JP2006515595A5 - - Google Patents
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- Publication number
- JP2006515595A5 JP2006515595A5 JP2004564206A JP2004564206A JP2006515595A5 JP 2006515595 A5 JP2006515595 A5 JP 2006515595A5 JP 2004564206 A JP2004564206 A JP 2004564206A JP 2004564206 A JP2004564206 A JP 2004564206A JP 2006515595 A5 JP2006515595 A5 JP 2006515595A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsubstituted
- halogen
- substituted
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10300017A DE10300017A1 (de) | 2003-01-03 | 2003-01-03 | Selektive MMP 13 Inhibitoren |
| PCT/EP2003/014612 WO2004060883A1 (de) | 2003-01-03 | 2003-12-19 | Pyrimidin-4,6-dicarbonsäurediamide als selektive mmp 13 inhibitoren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006515595A JP2006515595A (ja) | 2006-06-01 |
| JP2006515595A5 true JP2006515595A5 (enExample) | 2007-01-25 |
Family
ID=32519591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004564206A Abandoned JP2006515595A (ja) | 2003-01-03 | 2003-12-19 | 選択的ｍｍｐ１３阻害剤として使用するピリミジン−４，６−ジカルボン酸ジアミド |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1587803A1 (enExample) |
| JP (1) | JP2006515595A (enExample) |
| AR (1) | AR042687A1 (enExample) |
| AU (1) | AU2003293951A1 (enExample) |
| BR (1) | BR0317834A (enExample) |
| CA (1) | CA2512183A1 (enExample) |
| DE (1) | DE10300017A1 (enExample) |
| MX (1) | MXPA05006401A (enExample) |
| PE (1) | PE20040916A1 (enExample) |
| TW (1) | TW200505906A (enExample) |
| WO (1) | WO2004060883A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060173183A1 (en) * | 2004-12-31 | 2006-08-03 | Alantos Pharmaceuticals, Inc., | Multicyclic bis-amide MMP inhibitors |
| US20070155737A1 (en) * | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
| US20070155738A1 (en) * | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
| WO2007079199A2 (en) * | 2005-12-30 | 2007-07-12 | Alantos Pharmaceuticals, Holding, Inc. | Substituted bis-amide metalloprotease inhibitors |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| AU2007321922A1 (en) * | 2006-11-20 | 2008-05-29 | Alantos Pharmaceuticals Holding, Inc. | Heterobicyclic matrix metalloprotease inhibitors |
| US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
| CN105130948A (zh) | 2010-04-22 | 2015-12-09 | 弗特克斯药品有限公司 | 制备环烷基甲酰胺基-吲哚化合物的方法 |
| JP6543268B2 (ja) | 2014-04-15 | 2019-07-10 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 嚢胞性線維症膜コンダクタンス調節因子が媒介する疾患を処置するための医薬組成物 |
| GB201908453D0 (en) * | 2019-06-12 | 2019-07-24 | Enterprise Therapeutics Ltd | Compounds for treating respiratory disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3931432A1 (de) * | 1989-09-21 | 1991-04-04 | Hoechst Ag | Pyrimidin-4,6-dicarbonsaeurediamide, verfahren zu deren herstellung sowie verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| JP2004518723A (ja) * | 2001-02-14 | 2004-06-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | ピリミジンマトリックスメタロプロテイナーゼ阻害剤 |
| DE10160357A1 (de) * | 2001-12-08 | 2003-06-18 | Aventis Pharma Gmbh | Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen |
-
2003
- 2003-01-03 DE DE10300017A patent/DE10300017A1/de not_active Withdrawn
- 2003-12-12 PE PE2003001280A patent/PE20040916A1/es not_active Application Discontinuation
- 2003-12-19 BR BR0317834-0A patent/BR0317834A/pt not_active IP Right Cessation
- 2003-12-19 EP EP03789359A patent/EP1587803A1/de not_active Withdrawn
- 2003-12-19 WO PCT/EP2003/014612 patent/WO2004060883A1/de not_active Ceased
- 2003-12-19 CA CA002512183A patent/CA2512183A1/en not_active Abandoned
- 2003-12-19 JP JP2004564206A patent/JP2006515595A/ja not_active Abandoned
- 2003-12-19 MX MXPA05006401A patent/MXPA05006401A/es unknown
- 2003-12-19 AU AU2003293951A patent/AU2003293951A1/en not_active Abandoned
- 2003-12-30 AR ARP030104874A patent/AR042687A1/es unknown
- 2003-12-31 TW TW092137550A patent/TW200505906A/zh unknown
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