451C2
(uk)
|
2012-01-06 |
2018-08-10 |
Аджиос Фармасьютікалз, Інк. |
Терапевтично активні сполуки і способи їх застосування
|
|
US9474779B2
(en)
|
2012-01-19 |
2016-10-25 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compositions and their methods of use
|
|
WO2013123151A1
(en)
*
|
2012-02-14 |
2013-08-22 |
The Wistar Institute Of Anatomy And Biology |
Methods of controlling tumor bioenergetics networks
|
|
AU2013202693B2
(en)
*
|
2012-04-16 |
2015-01-22 |
Baxalta GmbH |
Combination Therapy of Anti-MIF Antibodies and Chemotherapeutics
|
|
US10350228B2
(en)
|
2012-08-23 |
2019-07-16 |
Seattle Genetics, Inc. |
Treatment of sickle cell disease and inflammatory conditions
|
|
WO2014062511A1
(en)
|
2012-10-15 |
2014-04-24 |
Agios Pharmaceuticals, Inc. |
Therapeutic compounds and compositions
|
|
WO2014072967A1
(en)
*
|
2012-11-12 |
2014-05-15 |
Urifer Ltd |
Drug combination comprising a glycolysis inhibitor and a tyrosine kinase inhibitor
|
|
KR101419816B1
(ko)
*
|
2013-01-30 |
2014-07-17 |
(주)제욱 |
상승적 치료 효과를 갖는 비소세포폐암의 예방 또는 치료용 조성물
|
|
EP2981270B1
(en)
|
2013-04-05 |
2021-08-25 |
Board of Regents, The University of Texas System |
Esters of 2-deoxy-monosaccharides with anti proliferative activity
|
|
WO2015006591A1
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
2,4- or 4,6-diaminopyrimidine compounds as idh2 mutants inhibitors for the treatment of cancer
|
|
WO2015003355A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
US9579324B2
(en)
|
2013-07-11 |
2017-02-28 |
Agios Pharmaceuticals, Inc |
Therapeutically active compounds and their methods of use
|
|
WO2015003360A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
US20150031627A1
(en)
|
2013-07-25 |
2015-01-29 |
Agios Pharmaceuticals, Inc |
Therapeutically active compounds and their methods of use
|
|
JP6552509B2
(ja)
|
2014-01-14 |
2019-07-31 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
選択的ａｔｐ阻害剤をカプセル化するシクロデキストリン組成物およびその使用
|
|
UA121211C2
(uk)
|
2014-03-14 |
2020-04-27 |
Аджіос Фармасьютикалз, Інк. |
Фармацевтична композиція, що містить тверду дисперсію, та спосіб лікування гострої мієлогенної/мієлоїдної лейкемії (гмл)
|
|
WO2016065353A1
(en)
*
|
2014-10-24 |
2016-04-28 |
University Of Miami |
Combination therapy with fenofibrate and 2-deoxyglucose or 2-deoxymannose
|
|
SI3307271T1
(sl)
|
2015-06-11 |
2023-11-30 |
Agios Pharmaceuticals, Inc. |
Postopki za uporabo aktivatorjev piruvat kinaze
|
|
MD3362065T2
(ro)
|
2015-10-15 |
2024-08-31 |
Servier Lab |
Terapie combinată care conține ivosidenib, citarabină și daunorubicina sau idarubicina pentru tratarea leucemiei acute mielogene
|
|
DK3362066T3
(da)
|
2015-10-15 |
2021-11-22 |
Les Laboratoires Servier Sas |
Kombinationsterapi til behandling af maligniteter
|
|
US10751306B2
(en)
|
2015-11-06 |
2020-08-25 |
The Johns Hopkins University |
Methods of treating liver fibrosis by administering 3-bromopyruvate
|
|
US12419938B2
(en)
|
2015-11-12 |
2025-09-23 |
Propanc Pty Ltd |
Proenzyme composition
|
|
IL260814B2
(en)
|
2016-01-29 |
2023-04-01 |
Propanc Pty Ltd |
Cancer treatment
|
|
WO2017173360A2
(en)
*
|
2016-03-31 |
2017-10-05 |
Stcube, Inc. |
Combination treatments directed toward programmed death ligand-1 (pd-l1) positive cancers
|
|
CN110831603A
(zh)
|
2017-06-28 |
2020-02-21 |
株式会社先端医疗开发 |
药物组合物以及肿瘤免疫活性促进剂
|
|
US11773051B2
(en)
|
2017-07-21 |
2023-10-03 |
Buck Institute For Research On Aging |
S-enantiomers of beta-hydroxybutyrate and butanediol and methods for using same
|
|
US12037317B2
(en)
|
2018-01-25 |
2024-07-16 |
Buck Institute For Research On Aging |
Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
|
|
US11311527B2
(en)
|
2018-05-16 |
2022-04-26 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)
|
|
WO2019222551A1
(en)
|
2018-05-16 |
2019-11-21 |
Forma Therapeutics, Inc. |
Solid forms of ((s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile
|
|
US11013734B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation
|
|
US11013733B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1)
|
|
PT3720442T
(pt)
|
2018-05-16 |
2023-03-13 |
Forma Therapeutics Inc |
Inibição de idh-1 mutante
|
|
US10980788B2
(en)
|
2018-06-08 |
2021-04-20 |
Agios Pharmaceuticals, Inc. |
Therapy for treating malignancies
|
|
RU2707554C1
(ru)
*
|
2019-02-27 |
2019-11-28 |
Федеральное государственное бюджетное учреждение "Петербургский институт ядерной физики им. Б.П. Константинова Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт-ПИЯФ") |
Композиция, ингибирующая рост и выживаемость опухолевых клеток
|
|
JP2023518249A
(ja)
|
2020-03-16 |
2023-04-28 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
ヘキソース型単糖およびその類縁体による、ウイルス感染症の処置方法
|
|
WO2021211609A1
(en)
*
|
2020-04-16 |
2021-10-21 |
Buck Institute For Research On Aging |
Treatment of viral pathologies with exogenous ketones
|
|
AU2021399800A1
(en)
*
|
2020-12-14 |
2023-07-20 |
Trim Biotech, S.L. |
Compositions comprising bacteria for cancer immunotherapy
|
|
WO2023062516A1
(en)
*
|
2021-10-11 |
2023-04-20 |
Exploration Invest Pte Ltd |
2-deoxy-d-glucose for use in disease therapy
|
|
CN114617876B
(zh)
*
|
2022-01-28 |
2023-04-07 |
四川大学华西医院 |
一种抗肿瘤联合用药物
|
|
KR20240038394A
(ko)
|
2022-09-16 |
2024-03-25 |
이화여자대학교 산학협력단 |
해당과정 억제제 및 미토콘드리아 기능 억제제를 포함하는 암의 예방 또는 치료용 약학적 조성물
|
|
EP4582080A1
(en)
|
2024-01-02 |
2025-07-09 |
G.ST Antivirals GmbH |
Dispenser for mucosal administration comprising 2-deoxy-glucose or analogues thereof
|