DK1684869T3 - Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme - Google Patents

Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme

Info

Publication number
DK1684869T3
DK1684869T3 DK04810517.5T DK04810517T DK1684869T3 DK 1684869 T3 DK1684869 T3 DK 1684869T3 DK 04810517 T DK04810517 T DK 04810517T DK 1684869 T3 DK1684869 T3 DK 1684869T3
Authority
DK
Denmark
Prior art keywords
therapy
antibody
cell
subject
cancer diseases
Prior art date
Application number
DK04810517.5T
Other languages
English (en)
Inventor
Li Long
Mohammad Luqman
Asha Yabannavar
Isabel Zaror
Original Assignee
Novartis Vaccines & Diagnostic
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic, Xoma Technology Ltd filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1684869T3 publication Critical patent/DK1684869T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
DK04810517.5T 2003-11-04 2004-11-04 Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme DK1684869T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US51733703P 2003-11-04 2003-11-04
US52557903P 2003-11-26 2003-11-26
US56571004P 2004-04-27 2004-04-27
US61388504P 2004-09-28 2004-09-28
PCT/US2004/037159 WO2005044307A2 (en) 2003-11-04 2004-11-04 Methods of therapy for b cell-related cancers

Publications (1)

Publication Number Publication Date
DK1684869T3 true DK1684869T3 (da) 2011-10-31

Family

ID=34577851

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04810517.5T DK1684869T3 (da) 2003-11-04 2004-11-04 Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme

Country Status (11)

Country Link
US (1) US20070098718A1 (da)
EP (3) EP1844815B1 (da)
JP (2) JP4810431B2 (da)
AT (1) ATE516819T1 (da)
CA (1) CA2544368C (da)
CY (1) CY1112473T1 (da)
DK (1) DK1684869T3 (da)
HK (1) HK1106736A1 (da)
PL (1) PL1684869T3 (da)
PT (1) PT1684869E (da)
WO (1) WO2005044307A2 (da)

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Also Published As

Publication number Publication date
JP2011105772A (ja) 2011-06-02
WO2005044307A2 (en) 2005-05-19
PT1684869E (pt) 2011-09-16
PL1684869T3 (pl) 2011-12-30
CA2544368A1 (en) 2005-05-19
CY1112473T1 (el) 2015-12-09
CA2544368C (en) 2014-04-01
EP1684869B1 (en) 2011-07-20
EP1844815A1 (en) 2007-10-17
WO2005044307A3 (en) 2005-08-25
US20070098718A1 (en) 2007-05-03
EP2236172A1 (en) 2010-10-06
HK1106736A1 (en) 2008-03-20
ATE516819T1 (de) 2011-08-15
JP4810431B2 (ja) 2011-11-09
EP1844815B1 (en) 2011-09-14
JP2007513073A (ja) 2007-05-24
EP1684869A2 (en) 2006-08-02

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