JP2006514636A5 - - Google Patents
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- Publication number
- JP2006514636A5 JP2006514636A5 JP2004557434A JP2004557434A JP2006514636A5 JP 2006514636 A5 JP2006514636 A5 JP 2006514636A5 JP 2004557434 A JP2004557434 A JP 2004557434A JP 2004557434 A JP2004557434 A JP 2004557434A JP 2006514636 A5 JP2006514636 A5 JP 2006514636A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- wta
- infection
- antibody
- staphylococcal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 20
- 239000012634 fragment Substances 0.000 claims 9
- 208000015181 infectious disease Diseases 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 206010041925 Staphylococcal infections Diseases 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 208000034309 Bacterial disease carrier Diseases 0.000 claims 4
- 238000011109 contamination Methods 0.000 claims 3
- 230000009885 systemic effect Effects 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- 241000295644 Staphylococcaceae Species 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 230000000941 anti-staphylcoccal effect Effects 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- VJDOAZKNBQCAGE-LMVFSUKVSA-N D-ribitol 5-phosphate Chemical compound OC[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O VJDOAZKNBQCAGE-LMVFSUKVSA-N 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 108090000988 Lysostaphin Proteins 0.000 claims 1
- 108010053775 Nisin Proteins 0.000 claims 1
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000004309 nisin Substances 0.000 claims 1
- 235000010297 nisin Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43022502P | 2002-12-02 | 2002-12-02 | |
| PCT/US2003/038132 WO2004050846A2 (en) | 2002-12-02 | 2003-12-01 | Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514636A JP2006514636A (ja) | 2006-05-11 |
| JP2006514636A5 true JP2006514636A5 (enExample) | 2007-06-07 |
Family
ID=32469426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004557434A Pending JP2006514636A (ja) | 2002-12-02 | 2003-12-01 | 抗ブドウ球菌療法およびワクチンの標的としての壁テイコイン酸 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040247605A1 (enExample) |
| EP (1) | EP1567868A4 (enExample) |
| JP (1) | JP2006514636A (enExample) |
| AU (2) | AU2003298770A1 (enExample) |
| CA (1) | CA2507711A1 (enExample) |
| WO (1) | WO2004050846A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
| US6824997B1 (en) * | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
| US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| US8394379B2 (en) | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| WO2007024852A2 (en) * | 2005-08-22 | 2007-03-01 | Biosynexus Incorporated | Methods for testing vaccine candidates against bacterial infection in rodents |
| WO2007047189A2 (en) * | 2005-10-11 | 2007-04-26 | Iogenetics, Llc | Targeted biocides |
| KR20100072228A (ko) * | 2007-08-31 | 2010-06-30 | 유니버시티 오브 시카고 | 스타필로코커스 폐 질환 및 상태에 대한 면역화와 관련된 방법 및 조성물 |
| WO2009114520A2 (en) * | 2008-03-10 | 2009-09-17 | Pharmain Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
| WO2009151561A2 (en) * | 2008-06-12 | 2009-12-17 | President And Fellows Of Harvard College | Methods and compounds for antimicrobial intervention |
| KR20110124060A (ko) * | 2010-05-10 | 2011-11-16 | 부산대학교 산학협력단 | Wta를 유효성분으로 함유하는 백신 조성물 |
| CA2856085C (en) | 2011-11-18 | 2020-06-30 | National Research Council Of Canada | Clostridium difficile lipoteichoic acid and uses thereof |
| CN103383354B (zh) * | 2012-05-03 | 2016-11-09 | 北京博迈世纪生物技术有限公司 | 一种检测肠毒素sea的磁微粒化学发光试剂盒的检测方法 |
| US20150147328A1 (en) * | 2012-05-07 | 2015-05-28 | Mogam Biotechnology Institute | Vaccine composition for preventing staphyllococcus aureus infection |
| BR112015029754A2 (pt) | 2013-05-31 | 2017-09-26 | Genentech Inc | anticorpos anti-teicoico da parede e conjugados |
| BR112015029838A2 (pt) * | 2013-05-31 | 2017-09-26 | Genentech Inc | anticorpos, composições, ácido nucleico isolado, vetor, célula hospedeira isolada, método de produção de anticorpos, composto, conjugado de anticorpo e antibiótico, processo de elaboração do composto, intermediário entre ligante e antibiótico, método de tratamento de infecções bacterianas e método de matar staphylococcus aureus |
| US9803002B2 (en) | 2013-05-31 | 2017-10-31 | Genentench, Inc. | Anti-wall teichoic antibodies and conjugates |
| US20140356375A1 (en) * | 2013-05-31 | 2014-12-04 | Genentech, Inc. | Anti-wall teichoic antibodies and conjugates |
| EP3150217A1 (en) * | 2014-05-29 | 2017-04-05 | Green Cross Corporation | Composition for preventing or treating staphylococcus aureus infection |
| CN107206102A (zh) * | 2014-12-03 | 2017-09-26 | 豪夫迈·罗氏有限公司 | 抗金黄色葡萄球菌抗体利福霉素缀合物及其用途 |
| WO2017010845A1 (ko) * | 2015-07-15 | 2017-01-19 | 재단법인 목암생명과학연구소 | 포도상구균 감염 질환의 예방 또는 치료용 조성물 |
| WO2017198731A1 (en) * | 2016-05-18 | 2017-11-23 | Genmab B.V. | Antibodies and methods of use thereof in treatment of infectious disease |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250262A (en) * | 1979-12-14 | 1981-02-10 | Forsyth Dental Infirmary For Children | Method of preparing a purified glucosyltransferase |
| US5139933A (en) * | 1989-09-26 | 1992-08-18 | Vicam, L.P. | Assay method for detecting listeria |
| US5571511A (en) * | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| US5290707A (en) * | 1991-11-25 | 1994-03-01 | The United States Of America As Represented By The Secretary Of The Army | Method for detection of microorganisms |
| US5367058A (en) * | 1993-08-25 | 1994-11-22 | Becton, Dickinson And Company | Modified antibodies with increased affinity |
| US5904925A (en) * | 1993-12-09 | 1999-05-18 | Exner; Heinrich | Adjuvant for antigens, and process for making |
| US6350597B1 (en) * | 1994-01-13 | 2002-02-26 | E. I. Du Pont De Nemours & Company | Riboflavin synthase genes and enzymes and methods of use |
| US6203997B1 (en) * | 1994-06-08 | 2001-03-20 | Sepsis, Inc. | Quantitation of analytes in whole blood |
| ATE219146T1 (de) * | 1995-01-30 | 2002-06-15 | Lunamed Ag | Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten |
| WO1997013845A2 (en) * | 1995-10-13 | 1997-04-17 | President And Fellows Of Harvard College | Phosphopantetheinyl transferases and uses thereof |
| US5770208A (en) * | 1996-09-11 | 1998-06-23 | Nabi | Staphylococcus aureus B-linked hexosamine antigen |
| US6610293B1 (en) * | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| US5889171A (en) * | 1997-07-18 | 1999-03-30 | Smithkline Beecham Corporation | TarF |
| JP2001510805A (ja) * | 1997-07-23 | 2001-08-07 | アンビィー インコーポレイテッド | リソスタフィン単独含有もしくは抗生物質併用ブドウ球菌感染症治療用薬剤組成物 |
| US7250494B2 (en) * | 1998-06-15 | 2007-07-31 | Biosynexus Incorporated | Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria |
| US7252828B2 (en) * | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6585973B1 (en) * | 1998-10-29 | 2003-07-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for preparing solid phase conjugated vaccine |
| SI1141308T1 (sl) * | 1998-12-22 | 2007-08-31 | Microscience Ltd | Streptokokni proteini skupine B in njihova uporaba |
| US6569830B1 (en) * | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
| CA2369762A1 (en) * | 1999-04-16 | 2000-10-26 | Peter P. Lee | A method for improving the half-life of soluble viral-specific ligands on mucosal membranes |
| US6974700B2 (en) * | 1999-06-14 | 2005-12-13 | Martin Levine | Kit for use in predicting refractory periodontal disease |
| US20020051793A1 (en) * | 2000-09-12 | 2002-05-02 | Drabick Joseph J. | Lipoteichoic acid immunogenic compositions and methods of making and using thereof |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20030113350A1 (en) * | 2001-09-19 | 2003-06-19 | Fattom Ali I. | Glycoconjugate vaccines for use in immune-compromised populations |
| US6720160B2 (en) * | 2001-10-11 | 2004-04-13 | Helica Biosystems, Inc. | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals |
| US7169903B2 (en) * | 2001-12-21 | 2007-01-30 | Biosynexus Incorporated | Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria |
| AU2003203079B8 (en) * | 2002-02-04 | 2009-01-15 | Oncothyreon Inc. | Immunostimulatory, covalently lipidated oligonucleotides |
| FR2842210B1 (fr) * | 2002-07-09 | 2012-12-14 | Mutabilis | Determinants de pathogenicite utilisables comme cibles pour l'elaboration de moyens de prevention et de controle d'infections bacteriennes et/ou de la dissemination systemique |
| US20040109853A1 (en) * | 2002-09-09 | 2004-06-10 | Reactive Surfaces, Ltd. | Biological active coating components, coatings, and coated surfaces |
| WO2004096992A2 (en) * | 2003-04-25 | 2004-11-11 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore |
| US7422755B2 (en) * | 2004-01-15 | 2008-09-09 | The United States Of America As Represented By The Department Of Health And Human Services | Antimultiorganism glycoconjugate vaccine |
| KR100596443B1 (ko) * | 2004-04-27 | 2006-07-05 | 주식회사 하이닉스반도체 | 다수 뱅크 구조 디램을 위한 리프레시 제어회로 및 그 방법 |
| US20060134141A1 (en) * | 2004-12-14 | 2006-06-22 | Nabi Biopharmaceuticals | Glycoconjugate vaccines containing peptidoglycan |
| US20060228368A1 (en) * | 2005-04-07 | 2006-10-12 | Nabi Biopharmaceuticals | Method of protecting against staphylococcal infection |
| US20060269998A1 (en) * | 2005-04-15 | 2006-11-30 | North Carolina State University | Methods and compositions to modulate adhesion and stress tolerance in bacteria |
| US7521535B2 (en) * | 2006-09-20 | 2009-04-21 | The Board Of Regents For Oklahoma State University | Anti-microbial defensin-related peptides and methods of use |
-
2003
- 2003-12-01 WO PCT/US2003/038132 patent/WO2004050846A2/en not_active Ceased
- 2003-12-01 CA CA002507711A patent/CA2507711A1/en not_active Abandoned
- 2003-12-01 JP JP2004557434A patent/JP2006514636A/ja active Pending
- 2003-12-01 US US10/724,194 patent/US20040247605A1/en not_active Abandoned
- 2003-12-01 EP EP03796528A patent/EP1567868A4/en not_active Withdrawn
- 2003-12-01 AU AU2003298770A patent/AU2003298770A1/en not_active Withdrawn
-
2010
- 2010-01-29 AU AU2010200341A patent/AU2010200341A1/en not_active Abandoned
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