CY1110783T1 - Μονοκλωνικα αντισωματα κατα αυξητικου παραγοντα ηπατοκυτταρων - Google Patents

Μονοκλωνικα αντισωματα κατα αυξητικου παραγοντα ηπατοκυτταρων

Info

Publication number
CY1110783T1
CY1110783T1 CY20101100789T CY101100789T CY1110783T1 CY 1110783 T1 CY1110783 T1 CY 1110783T1 CY 20101100789 T CY20101100789 T CY 20101100789T CY 101100789 T CY101100789 T CY 101100789T CY 1110783 T1 CY1110783 T1 CY 1110783T1
Authority
CY
Cyprus
Prior art keywords
growth factor
monoclonal antibodies
antibodies against
against growth
pharmaceutical composition
Prior art date
Application number
CY20101100789T
Other languages
English (en)
Inventor
Kyung Jin Kim
Yi-Chi Su
Original Assignee
Galaxy Biotech, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35320045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110783(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galaxy Biotech, Llc filed Critical Galaxy Biotech, Llc
Publication of CY1110783T1 publication Critical patent/CY1110783T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/4753Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε ένα εξουδετερωτικό μονοκλωνικό αντίσωμα κατά αυξητικού παράγοντα ηπατοκυττάρων, σε μια φαρμακευτική σύνθεση που περιέχει αυτό, και σε μεθόδους θεραπευτικής αγωγής περιλαμβάνουσες τη χορήγηση μιας τέτοιας φαρμακευτικής σύνθεσης σε έναν ασθενή, τέτοιας όπως για την αναστολή γλοιοβλαστώματος.
CY20101100789T 2004-04-15 2010-08-30 Μονοκλωνικα αντισωματα κατα αυξητικου παραγοντα ηπατοκυτταρων CY1110783T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/825,060 US20040208876A1 (en) 2003-04-18 2004-04-15 Monoclonal antibodies to hepatocyte growth factor
EP04781281A EP1734995B1 (en) 2004-04-15 2004-08-13 Monoclonal antibodies to hepatocyte growth factor

Publications (1)

Publication Number Publication Date
CY1110783T1 true CY1110783T1 (el) 2015-06-10

Family

ID=35320045

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100789T CY1110783T1 (el) 2004-04-15 2010-08-30 Μονοκλωνικα αντισωματα κατα αυξητικου παραγοντα ηπατοκυτταρων

Country Status (26)

Country Link
US (5) US20040208876A1 (el)
EP (2) EP2204191A1 (el)
JP (2) JP4594381B2 (el)
KR (1) KR101072736B1 (el)
CN (1) CN1964738A (el)
AT (1) ATE473760T1 (el)
AU (1) AU2004319276C1 (el)
BR (1) BRPI0418745A (el)
CA (1) CA2563080C (el)
CR (1) CR8698A (el)
CY (1) CY1110783T1 (el)
DE (1) DE602004028168D1 (el)
DK (1) DK1734995T3 (el)
ES (1) ES2346886T3 (el)
HK (1) HK1094167A1 (el)
HR (1) HRP20100521T1 (el)
IL (1) IL178474A (el)
MX (1) MXPA06011822A (el)
NO (1) NO20065227L (el)
NZ (1) NZ550324A (el)
PL (1) PL1734995T3 (el)
PT (1) PT1734995E (el)
RU (1) RU2361879C2 (el)
SI (1) SI1734995T1 (el)
WO (1) WO2005107800A1 (el)
ZA (1) ZA200609407B (el)

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Also Published As

Publication number Publication date
EP2204191A1 (en) 2010-07-07
HRP20100521T1 (hr) 2010-10-31
DE602004028168D1 (de) 2010-08-26
EP1734995A1 (en) 2006-12-27
US20040208876A1 (en) 2004-10-21
US7687063B2 (en) 2010-03-30
CA2563080C (en) 2015-01-27
US20090104192A1 (en) 2009-04-23
RU2361879C2 (ru) 2009-07-20
IL178474A (en) 2011-04-28
BRPI0418745A (pt) 2007-12-11
ATE473760T1 (de) 2010-07-15
EP1734995B1 (en) 2010-07-14
IL178474A0 (en) 2007-02-11
CR8698A (es) 2007-12-17
JP4594381B2 (ja) 2010-12-08
PL1734995T3 (pl) 2010-12-31
CA2563080A1 (en) 2005-11-17
AU2004319276B2 (en) 2010-08-26
WO2005107800A1 (en) 2005-11-17
SI1734995T1 (sl) 2010-09-30
US7494650B2 (en) 2009-02-24
AU2004319276C1 (en) 2011-03-03
NZ550324A (en) 2009-12-24
HK1094167A1 (en) 2007-03-23
ES2346886T3 (es) 2010-10-21
KR101072736B1 (ko) 2011-10-11
NO20065227L (no) 2007-01-10
KR20070012711A (ko) 2007-01-26
JP2011012067A (ja) 2011-01-20
JP2007532643A (ja) 2007-11-15
RU2006140257A (ru) 2008-05-20
ZA200609407B (en) 2008-07-30
US20080019966A1 (en) 2008-01-24
CN1964738A (zh) 2007-05-16
EP1734995A4 (en) 2007-04-25
US20120064066A1 (en) 2012-03-15
US20070160613A1 (en) 2007-07-12
DK1734995T3 (da) 2010-10-25
PT1734995E (pt) 2010-08-18
AU2004319276A1 (en) 2005-11-17
MXPA06011822A (es) 2007-03-23

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